{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:15:14Z","timestamp":1772532914704,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1245\/s10434-024-14900-1","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T16:03:50Z","timestamp":1706803430000},"page":"3742-3749","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Continuous Wound Irrigation and Intraoperative Methadone Decreases Opioid Use and Shortens Length of Stay After CRS\/HIPEC"],"prefix":"10.1245","volume":"31","author":[{"given":"Markus A.","family":"Boesl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noah","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh","family":"Bleicher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Call","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald H.","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura A.","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"issue":"1","key":"14900_CR1","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12957-020-01842-7","volume":"18","author":"X Wang","year":"2020","unstructured":"Wang X, Li T. Postoperative pain pathophysiology and treatment strategies after CRS + HIPEC for peritoneal cancer. World J Surg Oncol. 2020;18(1):62. https:\/\/doi.org\/10.1186\/s12957-020-01842-7.","journal-title":"World J Surg Oncol"},{"issue":"1","key":"14900_CR2","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1245\/s10434-019-07900-z","volume":"27","author":"C Webb","year":"2020","unstructured":"Webb C, Day R, Velazco CS, et al. Implementation of an enhanced recovery after surgery (eras) program is associated with improved outcomes in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol. 2020;27(1):303\u201312. https:\/\/doi.org\/10.1245\/s10434-019-07900-z.","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"14900_CR3","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1213\/ANE.0b013e3182860fff","volume":"116","author":"CAJ Webb","year":"2013","unstructured":"Webb CAJ, Weyker PD, Moitra VK, Raker RK. An overview of cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion for the anesthesiologist. Anesth Analg. 2013;116(4):924\u201331. https:\/\/doi.org\/10.1213\/ANE.0b013e3182860fff.","journal-title":"Anesth Analg"},{"issue":"3","key":"14900_CR4","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1097\/ACO.0b013e32835347b2","volume":"25","author":"C Raspe","year":"2012","unstructured":"Raspe C, Piso P, Wiesenack C, Bucher M. Anesthetic management in patients undergoing hyperthermic chemotherapy. Curr Opin Anaesthesiol. 2012;25(3):348\u201355. https:\/\/doi.org\/10.1097\/ACO.0b013e32835347b2.","journal-title":"Curr Opin Anaesthesiol"},{"issue":"Pt A","key":"14900_CR5","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.ijsu.2015.02.025","volume":"16","author":"F Piccioni","year":"2015","unstructured":"Piccioni F, Casiraghi C, Fumagalli L, et al. Epidural analgesia for cytoreductive surgery with peritonectomy and heated intraperitoneal chemotherapy. Int J Surg Lond Engl. 2015;16(Pt A):99\u2013106. https:\/\/doi.org\/10.1016\/j.ijsu.2015.02.025.","journal-title":"Int J Surg Lond Engl"},{"key":"14900_CR6","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jss.2019.10.042","volume":"247","author":"PW Lu","year":"2020","unstructured":"Lu PW, Fields AC, Shabat G, et al. Cytoreductive surgery and HIPEC in an enhanced recovery after surgery program: a feasibility study. J Surg Res. 2020;247:59\u201365. https:\/\/doi.org\/10.1016\/j.jss.2019.10.042.","journal-title":"J Surg Res."},{"issue":"3","key":"14900_CR7","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1515\/pp-2021-0117","volume":"6","author":"G Bhandoria","year":"2021","unstructured":"Bhandoria G, Solanki SL, Bhavsar M, et al. Enhanced recovery after surgery (ERAS) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC): a cross-sectional survey. Pleura Peritoneum. 2021;6(3):99\u2013111. https:\/\/doi.org\/10.1515\/pp-2021-0117.","journal-title":"Pleura Peritoneum"},{"issue":"6","key":"14900_CR8","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1016\/j.amjsurg.2020.08.041","volume":"220","author":"RC Martin","year":"2020","unstructured":"Martin RC, Marshall BM, Philips P, Egger M, McMasters KM, Scoggins CR. Enhanced recovery after surgery is safe for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Am J Surg. 2020;220(6):1428\u201332. https:\/\/doi.org\/10.1016\/j.amjsurg.2020.08.041.","journal-title":"Am J Surg"},{"issue":"12","key":"14900_CR9","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.1016\/j.ejso.2020.08.006","volume":"46","author":"M H\u00fcbner","year":"2020","unstructured":"H\u00fcbner M, Kusamura S, Villeneuve L, et al. Guidelines for Perioperative Care in Cytoreductive Surgery (CRS) with or without hyperthermic IntraPEritoneal chemotherapy (HIPEC): enhanced Recovery After Surgery (ERAS\u00ae) Society Recommendations\u2014part II: postoperative management and special considerations. Eur J Surg Oncol. 2020;46(12):2311\u201323. https:\/\/doi.org\/10.1016\/j.ejso.2020.08.006.","journal-title":"Eur J Surg Oncol"},{"issue":"9","key":"14900_CR10","doi-asserted-by":"publisher","first-page":"5265","DOI":"10.1245\/s10434-020-09476-5","volume":"28","author":"B White","year":"2021","unstructured":"White B, Dahdaleh F, Naffouje SA, et al. Impact of enhanced recovery after surgery on postoperative outcomes for patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol. 2021;28(9):5265\u201372. https:\/\/doi.org\/10.1245\/s10434-020-09476-5.","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"14900_CR11","doi-asserted-by":"publisher","first-page":"75","DOI":"10.17085\/apm.21094","volume":"17","author":"J Song","year":"2022","unstructured":"Song J, Choi N, Kang M, Ji SM, Kim DW, Kwon MA. Analgesic effects of ultrasound-guided fourquadrant transversus abdominis plane in patients with cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a prospective, randomized, controlled study. Anesth Pain Med. 2022;17(1):75\u201386. https:\/\/doi.org\/10.17085\/apm.21094.","journal-title":"Anesth Pain Med"},{"issue":"2","key":"14900_CR12","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1308\/rcsann.2019.0159","volume":"102","author":"FH Koh","year":"2020","unstructured":"Koh FH, Ng JY, Seow CS, Keh CH. ON-Q pain relief system insertion technique: intraoperative insertion of a pre-peritoneal catheter for continuous local anaesthetic infusion. Ann R Coll Surg Engl. 2020;102(2):160\u20131. https:\/\/doi.org\/10.1308\/rcsann.2019.0159.","journal-title":"Ann R Coll Surg Engl"},{"issue":"2","key":"14900_CR13","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.jamcollsurg.2005.10.022","volume":"202","author":"MK Baig","year":"2006","unstructured":"Baig MK, Zmora O, Derdemezi J, Weiss EG, Nogueras JJ, Wexner SD. Use of the ON-Q pain management system is associated with decreased postoperative analgesic requirement: double blind randomized placebo pilot study. J Am Coll Surg. 2006;202(2):297\u2013305. https:\/\/doi.org\/10.1016\/j.jamcollsurg.2005.10.022.","journal-title":"J Am Coll Surg"},{"issue":"3","key":"14900_CR14","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1097\/ALN.0000000000002755","volume":"131","author":"GS Murphy","year":"2019","unstructured":"Murphy GS, Szokol JW. Intraoperative methadone in surgical patients: a review of clinical investigations. Anesthesiology. 2019;131(3):678\u201392. https:\/\/doi.org\/10.1097\/ALN.0000000000002755.","journal-title":"Anesthesiology"},{"issue":"4","key":"14900_CR15","doi-asserted-by":"publisher","first-page":"377","DOI":"10.5055\/jom.2022.0730","volume":"18","author":"AK Tabbara","year":"2022","unstructured":"Tabbara AK, Krishnan S, Vaynberg E, Spence NZ, Lambert DH. Intraoperative methadone: proceed with care. J Opioid Manag. 2022;18(4):377\u201383. https:\/\/doi.org\/10.5055\/jom.2022.0730.","journal-title":"J Opioid Manag"},{"issue":"9","key":"14900_CR16","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1002\/lt.23691","volume":"19","author":"SH Lee","year":"2013","unstructured":"Lee SH, Gwak MS, Choi SJ, et al. Prospective, randomized study of ropivacaine wound infusion versus intrathecal morphine with intravenous fentanyl for analgesia in living donors for liver transplantation. Liver Transpl. 2013;19(9):1036\u201345. https:\/\/doi.org\/10.1002\/lt.23691.","journal-title":"Liver Transpl"},{"issue":"1","key":"14900_CR17","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4236\/ojanes.2013.31002","volume":"3","author":"JM Soliz","year":"2013","unstructured":"Soliz JM, Gebhardt R, Feng L, Dong W, Reich M, Curley S. Comparing epidural analgesia and ON-Q infiltrating catheters for pain management after hepatic resection. Open J Anesthesiol. 2013;3(1):3\u20137. https:\/\/doi.org\/10.4236\/ojanes.2013.31002.","journal-title":"Open J Anesthesiol"},{"issue":"5","key":"14900_CR18","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1007\/s00404-017-4342-8","volume":"295","author":"B Lee","year":"2017","unstructured":"Lee B, Kim K, Ahn S, et al. Continuous wound infiltration system for postoperative pain management in gynecologic oncology patients. Arch Gynecol Obstet. 2017;295(5):1219\u201326. https:\/\/doi.org\/10.1007\/s00404-017-4342-8.","journal-title":"Arch Gynecol Obstet."},{"key":"14900_CR19","unstructured":"[The effects of the administration of subfacial levobupivacaine infusion with the ON-Q pain pump system on postoperative analgesia and tramadol consumption in cesarean operations] - PubMed. Accessed July 19, 2022. https:\/\/pubmed.ncbi.nlm.nih.gov\/20582749\/"},{"issue":"6","key":"14900_CR20","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1093\/bja\/aen309","volume":"101","author":"E Forastiere","year":"2008","unstructured":"Forastiere E, Sofra M, Giannarelli D, Fabrizi L, Simone G. Effectiveness of continuous wound infusion of 0.5% ropivacaine by On-Q pain relief system for postoperative pain management after open nephrectomy. Br J Anaesth. 2008;101(6):841\u20137. https:\/\/doi.org\/10.1093\/bja\/aen309.","journal-title":"Br J Anaesth"},{"issue":"2","key":"14900_CR21","doi-asserted-by":"publisher","first-page":"93","DOI":"10.5468\/OGS.2013.56.2.93","volume":"56","author":"D Chung","year":"2013","unstructured":"Chung D, Lee YJ, Jo MH, et al. The ON-Q pain management system in elective gynecology oncologic surgery: management of postoperative surgical site pain compared to intravenous patient-controlled analgesia. Obstet Gynecol Sci. 2013;56(2):93\u2013101. https:\/\/doi.org\/10.5468\/OGS.2013.56.2.93.","journal-title":"Obstet Gynecol Sci"},{"issue":"3","key":"14900_CR22","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1053\/j.jvca.2013.02.017","volume":"27","author":"R Gebhardt","year":"2013","unstructured":"Gebhardt R, Mehran RJ, Soliz J, Cata JP, Smallwood AK, Feeley TW. Epidural versus ON-Q local anesthetic-infiltrating catheter for post-thoracotomy pain control. J Cardiothorac Vasc Anesth. 2013;27(3):423\u20136. https:\/\/doi.org\/10.1053\/j.jvca.2013.02.017.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"4","key":"14900_CR23","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1053\/j.jvca.2013.12.028","volume":"28","author":"M Ried","year":"2014","unstructured":"Ried M, Schilling C, Potzger T, et al. Prospective, comparative study of the On-Q\u00ae PainBuster\u00ae postoperative pain relief system and thoracic epidural analgesia after thoracic surgery. J Cardiothorac Vasc Anesth. 2014;28(4):973\u20138.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"2","key":"14900_CR24","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.jtcvs.2005.02.011","volume":"130","author":"GH Wheatley","year":"2005","unstructured":"Wheatley GH, Rosenbaum DH, Paul MC, et al. Improved pain management outcomes with continuous infusion of a local anesthetic after thoracotomy. J Thorac Cardiovasc Surg. 2005;130(2):464\u20138. https:\/\/doi.org\/10.1016\/j.jtcvs.2005.02.011.","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"4","key":"14900_CR25","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.phrs.2009.04.002","volume":"60","author":"ML Sotgiu","year":"2009","unstructured":"Sotgiu ML, Valente M, Storchi R, Caramenti G, Biella GEM. Cooperative N-methyl-D-aspartate (NMDA) receptor antagonism and mu-opioid receptor agonism mediate the methadone inhibition of the spinal neuron pain-related hyperactivity in a rat model of neuropathic pain. Pharmacol Res. 2009;60(4):284\u201390. https:\/\/doi.org\/10.1016\/j.phrs.2009.04.002.","journal-title":"Pharmacol Res."},{"issue":"10","key":"14900_CR26","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1097\/EJA.0000000000001217","volume":"37","author":"E Tognoli","year":"2020","unstructured":"Tognoli E, Proto PL, Motta G, Galeone C, Mariani L, Valenza F. Methadone for postoperative analgesia: contribution of N-methyl-D-aspartate receptor antagonism: a randomised controlled trial. Eur J Anaesthesiol. 2020;37(10):934\u201343. https:\/\/doi.org\/10.1097\/EJA.0000000000001217.","journal-title":"Eur J Anaesthesiol"},{"issue":"6","key":"14900_CR27","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1213\/ANE.0000000000004404","volume":"129","author":"FC Machado","year":"2019","unstructured":"Machado FC, Vieira JE, de Orange FA, Ashmawi HA. Intraoperative methadone reduces pain and opioid consumption in acute postoperative pain: a systematic review and meta-analysis. Anesth Analg. 2019;129(6):1723\u201332. https:\/\/doi.org\/10.1213\/ANE.0000000000004404.","journal-title":"Anesth Analg"},{"issue":"6","key":"14900_CR28","doi-asserted-by":"publisher","first-page":"443","DOI":"10.5055\/jom.2020.0602","volume":"16","author":"SE Bova","year":"2020","unstructured":"Bova SE, Kruer RM, Nesbit SA, Grant MC, Jarrell AS. Perioperative methadone prescribing and association with respiratory depression. J Opioid Manag. 2020;16(6):443\u20139. https:\/\/doi.org\/10.5055\/jom.2020.0602.","journal-title":"J Opioid Manag"},{"key":"14900_CR29","doi-asserted-by":"publisher","first-page":"100138","DOI":"10.1016\/j.dadr.2023.100138","volume":"6","author":"A Carl","year":"2023","unstructured":"Carl A, Pasman E, Broman MJ, Lister JJ, Agius E, Resko SM. Experiences of healthcare and substance use treatment provider-based stigma among patients receiving methadone. Drug Alcohol Depend Rep. 2023;6:100138. https:\/\/doi.org\/10.1016\/j.dadr.2023.100138.","journal-title":"Drug Alcohol Depend Rep."}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-14900-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-024-14900-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-14900-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T13:04:09Z","timestamp":1715087049000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-024-14900-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["14900"],"URL":"https:\/\/doi.org\/10.1245\/s10434-024-14900-1","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]},"assertion":[{"value":"21 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 December 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no financial relationships to disclose. There are no funding sources to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}}]}}