{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T17:18:13Z","timestamp":1780766293612,"version":"3.54.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,2,13]],"date-time":"2014-02-13T00:00:00Z","timestamp":1392249600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1245\/s10434-014-3540-x","type":"journal-article","created":{"date-parts":[[2014,2,12]],"date-time":"2014-02-12T16:05:06Z","timestamp":1392221106000},"page":"2083-2090","source":"Crossref","is-referenced-by-count":22,"title":["Pretreatment Clinical Mediastinal Nodal Bulk and Extent do not Influence Survival in N2-Positive Stage IIIA Non-small Cell Lung Cancer Patients Treated with Trimodality Therapy"],"prefix":"10.1245","volume":"21","author":[{"given":"Hyebin","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Chan","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongryull","family":"Pyo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BoKyong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongryul","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heerim","family":"Nam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Mu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Seok","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung-Ju","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keunchil","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Soo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhingook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Ill","family":"Zo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Mog","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,2,13]]},"reference":[{"key":"3540_CR1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00000658-198309000-00015","volume":"198","author":"N Martini","year":"1983","unstructured":"Martini N, Flehinger BJ, Zaman MB, Beattie EJ Jr. Results of resection in non-oat cell carcinoma of the lung with mediastinal lymph node metastases. Ann Surg. 1983;198:386\u2013397.","journal-title":"Ann Surg."},{"key":"3540_CR2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/jnci\/86.9.673","volume":"86","author":"JA Roth","year":"1994","unstructured":"Roth JA, Fossella F, Komaki R, et al. A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. J Natl Cancer Inst. 1994;86:673\u2013680.","journal-title":"J Natl Cancer Inst."},{"key":"3540_CR3","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1056\/NEJM199010043231403","volume":"323","author":"RO Dillman","year":"1990","unstructured":"Dillman RO, Seagren SL, Propert KJ, et al. A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer. N Engl J Med. 1990;323:940\u2013945.","journal-title":"N Engl J Med."},{"key":"3540_CR4","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1002\/1097-0142(19870601)59:11<1874::AID-CNCR2820591106>3.0.CO;2-Z","volume":"59","author":"CA Perez","year":"1987","unstructured":"Perez CA, Pajak TF, Rubin P, et al. Long-term observations of the patterns of failure in patients with unresectable non-oat cell carcinoma of the lung treated with definitive radiotherapy. Report by the Radiation Therapy Oncology Group. Cancer. 1987;59:1874\u20131881.","journal-title":"Cancer."},{"key":"3540_CR5","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S1055-3207(18)30303-X","volume":"6","author":"N Martini","year":"1997","unstructured":"Martini N, Kris MG, Ginsberg RJ. The role of multimodality therapy in locoregional non-small cell lung cancer. Surg Oncol Clin N Am. 1997;6:769\u2013791.","journal-title":"Surg Oncol Clin N Am."},{"key":"3540_CR6","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1093\/jnci\/djr325","volume":"103","author":"WJ Curran Jr","year":"2011","unstructured":"Curran WJ Jr, Paulus R, Langer CJ, et al. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410. J Natl Cancer Inst. 2011;103:1452\u20131460.","journal-title":"J Natl Cancer Inst."},{"key":"3540_CR7","doi-asserted-by":"crossref","first-page":"5910","DOI":"10.1200\/JCO.2005.03.070","volume":"23","author":"P Fournel","year":"2005","unstructured":"Fournel P, Robinet G, Thomas P, et al. Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Etienne d\u2019Oncologie Thoracique-Groupe Francais de Pneumo-Cancerologie NPC 95-01 Study. J Clin Oncol. 2005;23:5910\u20135917.","journal-title":"J Clin Oncol."},{"key":"3540_CR8","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/0003-4975(92)90373-C","volume":"53","author":"HI Pass","year":"1992","unstructured":"Pass HI, Pogrebniak HW, Steinberg SM, et al. Randomized trial of neoadjuvant therapy for lung cancer: interim analysis. Ann Thorac Surg. 1992;53:992\u2013998.","journal-title":"Ann Thorac Surg."},{"key":"3540_CR9","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1200\/JCO.2010.33.7089","volume":"30","author":"GV Scagliotti","year":"2012","unstructured":"Scagliotti GV, Pastorino U, Vansteenkiste JF, et al. Randomized phase III study of surgery alone or surgery plus preoperative cisplatin and gemcitabine in stages IB to IIIA non-small-cell lung cancer. J Clin Oncol. 2012;30:172\u2013178.","journal-title":"J Clin Oncol."},{"key":"3540_CR10","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1200\/JCO.1995.13.8.1880","volume":"13","author":"KS Albain","year":"1995","unstructured":"Albain KS, Rusch VW, Crowley JJ, et al. Concurrent cisplatin\/etoposide plus chest radiotherapy followed by surgery for stages IIIA (N2) and IIIB non-small-cell lung cancer: mature results of Southwest Oncology Group phase II study 8805. J Clin Oncol. 1995;13:1880\u20131892.","journal-title":"J Clin Oncol."},{"key":"3540_CR11","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1200\/JCO.1997.15.2.712","volume":"15","author":"NC Choi","year":"1997","unstructured":"Choi NC, Carey RW, Daly W, et al. Potential impact on survival of improved tumor downstaging and resection rate by preoperative twice-daily radiation and concurrent chemotherapy in stage IIIA non-small-cell lung cancer. J Clin Oncol. 1997;15:712\u2013722.","journal-title":"J Clin Oncol."},{"key":"3540_CR12","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0140-6736(09)60737-6","volume":"374","author":"KS Albain","year":"2009","unstructured":"Albain KS, Swann RS, Rusch VW, et al. Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial. Lancet. 2009;374:379\u2013386.","journal-title":"Lancet."},{"key":"3540_CR13","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.athoracsur.2012.03.018","volume":"93","author":"AA Shah","year":"2012","unstructured":"Shah AA, Berry MF, Tzao C, et al. Induction chemoradiation is not superior to induction chemotherapy alone in stage IIIA lung cancer. Ann Thorac Surg. 2012;93:1807\u20131812.","journal-title":"Ann Thorac Surg."},{"key":"3540_CR14","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1093\/icvts\/ivs412","volume":"15","author":"S Toyooka","year":"2012","unstructured":"Toyooka S, Kiura K, Shien K, et al. Induction chemoradiotherapy is superior to induction chemotherapy for the survival of non-small-cell lung cancer patients with pathological mediastinal lymph node metastasis. Interact Cardiovasc Thorac Surg. 2012;15:954\u2013960.","journal-title":"Interact Cardiovasc Thorac Surg."},{"key":"3540_CR15","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1080\/028418601750444123","volume":"40","author":"YC Ahn","year":"2001","unstructured":"Ahn YC, Park K, Kim DY, et al. Preoperative concurrent chemoradiotherapy for stage IIIA non-small cell lung cancer. Acta Oncol. 2001;40:588\u2013592.","journal-title":"Acta Oncol."},{"key":"3540_CR16","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3346\/jkms.2006.21.2.229","volume":"21","author":"MK Kang","year":"2006","unstructured":"Kang MK, Ahn YC, Lim DH, et al. Preoperative concurrent radiochemotherapy and surgery for stage IIIA non-small cell lung cancer. J Korean Med Sci. 2006;21:229\u2013235.","journal-title":"J Korean Med Sci."},{"key":"3540_CR17","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.lungcan.2006.10.024","volume":"55","author":"KJ Kim","year":"2007","unstructured":"Kim KJ, Ahn YC, Lim do H, et al. (2007) Analyses on prognostic factors following tri-modality therapy for stage IIIa non-small cell lung cancer. Lung Cancer. 55:329\u2013336.","journal-title":"Lung Cancer."},{"key":"3540_CR18","unstructured":"NCCN guidelines version 2. 2013. Non-small cell lung cancer. Available from http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/nscl.pdf . 2013."},{"key":"3540_CR19","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jtcvs.2003.07.027","volume":"127","author":"M Machtay","year":"2004","unstructured":"Machtay M, Lee JH, Stevenson JP, et al. Two commonly used neoadjuvant chemoradiotherapy regimens for locally advanced stage III non-small cell lung carcinoma: long-term results and associations with pathologic response. J Thorac Cardiovasc Surg. 2004;127:108\u2013113.","journal-title":"J Thorac Cardiovasc Surg."},{"key":"3540_CR20","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.ejcts.2008.01.063","volume":"33","author":"N Pourel","year":"2008","unstructured":"Pourel N, Santelmo N, Naafa N, et al. Concurrent cisplatin\/etoposide plus 3D-conformal radiotherapy followed by surgery for stage IIB (superior sulcus T3N0)\/III non-small cell lung cancer yields a high rate of pathological complete response. Eur J Cardiothorac Surg. 2008;33:829\u2013836.","journal-title":"Eur J Cardiothorac Surg."},{"key":"3540_CR21","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1097\/JTO.0b013e3181b9e860","volume":"4","author":"RM D\u2019Angelillo","year":"2009","unstructured":"D\u2019Angelillo RM, Trodella L, Ciresa M, et al. Multimodality treatment of stage III non-small cell lung cancer: analysis of a phase II trial using preoperative cisplatin and gemcitabine with concurrent radiotherapy. J Thorac Oncol. 2009;4:1517\u20131523.","journal-title":"J Thorac Oncol."},{"key":"3540_CR22","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1200\/JCO.2000.18.16.2981","volume":"18","author":"F Andre","year":"2000","unstructured":"Andre F, Grunenwald D, Pignon JP, et al. Survival of patients with resected N2 non-small-cell lung cancer: evidence for a subclassification and implications. J Clin Oncol. 2000;18:2981\u20132989.","journal-title":"J Clin Oncol."},{"key":"3540_CR23","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/JTO.0b013e31823a385f","volume":"7","author":"NT Tanner","year":"2012","unstructured":"Tanner NT, Gomez M, Rainwater C, et al. Physician preferences for management of patients with stage IIIA NSCLC: impact of bulk of nodal disease on therapy selection. J Thorac Oncol. 2012;7:365\u2013369.","journal-title":"J Thorac Oncol."}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-014-3540-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1245\/s10434-014-3540-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-014-3540-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T15:31:53Z","timestamp":1565191913000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1245\/s10434-014-3540-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,13]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["3540"],"URL":"https:\/\/doi.org\/10.1245\/s10434-014-3540-x","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,13]]}}}