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Paraplegic RC patients were younger (\u226470\u00a0years of age; 75 vs. 53%), more frequently female (28 vs. 19%), and more frequently harbored Charlson Comorbidity Index \u22653 (56 vs. 18%). Of paraplegic vs. non-paraplegic RC patients, 141 versus 15,112 (76 vs. 60%) experienced overall complications, 38 versus 2794 (21 vs. 11%) pulmonary complications, 36 versus 3525 (19 vs. 14%) genitourinary complications, 33 versus 3087 (18 vs. 12%) intraoperative complications, 21 versus 1035 (11 vs. 4%) infections, and 17 versus 1343 (9 vs. 5%) wound complications, while 62 versus 6267 (34 vs. 25%) received blood transfusions, 47 versus 3044 (25 vs. 12%) received critical care therapy (CCT), and intrahospital mortality was recorded in 13 versus 456 (7.0 vs. 1.8%) patients. In multivariable logistic regression models, paraplegic status independently predicted higher overall CCT use (odds ratio [OR] 2.1, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) as well as fourfold higher in-hospital mortality (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), higher infection rate (OR 2.5, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), higher blood transfusion rate (OR 1.45, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.009), and higher intraoperative (OR 1.56, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.02), wound (OR 1.89, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01), and pulmonary (OR 1.72, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.004) complication rates.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Paraplegic patients contemplating RC should be counseled about fourfold higher risk of in-hospital mortality and higher rates of other untoward effects.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1245\/s10434-024-16332-3","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T14:02:35Z","timestamp":1728396155000},"page":"583-588","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Perioperative Complications and In-Hospital Mortality in Paraplegic Radical Cystectomy Patients"],"prefix":"10.1245","volume":"32","author":[{"given":"Francesco","family":"Di Bello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolin","family":"Siech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"de Angelis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natali","family":"Rodriguez Pe\u00f1aranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan A.","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Coll\u00e0 Ruvolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Califano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimiliano","family":"Creta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Saad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix K. 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