{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:11:03Z","timestamp":1780103463090,"version":"3.54.0"},"reference-count":37,"publisher":"Pharmaceutical Society of Japan","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2012]]},"DOI":"10.1248\/bpb.35.280","type":"journal-article","created":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T06:11:48Z","timestamp":1330582308000},"page":"280-288","source":"Crossref","is-referenced-by-count":20,"title":["Site-Specific Chemical Modification of Human Serum Albumin with Polyethylene Glycol Prolongs Half-life and Improves Intravascular Retention in Mice"],"prefix":"10.1248","volume":"35","author":[{"given":"Ting","family":"Zhao","sequence":"first","affiliation":[{"name":"Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Na","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmaceutical Sciences, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Ning","family":"Tan","sequence":"additional","affiliation":[{"name":"National Glycoengineering Research Center, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan-Li","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Li","family":"Pang","sequence":"additional","affiliation":[{"name":"Shandong Taibang Biological Products Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Shan","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University"},{"name":"National Glycoengineering Research Center, Shandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"issue":"15","key":"1","doi-asserted-by":"crossref","first-page":"6747","DOI":"10.1016\/S0021-9258(19)62680-3","volume":"261","author":"Mingetti, P.P., Ruffner, D.E., Kuan","year":"1986","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1994.00363.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Doweiko JP, Nompleggi DJ. Role of albumin in human physiology and pathophysiology. <i>JPEN J. Parenter. Enteral Nutr.<\/i>, <b>15<\/b>, 207&#8212;211 (1991).","DOI":"10.1177\/0148607191015002207"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Kobayashi K. Summary of recombinant human serum albumin development. <i>Biologicals<\/i>, <b>34<\/b>, 55&#8212;59 (2006).","DOI":"10.1016\/j.biologicals.2005.08.021"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Christ F, Gamble J, Gartside IB, Kox WJ. Increased microvascular water permeability in patients with septic shock, assessed with venous congestion plethysmography (VCP). <i>Intensive Care Med.<\/i>, <b>24<\/b>, 18&#8212;27 (1998).","DOI":"10.1007\/s001340050509"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. <i>Br. J. Anaesth.<\/i>, <b>85<\/b>, 599&#8212;610 (2000).","DOI":"10.1093\/bja\/85.4.599"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1017\/S0265021503000681"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-006-9933-1"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1021\/bc970082p"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7799(00)88912-X"},{"key":"11","unstructured":"11) Li JW, Xiao NG, Yu RY, Yuan MX, Chen LR, Chen YH, Chen LT. <i>Experimental Principles and Methods of Biochemistry<\/i>. Peking University Publishers, Beijing (2000)."},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(92)90460-O"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Cantin AM, Woods DE, Cloutier D, Dufour EK, Leduc R. Polyethylene glycol conjugation at Cys232 prolongs the half-life of alpha1 proteinase inhibitor. <i>Am. J. Respir. Cell Mol. Biol.<\/i>, <b>27<\/b>, 659&#8212;665 (2002).","DOI":"10.1165\/rcmb.4866"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1021\/ma00090a007"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(78)91322-0"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Cho HM, Rosenblatt JD, Kang YS, Iruela-Arispe ML, Morrison SL, Penichet ML, Kwon YG, Kim TW, Webster KA, Nechustan H, Shin SU. Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein. <i>Mol. Cancer Ther.<\/i>, <b>4<\/b>, 956&#8212;967 (2005).","DOI":"10.1158\/1535-7163.MCT-04-0321"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2010.09.008"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Monsigny M, Roche AC, Midoux P. Uptake of neoglycoproteins <i>via<\/i> membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting. <i>Biol. Cell<\/i>, <b>51<\/b>, 187&#8212;196 (1984).","DOI":"10.1111\/j.1768-322X.1984.tb00298.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(96)00236-0"},{"issue":"3","key":"20","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S0022-3565(24)39169-4","volume":"294","author":"ANDO H","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1021\/bm100578c"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(05)03575-0"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.33.1540"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.33.1253"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2008.02.021"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1021\/bc050322y"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2004.04474.x"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Dubniks M, Persson J, Gr&auml;nde PO. Effect of blood pressure on plasma volume loss in the rat under increased permeability. <i>Intensive Care Med.<\/i>, <b>33<\/b>, 2192&#8212;2198 (2007).","DOI":"10.1007\/s00134-007-0756-2"},{"key":"29","unstructured":"29) Haupt MT, Gilbert EM, Carlson RW. Fluid loading increases oxygen consumption in septic patients with lactic acidosis. <i>Am. Rev. Respir. Dis.<\/i>, <b>131<\/b>, 912&#8212;916 (1985)."},{"key":"30","unstructured":"30) Rippe B, Haraldsson B. Transport of macromolecules across microvascular walls: the two-pore theory. <i>Physiol. Rev.<\/i>, <b>74<\/b>, 163&#8212;219 (1994)."},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Sejrsen P, Paaske WP, Henriksen O. Capillary permeability of 131I-albumin in skeletal muscle. <i>Microvasc. Res.<\/i>, <b>29<\/b>, 265&#8212;281 (1985).","DOI":"10.1016\/0026-2862(85)90018-4"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) McCurdy TR, Gataiance S, Eltringham-Smith LJ, Sheffield WP. A covalently linked recombinant albumin dimer is more rapidly cleared <i>in vivo<\/i> than are wild-type and mutant C34A albumin. <i>J. Lab. Clin. Med.<\/i>, <b>143<\/b>, 115&#8212;124 (2004).","DOI":"10.1016\/j.lab.2003.10.008"},{"issue":"10","key":"33","doi-asserted-by":"crossref","first-page":"7562","DOI":"10.1016\/S0021-9258(18)53212-9","volume":"268","year":"1993","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"34","unstructured":"34) Fleck A, Raines G, Hawker F, Trotter J, Wallace PI, Ledingham IM, Calman KC. Increased vascular permeability: a major cause of hypoalbuminaemia in disease and injury. <i>Lancet<\/i>, <b>1<\/b>, 781&#8212;784 (1985)."},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Manelli JC. Is albumin administration useful in critical care for burnt patients? <i>Ann. Fr. Anesth. Reanim.<\/i>, <b>15<\/b>, 507&#8212;513 (1996).","DOI":"10.1016\/0750-7658(96)83213-8"},{"key":"36","unstructured":"36) Groeneveld AB, Bronsveld W, Thijs LG. Hemodynamic determinants of mortality in human septic shock. <i>Surgery<\/i>, <b>99<\/b>, 140&#8212;153 (1986)."},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Traber DL. Microvascular leakage in sepsis. <i>Crit. Care Med.<\/i>, <b>28<\/b>, 882&#8212;883 (2000).","DOI":"10.1097\/00003246-200003000-00046"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/bpb\/35\/3\/35_3_280\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T07:10:53Z","timestamp":1742627453000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/bpb\/35\/3\/35_3_280\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.35.280","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}