{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:14:59Z","timestamp":1784121299571,"version":"3.55.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T00:00:00Z","timestamp":1620518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T00:00:00Z","timestamp":1620518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1245\/s10434-021-10092-0","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T21:02:24Z","timestamp":1620594144000},"page":"7742-7758","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Minimally Invasive Versus Open Pancreatectomy for Right-Sided and Left-Sided G1\/G2 Nonfunctioning Pancreatic Neuroendocrine Tumors: A Multicenter Matched Analysis with an Inverse Probability of Treatment-Weighting Method"],"prefix":"10.1245","volume":"28","author":[{"given":"Ho Kyoung","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Byung","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minsu","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wooil","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Young","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Seok","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Wook","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Moo","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon Seong","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Ho","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chol Kyoon","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keun Soo","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huisong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Eun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Young","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Hoon","family":"Roh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Joon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Wook","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song Cheol","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Seong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoo-Seok","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Korean Pancreas Surgery Club","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Seok","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-Whe","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Jung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Woong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Sup","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koo Jeong","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seog Ki","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon Kook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Chan","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,9]]},"reference":[{"key":"10092_CR1","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1677\/ERC-07-0221","volume":"15","author":"TR Halfdanarson","year":"2008","unstructured":"Halfdanarson TR, Rubin J, Farnell MB, Grant CS, Petersen GM. Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors. Endocr Relat Cancer. 2008;15:409\u201327.","journal-title":"Endocr Relat Cancer."},{"key":"10092_CR2","doi-asserted-by":"publisher","first-page":"9512","DOI":"10.3748\/wjg.v21.i32.9512","volume":"21","author":"JM Cloyd","year":"2015","unstructured":"Cloyd JM, Poultsides GA. Non-functional neuroendocrine tumors of the pancreas: advances in diagnosis and management. World J Gastroenterol. 2015;21:9512\u201325.","journal-title":"World J Gastroenterol."},{"key":"10092_CR3","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1038\/nrclinonc.2009.82","volume":"6","author":"V Fendrich","year":"2009","unstructured":"Fendrich V, Waldmann J, Bartsch DK, Langer P. Surgical management of pancreatic endocrine tumors. Nat Rev Clin Oncol. 2009;6:419\u201328.","journal-title":"Nat Rev Clin Oncol."},{"key":"10092_CR4","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/hpb.12162","volume":"16","author":"P Drymousis","year":"2014","unstructured":"Drymousis P, Raptis DA, Spalding D, et al. Laparoscopic versus open pancreas resection for pancreatic neuroendocrine tumours: a systematic review and meta-analysis. HPB Oxf. 2014;16:397\u2013406.","journal-title":"HPB Oxf."},{"key":"10092_CR5","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s00464-017-5702-y","volume":"32","author":"SH Han","year":"2018","unstructured":"Han SH, Han IW, Heo JS, et al. Laparoscopic versus open distal pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors: a large single-center study. Surg Endosc. 2018;32:443\u20139.","journal-title":"Surg Endosc."},{"key":"10092_CR6","doi-asserted-by":"publisher","first-page":"4177","DOI":"10.1007\/s00464-019-06969-7","volume":"33","author":"H Kim","year":"2019","unstructured":"Kim H, Song KB, Hwang DW, Lee JH, Alshammary S, Kim SC. Laparoscopic versus open pancreaticoduodenectomy for pancreatic neuroendocrine tumors: a single-center experience. Surg Endosc. 2019;33:4177\u201385.","journal-title":"Surg Endosc."},{"key":"10092_CR7","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1080\/17474124.2017.1253473","volume":"11","author":"D Tamburrino","year":"2017","unstructured":"Tamburrino D, Partelli S, Renzi C, et al. Systematic review and meta-analysis on laparoscopic pancreatic resections for neuroendocrine neoplasms (PNENs). Expert Rev Gastroenterol Hepatol. 2017;11:65\u201373.","journal-title":"Expert Rev Gastroenterol Hepatol."},{"key":"10092_CR8","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1002\/bjs.10220","volume":"103","author":"F Tian","year":"2016","unstructured":"Tian F, Hong XF, Wu WM, et al. Propensity score-matched analysis of robotic versus open surgical enucleation for small pancreatic neuroendocrine tumours. Br J Surg. 2016;103:1358\u201364.","journal-title":"Br J Surg."},{"key":"10092_CR9","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","volume":"240","author":"D Dindo","year":"2004","unstructured":"Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205\u201313.","journal-title":"Ann Surg."},{"key":"10092_CR10","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.surg.2005.05.001","volume":"138","author":"C Bassi","year":"2005","unstructured":"Bassi C, Dervenis C, Butturini G, et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery. 2005;138:8\u201313.","journal-title":"Surgery."},{"key":"10092_CR11","unstructured":"Bosman F, Hruban R, Theise N. WHO classification of tumours of the digestive system, 4th ed. International Agency for Research on Cancer, Lyon, 2010."},{"key":"10092_CR12","doi-asserted-by":"publisher","first-page":"3687","DOI":"10.1245\/s10434-012-2416-1","volume":"19","author":"JH Shim","year":"2012","unstructured":"Shim JH, Yoon DL, Han S, et al. Is serum alpha-fetoprotein useful for predicting recurrence and mortality specific to hepatocellular carcinoma after hepatectomy? A test based on propensity scores and competing risks analysis. Ann Surg Oncol. 2012;19:3687\u201396.","journal-title":"Ann Surg Oncol."},{"key":"10092_CR13","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s12874-015-0017-y","volume":"15","author":"AS Vaughan","year":"2015","unstructured":"Vaughan AS, Kelley CF, Luisi N, del Rio C, Sullivan PS, Rosenberg ES. An application of propensity score-weighting to quantify the causal effect of rectal sexually transmitted infections on incident HIV among men who have sex with men. BMC Med Res Methodol. 2015;15:25.","journal-title":"BMC Med Res Methodol."},{"key":"10092_CR14","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.jacc.2016.10.060","volume":"69","author":"MC Elze","year":"2017","unstructured":"Elze MC, Gregson J, Baber U, et al. Comparison of propensity score methods and covariate adjustment: evaluation in 4 cardiovascular studies. J Am Coll Cardiol. 2017;69:345\u201357.","journal-title":"J Am Coll Cardiol."},{"key":"10092_CR15","doi-asserted-by":"publisher","first-page":"2543","DOI":"10.1001\/jama.1982.03320430047030","volume":"247","author":"FE Harrell Jr","year":"1982","unstructured":"Harrell FE Jr, Califf RM, Pryor DB, Lee KL, Rosati RA. Evaluating the yield of medical tests. JAMA. 1982;247:2543\u20136.","journal-title":"JAMA."},{"key":"10092_CR16","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1111\/j.0006-341X.2005.030814.x","volume":"61","author":"PJ Heagerty","year":"2005","unstructured":"Heagerty PJ, Zheng Y. Survival model predictive accuracy and ROC curves. Biometrics. 2005;61:92\u2013105.","journal-title":"Biometrics."},{"key":"10092_CR17","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.surg.2015.05.042","volume":"159","author":"XM Keutgen","year":"2016","unstructured":"Keutgen XM, Nilubol N, Glanville J, et al. Resection of primary tumor site is associated with prolonged survival in metastatic nonfunctioning pancreatic neuroendocrine tumors. Surgery. 2016;159:311\u20138.","journal-title":"Surgery."},{"key":"10092_CR18","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1007\/s00464-010-1456-5","volume":"25","author":"GR Nigri","year":"2011","unstructured":"Nigri GR, Rosman AS, Petrucciani N, et al. Metaanalysis of trials comparing minimally invasive and open distal pancreatectomies. Surg Endosc. 2011;25:1642\u201351.","journal-title":"Surg Endosc."},{"key":"10092_CR19","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1097\/SLA.0b013e318251ee09","volume":"255","author":"R Venkat","year":"2012","unstructured":"Venkat R, Edil BH, Schulick RD, Lidor AO, Makary MA, Wolfgang CL. Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg. 2012;255:1048\u201359.","journal-title":"Ann Surg."},{"key":"10092_CR20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/jso.25481","volume":"120","author":"XF Zhang","year":"2019","unstructured":"Zhang XF, Lopez-Aguiar AG, Poultsides G, et al. Minimally invasive versus open distal pancreatectomy for pancreatic neuroendocrine tumors: an analysis from the U.S. neuroendocrine tumor study group. J Surg Oncol. 2019;120:231\u201340.","journal-title":"J Surg Oncol."},{"key":"10092_CR21","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1097\/00001648-200009000-00012","volume":"11","author":"MA Hernan","year":"2000","unstructured":"Hernan MA, Brumback B, Robins JM. Marginal structural models to estimate the causal effect of zidovudine on the survival of HIV-positive men. Epidemiology. 2000;11:561\u201370.","journal-title":"Epidemiology."},{"key":"10092_CR22","doi-asserted-by":"publisher","first-page":"S103","DOI":"10.1097\/MLR.0b013e31806518ac","volume":"45","author":"LH Curtis","year":"2007","unstructured":"Curtis LH, Hammill BG, Eisenstein EL, Kramer JM, Anstrom KJ. Using inverse probability-weighted estimators in comparative effectiveness analyses with observational databases. Med Care. 2007;45:S103\u20137.","journal-title":"Med Care."},{"key":"10092_CR23","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1200\/JCO.2017.75.9134","volume":"36","author":"RD Ennis","year":"2018","unstructured":"Ennis RD, Hu L, Ryemon SN, Lin J, Mazumdar M. Brachytherapy-based radiotherapy and radical prostatectomy are associated with similar survival in high-risk localized prostate cancer. J Clin Oncol. 2018;36:1192\u20138.","journal-title":"J Clin Oncol."},{"key":"10092_CR24","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1056\/NEJMoa1110717","volume":"366","author":"WS Weintraub","year":"2012","unstructured":"Weintraub WS, Grau-Sepulveda MV, Weiss JM, et al. Comparative effectiveness of revascularization strategies. N Engl J Med. 2012;366:1467\u201376.","journal-title":"N Engl J Med."},{"key":"10092_CR25","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1007\/s00464-019-06913-9","volume":"34","author":"KB Song","year":"2020","unstructured":"Song KB, Kim SC, Lee W, et al. Laparoscopic pancreaticoduodenectomy for periampullary tumors: lessons learned from 500 consecutive patients in a single center. Surg Endosc. 2020;34:1343\u201352.","journal-title":"Surg Endosc."},{"key":"10092_CR26","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-07724-z","author":"S Kim","year":"2020","unstructured":"Kim S, Yoon YS, Han HS, Cho JY, Choi Y, Lee B. Evaluation of a single surgeon\u2019s learning curve of laparoscopic pancreaticoduodenectomy: risk-adjusted cumulative summation analysis. Surg Endosc. 2020. https:\/\/doi.org\/10.1007\/s00464-020-07724-z.","journal-title":"Surg Endosc."},{"key":"10092_CR27","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/S2468-1253(19)30004-4","volume":"4","author":"J van Hilst","year":"2019","unstructured":"van Hilst J, de Rooij T, Bosscha K, et al. Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2\/3 trial. Lancet Gastroenterol Hepatol. 2019;4:199\u2013207.","journal-title":"Lancet Gastroenterol Hepatol."},{"key":"10092_CR28","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-020-08850-7","author":"M Tanaka","year":"2020","unstructured":"Tanaka M, Heckler M, Mihaljevic AL, et al. Systematic review and metaanalysis of lymph node metastases of resected pancreatic neuroendocrine tumors. Ann Surg Oncol. 2020. https:\/\/doi.org\/10.1245\/s10434-020-08850-7.","journal-title":"Ann Surg Oncol."},{"key":"10092_CR29","doi-asserted-by":"publisher","first-page":"7271","DOI":"10.1038\/s41598-018-24072-0","volume":"8","author":"Y Gao","year":"2018","unstructured":"Gao Y, Gao H, Wang G, et al. A meta-analysis of prognostic factor of pancreatic neuroendocrine neoplasms. Sci Rep. 2018;8:7271.","journal-title":"Sci Rep."},{"key":"10092_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2019.11.009","author":"DH Dong","year":"2019","unstructured":"Dong DH, Zhang XF, Lopez-Aguiar AG, et al. Tumor burden score predicts tumor recurrence of non-functional pancreatic neuroendocrine tumors after curative resection. HPB Oxf. 2019. https:\/\/doi.org\/10.1016\/j.hpb.2019.11.009.","journal-title":"HPB Oxf."},{"key":"10092_CR31","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1002\/jso.25716","volume":"120","author":"DH Dong","year":"2019","unstructured":"Dong DH, Zhang XF, Poultsides G, et al. Impact of tumor size and nodal status on recurrence of nonfunctional pancreatic neuroendocrine tumors \u22642 cm after curative resection: a multi-institutional study of 392 cases. J Surg Oncol. 2019;120:1071\u20139.","journal-title":"J Surg Oncol."},{"key":"10092_CR32","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/S0002-9610(88)80276-9","volume":"155","author":"CJ Davis","year":"1988","unstructured":"Davis CJ, Ilstrup DM, Pemberton JH. Influence of splenectomy on survival rate of patients with colorectal cancer. Am J Surg. 1988;155:173\u20139.","journal-title":"Am J Surg."},{"key":"10092_CR33","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1136\/gut.36.5.684","volume":"36","author":"JP Griffith","year":"1995","unstructured":"Griffith JP, Sue-Ling HM, Martin I, et al. Preservation of the spleen improves survival after radical surgery for gastric cancer. Gut. 1995;36:684\u201390.","journal-title":"Gut."},{"key":"10092_CR34","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/S1072-7515(99)00041-1","volume":"188","author":"RE Schwarz","year":"1999","unstructured":"Schwarz RE, Harrison LE, Conlon KC, Klimstra DS, Brennan MF. The impact of splenectomy on outcomes after resection of pancreatic adenocarcinoma. J Am Coll Surg. 1999;188:516\u201321.","journal-title":"J Am Coll Surg."},{"key":"10092_CR35","doi-asserted-by":"publisher","first-page":"2398","DOI":"10.1007\/BF02063244","volume":"40","author":"Y Shiratori","year":"1995","unstructured":"Shiratori Y, Kawase T, Nakata R, et al. Effect of splenectomy on hepatic metastasis of colon carcinoma and natural killer activity in the liver. Dig Dis Sci. 1995;40:2398\u2013406.","journal-title":"Dig Dis Sci."},{"key":"10092_CR36","first-page":"385","volume":"29","author":"J Higashijima","year":"2009","unstructured":"Higashijima J, Shimada M, Chikakiyo M, et al. Effect of splenectomy on antitumor immune system in mice. Anticancer Res. 2009;29:385\u201393.","journal-title":"Anticancer Res."},{"key":"10092_CR37","doi-asserted-by":"publisher","first-page":"88827","DOI":"10.18632\/oncotarget.21331","volume":"8","author":"HK Hwang","year":"2017","unstructured":"Hwang HK, Murakami T, Kiyuna T, et al. Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model. Oncotarget. 2017;8:88827\u201334.","journal-title":"Oncotarget."}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-021-10092-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-021-10092-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-021-10092-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T13:33:05Z","timestamp":1699018385000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-021-10092-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,9]]},"references-count":37,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10092"],"URL":"https:\/\/doi.org\/10.1245\/s10434-021-10092-0","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,9]]},"assertion":[{"value":"18 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"There are no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}