{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:40:06Z","timestamp":1783528806953,"version":"3.55.0"},"reference-count":16,"publisher":"Pharmaceutical Society of Japan","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological & Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2002]]},"DOI":"10.1248\/bpb.25.523","type":"journal-article","created":{"date-parts":[[2002,8,26]],"date-time":"2002-08-26T16:58:55Z","timestamp":1030381135000},"page":"523-525","source":"Crossref","is-referenced-by-count":48,"title":["Effects of Kangen-karyu on Coagulation System and Platelet Aggregation in Mice."],"prefix":"10.1248","volume":"25","author":[{"given":"Toshiaki","family":"Makino","sequence":"first","affiliation":[{"name":"Department of Kampo Medicinal Science, Hokkaido College of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannosuke","family":"Wakushima","sequence":"additional","affiliation":[{"name":"Department of Kampo Medicinal Science, Hokkaido College of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Kampo Medicinal Science, Hokkaido College of Pharmacy"},{"name":"Iskura Industry Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Okukubo","sequence":"additional","affiliation":[{"name":"Iskura Industry Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Kampo Medicinal Science, Hokkaido College of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Kano","sequence":"additional","affiliation":[{"name":"Department of Kampo Medicinal Science, Hokkaido College of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","unstructured":"1) Bensky D., Barolet R., “Chinese Herbal Medicine—Formulas & Strategies,” Eastland Press, Washington, 1990."},{"key":"2","first-page":"145","volume":"12","author":"Takahashi H.","year":"1991","journal-title":"Clin. J. Chinese Med.","ISSN":"https:\/\/id.crossref.org\/issn\/1749-8546","issn-type":"print"},{"key":"3","first-page":"667","volume":"3","author":"Tanaka N.","year":"1993","journal-title":"Clin. Pharm. Ther.","ISSN":"https:\/\/id.crossref.org\/issn\/0278-2677","issn-type":"print"},{"issue":"3","key":"4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1254\/jjp.60.307","volume":"60","author":"TAKAHASHI M","year":"1992","journal-title":"Jpn. J. Pharmacol.","ISSN":"https:\/\/id.crossref.org\/issn\/0021-5198","issn-type":"print"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/0090-6980(81)90230-6"},{"key":"6","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/clinchem\/46.8.1260","volume":"46","author":"Triplett D. A.","year":"2000","journal-title":"Clin. Chem."},{"issue":"1","key":"7","first-page":"57","volume":"225","author":"DiMinno G., Silver M.","year":"1983","journal-title":"J. Pharmacol. Exp. Ther.","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"key":"8","unstructured":"8) DeFeudis F., “Ginkgo biloba<\/i> Extract (EGb761),” Elsevier, Paris, 1991."},{"issue":"11","key":"9","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1093\/jn\/130.11.2662","volume":"130","author":"RAHMAN K","year":"2000","journal-title":"J. Nutr.","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3166","issn-type":"print"},{"key":"10","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1055\/s-0038-1657286","volume":"48","author":"Wang Z., Roberts J., Grant P., Colm","year":"1982","journal-title":"Thromb. Haemost.","ISSN":"https:\/\/id.crossref.org\/issn\/0340-6245","issn-type":"print"},{"key":"11","first-page":"859","volume":"21","author":"Wang W., Wang Y. P., Sun W. K., Xu","year":"2000","journal-title":"Acta Pharmacologica Sinica","ISSN":"https:\/\/id.crossref.org\/issn\/1671-4083","issn-type":"print"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1248\/yakushi1947.103.3_313","volume":"103","author":"Terasawa K., Kimura M., Sakurakawa","year":"1983","journal-title":"Yakugaku Zasshi","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6903","issn-type":"print"},{"key":"13","first-page":"1","volume":"15","author":"Kobashi K.","year":"1998","journal-title":"J. Trad. Med.","ISSN":"https:\/\/id.crossref.org\/issn\/1880-1447","issn-type":"print"},{"issue":"7","key":"14","first-page":"603","volume":"11","year":"1992","journal-title":"Clin. Pharm.","ISSN":"https:\/\/id.crossref.org\/issn\/0278-2677","issn-type":"print"},{"issue":"4","key":"15","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1345\/aph.19029","volume":"35","author":"CHAN T Y K","year":"2001","journal-title":"Ann. Pharmacother.","ISSN":"https:\/\/id.crossref.org\/issn\/1060-0280","issn-type":"print"},{"key":"16","first-page":"241","volume":"28","author":"Zou Z. W., Xu L. N., Tian J. Y.","year":"1993","journal-title":"Acta Pharmaceutica Sinica","ISSN":"https:\/\/id.crossref.org\/issn\/0003-2670","issn-type":"print"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/bpb\/25\/4\/25_4_523\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T05:42:04Z","timestamp":1614145324000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/bpb\/25\/4\/25_4_523\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.25.523","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}