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Further, we show that the floating head homeobox gene is required in axial mesoderm to repress the expression of both spadetail and papc, promoting notochord and blocking differentiation of paraxial mesoderm. The PAPC structural cell-surface protein may provide a link between regulatory transcription factors and the actual cell biological behaviors that execute morphogenesis during gastrulation.<\/jats:p>","DOI":"10.1242\/dev.125.17.3389","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T03:17:58Z","timestamp":1619407078000},"page":"3389-3397","source":"Crossref","is-referenced-by-count":198,"title":["Zebrafish <i>paraxial protocadherin<\/i> is a downstream target of <i>spadetail<\/i> involved in morphogenesis of gastrula mesoderm"],"prefix":"10.1242","volume":"125","author":[{"given":"Akihito","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Howard Hughes Medical Institute 1 , Department of Biological Chemistry, University of California, Los Angeles, California 90095-1662, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon L.","family":"Amacher","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience 2 , University of Oregon, Eugene, Oregon 97403-1254, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute 1 , Department of Biological Chemistry, University of California, Los Angeles, California 90095-1662, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Geissert","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute 1 , Department of Biological Chemistry, University of California, Los Angeles, California 90095-1662, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles B.","family":"Kimmel","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience 2 , University of Oregon, Eugene, Oregon 97403-1254, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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