{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:00:17Z","timestamp":1792054817414,"version":"4.4.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2008,7,22]],"date-time":"2008-07-22T00:00:00Z","timestamp":1216684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1245\/s10434-008-0001-4","type":"journal-article","created":{"date-parts":[[2008,7,21]],"date-time":"2008-07-21T13:55:00Z","timestamp":1216648500000},"page":"2915-2926","source":"Crossref","is-referenced-by-count":80,"title":["Does Surgical Resection of Pulmonary Metastases of Head and Neck Cancer Improve Survival?"],"prefix":"10.1245","volume":"15","author":[{"given":"Hauke","family":"Winter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Meimarakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Hummel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"R\u00fcttinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Zilbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Stelter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fritz","family":"Spelsberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Walter","family":"Jauch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolph","family":"Hatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"L\u00f6he","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,7,22]]},"reference":[{"key":"1_CR1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1159\/000055740","volume":"63","author":"A Ferlito","year":"2001","unstructured":"Ferlito A, Shaha AR, Silver CE, et\u00a0al. Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec 2001;63:202\u20137.","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"1_CR2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/1097-0142(197401)33:1<127::AID-CNCR2820330119>3.0.CO;2-L","volume":"33","author":"JC Probert","year":"1974","unstructured":"Probert JC, Thompson RW, Bagshaw MA. Patterns of spread of distant metastases in head and neck cancer. Cancer 1974; 33:127\u201333.","journal-title":"Cancer"},{"key":"1_CR3","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/archotol.1987.01860070076020","volume":"113","author":"P Zbaren","year":"1987","unstructured":"Zbaren P, Lehmann W. Frequency and sites of distant metastases in head and neck squamous cell carcinoma. An analysis of 101 cases at autopsy. Arch Otolaryngol Head Neck Surg 1987; 113:762\u20134.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"1_CR4","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/1097-0142(19840115)53:2<342::AID-CNCR2820530228>3.0.CO;2-9","volume":"53","author":"RJ Papac","year":"1984","unstructured":"Papac RJ. Distant metastases from head and neck cancer. Cancer 1984; 53:342\u20135.","journal-title":"Cancer"},{"key":"1_CR5","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/S0002-9610(05)80714-7","volume":"164","author":"RK Finley III","year":"1992","unstructured":"Finley RK III, Verazin GT, Driscoll DL, et\u00a0al. Results of surgical resection of pulmonary metastases of squamous cell carcinoma of the head and neck. Am J Surg 1992; 164:594\u20138.","journal-title":"Am J Surg"},{"key":"1_CR6","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0002-9610(88)80282-4","volume":"156","author":"TM Mazer","year":"1988","unstructured":"Mazer TM, Robbins KT, McMurtrey MJ, et\u00a0al. Resection of pulmonary metastases from squamous carcinoma of the head and neck. Am J Surg 1988; 156:238\u201342.","journal-title":"Am J Surg"},{"key":"1_CR7","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/0360-3016(91)90669-U","volume":"21","author":"SA Leibel","year":"1991","unstructured":"Leibel SA, Scott CB, Mohiuddin M, et\u00a0al. The effect of local-regional control on distant metastatic dissemination in carcinoma of the head and neck: results of an analysis from the RTOG head and neck database. Int J Radiat Oncol Biol Phys 1991; 21:549\u201356.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1_CR8","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0022-5223(19)35939-2","volume":"92","author":"EA Rendina","year":"1986","unstructured":"Rendina EA, de Vincentiis M, Primerano G, et\u00a0al. Pulmonary resection for metastatic laryngeal carcinoma. J Thorac Cardiovasc Surg 1986; 92:114\u20137.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1_CR9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/1097-0142(197707)40:1<145::AID-CNCR2820400124>3.0.CO;2-9","volume":"40","author":"OR Merino","year":"1977","unstructured":"Merino OR, Lindberg RD, Fletcher GH. An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer 1977; 40:145\u201351.","journal-title":"Cancer"},{"key":"1_CR10","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/hed.2890060305","volume":"6","author":"B Vikram","year":"1984","unstructured":"Vikram B, Strong EW, Shah JP, et\u00a0al. Failure at distant sites following multimodality treatment for advanced head and neck cancer. Head Neck Surg 1984; 6:730\u20133.","journal-title":"Head Neck Surg"},{"key":"1_CR11","first-page":"206","volume":"25","author":"GP Laroche","year":"1982","unstructured":"Laroche GP. Associated laryngeal and lung carcinoma. Can J Surg 1982; 25:206\u20137.","journal-title":"Can J Surg"},{"key":"1_CR12","first-page":"54","volume":"22","author":"RI Mitchell","year":"1979","unstructured":"Mitchell RI. Multiple primary cancers involving the lung. Can J Surg 1979; 22:54\u20139.","journal-title":"Can J Surg"},{"key":"1_CR13","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0196-0709(97)90059-4","volume":"18","author":"K Nibu","year":"1997","unstructured":"Nibu K, Nakagawa K, Kamata S, et\u00a0al. Surgical treatment for pulmonary metastases of squamous cell carcinoma of the head and neck. Am J Otolaryngol 1997; 18:391\u20135.","journal-title":"Am J Otolaryngol"},{"key":"1_CR14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00000658-197803000-00004","volume":"187","author":"WG Cahan","year":"1978","unstructured":"Cahan WG, Shah JP, Castro EB. Benign solitary lung lesions in patients with cancer. Ann Surg 1978; 187:241\u20134.","journal-title":"Ann Surg"},{"key":"1_CR15","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1093\/jnci\/90.13.972","volume":"90","author":"PP Leong","year":"1998","unstructured":"Leong PP, Rezai B, Koch WM, et\u00a0al. Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. J Natl Cancer Inst 1998; 90:972\u20137.","journal-title":"J Natl Cancer Inst"},{"key":"1_CR16","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1158\/1078-0432.CCR-05-0257","volume":"11","author":"TW Geurts","year":"2005","unstructured":"Geurts TW, Nederlof PM, van den Brekel MW, et\u00a0al. Pulmonary squamous cell carcinoma following head and neck squamous cell carcinoma: metastasis or second primary? Clin Cancer Res 2005; 11:6608\u201314.","journal-title":"Clin Cancer Res"},{"key":"1_CR17","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1288\/00005537-198002000-00002","volume":"90","author":"ML Dennington","year":"1980","unstructured":"Dennington ML, Carter DR, Meyers AD. Distant metastases in head and neck epidermoid carcinoma. Laryngoscope 1980; 90:196\u2013201.","journal-title":"Laryngoscope"},{"key":"1_CR18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1001\/archsurg.1986.01400030019001","volume":"121","author":"AT Lefor","year":"1986","unstructured":"Lefor AT, Bredenberg CE, Kellman RM, et\u00a0al. Multiple malignancies of the lung and head and neck. Second primary tumor or metastasis? Arch Surg 1986; 121:265\u201370.","journal-title":"Arch Surg"},{"key":"1_CR19","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1002\/1097-0142(197906)43:6<2202::AID-CNCR2820430607>3.0.CO;2-J","volume":"43","author":"MH Amer","year":"1979","unstructured":"Amer MH, Al Sarraf M, Vaitkevicius VK. Factors that affect response to chemotherapy and survival of patients with advanced head and neck cancer. Cancer 1979; 43:2202\u20136.","journal-title":"Cancer"},{"key":"1_CR20","first-page":"99","volume":"114","author":"AD Turnbull","year":"1972","unstructured":"Turnbull AD, Pool JL, Arthur K, et\u00a0al. The role of radiotherapy and chemotherapy in the surgical management of pulmonary metastases. Am J Roentgenol Radium Ther Nucl Med 1972; 114:99\u2013105.","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"1_CR21","first-page":"311","volume":"21","author":"GP Browman","year":"1994","unstructured":"Browman GP, Cronin L. Standard chemotherapy in squamous cell head and neck cancer: what we have learned from randomized trials. Semin Oncol 1994; 21:311\u20139.","journal-title":"Semin Oncol"},{"key":"1_CR22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/oxfordjournals.annonc.a058910","volume":"5","author":"G Catimel","year":"1994","unstructured":"Catimel G, Vermorken JB, Clavel M, et\u00a0al. A phase II study of gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol 1994; 5:543\u20137.","journal-title":"Ann Oncol"},{"key":"1_CR23","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1200\/JCO.1992.10.2.257","volume":"10","author":"C Jacobs","year":"1992","unstructured":"Jacobs C, Lyman G, Velez-Garcia E, et\u00a0al. A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 1992; 10:257\u201363.","journal-title":"J Clin Oncol"},{"key":"1_CR24","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1200\/JCO.1992.10.8.1245","volume":"10","author":"AA Forastiere","year":"1992","unstructured":"Forastiere AA, Metch B, Schuller DE, et\u00a0al. Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study. J Clin Oncol 1992; 10:1245\u201351.","journal-title":"J Clin Oncol"},{"key":"1_CR25","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/oxfordjournals.annonc.a058906","volume":"5","author":"M Clavel","year":"1994","unstructured":"Clavel M, Vermorken JB, Cognetti F, et\u00a0al. Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head and Neck Cancer Cooperative Group. Ann Oncol 1994; 5:521\u20136.","journal-title":"Ann Oncol"},{"key":"1_CR26","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1056\/NEJM199301213280306","volume":"328","author":"EE Vokes","year":"1993","unstructured":"Vokes EE, Weichselbaum RR, Lippman SM, et\u00a0al. Head and neck cancer. N Engl J Med 1993; 328:184\u201394.","journal-title":"N Engl J Med"},{"key":"1_CR27","first-page":"479","volume":"134","author":"LB Choksi","year":"1972","unstructured":"Choksi LB, Takita H, Vincent RG. The surgical management of solitary pulmonary metastasis. Surg Gynecol Obstet 1972; 134:479\u201382.","journal-title":"Surg Gynecol Obstet"},{"key":"1_CR28","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0003-4975(10)63771-X","volume":"28","author":"PM McCormack","year":"1979","unstructured":"McCormack PM, Martini N. The changing role of surgery for pulmonary metastases. Ann Thorac Surg 1979; 28:139\u201345.","journal-title":"Ann Thorac Surg"},{"key":"1_CR29","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1097\/01243894-200611000-00007","volume":"1","author":"JP Griffin","year":"2006","unstructured":"Griffin JP, Eastridge CE, Tolley EA, et\u00a0al. Wedge resection for non\u2013small cell lung cancer in patients with pulmonary insufficiency: prospective ten-year survival. J Thorac Oncol 2006; 1:960\u20134.","journal-title":"J Thorac Oncol"},{"key":"1_CR30","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-0347(199607\/08)18:4<311::AID-HED1>3.0.CO;2-0","volume":"18","author":"J Wedman","year":"1996","unstructured":"Wedman J, Balm AJ, Hart AA, et\u00a0al. Value of resection of pulmonary metastases in head and neck cancer patients. Head Neck 1996; 18:311\u20136.","journal-title":"Head Neck"},{"key":"1_CR31","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/s10434-999-0572-8","volume":"6","author":"D Liu","year":"1999","unstructured":"Liu D, Labow DM, Dang N, et\u00a0al. Pulmonary metastasectomy for head and neck cancers. Ann Surg Oncol 1999; 6:572\u20138.","journal-title":"Ann Surg Oncol"},{"key":"1_CR32","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S1010-7940(02)00119-7","volume":"21","author":"S Margaritora","year":"2002","unstructured":"Margaritora S, Porziella V, D\u2019Andrilli A, et\u00a0al. Pulmonary metastases: can accurate radiological evaluation avoid thoracotomic approach? Eur J Cardiothorac Surg 2002; 21:1111\u20134.","journal-title":"Eur J Cardiothorac Surg"},{"key":"1_CR33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2214\/ajr.172.2.9930781","volume":"172","author":"S Diederich","year":"1999","unstructured":"Diederich S, Semik M, Lentschig MG, et\u00a0al. Helical CT of pulmonary nodules in patients with extrathoracic malignancy: CT-surgical correlation. AJR Am J Roentgenol 1999; 172:353\u201360.","journal-title":"AJR Am J Roentgenol"},{"key":"1_CR34","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1001\/archotol.1994.01880310027006","volume":"120","author":"KH Kim","year":"1994","unstructured":"Kim KH, Sung MW, Chung PS, et\u00a0al. Adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1994; 120:721\u20136.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"1_CR35","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0003-4975(10)62280-1","volume":"38","author":"CF Mountain","year":"1984","unstructured":"Mountain CF, McMurtrey MJ, Hermes KE. Surgery for pulmonary metastasis: a 20-year experience. Ann Thorac Surg 1984; 38:323\u201330.","journal-title":"Ann Thorac Surg"},{"key":"1_CR36","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/1097-0142(197803)41:3<833::AID-CNCR2820410309>3.0.CO;2-4","volume":"41","author":"CF Mountain","year":"1978","unstructured":"Mountain CF, Khalil KG, Hermes KE, et\u00a0al. The contribution of surgery to the management of carcinomatous pulmonary metastases. Cancer 1978; 41:833\u201340.","journal-title":"Cancer"},{"key":"1_CR37","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1002\/1097-0142(19800615)45:12<2981::AID-CNCR2820451216>3.0.CO;2-N","volume":"45","author":"CE Morrow","year":"1980","unstructured":"Morrow CE, Vassilopoulos PP, Grage TB. Surgical resection for metastatic neoplasms of the lung: experience at the University of Minnesota Hospitals. Cancer 1980; 45:2981\u20135.","journal-title":"Cancer"},{"key":"1_CR38","first-page":"102","volume":"25","author":"GA Patterson","year":"1982","unstructured":"Patterson GA, Todd TR, Ilves R, et\u00a0al. Surgical management of pulmonary metastases. Can J Surg 1982; 25:102\u20135.","journal-title":"Can J Surg"},{"key":"1_CR39","first-page":"468","volume":"7","author":"WJ Temple","year":"1980","unstructured":"Temple WJ, Ketcham AS. Surgical management of isolated systemic metastases. Semin Oncol 1980; 7:468\u201380.","journal-title":"Semin Oncol"},{"key":"1_CR40","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/S0003-4975(03)01200-1","volume":"77","author":"S Ercan","year":"2004","unstructured":"Ercan S, Nichols FC III, Trastek VF, et\u00a0al. Prognostic significance of lymph node metastasis found during pulmonary metastasectomy for extrapulmonary carcinoma. Ann Thorac Surg 2004; 77:1786\u201391.","journal-title":"Ann Thorac Surg"},{"key":"1_CR41","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.athoracsur.2005.08.049","volume":"81","author":"J Pfannschmidt","year":"2006","unstructured":"Pfannschmidt J, Klode J, Muley T, et\u00a0al. Nodal involvement at the time of pulmonary metastasectomy: experiences in 245 patients. Ann Thorac Surg 2006; 81:448\u201354.","journal-title":"Ann Thorac Surg"},{"key":"1_CR42","first-page":"453","volume":"5","author":"M Kamiyoshihara","year":"1998","unstructured":"Kamiyoshihara M, Hirai T, Kawashima O, et\u00a0al. The surgical treatment of metastatic tumors in the lung: is lobectomy with mediastinal lymph node dissection suitable treatment? Oncol Rep 1998; 5:453\u20137.","journal-title":"Oncol Rep"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-008-0001-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1245\/s10434-008-0001-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-008-0001-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T04:30:52Z","timestamp":1588825852000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1245\/s10434-008-0001-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,22]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["1"],"URL":"https:\/\/doi.org\/10.1245\/s10434-008-0001-4","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,22]]}}}