{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:39:44Z","timestamp":1793162384674,"version":"4.5.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2007,3,8]],"date-time":"2007-03-08T00:00:00Z","timestamp":1173312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,3,8]],"date-time":"2007-03-08T00:00:00Z","timestamp":1173312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1245\/s10434-006-9330-3","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T18:29:59Z","timestamp":1173205799000},"page":"1825-1834","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["The Pylorus: Take It or Leave It? Systematic Review and Meta-Analysis of Pylorus-Preserving versus Standard Whipple Pancreaticoduodenectomy for Pancreatic or Periampullary Cancer"],"prefix":"10.1245","volume":"14","author":[{"given":"Paul J.","family":"Karanicolas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Briel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Pavan","family":"Koka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrin M.","family":"Payne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shona E.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Ping","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin-Wen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Bloechle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Joseph","family":"Paquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon H.","family":"Guyatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,3,8]]},"reference":[{"key":"9330_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3322\/canjclin.53.1.5","volume":"53","author":"A Jemal","year":"2003","unstructured":"Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ. Cancer statistics. CA Cancer J Clin 2003; 53:5\u201326","journal-title":"CA Cancer J Clin"},{"key":"9330_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1072-7515(99)00075-7","volume":"189","author":"SF Sener","year":"1999","unstructured":"Sener SF, Fremgen A, Menck HR, Winchester DP. Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985\u20131995, using the National Cancer Database. J Am Coll Surg 1999; 189:1\u20137","journal-title":"J Am Coll Surg"},{"key":"9330_CR3","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1046\/j.1365-2168.1998.00920.x","volume":"85","author":"M Hedberg","year":"1998","unstructured":"Hedberg M, Borgstrom A, Genell S, Janzon L. Survival following panceatic carcinoma: a follow-up study of all cases recorded in Malmo, Sweden, 1977\u20131991. Br J Surg 1998; 85:1641\u20134","journal-title":"Br J Surg"},{"key":"9330_CR4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/bjs.1800820137","volume":"82","author":"SR Bramhall","year":"1995","unstructured":"Bramhall SR, Allum WH, Jones AG, Allwood A, Cummins C, Neoptolemos JP. Treatment and survival in 13,560 patients with pancreatic cancer and incidence of the disease in the West Midlands. An epidemiological study. Br J Surg 1995; 82:111\u20135","journal-title":"Br J Surg"},{"key":"9330_CR5","first-page":"439","volume":"78","author":"W Kausch","year":"1912","unstructured":"Kausch W. Das Carcinom der Papilla duodeni und seine radikale Entfernung. Bruns Beitr Klin Chir 1912; 78:439\u201386","journal-title":"Bruns Beitr Klin Chir"},{"key":"9330_CR6","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1097\/00000658-193510000-00023","volume":"102","author":"AO Whipple","year":"1935","unstructured":"Whipple AO, al. e. Treatment of carcinoma of the ampulla of Vater. Ann Surg 1935; 102:763\u201379","journal-title":"Ann Surg"},{"key":"9330_CR7","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1002\/bjs.18003112406","volume":"31","author":"K Watson","year":"1944","unstructured":"Watson K. Carcinoma of the ampulla of Vater. Successful radical resection. Br J Surg 1944; 31:368\u201373","journal-title":"Br J Surg"},{"key":"9330_CR8","first-page":"959","volume":"146","author":"LW Traverso","year":"1978","unstructured":"Traverso LW, Longmire WPJ. Preservation of the pylorus in pancreaticoduodenectomy. Surg Gynecol Obstet 1978; 146:959\u201362","journal-title":"Surg Gynecol Obstet"},{"key":"9330_CR9","unstructured":"Carter D, Russell R, Pitt H (eds). Rob and Smith\u2019s Operative Surgery: Hepatobiliary and Pancreatic Surgery. 5th ed. London: Chapman & Hall, 1996"},{"key":"9330_CR10","unstructured":"Howard J, Idezuki Y, Ihse I, Prinz R (eds). Surgical Diseases of the Pancreas. 3rd ed. Baltimore: Williams & Wilkins, 1998"},{"key":"9330_CR11","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1016\/0895-4356(96)00057-1","volume":"49","author":"A Donner","year":"1996","unstructured":"Donner A, Klar N. The statistical analysis of kappa statistics in multiple samples. J Clin Epidemiol 1996; 49:1053\u20138","journal-title":"J Clin Epidemiol"},{"key":"9330_CR12","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/096228029300200202","volume":"2","author":"J Fleiss","year":"1993","unstructured":"Fleiss J. The statistical basis of meta-analysis. Stat Methods Med Res 1993; 2:121\u201345","journal-title":"Stat Methods Med Res"},{"key":"9330_CR13","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1136\/bmj.323.7303.42","volume":"323","author":"P J\u00fcni","year":"2001","unstructured":"J\u00fcni P, Altman DG, Egger M. Assessing the quality of controlled clinical trials. BMJ 2001; 323:42\u20136","journal-title":"BMJ"},{"key":"9330_CR14","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1001\/jama.282.11.1054","volume":"282","author":"P J\u00fcni","year":"1999","unstructured":"J\u00fcni P, Witschi A, Bloch R, Egger M. The hazards of scoring the quality of clinical trials for meta-analysis. JAMA 1999; 282:1054\u201360","journal-title":"JAMA"},{"key":"9330_CR15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1471-2288-5-13","volume":"5","author":"SP Hozo","year":"2005","unstructured":"Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Method 2005; 5:13","journal-title":"BMC Med Res Method"},{"key":"9330_CR16","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/0197-2456(87)90155-3","volume":"8","author":"K Dickerson","year":"1987","unstructured":"Dickerson K, Chan S, Chalmers T, Sacks H, Smith HJ. Publication bias and clinical trials. Control Clin Trials 1987; 8:343\u201353","journal-title":"Control Clin Trials"},{"key":"9330_CR17","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7:177\u201388","journal-title":"Control Clin Trials"},{"key":"9330_CR18","unstructured":"Breslow N, Day N. Combination of results from a series of 2\u00a0\u00d7\u00a02 tables; control of confounding. In: Statistical Methods in Cancer Research, vol. 1, The Analysis of Case-Control Studies. Lyon, France: International Agency for Research on Cancer, 1980:136\u201346"},{"key":"9330_CR19","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","volume":"21","author":"JP Higgins","year":"2002","unstructured":"Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21:1539\u201358","journal-title":"Stat Med"},{"key":"9330_CR20","first-page":"30","volume-title":"Clinincal Epidemiology: A Basic Science for Clinical Medicine","author":"D Sackett","year":"1991","unstructured":"Sackett D, Haynes R, Guyatt G, Tugwell P. Clinincal Epidemiology: A Basic Science for Clinical Medicine. 2nd ed. Boston: Little, Brown, 1991:30","edition":"2"},{"key":"9330_CR21","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1001\/jama.281.19.1836","volume":"281","author":"G Guyatt","year":"1999","unstructured":"Guyatt G, Sinclair J, Cook D, Glasziou P. Users\u2019 guides to the medical literature: XVI. How to use a treatment recommendation. Evidence-Based Medicine Working Group. JAMA 1999; 281:1836\u201343","journal-title":"JAMA"},{"key":"9330_CR22","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","volume":"328","author":"D Atkins","year":"2004","unstructured":"Atkins D, Best D, Briss PA, et al. Grading quality of evidence and strength of recommendations. BMJ 2004; 328:1490\u20134","journal-title":"BMJ"},{"key":"9330_CR23","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1378\/chest.129.1.174","volume":"129","author":"GH Guyatt","year":"2006","unstructured":"Guyatt GH, Gutterman D, Baumann MH, et al. Grading strength of recommendations and quality of evidence in clinical guidelines. Chest 2006; 129:174\u201381","journal-title":"Chest"},{"key":"9330_CR24","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.ctrv.2005.04.005","volume":"31","author":"RH Bell Jr","year":"2005","unstructured":"Bell RH Jr. Pancreaticoduodenectomy with or without pylorus preservation have similar outcomes. Cancer Treat Rev 2005; 31:328\u201331","journal-title":"Cancer Treat Rev"},{"key":"9330_CR25","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1046\/j.1365-2168.1999.01074.x","volume":"86","author":"PW Lin","year":"1999","unstructured":"Lin PW, Lin YJ. Prospective randomized comparison between pylorus-preserving and standard pancreaticoduodenectomy. Br J Surg 1999; 86:603\u20137","journal-title":"Br J Surg"},{"key":"9330_CR26","first-page":"1601","volume":"52","author":"PW Lin","year":"2005","unstructured":"Lin PW, Shan YS, Lin YJ, Hung CJ. Pancreaticoduodenectomy for pancreatic head cancer: PPPD versus Whipple procedure. Hepatogastroenterology 2005; 52:1601\u20134","journal-title":"Hepatogastroenterology"},{"key":"9330_CR27","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1097\/01.sla.0000143248.71964.29","volume":"240","author":"KT Tran","year":"2004","unstructured":"Tran KT, Smeenk HG, van Eijck CH, et al. Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors. Ann Surg 2004; 240:738\u201345","journal-title":"Ann Surg"},{"key":"9330_CR28","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1007\/PL00002580","volume":"70","author":"FA Wenger","year":"1999","unstructured":"Wenger FA, Jacobi CA, Haubold K, Zieren HU, Muller JM. Gastrointestinal quality of life after duodenopancreatectomy in pancreatic carcinoma. Preliminary results of a prospective randomized study: pancreatoduodenectomy or pylorus-preserving pancreatoduodenectomy. Chirurg 1999; 70:1454\u20139","journal-title":"Chirurg"},{"key":"9330_CR29","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1002\/bjs.4881","volume":"92","author":"CA Seiler","year":"2005","unstructured":"Seiler CA, Wagner M, Bachmann T, et al. Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results. Br J Surg 2005; 92:547\u201356","journal-title":"Br J Surg"},{"key":"9330_CR30","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1024\/1023-9332.6.5.275","volume":"6","author":"CA Seiler","year":"2000","unstructured":"Seiler CA, Wagner M, Schaller B, Sadowski C, Kulli C, Buchler MW. Pylorus preserving or classical Whipple operation in tumors. Initial clinical results of a prospective randomized study. Swiss Surg 2000; 6:275\u201382","journal-title":"Swiss Surg"},{"key":"9330_CR31","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/S1091-255X(00)80084-0","volume":"4","author":"CA Seiler","year":"2000","unstructured":"Seiler CA, Wagner M, Sadowski C, Kulli C, Buchler MW. Randomized prospective trial of pylorus-preserving vs. classic duodenopancreatectomy (Whipple procedure): initial clinical results. J Gastrointest Surg 2000; 4:443\u201352","journal-title":"J Gastrointest Surg"},{"key":"9330_CR32","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1159\/000012471","volume":"14","author":"K-J Paquet","year":"1998","unstructured":"Paquet K-J. Comparison of Whipple\u2019s pancreaticoduodenectomy with the pylorus- preserving pancreaticoduodenectomy\u2014a prospectively controlled, randomized long-term trial. Chir Gastroenterol 1998; 14:54\u20138","journal-title":"Chir Gastroenterol"},{"key":"9330_CR33","doi-asserted-by":"crossref","unstructured":"Bloechle C, Broering DC, Latuske C, Latuske M, v Schrenck T, Izbicki JR. Prospective randomized study to evaluate quality of life after partial pancreatoduodenectomy according to whipple versus pylorus preserving pancreatoduodenectomy according to longmire-traverso for periampullary carcinoma. Deutsche Gesellschaft Chir 1999; (Suppl 1):661\u20134","DOI":"10.1007\/978-3-642-60133-0_133"},{"key":"9330_CR34","first-page":"645","volume":"105","author":"KW Sharp","year":"1988","unstructured":"Sharp KW, Ross CB, Halter SA, Morrison JG, Richards WO. Pancreaticoduodenectomy with pyloric preservation for carcinoma of the pancreas: a cautionary note. Surgery 1988; 105:645\u201353","journal-title":"Surgery"},{"key":"9330_CR35","first-page":"2689","volume":"50","author":"AR Moosa","year":"1982","unstructured":"Moosa AR. Pancreatic cancer. Approach to diagnosis, selection for surgery and choice of operation. Cancer 1982; 50:2689\u201398","journal-title":"Cancer"},{"key":"9330_CR36","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1136\/bmj.330.7482.88","volume":"330","author":"PJ Devereaux","year":"2005","unstructured":"Devereaux PJ, Bhandari M, Clarke M, et al. Need for expertise based randomised controlled trials. BMJ 2005; 330:88","journal-title":"BMJ"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-006-9330-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-006-9330-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-006-9330-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-006-9330-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T22:03:41Z","timestamp":1652825021000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-006-9330-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,8]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["9330"],"URL":"https:\/\/doi.org\/10.1245\/s10434-006-9330-3","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1089127.542895","asserted-by":"object"}]},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,8]]},"assertion":[{"value":"24 August 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2006","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2007","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}