{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T20:50:10Z","timestamp":1777323010763,"version":"3.51.4"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ann Surg Oncol"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1245\/s10434-025-17075-5","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T18:32:19Z","timestamp":1740508339000},"page":"4352-4362","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Improved Outcomes Following Resection of Perihilar Cholangiocarcinoma: A 27-Year Experience"],"prefix":"10.1245","volume":"32","author":[{"given":"Anish J.","family":"Jain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateo","family":"Lendoire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antony","family":"Haddad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Wei D.","family":"Tzeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artem","family":"Boyev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harufumi","family":"Maki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Shin","family":"Chun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsa M.","family":"Arvide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunyoung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shubham","family":"Pant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milind","family":"Javle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hop S.","family":"Tran Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Nicolas","family":"Vauthey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy E.","family":"Newhook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"issue":"2","key":"17075_CR1","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1097\/00000658-200008000-00003","volume":"232","author":"JI Tsao","year":"2000","unstructured":"Tsao JI, Nimura Y, Kamiya J, et al. Management of hilar cholangiocarcinoma: comparison of an American and a Japanese experience. Ann Surg. 2000;232(2):166.","journal-title":"Ann Surg"},{"issue":"4","key":"17075_CR2","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1080\/13651820500373093","volume":"7","author":"AA Parikh","year":"2005","unstructured":"Parikh AA, Abdalla EK, Vauthey JN. Operative considerations in resection of hilar cholangiocarcinoma. HPB (Oxford). 2005;7(4):254\u20138.","journal-title":"HPB (Oxford)"},{"issue":"5","key":"17075_CR3","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1007\/s00268-012-1497-0","volume":"36","author":"AW Kow","year":"2012","unstructured":"Kow AW, Wook CD, Song SC, et al. Role of caudate lobectomy in type III A and III B hilar cholangiocarcinoma: a 15-year experience in a tertiary institution. World J Surg. 2012;36(5):1112\u201321.","journal-title":"World J Surg"},{"issue":"2","key":"17075_CR4","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/nrclinonc.2017.157","volume":"15","author":"S Rizvi","year":"2018","unstructured":"Rizvi S, Khan SA, Hallemeier CL, Kelley RK, Gores GJ. Cholangiocarcinoma\u2014evolving concepts and therapeutic strategies. Nat Rev Clin Oncol. 2018;15(2):95\u2013111.","journal-title":"Nat Rev Clin Oncol"},{"issue":"15","key":"17075_CR5","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.3748\/wjg.15.1892","volume":"15","author":"Z Shi","year":"2009","unstructured":"Shi Z, Yang MZ, He QL, Ou RW, Chen YT. Addition of hepatectomy decreases liver recurrence and leads to long survival in hilar cholangiocarcinoma. World J Gastroenterol. 2009;15(15):1892\u20136.","journal-title":"World J Gastroenterol"},{"issue":"4","key":"17075_CR6","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1080\/13651820500372376","volume":"7","author":"S Dinant","year":"2005","unstructured":"Dinant S, Gerhards MF, Busch OR, Obertop H, Gouma DJ, Van Gulik TM. The importance of complete excision of the caudate lobe in resection of hilar cholangiocarcinoma. HPB (Oxford). 2005;7(4):263\u20137.","journal-title":"HPB (Oxford)"},{"issue":"2","key":"17075_CR7","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1097\/SLA.0b013e31817f2bfd","volume":"248","author":"F Ito","year":"2008","unstructured":"Ito F, Agni R, Rettammel RJ, et al. Resection of hilar cholangiocarcinoma: concomitant liver resection decreases hepatic recurrence. Ann Surg. 2008;248(2):273\u20139.","journal-title":"Ann Surg"},{"issue":"2","key":"17075_CR8","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/j.1477-2574.2010.00262.x","volume":"13","author":"A Chauhan","year":"2011","unstructured":"Chauhan A, House MG, Pitt HA, et al. Post-operative morbidity results in decreased long-term survival after resection for hilar cholangiocarcinoma. HPB (Oxford). 2011;13(2):139\u201347.","journal-title":"HPB (Oxford)"},{"issue":"5","key":"17075_CR9","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1093\/bjs\/znad057","volume":"110","author":"AM van Keulen","year":"2023","unstructured":"van Keulen AM, Buettner S, Erdmann JI, et al. Multivariable prediction model for both 90-day mortality and long-term survival for individual patients with perihilar cholangiocarcinoma: does the predicted survival justify the surgical risk? Br J Surg. 2023;110(5):599\u2013605.","journal-title":"Br J Surg"},{"issue":"3","key":"17075_CR10","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.jamcollsurg.2017.06.007","volume":"225","author":"PB Olthof","year":"2017","unstructured":"Olthof PB, Wiggers JK, Groot Koerkamp B, et al. Postoperative liver failure risk score: identifying patients with resectable perihilar cholangiocarcinoma who can benefit from portal vein embolization. J Am Coll Surg. 2017;225(3):387\u201394.","journal-title":"J Am Coll Surg"},{"issue":"2","key":"17075_CR11","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1080\/13651820801992666","volume":"10","author":"Y Nimura","year":"2008","unstructured":"Nimura Y. Preoperative biliary drainage before resection for cholangiocarcinoma (Pro). HPB (Oxford). 2008;10(2):130\u20133.","journal-title":"HPB (Oxford)"},{"issue":"2","key":"17075_CR12","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1111\/j.1477-2574.2011.00419.x","volume":"14","author":"RM Cannon","year":"2012","unstructured":"Cannon RM, Brock G, Buell JF. Surgical resection for hilar cholangiocarcinoma: experience improves resectability. HPB (Oxford). 2012;14(2):142\u20139.","journal-title":"HPB (Oxford)"},{"issue":"5","key":"17075_CR13","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1111\/j.1477-2574.2009.00090.x","volume":"11","author":"TJ Kennedy","year":"2009","unstructured":"Kennedy TJ, Yopp A, Qin Y, et al. Role of preoperative biliary drainage of liver remnant prior to extended liver resection for hilar cholangiocarcinoma. HPB (Oxford). 2009;11(5):445\u201351.","journal-title":"HPB (Oxford)"},{"issue":"2","key":"17075_CR14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.jamcollsurg.2016.03.035","volume":"223","author":"JK Wiggers","year":"2016","unstructured":"Wiggers JK, Groot Koerkamp B, Cieslak KP, et al. Postoperative mortality after liver resection for perihilar cholangiocarcinoma: development of a risk score and importance of biliary drainage of the future liver remnant. J Am Coll Surg. 2016;223(2):321-331e1.","journal-title":"J Am Coll Surg"},{"issue":"1","key":"17075_CR15","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.jamcollsurg.2016.01.060","volume":"223","author":"D Ribero","year":"2016","unstructured":"Ribero D, Zimmitti G, Aloia TA, et al. Preoperative cholangitis and future liver remnant volume determine the risk of liver failure in patients undergoing resection for hilar cholangiocarcinoma. J Am Coll Surg. 2016;223(1):87\u201397.","journal-title":"J Am Coll Surg"},{"issue":"2","key":"17075_CR16","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1002\/bjs.8950","volume":"100","author":"O Farges","year":"2013","unstructured":"Farges O, Regimbeau JM, Fuks D, et al. Multicentre European study of preoperative biliary drainage for hilar cholangiocarcinoma. Br J Surg. 2013;100(2):274\u201383.","journal-title":"Br J Surg"},{"issue":"1","key":"17075_CR17","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1097\/SLA.0000000000004534","volume":"274","author":"M Nagino","year":"2021","unstructured":"Nagino M, Ebata T, Mizuno T. Oncological superiority of right-sided hepatectomy over left-sided hepatectomy as surgery for perihilar cholangiocarcinoma: truth or biased view? Ann Surg. 2021;274(1):31\u20132.","journal-title":"Ann Surg"},{"issue":"6","key":"17075_CR18","doi-asserted-by":"publisher","first-page":"e638","DOI":"10.1097\/SLA.0000000000005201","volume":"274","author":"M Nagino","year":"2021","unstructured":"Nagino M. Left hepatic trisectionectomy with caudate lobectomy: demanding but essential routine surgical procedure for perihilar cholangiocarcinoma. Ann Surg. 2021;274(6):e638\u201340.","journal-title":"Ann Surg"},{"issue":"5","key":"17075_CR19","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1067\/msy.2000.105294","volume":"127","author":"JN Vauthey","year":"2000","unstructured":"Vauthey JN, Chaoui A, Do KA, et al. Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associations. Surgery. 2000;127(5):512\u20139.","journal-title":"Surgery"},{"issue":"2","key":"17075_CR20","first-page":"170","volume":"140","author":"H Bismuth","year":"1975","unstructured":"Bismuth H, Corlette MB. Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver. Surg Gynecol Obstet. 1975;140(2):170\u20138.","journal-title":"Surg Gynecol Obstet"},{"issue":"1","key":"17075_CR21","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s00534-012-0561-3","volume":"20","author":"S Kiriyama","year":"2013","unstructured":"Kiriyama S, Takada T, Strasberg SM, et al. TG13 guidelines for diagnosis and severity grading of acute cholangitis (with videos). J Hepatobiliary Pancreat Sci. 2013;20(1):24\u201334.","journal-title":"J Hepatobiliary Pancreat Sci"},{"issue":"2","key":"17075_CR22","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","volume":"240","author":"D Dindo","year":"2004","unstructured":"Dindo D, Demartines N, Clavien P-A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205.","journal-title":"Ann Surg"},{"issue":"5","key":"17075_CR23","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.jamcollsurg.2006.12.032","volume":"204","author":"JT Mullen","year":"2007","unstructured":"Mullen JT, Ribero D, Reddy SK, et al. Hepatic insufficiency and mortality in 1059 noncirrhotic patients undergoing major hepatectomy. J Am Coll Surg. 2007;204(5):854\u201362.","journal-title":"J Am Coll Surg"},{"issue":"5","key":"17075_CR24","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.surg.2010.10.001","volume":"149","author":"NN Rahbari","year":"2011","unstructured":"Rahbari NN, Garden OJ, Padbury R, et al. Posthepatectomy liver failure: a definition and grading by the International study group of liver surgery (ISGLS). Surgery. 2011;149(5):713\u201324.","journal-title":"Surgery"},{"issue":"5","key":"17075_CR25","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1097\/SLA.0000000000005103","volume":"274","author":"M Mueller","year":"2021","unstructured":"Mueller M, Breuer E, Mizuno T, et al. Perihilar cholangiocarcinoma\u2014novel benchmark values for surgical and oncological outcomes from 24 expert centers. Ann Surg. 2021;274(5):780\u20138.","journal-title":"Ann Surg"},{"issue":"5","key":"17075_CR26","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/S1072-7515(02)01481-3","volume":"195","author":"L Capussotti","year":"2002","unstructured":"Capussotti L, Muratore A, Polastri R, Ferrero A, Massucco P. Liver resection for hilar cholangiocarcinoma: in-hospital mortality and longterm survival. J Am Coll Surg. 2002;195(5):641\u20137.","journal-title":"J Am Coll Surg"},{"issue":"4","key":"17075_CR27","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s00534-009-0209-0","volume":"17","author":"T Igami","year":"2010","unstructured":"Igami T, Nishio H, Ebata T, et al. Surgical treatment of hilar cholangiocarcinoma in the \u201cnew era\u201d: the Nagoya University experience. J Hepato Pancreat Sci. 2010;17(4):449\u201354.","journal-title":"J Hepato Pancreat Sci"},{"issue":"5","key":"17075_CR28","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1001\/archsurg.139.5.514","volume":"139","author":"DJ Rea","year":"2004","unstructured":"Rea DJ, Munoz-Juarez M, Farnell MB, et al. Major hepatic resection for hilar cholangiocarcinoma: analysis of 46 patients. Arch Surg. 2004;139(5):514\u201323.","journal-title":"Arch Surg"},{"issue":"10","key":"17075_CR29","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.3748\/wjg.v13.i10.1505","volume":"13","author":"Y Seyama","year":"2007","unstructured":"Seyama Y, Makuuchi M. Current surgical treatment for bile duct cancer. World J Gastroenterol. 2007;13(10):1505\u201315.","journal-title":"World J Gastroenterol"},{"issue":"4","key":"17075_CR30","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1007\/s00534-009-0203-6","volume":"17","author":"AL Young","year":"2010","unstructured":"Young AL, Prasad KR, Toogood GJ, Lodge JP. Surgical treatment of hilar cholangiocarcinoma in a new era: comparison among leading Eastern and Western centers, Leeds. J Hepato Pancreat Sci. 2010;17(4):497\u2013504.","journal-title":"J Hepato Pancreat Sci"},{"issue":"1","key":"17075_CR31","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1001\/archsurg.2011.771","volume":"147","author":"G Nuzzo","year":"2012","unstructured":"Nuzzo G, Giuliante F, Ardito F, et al. Improvement in perioperative and long-term outcome after surgical treatment of hilar cholangiocarcinoma: results of an Italian multicenter analysis of 440 patients. Arch Surg. 2012;147(1):26\u201334.","journal-title":"Arch Surg"},{"issue":"8","key":"17075_CR32","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/hpb.12450","volume":"17","author":"JC Mansour","year":"2015","unstructured":"Mansour JC, Aloia TA, Crane CH, Heimbach JK, Nagino M, Vauthey J-N. Hilar cholangiocarcinoma: expert consensus statement. HPB. 2015;17(8):691\u20139.","journal-title":"HPB"},{"issue":"2","key":"17075_CR33","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.soc.2008.12.007","volume":"18","author":"M Palavecino","year":"2009","unstructured":"Palavecino M, Abdalla EK, Madoff DC, Vauthey JN. Portal vein embolization in hilar cholangiocarcinoma. Surg Oncol Clin N Am. 2009;18(2):257\u201367.","journal-title":"Surg Oncol Clin N Am"},{"issue":"3","key":"17075_CR34","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/s00423-003-0383-5","volume":"388","author":"P Neuhaus","year":"2003","unstructured":"Neuhaus P, Jonas S, Settmacher U, et al. Surgical management of proximal bile duct cancer: extended right lobe resection increases resectability and radicality. Langenbecks Arch Surg. 2003;388(3):194\u2013200.","journal-title":"Langenbecks Arch Surg"},{"issue":"6","key":"17075_CR35","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1097\/00000658-199912000-00010","volume":"230","author":"P Neuhaus","year":"1999","unstructured":"Neuhaus P, Jonas S, Bechstein WO, et al. Extended resections for hilar cholangiocarcinoma. Ann Surg. 1999;230(6):808\u201318.","journal-title":"Ann Surg"},{"issue":"2","key":"17075_CR36","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1097\/01.sla.0000171304.70678.11","volume":"242","author":"H Nishio","year":"2005","unstructured":"Nishio H, Hidalgo E, Hamady ZZ, et al. Left hepatic trisectionectomy for hepatobiliary malignancy: results and an appraisal of its current role. Ann Surg. 2005;242(2):267\u201375.","journal-title":"Ann Surg"},{"issue":"1","key":"17075_CR37","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1097\/SLA.0000000000004821","volume":"274","author":"H Lang","year":"2021","unstructured":"Lang H, van Gulik TM. Extended right-hemihepatectomy is preferred for perihilar cholangiocarcinoma. Ann Surg. 2021;274(1):33\u20134.","journal-title":"Ann Surg"},{"issue":"7","key":"17075_CR38","doi-asserted-by":"publisher","first-page":"4405","DOI":"10.1245\/s10434-024-15115-0","volume":"31","author":"PB Olthof","year":"2024","unstructured":"Olthof PB, Erdmann JI, Alikhanov R, et al. Higher postoperative mortality and inferior survival after right-sided liver resection for perihilar cholangiocarcinoma: left-sided resection is preferred when possible. Ann Surg Oncol. 2024;31(7):4405\u201312.","journal-title":"Ann Surg Oncol"}],"container-title":["Annals of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-025-17075-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1245\/s10434-025-17075-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1245\/s10434-025-17075-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T16:14:14Z","timestamp":1746288854000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1245\/s10434-025-17075-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,25]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["17075"],"URL":"https:\/\/doi.org\/10.1245\/s10434-025-17075-5","relation":{},"ISSN":["1068-9265","1534-4681"],"issn-type":[{"value":"1068-9265","type":"print"},{"value":"1534-4681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,25]]},"assertion":[{"value":"11 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Consulting or advisory Role: Zymeworks, Ipsen, Novartis, Janssen, AskGene Pharma, BPGBio, Jazz Pharmaceuticals, AstraZeneca, Boehringer Ingelheim, USWorldmeds, Nihon Medi-Physics Co, Ltd, Alligator Bioscience, Revolution Medicine, Theriva Biosciences, Arcus, BMS, Merck, Pfizer. Research funding (funding to institution): Mirati Therapeutics, Lilly, Novartis, Bristol-Myers Squibb, Astellas, Framewave, Boehringer Ingelheim, NGM Pharmaceuticals, Janssen, Arcus, Elicio, Biontech, Ipsen, Zymeworks, Pfizer, ImmunoMET, Immuneering, Amal Therapeutics, Jazz Therapeutics, Revolution medicine. Stock: Telperian","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}}]}}