{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:14:01Z","timestamp":1791220441772,"version":"4.1.0"},"reference-count":50,"publisher":"The Company of Biologists","issue":"5","license":[{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,3,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Extracellular acid\u2013base balance in decapod crustaceans is influenced by water salinity, although the nature of this relationship is unclear. In euryhaline crabs, a decrease in salinity results in a metabolic alkalosis in the haemolymph and an increase in salinity results in a metabolic acidosis. Alterations in acid\u2013base status by external changes in salinity are thought to be secondary to the adjustments required for ionic and osmotic regulation. In the present study, acid\u2013base adjustments in the haemolymph of Eriocheir sinensis after transfer to 30 % sea water accompanied alterations in muscle pH and [HCO3\u2212], as an initial acidosis coincided with an alkalosis in the leg muscle. By 48 h transfer, haemolymph pH increased as muscle pH and HCO3\u2212 declined. Haemolymph [Cl\u2212] decreased significantly 3 h after transfer to a new steady state but haemolymph [Na+] and muscle [Na+] and [Cl\u2212] remained unchanged. Muscle free amino acid concentration increased twofold 6 h after transfer, followed by a 2.5-fold increase in the haemolymph after 24 h. In contrast, 30 % sea water had no effect on haemolymph acid\u2013base adjustments in the osmoconforming crab, Necora puber, which lacks ion and osmo-regulatory mechansims. Collectively these observations support the view that salinity-induced alterations in acid\u2013base status are caused by adjustments consistent with cell volume regulation.<\/jats:p>","DOI":"10.1242\/jeb.204.5.1003","type":"journal-article","created":{"date-parts":[[2021,4,25]],"date-time":"2021-04-25T04:44:38Z","timestamp":1619325878000},"page":"1003-1011","source":"Crossref","is-referenced-by-count":78,"title":["Effects of Water Salinity on Acid\u2013Base Balance in Decapod Crustaceans"],"prefix":"10.1242","volume":"204","author":[{"given":"N. M.","family":"Whiteley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. L.","family":"Scott","sequence":"additional","affiliation":[{"name":"University of Wales Bangor School of Biological Sciences , , Gwynedd LL57 2UW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. J.","family":"Breeze","sequence":"additional","affiliation":[{"name":"University of Wales Bangor School of Biological Sciences , , Gwynedd LL57 2UW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Mccann","sequence":"additional","affiliation":[{"name":"University of Wales Bangor School of Biological Sciences , , Gwynedd LL57 2UW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[2001,3,1]]},"reference":[{"key":"2024121805211574200_JEXBIO_204_5_1003C1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1042\/bj2820789","article-title":"The role of cell swelling in the stimulation of glycogen synthesis by insulin","volume":"282","author":"Al-Habori","year":"1992","journal-title":"Biochem. 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