{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T10:00:46Z","timestamp":1763978446771,"version":"3.38.0"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>Pancreatoduodenectomy (PD) is a complex surgery with high morbidity and mortality, often associated with complications like post-pancreatectomy hemorrhage (PPH) and postoperative pancreatic fistulas (POPF). The corticosteroids administered intraoperatively has been shown to improve postoperative outcomes in patients undergoing surgery. However, their impact on complications following PD remains controversial.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>A comprehensive review of literature found no significant impact of perioperative corticosteroids on postoperative complications in PD, including postoperative major complications (PMCs), POPF, infectious complications, delayed gastric emptying (DGE), post-pancreatectomy hemorrhage (PPH), bile leakage, reoperation, or 30-days mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Other medications, such as octreotide, antibiotics, and probiotics, have shown potential in reducing complications, but further research is needed, especially for corticosteroids in PD. In the near future, more randomized controlled trials should be conducted, along with well-designed clinical studies, to provide high-level evidence for the potential benefits of corticosteroids in PD for targeted populations.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1245\/s10434-024-16831-3","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T13:33:28Z","timestamp":1737725608000},"page":"2856-2858","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["ASO Author Reflections: The Effects of Perioperative Corticosteroids on Postoperative Complications After Pancreatoduodenectomy: A Debated Topic of Systematic Review and Meta-analysis"],"prefix":"10.1245","volume":"32","author":[{"given":"Haonan","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kongyuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,24]]},"reference":[{"issue":"2","key":"16831_CR1","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1097\/aln.0000000000000489","volume":"122","author":"TR Call","year":"2015","unstructured":"Call TR, Pace NL, Thorup DB, et al. Factors associated with improved survival after resection of pancreatic adenocarcinoma: a multivariable model. Anesthesiology. 2015;122(2):317\u201324. https:\/\/doi.org\/10.1097\/aln.0000000000000489.","journal-title":"Anesthesiology."},{"issue":"11","key":"16831_CR2","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/j.hpb.2018.05.004","volume":"20","author":"E Kim","year":"2018","unstructured":"Kim E, Kang JS, Han Y, et al. Influence of preoperative nutritional status on clinical outcomes after pancreatoduodenectomy. HPB. 2018;20(11):1051\u201361. https:\/\/doi.org\/10.1016\/j.hpb.2018.05.004.","journal-title":"HPB."},{"key":"16831_CR3","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-024-16704-9","author":"HN Liu","year":"2024","unstructured":"Liu HN, Wei KY, Cao RQ, et al. The effects of perioperative corticosteroids on postoperative complications after Pancreatoduodenectomy: a debated topic of systematic review and meta-analysis. Ann Surg Oncol. 2024. https:\/\/doi.org\/10.1245\/s10434-024-16704-9.","journal-title":"Ann Surg Oncol."},{"issue":"10","key":"16831_CR4","doi-asserted-by":"publisher","first-page":"Cd012859","DOI":"10.1002\/14651858.CD012859.pub2","volume":"10","author":"S Weibel","year":"2020","unstructured":"Weibel S, R\u00fccker G, Eberhart LH, et al. Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis. Cochrane Database Systemat Rev. 2020;10(10):Cd012859. https:\/\/doi.org\/10.1002\/14651858.CD012859.pub2.","journal-title":"Cochrane Database Systemat Rev"},{"issue":"3","key":"16831_CR5","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1097\/sla.0000000000005955","volume":"278","author":"RJ Ellis","year":"2023","unstructured":"Ellis RJ, Brajcich BC, Bertens KA, et al. Association between biliary pathogens, surgical site infection, and pancreatic fistula: results of a randomized trial of perioperative antibiotic prophylaxis in patients undergoing pancreatoduodenectomy. Ann Surg. 2023;278(3):310\u20139. https:\/\/doi.org\/10.1097\/sla.0000000000005955.","journal-title":"Ann Surg."}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-16831-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-024-16831-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-024-16831-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T17:28:48Z","timestamp":1741195728000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-024-16831-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,24]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["16831"],"URL":"https:\/\/doi.org\/10.1245\/s10434-024-16831-3","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"type":"print","value":"1068-9265"},{"type":"electronic","value":"1534-4681"}],"subject":[],"published":{"date-parts":[[2025,1,24]]},"assertion":[{"value":"17 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All authors have no conflict of interests to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}}]}}