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Nobuaki Sato has received honoraria from Chugai, Eisai, Taiho and Pfizer, and has received reimbursement from Sysmex for travel, accommodation, and expenses. Takashi Ishikawa has received honoraria from Taiho. Seigo Nakamura has received honoraria from AstraZeneca, Pfizer, Chugai, and Taiho. Takayuki Kinoshita has received honoraria from AstraZeneca, Chugai, Vital, Tsumura, Takeda, Eisai, Hamamatsu Photonics, Covidien and Sysmex. Futoshi Akiyama has had a consulting or advisory role for Sysmex. Shinzaburo Noguchi has received honoraria from AstraZeneca, Novartis, Pfizer, Sysmex, Chugai, Nippon Kayaku, Takeda, and Ono; has had consulting or advisory roles for AstraZeneca, Novartis, and Taiho; has received research funding to the institution from AstraZeneca, Novartis, Pfizer, Chugai, Takeda, Sysmex, Daiichi-Sankyo, Kyowa-Kirin, Nippon Kayaku, Eisai, and Ono; and has held joint patents with Sysmex on items not related to this study. Akiko Ogiya, Yoshiaki Sota, Daisuke Yotsumoto, Hitoshi Tsuda, and Yasuyo Ohi declare no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}