{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:54:02Z","timestamp":1790142842295,"version":"4.0.1"},"reference-count":44,"publisher":"The Company of Biologists","issue":"4","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2019\/16805-4"],"award-info":[{"award-number":["2019\/16805-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2023\/09816-5"],"award-info":[{"award-number":["2023\/09816-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2022\/08232-7"],"award-info":[{"award-number":["2022\/08232-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2023\/09792-9"],"award-info":[{"award-number":["2023\/09792-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["303839\/2019-8"],"award-info":[{"award-number":["303839\/2019-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NOVO Nordisk"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Catecholamines may react with other molecules to produce catecholamine derivatives. For example, nitric oxide may induce nitration of dopamine to form 6-nitrodopamine (6-ND). The endogenous production of such a novel catecholamine has been demonstrated in the mammalian and reptilian cardiovascular system, and in vitro studies demonstrate that 6-ND relaxes pre-contracted aortic rings, and acts as a potent chronotropic agent. So far, however, the in vivo effects of 6-ND remain to be characterised in whole organisms. Using South American rattlesnakes (Crotalus durissus), we measured the endogenous production of 6-ND and other catecholamine derivatives in different tissues of the cardiovascular system and the intercostal muscle. We also used myography to measure the vascular reactivity of the mesenteric artery to 6-ND, and we utilised anaesthetised individuals to measure haemodynamic responses to bolus injections of 6-ND (1\u2005\u03bcmol\u00a0kg\u22121). Except for blood plasma, 6-ND was detected in all tissues studied, and the addition of l-NAME, a blocker of nitric oxide synthesis, did not alter the production of 6-ND, indicating there are alternative biosynthetic pathways. The isolated mesenteric artery contracted in the presence of adrenaline, dopamine, noradrenaline and 6-ND. We also observed a potentiation of the noradrenergic stimulation in the presence of 6-ND. Finally, injection of 6-ND elicited a small but significant reduction in the mesenteric conductance. It is likely that 6-ND per se exerts small effects on overall haemodynamics, but synergises with noradrenaline and possibly other catecholamines to enhance cardiovascular regulation.<\/jats:p>","DOI":"10.1242\/jeb.251103","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:09:41Z","timestamp":1768820981000},"source":"Crossref","is-referenced-by-count":4,"title":["The effects of 6-nitrodopamine on the systemic vasculature of South American rattlesnakes"],"prefix":"10.1242","volume":"229","author":[{"given":"Mariana G.","family":"de Oliveira","sequence":"first","affiliation":[{"name":"S\u00e3o Francisco University 1 Laboratory of Pharmacology , , Bragan\u00e7a Paulista 12916-900, SP ,","place":["Brazil"]},{"name":"University of Campinas 2 Department of Pharmacology, Faculty of Medical Sciences , , Campinas 13083-888, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samanta A.","family":"Castro","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos 3 Department of Physiological Sciences , , S\u00e3o Carlos 13565-905, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Campos","sequence":"additional","affiliation":[{"name":"University of Campinas 2 Department of Pharmacology, Faculty of Medical Sciences , , Campinas 13083-888, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Vivi","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos 3 Department of Physiological Sciences , , S\u00e3o Carlos 13565-905, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9o A. C.","family":"Leite","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos 3 Department of Physiological Sciences , , S\u00e3o Carlos 13565-905, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto","family":"De Nucci","sequence":"additional","affiliation":[{"name":"University of Campinas 2 Department of Pharmacology, Faculty of Medical Sciences , , Campinas 13083-888, SP ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Wang","sequence":"additional","affiliation":[{"name":"Aarhus University 4 Section for Zoophysiology, Department of Biosciences , , 8000 Aarhus ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5436-7102","authenticated-orcid":false,"given":"Renato","family":"Filogonio","sequence":"additional","affiliation":[{"name":"University of Campinas 2 Department of Pharmacology, Faculty of Medical Sciences , , Campinas 13083-888, SP ,","place":["Brazil"]},{"name":"University of Missouri 5 Division of Biological Sciences , , Columbia, MO 65201 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"2026021905522994000_JEB251103C1","doi-asserted-by":"publisher","first-page":"e70124","DOI":"10.1111\/bcpt.70124","article-title":"Cyanide beyond toxicity: a systematic review of its effects on vascular function","volume":"137","author":"Alan-Albayrak","year":"2025","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"2026021905522994000_JEB251103C2","doi-asserted-by":"publisher","first-page":"bio057042","DOI":"10.1242\/bio.057042","article-title":"The basal release of endothelium-derived catecholamines regulates the contractions of Chelonoidis carbonaria aorta caused by electrical-field stimulation","volume":"10","author":"Britto-J\u00fanior","year":"2021","journal-title":"Biol. Open"},{"key":"2026021905522994000_JEB251103C3","doi-asserted-by":"publisher","first-page":"119425","DOI":"10.1016\/j.lfs.2021.119425","article-title":"6-Nitrodopamine is released by human umbilical cord vessels and modulates vascular reactivity","volume":"276","author":"Britto-J\u00fanior","year":"2021","journal-title":"Life Sci."},{"key":"2026021905522994000_JEB251103C4","doi-asserted-by":"publisher","first-page":"174544","DOI":"10.1016\/j.ejphar.2021.174544","article-title":"6-Nitrodopamine is an endogenous mediator of rat isolated epididymal vas deferens contractions induced by electric-field stimulation","volume":"911","author":"Britto-J\u00fanior","year":"2021","journal-title":"Eur. J. Pharmacol."},{"key":"2026021905522994000_JEB251103C5","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1111\/andr.13263","article-title":"6-nitrodopamine is a major endogenous modulator of human vas deferens contractility","volume":"10","author":"Britto-J\u00fanior","year":"2022","journal-title":"Andrology"},{"key":"2026021905522994000_JEB251103C6","doi-asserted-by":"publisher","first-page":"109403","DOI":"10.1016\/j.cbpc.2022.109403","article-title":"6-Nitrodopamine is an endogenous selective dopamine receptor antagonist in Chelonoidis carbonaria aorta","volume":"260","author":"Britto-J\u00fanior","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"2026021905522994000_JEB251103C7","doi-asserted-by":"publisher","first-page":"120879","DOI":"10.1016\/j.lfs.2022.120879","article-title":"6-NitroDopamine is an endogenous modulator of rat heart chronotropism","volume":"307","author":"Britto-J\u00fanior","year":"2022","journal-title":"Life Sci."},{"key":"2026021905522994000_JEB251103C8","doi-asserted-by":"publisher","first-page":"e12622","DOI":"10.1590\/1414-431x2023e12622","article-title":"Relaxation of thoracic aorta and pulmonary artery rings of marmosets (Callithrix spp.) by endothelium-derived 6-nitrodopamine","volume":"56","author":"Britto-J\u00fanior","year":"2023","journal-title":"Braz. J. Med. Biol. Res."},{"key":"2026021905522994000_JEB251103C9","doi-asserted-by":"publisher","first-page":"2555","DOI":"10.1007\/s00210-023-02478-6","article-title":"6-Nitrodopamine potentiates contractions of rat isolated vas deferens induced by noradrenaline, adrenaline, dopamine and electric field stimulation","volume":"396","author":"Britto-J\u00fanior","year":"2023","journal-title":"Naunyn. Schmiedebergs Arch. Pharmacol."},{"key":"2026021905522994000_JEB251103C10","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1007\/s00210-023-02394-9","article-title":"Investigation on the positive chronotropic action of 6-nitrodopamine in the rat isolated atria","volume":"396","author":"Britto-J\u00fanior","year":"2023","journal-title":"Naunyn. Schmiedebergs Arch. Pharmacol."},{"key":"2026021905522994000_JEB251103C11","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.3390\/life13102012","article-title":"6-Nitrodopamine is the most potent endogenous positive inotropic agent in the isolated rat heart","volume":"13","author":"Britto-J\u00fanior","year":"2023","journal-title":"Life (Basel)"},{"key":"2026021905522994000_JEB251103C12","doi-asserted-by":"publisher","first-page":"123504","DOI":"10.1016\/j.lfs.2025.123504","article-title":"6-Cyanodopamine as an endogenous modulator of heart chronotropism and inotropism","volume":"366-367","author":"Britto-J\u00fanior","year":"2025","journal-title":"Life Sci."},{"key":"2026021905522994000_JEB251103C13","doi-asserted-by":"publisher","first-page":"e0196123","DOI":"10.1371\/journal.pone.0196123","article-title":"Electrical field stimulation-induced contractions on Pantherophis guttatus corpora cavernosa and aortae","volume":"13","author":"Campos","year":"2018","journal-title":"PLoS ONE"},{"key":"2026021905522994000_JEB251103C14","doi-asserted-by":"publisher","first-page":"e0203573","DOI":"10.1371\/journal.pone.0203573","article-title":"Electrical field-induced contractions on Crotalus durissus terrificus and Bothrops jararaca aortae are caused by endothelium-derived catecholamine","volume":"13","author":"Campos","year":"2018","journal-title":"PLoS ONE"},{"key":"2026021905522994000_JEB251103C15","doi-asserted-by":"publisher","first-page":"108763","DOI":"10.1016\/j.cbpc.2020.108763","article-title":"Endothelium modulates electrical field stimulation-induced contractions of Chelonoidis carbonaria aortic rings","volume":"233","author":"Campos","year":"2020","journal-title":"Comp. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"2026021905522994000_JEB251103C16","doi-asserted-by":"publisher","first-page":"122668","DOI":"10.1016\/j.jchromb.2021.122668","article-title":"Quantification of 6-nitrodopamine in Krebs-Henseleit's solution by LC-MS\/MS for the assessment of its basal release from Chelonoidis carbonaria aortae in vitro","volume":"1173","author":"Campos","year":"2021","journal-title":"J. Chromatogr. B"},{"key":"2026021905522994000_JEB251103C17","doi-asserted-by":"publisher","first-page":"1616","DOI":"10.1111\/j.1743-6109.2011.02246.x","article-title":"Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of corpus cavernosum from the South American rattlesnake Crotalus durissus terrificus","volume":"8","author":"Capel","year":"2011","journal-title":"J. Sex. Med."},{"key":"2026021905522994000_JEB251103C18","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1086\/718292","article-title":"Role of nitric oxide in the cardiovascular system of South American rattlesnakes (Crotalus durissus)","volume":"95","author":"Castro","year":"2022","journal-title":"Physiol. Biochem. Zool."},{"key":"2026021905522994000_JEB251103C19","doi-asserted-by":"publisher","first-page":"111421","DOI":"10.1016\/j.cbpa.2023.111421","article-title":"Adrenergic control of functional characteristics of the cardiovascular system in the South American rattlesnake, Crotalus durissus","volume":"281","author":"Castro","year":"2023","journal-title":"Comp. Biochem. Physiol. A. Mol. Integr. Physiol."},{"key":"2026021905522994000_JEB251103C20","doi-asserted-by":"publisher","first-page":"121801","DOI":"10.1016\/j.lfs.2023.121801","article-title":"Release of 6-nitrodopamine from human popliteal artery and vein","volume":"326","author":"de Oliveira","year":"2023","journal-title":"Life Sci."},{"key":"2026021905522994000_JEB251103C21","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/0968-0896(95)00083-S","article-title":"Nitric oxide-induced nitration of catecholamine neurotransmitters: a key to neuronal degeneration?","volume":"3","author":"d'Ischia","year":"1995","journal-title":"Bioorg. Med. Chem."},{"key":"2026021905522994000_JEB251103C22","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s00360-016-1008-y","article-title":"Vagal tone regulates cardiac shunts during activity and at low temperatures in the south American rattlesnake, Crotalus durissus","volume":"186","author":"Filogonio","year":"2016","journal-title":"J. Comp. Physiol. B"},{"key":"2026021905522994000_JEB251103C23","doi-asserted-by":"publisher","first-page":"242","DOI":"10.2994\/SAJH-D-18-00013.1","article-title":"Cooling and warming rates are unaffected by autonomic vascular control in the south American rattlesnake (Crotalus durissus)","volume":"14","author":"Filogonio","year":"2019","journal-title":"South Am. J. Herpetol."},{"key":"2026021905522994000_JEB251103C24","doi-asserted-by":"publisher","first-page":"R156","DOI":"10.1152\/ajpregu.00310.2019","article-title":"Cholinergic regulation along the pulmonary arterial tree of the south American rattlesnake: vascular reactivity, muscarinic receptors, and vagal innervation","volume":"319","author":"Filogonio","year":"2020","journal-title":"Am. J. Physiol.-Regul. Integr. Comp. Physiol."},{"key":"2026021905522994000_JEB251103C25","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1111\/andr.13836","article-title":"6-Nitrodopamine is an endogenous mediator of rat seminal vesicles contractility","volume":"13","author":"Fuguhara","year":"2025","journal-title":"Andrology"},{"key":"2026021905522994000_JEB251103C26","doi-asserted-by":"publisher","first-page":"1557997","DOI":"10.3389\/fphar.2025.1557997","article-title":"Cardiovascular effects of 6-nitrodopamine, adrenaline, noradrenaline, and dopamine in normotensive and hypertensive rats","volume":"16","author":"Fuguhara","year":"2025","journal-title":"Front. Pharmacol."},{"key":"2026021905522994000_JEB251103C27","doi-asserted-by":"publisher","first-page":"R456","DOI":"10.1152\/ajpregu.00417.2004","article-title":"Cardiovascular actions of rattlesnake bradykinin ([Val1 ,Thr6 ]bradykinin) in the anesthetized South American rattlesnake Crotalus durissus terrificus","volume":"288","author":"Galli","year":"2005","journal-title":"Am. J. Physiol.-Regul. Integr. Comp. Physiol."},{"key":"2026021905522994000_JEB251103C28","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s00360-005-0476-2","article-title":"The role of nitric oxide in the regulation of the systemic and pulmonary vasculature of the rattlesnake, Crotalus durissus terrificus","volume":"175","author":"Galli","year":"2005","journal-title":"J. Comp. Physiol. B"},{"key":"2026021905522994000_JEB251103C29","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s10286-010-0065-7","article-title":"Catecholamines 101","volume":"20","author":"Goldstein","year":"2010","journal-title":"Clin. Auton. Res."},{"key":"2026021905522994000_JEB251103C30","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1152\/physiol.00018.2024","article-title":"Regulation of cardiac Function by the autonomic nervous system","volume":"40","author":"Hafez","year":"2025","journal-title":"Physiology"},{"key":"2026021905522994000_JEB251103C31","first-page":"4","article-title":"Inhibition of the sympathetic nervous system by dopamine","volume":"216","author":"Ilhan","year":"1975","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"2026021905522994000_JEB251103C32","doi-asserted-by":"publisher","first-page":"109471","DOI":"10.1016\/j.cbpc.2022.109471","article-title":"Release of 6-nitrodopamine modulates vascular reactivity of Pantherophis guttatus aortic rings","volume":"262","author":"Lima","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"2026021905522994000_JEB251103C33","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1152\/physrev.1998.78.1.189","article-title":"Dopamine receptors: from structure to function","volume":"78","author":"Missale","year":"1998","journal-title":"Physiol. Rev."},{"key":"2026021905522994000_JEB251103C34","doi-asserted-by":"publisher","first-page":"e3000410","DOI":"10.1371\/journal.pbio.3000410","article-title":"The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research","volume":"18","author":"Percie Du Sert","year":"2020","journal-title":"PLoS Biol."},{"key":"2026021905522994000_JEB251103C35","doi-asserted-by":"publisher","first-page":"88","DOI":"10.5662\/wjm.v5.i2.88","article-title":"Past, present and future of cyanide antagonism research: From the early remedies to the current therapies","volume":"5","author":"Petrikovics","year":"2015","journal-title":"World J Methodol."},{"key":"2026021905522994000_JEB251103C36","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1007\/s00424-024-02985-2","article-title":"Basal release of 6-cyanodopamine from rat isolated vas deferens and its role on the tissue contractility","volume":"476","author":"Pozzo","year":"2024","journal-title":"Pflugers Arch."},{"key":"2026021905522994000_JEB251103C37","doi-asserted-by":"publisher","first-page":"e5691","DOI":"10.1002\/bmc.5691","article-title":"Measurement of 6-cyanodopamine, 6-nitrodopa, 6-nitrodopamine and 6-nitroadrenaline by LC\u2013MS\/MS in Krebs\u2013Henseleit solution. Assessment of basal release from rabbit isolated right atrium and ventricles","volume":"37","author":"Quirino","year":"2023","journal-title":"Biomed. Chromatogr."},{"key":"2026021905522994000_JEB251103C38","doi-asserted-by":"publisher","first-page":"e5896","DOI":"10.1002\/bmc.5896","article-title":"A LC\u2013MS\/MS method for the simultaneous determination of 6-cyanodopamine, 6-nitrodopamine, 6-nitrodopa, 6-nitroadrenaline and 6-bromodopamine in human plasma and its clinical application in patients with chronic kidney disease","volume":"38","author":"Ribeiro","year":"2024","journal-title":"Biomed. Chromatogr."},{"key":"2026021905522994000_JEB251103C39","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1080\/00397911.2016.1269350","article-title":"Catechol reactivity: Synthesis of dopamine derivatives substituted at the 6-position","volume":"47","author":"Rote","year":"2017","journal-title":"Synth. Commun."},{"key":"2026021905522994000_JEB251103C40","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1242\/jeb.024042","article-title":"The unequal influences of the left and right vagi on the control of the heart and pulmonary artery in the rattlesnake, Crotalus durissus","volume":"212","author":"Taylor","year":"2009","journal-title":"J. Exp. Biol."},{"key":"2026021905522994000_JEB251103C41","first-page":"21","article-title":"Blood pH and O2 homeostasis upon CO2 anesthesia in the rattlesnake (Crotalus durissus)","volume":"25","author":"Wang","year":"1993","journal-title":"The Snake"},{"key":"2026021905522994000_JEB251103C42","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-323-85492-4.00041-7","article-title":"Evolution of the cardiovascular autonomic nervous system in vertebrates","volume-title":"Primer on the Autonomic Nervous System","author":"Wang","year":"2023"},{"key":"2026021905522994000_JEB251103C43","doi-asserted-by":"publisher","first-page":"S171","DOI":"10.1164\/ajrccm.158.supplement_2.13tac140","article-title":"Autonomic regulation: i-NANC\/e-NANC","volume":"158","author":"Widdicombe","year":"1998","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"2026021905522994000_JEB251103C44","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1152\/physiol.00020.2023","article-title":"Endothelium-derived dopamine and 6-nitrodopamine in the cardiovascular system","volume":"39","author":"Zatz","year":"2024","journal-title":"Physiology"}],"container-title":["Journal of Experimental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/jeb\/article-pdf\/doi\/10.1242\/jeb.251103\/3681141\/jeb251103.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/jeb\/article-pdf\/doi\/10.1242\/jeb.251103\/3685703\/jeb251103.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/jeb\/article-pdf\/doi\/10.1242\/jeb.251103\/3685703\/jeb251103.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T10:52:42Z","timestamp":1771498362000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/jeb\/article\/229\/4\/jeb251103\/370732\/The-effects-of-6-nitrodopamine-on-the-systemic"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,15]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,2,15]]}},"URL":"https:\/\/doi.org\/10.1242\/jeb.251103","relation":{},"ISSN":["0022-0949","1477-9145"],"issn-type":[{"value":"0022-0949","type":"print"},{"value":"1477-9145","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,15]]},"article-number":"jeb251103"}}