{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:46:14Z","timestamp":1791229574859,"version":"4.1.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"13","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1245\/s10434-024-16058-2","type":"journal-article","created":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T18:01:58Z","timestamp":1723917718000},"page":"9117-9124","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Feasibility of Using Needle Rinse Fluid for Cobas Human Papillomavirus (HPV) Assay in Diagnosing HPV+ Oropharyngeal Cancer with Neck Lymph Node Aspiration"],"prefix":"10.1245","volume":"31","author":[{"given":"Chun-Wei","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Chang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yang","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Jen","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Yuan","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Shu","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tseng-Cheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"issue":"5","key":"16058_CR1","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/s41571-022-00603-7","volume":"19","author":"M Lechner","year":"2022","unstructured":"Lechner M, Liu J, Masterson L, Fenton TR. HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management. Nat Rev Clin Oncol. 2022;19(5):306\u201327.","journal-title":"Nat Rev Clin Oncol"},{"issue":"5","key":"16058_CR2","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3322\/caac.21293","volume":"65","author":"AC Chi","year":"2015","unstructured":"Chi AC, Day TA, Neville BW. Oral cavity and oropharyngeal squamous cell carcinoma\u2013an update. CA Cancer J Clin. 2015;65(5):401\u201321.","journal-title":"CA Cancer J Clin"},{"issue":"3","key":"16058_CR3","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1001\/jamaoto.2015.3228","volume":"142","author":"K Motz","year":"2016","unstructured":"Motz K, Qualliotine JR, Rettig E, et al. Changes in unknown primary squamous cell carcinoma of the head and neck at initial presentation in the era of human papillomavirus. JAMA Otolaryngol Head Neck Surg. 2016;142(3):223\u20138.","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"12","key":"16058_CR4","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1002\/cncy.21742","volume":"124","author":"PA VanderLaan","year":"2016","unstructured":"VanderLaan PA. Fine-needle aspiration and core needle biopsy: An update on 2 common minimally invasive tissue sampling modalities. Cancer Cytopathol. 2016;124(12):862\u201370.","journal-title":"Cancer Cytopathol"},{"key":"16058_CR5","doi-asserted-by":"crossref","unstructured":"Lydiatt WM, Patel SG, O'Sullivan B et al. Head and Neck cancers-major changes in the American Joint Committee on cancer eighth edition cancer staging manual. CA Cancer J Clin 2017; 67 (2): 122-137.","DOI":"10.3322\/caac.21389"},{"issue":"7","key":"16058_CR6","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1002\/cncy.22563","volume":"130","author":"M Guo","year":"2022","unstructured":"Guo M, Khanna A, Tinnirello AA, et al. Detection accuracy of the Cobas HPV assay for high-risk HPV in head and neck FNA biopsy specimens. Cancer Cytopathol. 2022;130(7):523\u201330.","journal-title":"Cancer Cytopathol"},{"issue":"3","key":"16058_CR7","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/cncy.21372","volume":"122","author":"DA Kerr","year":"2014","unstructured":"Kerr DA, Pitman MB, Sweeney B, et al. Performance of the Roche cobas 4800 high-risk human papillomavirus test in cytologic preparations of squamous cell carcinoma of the head and neck. Cancer Cytopathol. 2014;122(3):167\u201374.","journal-title":"Cancer Cytopathol"},{"issue":"2","key":"16058_CR8","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/cncy.21240","volume":"121","author":"M Guo","year":"2013","unstructured":"Guo M, Gong Y, Wang J, et al. The role of human papillomavirus type 16\/18 genotyping in predicting high-grade cervical\/vaginal intraepithelial neoplasm in women with mildly abnormal Papanicolaou results. Cancer Cytopathol. 2013;121(2):79\u201385.","journal-title":"Cancer Cytopathol"},{"issue":"4","key":"16058_CR9","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.jcv.2013.04.010","volume":"57","author":"LA Lee","year":"2013","unstructured":"Lee LA, Huang CG, Tsao KC, et al. Increasing rates of low-risk human papillomavirus infections in patients with oral cavity squamous cell carcinoma: association with clinical outcomes. J Clin Virol. 2013;57(4):331\u20137.","journal-title":"J Clin Virol"},{"issue":"4","key":"16058_CR10","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1136\/ijgc-00009577-200407000-00012","volume":"14","author":"HJ Huang","year":"2004","unstructured":"Huang HJ, Huang SL, Lin CY, et al. Human papillomavirus genotyping by a polymerase chain reaction-based genechip method in cervical carcinoma treated with neoadjuvant chemotherapy plus radical surgery. Int J Gynecol Cancer. 2004;14(4):639\u201349.","journal-title":"Int J Gynecol Cancer"},{"issue":"1","key":"16058_CR11","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1186\/s12885-022-09407-5","volume":"22","author":"CP Wang","year":"2022","unstructured":"Wang CP, Chen TC, Hsu WL, et al. Rising incidence of HPV positive oropharyngeal cancer in Taiwan between 1999 and 2014 where betel nut chewing is common. BMC Cancer. 2022;22(1):296.","journal-title":"BMC Cancer"},{"issue":"1","key":"16058_CR12","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/s41572-020-00224-3","volume":"6","author":"DE Johnson","year":"2020","unstructured":"Johnson DE, Burtness B, Leemans CR, et al. Head and neck squamous cell carcinoma. Nat Rev Dis Primers. 2020;6(1):92.","journal-title":"Nat Rev Dis Primers"},{"issue":"5","key":"16058_CR13","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1001\/jamaoto.2014.141","volume":"140","author":"WR McIlwain","year":"2014","unstructured":"McIlwain WR, Sood AJ, Nguyen SA, Day TA. Initial symptoms in patients with HPV-positive and HPV-negative oropharyngeal cancer. JAMA Otolaryngol Head Neck Surg. 2014;140(5):441\u20137.","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"16058_CR14","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.radonc.2021.01.028","volume":"157","author":"L Bauwens","year":"2021","unstructured":"Bauwens L, Baltres A, Fiani DJ, et al. Prevalence and distribution of cervical lymph node metastases in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma. Radiother Oncol. 2021;157:122\u20139.","journal-title":"Radiother Oncol"},{"key":"16058_CR15","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1146\/annurev-pathmechdis-031521-041424","volume":"18","author":"RL Ferris","year":"2023","unstructured":"Ferris RL, Westra W. Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma. Annu Rev Pathol. 2023;18:515\u201335.","journal-title":"Annu Rev Pathol"},{"issue":"6","key":"16058_CR16","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1177\/000348941112000611","volume":"120","author":"J Sira","year":"2011","unstructured":"Sira J, Makura ZG. Differential diagnosis of cystic neck lesions. Ann Otol Rhinol Laryngol. 2011;120(6):409\u201313.","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"4","key":"16058_CR17","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1017\/S0022215106000284","volume":"120","author":"CP Wang","year":"2006","unstructured":"Wang CP, Ko JY, Lou PJ. Deep neck infection as the main initial presentation of primary head and neck cancer. J Laryngol Otol. 2006;120(4):305\u20139.","journal-title":"J Laryngol Otol"},{"issue":"2","key":"16058_CR18","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1002\/lary.27946","volume":"130","author":"RJ Davis","year":"2020","unstructured":"Davis RJ, Rettig E, Aygun N, et al. From presumed benign neck masses to delayed recognition of human papillomavirus-positive oropharyngeal cancer. Laryngoscope. 2020;130(2):392\u20137.","journal-title":"Laryngoscope"},{"issue":"11","key":"16058_CR19","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1002\/hed.20891","volume":"30","author":"M Kraft","year":"2008","unstructured":"Kraft M, Laeng H, Schmuziger N, et al. Comparison of ultrasound-guided core-needle biopsy and fine-needle aspiration in the assessment of head and neck lesions. Head Neck. 2008;30(11):1457\u201363.","journal-title":"Head Neck"},{"issue":"7","key":"16058_CR20","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1002\/cncy.22258","volume":"128","author":"MF Wright","year":"2020","unstructured":"Wright MF, Weiss VL, Lewis JS Jr, et al. Determination of high-risk HPV status of head and neck squamous cell carcinoma using the Roche cobas HPV test on cytologic specimens and acellular supernatant fluid. Cancer Cytopathol. 2020;128(7):482\u201390.","journal-title":"Cancer Cytopathol"},{"issue":"11","key":"16058_CR21","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1016\/j.annonc.2020.07.011","volume":"31","author":"JP Machiels","year":"2020","unstructured":"Machiels JP, Rene Leemans C, Golusinski W, et al. Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020;31(11):1462\u201375.","journal-title":"Ann Oncol"},{"issue":"11","key":"16058_CR22","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1002\/hed.23190","volume":"35","author":"J Vent","year":"2013","unstructured":"Vent J, Haidle B, Wedemeyer I, et al. p16 expression in carcinoma of unknown primary: diagnostic indicator and prognostic marker. Head Neck. 2013;35(11):1521\u20136.","journal-title":"Head Neck"},{"issue":"5","key":"16058_CR23","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.jasc.2022.05.003","volume":"11","author":"V Manucha","year":"2022","unstructured":"Manucha V, Adeniran AJ, Asiry S, et al. High-risk human papillomavirus testing in cytology aspiration samples from the head and neck part 1: a review of the literature on available testing options. J Am Soc Cytopathol. 2022;11(5):295\u2013305.","journal-title":"J Am Soc Cytopathol"},{"issue":"9","key":"16058_CR24","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1002\/hed.20849","volume":"30","author":"S Tandon","year":"2008","unstructured":"Tandon S, Shahab R, Benton JI, et al. Fine-needle aspiration cytology in a regional head and neck cancer center: comparison with a systematic review and meta-analysis. Head Neck. 2008;30(9):1246\u201352.","journal-title":"Head Neck"},{"issue":"31","key":"16058_CR25","doi-asserted-by":"publisher","first-page":"3152","DOI":"10.1200\/JCO.18.00684","volume":"36","author":"C Fakhry","year":"2018","unstructured":"Fakhry C, Lacchetti C, Rooper LM, et al. Human papillomavirus testing in head and neck carcinomas: ASCO clinical practice guideline endorsement of the college of american pathologists guideline. J Clin Oncol. 2018;36(31):3152\u201361.","journal-title":"J Clin Oncol"},{"issue":"11","key":"16058_CR26","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1097\/PAS.0b013e3182299cde","volume":"35","author":"JA Bishop","year":"2011","unstructured":"Bishop JA, Westra WH. Human papillomavirus-related small cell carcinoma of the oropharynx. Am J Surg Pathol. 2011;35(11):1679\u201384.","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"16058_CR27","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s12105-011-0285-8","volume":"5","author":"B Wadsworth","year":"2011","unstructured":"Wadsworth B, Bumpous JM, Martin AW, et al. Expression of p16 in sinonasal undifferentiated carcinoma (SNUC) without associated human papillomavirus (HPV). Head Neck Pathol. 2011;5(4):349\u201354.","journal-title":"Head Neck Pathol"},{"issue":"4","key":"16058_CR28","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.humpath.2009.09.006","volume":"41","author":"D Cao","year":"2010","unstructured":"Cao D, Begum S, Ali SZ, Westra WH. Expression of p16 in benign and malignant cystic squamous lesions of the neck. Hum Pathol. 2010;41(4):535\u20139.","journal-title":"Hum Pathol"},{"issue":"Suppl 1","key":"16058_CR29","doi-asserted-by":"publisher","first-page":"S83","DOI":"10.1007\/s12105-012-0370-7","volume":"6","author":"M Robinson","year":"2012","unstructured":"Robinson M, Schache A, Sloan P, Thavaraj S. HPV specific testing: a requirement for oropharyngeal squamous cell carcinoma patients. Head Neck Pathol. 2012;6(Suppl 1):S83-90.","journal-title":"Head Neck Pathol"},{"issue":"1","key":"16058_CR30","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.jmoldx.2011.09.005","volume":"14","author":"ML Lindemann","year":"2012","unstructured":"Lindemann ML, Dominguez MJ, de Antonio JC, et al. Analytical comparison of the cobas HPV test with hybrid capture 2 for the detection of high-risk HPV genotypes. J Mol Diagn. 2012;14(1):65\u201370.","journal-title":"J Mol Diagn"},{"issue":"10","key":"16058_CR31","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1002\/cncy.21480","volume":"122","author":"R Nayar","year":"2014","unstructured":"Nayar R, Goulart RA, Tiscornia-Wasserman PG, Davey DD. Primary human papillomavirus screening for cervical cancer in the United States\u2014US food and drug administration approval, clinical trials, and where we are today. Cancer Cytopathol. 2014;122(10):720\u20139.","journal-title":"Cancer Cytopathol"},{"issue":"5","key":"16058_CR32","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.jasc.2022.06.005","volume":"11","author":"A van Zante","year":"2022","unstructured":"van Zante A, Flanagan MB, Floyd AD, et al. High-risk human papillomavirus testing in cytology aspiration samples from the head and neck part 2: a survey of the American society of cytopathology community. J Am Soc Cytopathol. 2022;11(5):306\u201312.","journal-title":"J Am Soc Cytopathol"},{"issue":"9","key":"16058_CR33","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1001\/archotol.126.9.1091","volume":"126","author":"M Knappe","year":"2000","unstructured":"Knappe M, Louw M, Gregor RT. Ultrasonography-guided fine-needle aspiration for the assessment of cervical metastases. Arch Otolaryngol Head Neck Surg. 2000;126(9):1091\u20136.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"3","key":"16058_CR34","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.bjoms.2016.01.004","volume":"54","author":"KS Shah","year":"2016","unstructured":"Shah KS, Ethunandan M. Tumour seeding after fine-needle aspiration and core biopsy of the head and neck\u2013a systematic review. Br J Oral Maxillofac Surg. 2016;54(3):260\u20135.","journal-title":"Br J Oral Maxillofac Surg"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-16058-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-024-16058-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-16058-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T13:03:59Z","timestamp":1731071039000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-024-16058-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,17]]},"references-count":34,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["16058"],"URL":"https:\/\/doi.org\/10.1245\/s10434-024-16058-2","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,17]]},"assertion":[{"value":"11 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Chun-Wei Chang, Po-Chang Lin, Chun-Yang Hung, Cheng-Ping Wang, Pei-Jen Lou, Shu-Yuan Ho, Ming-Shu Hsieh, and Tseng-Cheng Chen declare no conflicts of interest that may be relevant to the contents of this article.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}