{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T20:33:55Z","timestamp":1785357235257,"version":"3.55.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"13","license":[{"start":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T00:00:00Z","timestamp":1470182400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1245\/s10434-016-5451-5","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T16:07:57Z","timestamp":1470240477000},"page":"4302-4309","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Long-Term Outcome of Rectal Cancer With Clinically (EUS\/MRI) Metastatic Mesorectal Lymph Nodes Treated by Neoadjuvant Chemoradiation: Role of Organ Preservation Strategies in Relation to Pathologic Response"],"prefix":"10.1245","volume":"23","author":[{"given":"Claudio","family":"Belluco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Forlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Olivieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Cannizzaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Canzonieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Buonadonna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ettore","family":"Bidoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Matrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Bertola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"De Paoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,8,3]]},"reference":[{"key":"5451_CR1","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1056\/NEJMoa040694","volume":"351","author":"R Sauer","year":"2004","unstructured":"Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 2004;351:1731\u201340.","journal-title":"N Engl J Med."},{"key":"5451_CR2","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1056\/NEJMoa060829","volume":"355","author":"J-F Bosset","year":"2006","unstructured":"Bosset J-F, Collette L, Calais G, et al. Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med. 2006;355:1114\u201323.","journal-title":"N Engl J Med."},{"key":"5451_CR3","doi-asserted-by":"publisher","first-page":"4169","DOI":"10.1245\/s10434-013-3198-9","volume":"20","author":"NN Rahbari","year":"2013","unstructured":"Rahbari NN, Elbers H, Askoxylakis V, et al. Neoadjuvant radiotherapy for rectal cancer: meta-analysis of randomized controlled trials. Ann Surg Oncol. 2013;20:4169\u201382. doi: 10.1245\/s10434-013-3198-9 .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR4","unstructured":"NCCN Clinical Practice Guidelines in Oncology. Rectal cancer (version 1.2016). http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/rectal.pdf . Accessed 23 Feb 2016."},{"key":"5451_CR5","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.clon.2007.11.013","volume":"20","author":"P Sanghera","year":"2008","unstructured":"Sanghera P, Wong DW, McConkey CC, Geh JI, Hartley A. Chemoradiotherapy for rectal cancer: an updated analysis of factors affecting pathological response. Clin Oncol R Coll Radiol. 2008;20:176\u201383. doi: 10.1016\/j.clon.2007.11.013 .","journal-title":"Clin Oncol R Coll Radiol."},{"key":"5451_CR6","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1200\/JCO.2013.54.3769","volume":"32","author":"E Fokas","year":"2014","unstructured":"Fokas E, Liersch T, Fietkau R, et al. Tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: updated results of the CAO\/ARO\/AIO-94 trial. J Clin Oncol. 2014;32:1554\u201362. doi: 10.1200\/JCO.2013.54.3769 .","journal-title":"J Clin Oncol."},{"key":"5451_CR7","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.1200\/JCO.2011.39.7901","volume":"30","author":"IJ Park","year":"2012","unstructured":"Park IJ, You YN, Agarwal A, et al. Neoadjuvant treatment response as an early response indicator for patients with rectal cancer. J Clin Oncol. 2012;30:1770\u20136. doi: 10.1200\/JCO.2011.39.7901 .","journal-title":"J Clin Oncol."},{"key":"5451_CR8","doi-asserted-by":"publisher","first-page":"3686","DOI":"10.1245\/s10434-011-1822-0","volume":"18","author":"C Belluco","year":"2011","unstructured":"Belluco C, De Paoli A, Canzonieri V, et al. Long-term outcome of patients with complete pathological response after neoadjuvant chemoradiation for cT3 rectal cancer: implications for local excision surgical strategies. Ann Surg Oncol. 2011;18:3686\u201393. doi: 10.1245\/s10434-011-1822-0 .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR9","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1470-2045(10)70172-8","volume":"11","author":"M Maas","year":"2010","unstructured":"Maas M, Nelemans PJ, Valentini V, et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol. 2010;11:835\u201344.","journal-title":"Lancet Oncol."},{"key":"5451_CR10","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1245\/s10434-009-0735-7","volume":"17","author":"GG Callender","year":"2010","unstructured":"Callender GG, Das P, Rodriguez-Bigas MA, et al. Local excision after preoperative chemoradiation results in an equivalent outcome to total mesorectal excision in selected patients with T3 rectal cancer. Ann Surg Oncol. 2010;17:441\u20137. doi: 10.1245\/s10434-009-0735-7 .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR11","doi-asserted-by":"publisher","first-page":"2030","DOI":"10.1007\/s00464-008-9976-y","volume":"22","author":"M Guerrieri","year":"2008","unstructured":"Guerrieri M, Baldarelli M, Organetti L, Grillo Ruggeri F, Mantello G, Bartolacci S, et al. Transanal endoscopic microsurgery for the treatment of selected patients with distal rectal cancer: 15\u00a0years experience. Surg Endosc. 2008;22:2030\u20135. doi: 10.1007\/s00464-008-9976-y .","journal-title":"Surg Endosc."},{"key":"5451_CR12","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1007\/s11605-008-0647-z","volume":"12","author":"RM Nair","year":"2008","unstructured":"Nair RM, Siegel EM, Chen DT, et al. Long-term results of transanal excision after neoadjuvant chemoradiation for T2 and T3 adenocarcinomas of the rectum. J Gastrointest Surg. 2008;12:1797\u2013805. doi: 10.1007\/s11605-008-0647-z .","journal-title":"J Gastrointest Surg."},{"key":"5451_CR13","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1245\/s10434-007-9732-x","volume":"15","author":"T Borschitz","year":"2008","unstructured":"Borschitz T, Wachtlin D, M\u00f6hler M, Schmidberger H, Junginger T. Neoadjuvant chemoradiation and local excision for T2\u20133 rectal cancer. Ann Surg Oncol. 2008;15:712\u201320. doi: 10.1245\/s10434-007-9732-x .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR14","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1016\/j.ijrobp.2004.07.368","volume":"60","author":"M Bonnen","year":"2004","unstructured":"Bonnen M, Crane C, Vauthey JN, et al. Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients. Int J Radiat Oncol Biol Phys. 2004;60:1098\u2013105. doi: 10.1016\/j.ijrobp.2004.07.368 .","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"5451_CR15","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1007\/s003840100327","volume":"17","author":"L Ruo","year":"2002","unstructured":"Ruo L, Guillem JG, Minsky BD, Quan SH, Paty PB, Cohen AM. Preoperative radiation with or without chemotherapy and full-thickness transanal excision for selected T2 and T3 distal rectal cancers. Int J Colorectal Dis. 2002;17:54\u20138. doi: 10.1007\/s003840100327 .","journal-title":"Int J Colorectal Dis."},{"key":"5451_CR16","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1097\/00000658-200109000-00009","volume":"234","author":"CJ Kim","year":"2001","unstructured":"Kim CJ, Yeatman TJ, Coppola D, et al. Local excision of T2 and T3 rectal cancers after downstaging chemoradiation. Ann Surg. 2001;234:352\u20138. doi: 10.1097\/00000658-200109000-00009 .","journal-title":"Ann Surg."},{"key":"5451_CR17","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/S1072-7515(02)01128-6","volume":"194","author":"SR Schell","year":"2002","unstructured":"Schell SR, Zlotecki RA, Mendenhall WM, Marsh RW, Vauthey JN, Copeland EM III. Transanal excision of locally advanced rectal cancers downstaged using neoadjuvant chemoradiotherapy. J Am Coll Surg. 2002;194:584\u201390. doi: 10.1016\/S1072-7515(02)01128-6 .","journal-title":"J Am Coll Surg."},{"key":"5451_CR18","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1097\/DCR.0b013e3182a2303e","volume":"56","author":"S Pucciarelli","year":"2013","unstructured":"Pucciarelli S, De Paoli A, Guerrieri M, et al. Local excision after preoperative chemoradiotherapy for rectal cancer: results of a multicenter phase II clinical trial. Dis Colon Rectum. 2013;56:1349\u201356.","journal-title":"Dis Colon Rectum."},{"key":"5451_CR19","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.ijrobp.2013.12.012","volume":"88","author":"A Habr-Gama","year":"2014","unstructured":"Habr-Gama A, Gama-Rodrigues J, Sao Juliao GP, et al. Local recurrence after complete clinical response and watch and wait in rectal cancer after neoadjuvant chemoradiation: impact of salvage therapy on local disease control. Int J Radiat Oncol Biol Phys. 2014;88:822\u20138.","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"5451_CR20","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1200\/JCO.2011.37.7176","volume":"29","author":"M Maas","year":"2011","unstructured":"Maas M, Beets-Tan RG, Lambregts DM, et al. Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer. J Clin Oncol. 2011;29:4633\u201340.","journal-title":"J Clin Oncol."},{"key":"5451_CR21","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S1470-2045(15)00120-5","volume":"16","author":"AL Appelt","year":"2015","unstructured":"Appelt AL, Ploen J, Harling H, et al. High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study. Lancet Oncol. 2015;16:919\u201327.","journal-title":"Lancet Oncol."},{"key":"5451_CR22","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1097\/SLA.0b013e3182759f1c","volume":"256","author":"JD Smith","year":"2012","unstructured":"Smith JD, Ruby JA, Goodman KA, et al. Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy. Ann Surg. 2012;256:965\u201372.","journal-title":"Ann Surg."},{"key":"5451_CR23","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00384-015-2165-2","volume":"30","author":"RK Smith","year":"2015","unstructured":"Smith RK, Fry RD, Mahmoud NN, Paulson EC. Surveillance after neoadjuvant therapy in advanced rectal cancer with complete clinical response can have comparable outcomes to total mesorectal excision. Int J Colorectal Dis. 2015;30:769\u201374.","journal-title":"Int J Colorectal Dis."},{"key":"5451_CR24","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s10350-004-0535-x","volume":"47","author":"TE Read","year":"2004","unstructured":"Read TE, Andujar JE, Caushaj PF, et al. Neoadjuvant therapy for rectal cancer: histologic response of the primary tumor predicts nodal status. Dis Colon Rectum. 2004;47:825\u201331.","journal-title":"Dis Colon Rectum."},{"key":"5451_CR25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1245\/ASO.2005.03.044","volume":"12","author":"S Pucciarelli","year":"2005","unstructured":"Pucciarelli S, Capirci C, Emanuele U, et al. Relationship between pathological T-stage and nodal metastasis after preoperative chemoradiotherapy for locally advanced rectal cancer. Ann Surg Oncol. 2005;12:111\u20136.","journal-title":"Ann Surg Oncol."},{"key":"5451_CR26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00384-005-0749-y","volume":"21","author":"R Hughes","year":"2006","unstructured":"Hughes R, Glynne-Jones R, Grainger J, et al. Can pathological complete response in the primary tumour following pre-operative pelvic chemoradiotherapy for T3\u2013T4 rectal cancer predict for sterilisation of pelvic lymph nodes, a low risk of local recurrence and the appropriateness of local excision?. Int J Colorectal Dis. 2006;21:11\u20137.","journal-title":"Int J Colorectal Dis."},{"key":"5451_CR27","doi-asserted-by":"publisher","first-page":"3481","DOI":"10.1200\/JCO.2007.15.6646","volume":"26","author":"JG Guillem","year":"2008","unstructured":"Guillem JG, Minsky BD. Extended perineal resection of distal rectal cancers: surgical advance, increased utilization of neoadjuvant therapies, proper patient selection or all of the above?. J Clin Oncol. 2008;26:3481\u20132. doi: 10.1200\/JCO.2007.15.6646 .","journal-title":"J Clin Oncol."},{"key":"5451_CR28","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1111\/j.1463-1318.2008.01597.x","volume":"11","author":"M Berho","year":"2009","unstructured":"Berho M, Oviedo M, Stone E, et al. The correlation between tumour regression grade and lymph node status after chemoradiation in rectal cancer. Colorectal Dis. 2009;11:254\u20138. doi: 10.1111\/j.1463-1318.2008.01597.x . Epub 29 May 2008.","journal-title":"Colorectal Dis."},{"key":"5451_CR29","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1097\/SLA.0b013e3181f3f1b1","volume":"252","author":"SG Yeo","year":"2010","unstructured":"Yeo SG, Kim DY, Kim TH, et al. Pathological complete response of primary tumor following preoperative chemoradiotherapy for locally advanced rectal cancer: long-term outcomes and prognostic significance of pathological nodal status (KROG 09-01). Ann Surg. 2010;252:998\u20131004. doi: 10.1097\/SLA.0b013e3181f3f1b1 . PubMed PMID: 21107110.","journal-title":"Ann Surg."},{"key":"5451_CR30","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1097\/DCR.0b013e3182644334","volume":"55","author":"TY Jang","year":"2012","unstructured":"Jang TY, Yu CS, Yoon YS, et al. Oncologic outcome after preoperative chemoradiotherapy in patients with pathological T0 (ypT0) rectal cancer. Dis Colon Rectum. 2012;55:1024\u201331. doi: 10.1097\/DCR.0b013e3182644334 .","journal-title":"Dis Colon Rectum."},{"key":"5451_CR31","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1245\/s10434-012-2773-9","volume":"20","author":"H Tranchart","year":"2013","unstructured":"Tranchart H, Lef\u00e8vre JH, Svrcek M, Flejou JF, Tiret E, Parc Y. What is the incidence of metastatic lymph node involvement after significant pathological response of primary tumor following neoadjuvant treatment for locally advanced rectal cancer?. Ann Surg Oncol. 2013;20:1551\u20139. doi: 10.1245\/s10434-012-2773-9 .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR32","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1097\/DCR.0b013e318278ff8a","volume":"56","author":"IJ Park","year":"2013","unstructured":"Park IJ, You YN, Skibber JM, Rodriguez-Bigas MA, Feig B, Nguyen S, et al. Comparative analysis of lymph node metastases in patients with ypT0-2 rectal cancers after neoadjuvant chemoradiotherapy. Dis Colon Rectum. 2013;56:135\u201341. doi: 10.1097\/DCR.0b013e318278ff8a .","journal-title":"Dis Colon Rectum."},{"key":"5451_CR33","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/DCR.0000000000000570","volume":"59","author":"T Sprenger","year":"2016","unstructured":"Sprenger T, Rothe H, Conradi LC, et al. Stage-dependent frequency of lymph node metastases in patients with rectal carcinoma after preoperative chemoradiation: results from the CAO\/ARO\/AIO-94 Trial and from a comparative prospective evaluation with extensive pathological workup. Dis Colon Rectum. 2016;59:377\u201385.","journal-title":"Dis Colon Rectum."},{"key":"5451_CR34","first-page":"978","volume":"61","author":"YL Zhao","year":"2014","unstructured":"Zhao YL, Cao DM, Zhou QC, Yang N, Yao HL. Accuracy of endorectal endoscopic ultrasound (EUS) for locally advanced rectal cancer (LARC) restaging after neoadjuvant chemoradiotherapy (NAT): a meta-analysis (review). Hepatogastroenterology. 2014;61:978\u201383.","journal-title":"Hepatogastroenterology."},{"key":"5451_CR35","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1111\/codi.12976","volume":"17","author":"S Memon","year":"2015","unstructured":"Memon S, Lynch AC, Bressel M, Wise AG, Heriot AG. Systematic review and meta-analysis of the accuracy of MRI and endorectal ultrasound in the restaging and response assessment of rectal cancer following neoadjuvant therapy. Colorectal Dis. 2015;17:748\u201361. doi: 10.1111\/codi.12976 .","journal-title":"Colorectal Dis."},{"key":"5451_CR36","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1038\/bjc.2014.256","volume":"111","author":"E Jwa","year":"2014","unstructured":"Jwa E, Kim JH, Han S, et al. Nomogram to predict ypN status after chemoradiation in patients with locally advanced rectal cancer. Br J Cancer. 2014;111:249\u201354. doi: 10.1038\/bjc.2014.256 .","journal-title":"Br J Cancer."},{"key":"5451_CR37","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1002\/1097-0142(19940601)73:11<2680::AID-CNCR2820731105>3.0.CO;2-C","volume":"73","author":"AM Mandard","year":"1994","unstructured":"Mandard AM, Dalibard F, Mandard JC, et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma: clinicopathologic correlations. Cancer. 1994;73:2680\u20136.","journal-title":"Cancer."},{"key":"5451_CR38","volume-title":"AJCC\u2014Cancer Staging Manual","author":"SB Edge","year":"2010","unstructured":"Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A III. AJCC\u2014Cancer Staging Manual. 7th ed. Springer, New York, 2010.","edition":"7"},{"key":"5451_CR39","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","volume":"53","author":"EL Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457\u201381.","journal-title":"J Am Stat Assoc."},{"key":"5451_CR40","first-page":"178","volume":"34","author":"DR Cox","year":"1972","unstructured":"Cox DR. Regression model and life tables. J R Stat Soc B. 1972;34:178\u2013220.","journal-title":"J R Stat Soc B."},{"key":"5451_CR41","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.1245\/s10434-011-2209-y","volume":"19","author":"L Zorcolo","year":"2012","unstructured":"Zorcolo L, Rosman AS, Restivo A, Pisano M, Nigri GR, Fancellu A, et al. Complete pathological response after combined modality treatment for rectal cancer and long-term survival: a meta-analysis. Ann Surg Oncol. 2012;19:2822\u201332. doi: 10.1245\/s10434-011-2209-y .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR42","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/codi.13072","volume":"18","author":"HH Wasmuth","year":"2016","unstructured":"Wasmuth HH, Rekstad LC, Tran\u00f8 G. The outcome and the frequency of pathological complete response after neoadjuvant radiotherapy in curative resections for advanced rectal cancer: a population-based study. Colorectal Dis. 2016;18:67\u201372. doi: 10.1111\/codi.13072 .","journal-title":"Colorectal Dis."},{"key":"5451_CR43","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/S1470-2045(15)00215-6","volume":"16","author":"J Garcia-Aguilar","year":"2015","unstructured":"Garcia-Aguilar J, Renfro LA, Chow OS, et al. Organ preservation for clinical T2N0 distal rectal cancer using neoadjuvant chemoradiotherapy and local excision (ACOSOG Z6041): results of an open-label, single-arm, multi-institutional, phase 2 trial. Lancet Oncol. 2015;16:1537\u201346. doi: 10.1016\/S1470-2045(15)00215-6 .","journal-title":"Lancet Oncol."},{"issue":"Suppl 3","key":"5451_CR44","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1463-1318.2006.01066.x","volume":"8","author":"A Habr-Gama","year":"2006","unstructured":"Habr-Gama A. Assessment and management of the complete clinical response of rectal cancer to chemoradiotherapy. Colorectal Dis. 2006;8(Suppl 3):21\u20134.","journal-title":"Colorectal Dis."},{"key":"5451_CR45","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1097\/SLA.0b013e31820b01f1","volume":"253","author":"DM Lambregts","year":"2011","unstructured":"Lambregts DM, Beets GL, Maas M, et al. Accuracy of gadofosveset-enhanced MRI for nodal staging and restaging in rectal cancer. Ann Surg. 2011;253:539\u201345. doi: 10.1097\/SLA.0b013e31820b01f1 .","journal-title":"Ann Surg."},{"key":"5451_CR46","doi-asserted-by":"publisher","first-page":"3598","DOI":"10.1245\/s10434-014-3753-z","volume":"21","author":"S Memon","year":"2014","unstructured":"Memon S, Lynch AC, Akhurst T, Ngan SY, Warrier SK, Michael M, et al. Systematic review of FDG-PET prediction of complete pathological response and survival in rectal cancer. Ann Surg Oncol. 2014;21:3598\u2013607. doi: 10.1245\/s10434-014-3753-z .","journal-title":"Ann Surg Oncol."},{"key":"5451_CR47","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.ijrobp.2015.09.008","volume":"93","author":"MH Martens","year":"2015","unstructured":"Martens MH, van Heeswijk MM, van den Broek JJ, et al. Prospective, multicenter validation study of magnetic resonance volumetry for response assessment after preoperative chemoradiation in rectal cancer: can the results in the literature be reproduced? Int J Radiat Oncol Biol Phys. 2015;93:1005\u201314. doi: 10.1016\/j.ijrobp.2015.09.008 .","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"5451_CR48","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1097\/DCR.0000000000000557","volume":"59","author":"DA Schneider","year":"2016","unstructured":"Schneider DA, Akhurst TJ, Ngan SY, et al. Relative value of restaging MRI, CT, and FDG-PET scan after preoperative chemoradiation for rectal cancer. Dis Colon Rectum. 2016;59:179\u201386. doi: 10.1097\/DCR.0000000000000557 .","journal-title":"Dis Colon Rectum."}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-016-5451-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1245\/s10434-016-5451-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-016-5451-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T19:52:45Z","timestamp":1498333965000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1245\/s10434-016-5451-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,3]]},"references-count":48,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["5451"],"URL":"https:\/\/doi.org\/10.1245\/s10434-016-5451-5","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,3]]}}}