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Histamine H2-receptor antagonists in peptic ulcer disease. Evidence for a prophylactic use. Drugs<\/i>, 47, 862\u2013871 (1994).","DOI":"10.2165\/00003495-199447060-00002"},{"key":"2","unstructured":"2) Shay H, Komarov SA, Fels SS, Meranze D. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology<\/i>, 4, 43\u201361 (1945)."},{"key":"3","unstructured":"3) Kusters JG, van Vliet AH, Kuipers EJ. Pathogenesis of Helicobacter pylori<\/i> infection. Clin. Microbiol. Rev.<\/i>, 19, 449\u2013490 (2006)."},{"key":"4","unstructured":"4) Lin HC, Ding HY, Wu YC. Two novel compounds from Paeonia suffructicosa<\/i>. J. Nat. Prod.<\/i>, 61, 343\u2013346 (1998)."},{"key":"5","unstructured":"5) Oh GS, Pae HO, Choi BM, Jeong S, Oh H, Oh CS, Rho YD, Kim DH, Shin MK, Chung HT. Inhibitory effects of the root cortex of Paeonia suffruticosa<\/i> on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. J. Ethnopharmacol.<\/i>, 84, 85\u201389 (2003)."},{"key":"6","unstructured":"6) Hsiang CY, Hsieh CL, Wu SL, Lai IL, Ho TY. Inhibitory effect of anti-pyretic and anti-inflammatory herbs on herpes simplex virus replication. Am. J. Chin. Med.<\/i>, 29, 459\u2013467 (2001)."},{"key":"7","unstructured":"7) Au TK, Lam TL, Ng TB, Fong WP, Wan DC. A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. Life Sci.<\/i>, 68, 1687\u20131694 (2001)."},{"key":"8","unstructured":"8) Jeong SJ, Ahn NH, Kim YC. Hyaluronidase inhibitors from moutan cortex radicis. Kor. J. Pharmacogn.<\/i>, 29, 44\u201347 (1998)."},{"key":"9","unstructured":"9) Kwon OG, Kim SH, Chun BY, Park CK, Son KH. Isolation of antimicrobial components from moutan cortex. Kor. J. Pharmacogn.<\/i>, 30, 340\u2013344 (1999)."},{"key":"10","unstructured":"10) Lee SH, Park JS, Kim SY, Kim JJ, Chung SR. Isolation of inhibitory on tyrosinase activity from the bark of Paeonia moutan<\/i>. Yakhak Hoeji<\/i>, 42, 353\u2013358 (1998)."},{"key":"11","unstructured":"11) Okubo T, Nagai F, Seto T, Satoh K, Ushiyama K, Kano I. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. Biol. Pharm. Bull.<\/i>, 23, 199\u2013203 (2000)."},{"key":"12","unstructured":"12) Murakami N, Saka M, Shimada H, Matsuda H, Yamahara J, Yoshikawa M. New bioactive monoterpene glycosides from Paeoniae Radix. Chem. Pharm. Bull.<\/i>, 44, 1279\u20131281 (1996)."},{"key":"13","unstructured":"13) Kitakawa T, Yoshikawa M, Tsunaga K, Tani T. Studies on moutan cortex (II) on the chemical constituents. Shoyakugaku Zasshi<\/i>, 33, 171\u2013179 (1979)."},{"key":"14","unstructured":"14) Ding HY, Wu YC, Lin HC, Chan YY, Wu PL, Wu TS. Glycosides from Paeonia suffruticosa<\/i>. Chem. Pharm. Bull.<\/i>, 47, 652\u2013655 (1999)."},{"key":"15","unstructured":"15) Kariyone T, Hayashi K. Studies on the microanalysis of essential oil components. I. The paper chromatography of terpene alcohol by using anthranilate. Pharm. Bull.<\/i>, 4, 494\u2013495 (1956)."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Jung J, Lee JH, Bae KH, Jeong CS. Jung J, Lee JH, Bae KH, Jeong CS. Anti-gastric actions of eugenol and cinnamic acid isolated from Cinnamomi Ramulus. Yakugaku Zasshi<\/i>, 131, 1103\u20131110 (2011).","DOI":"10.1248\/yakushi.131.1103"},{"key":"17","unstructured":"17) Santra A, Chowdhury A, Chaudhury S, Das Gupta J, Banerjee PK, Mazumder DN. Oxidative stress in gastric mucosa in Helicobacter pylori<\/i> infection. Indian J. Gastroenterol.<\/i>, 19, 21\u201323 (2000)."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Leirisalo-Repo M, Paimela L, Koskimies S, Repo H. Functions of polymorphonuclear leukocytes in early rheumatoid arthritis. Inflammation<\/i>, 17, 427\u2013442 (1993).","DOI":"10.1007\/BF00916583"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Mobley HLT. Urease. Helicobacter pylori<\/i>; Physiology and genetics. (Mobley HLT, Medz GL, Hazeli SL eds.) ASM press, Washington, chapter 16 (2001).","DOI":"10.1128\/9781555818005"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Marshall BJ, Goodwin CS, Warren JR, Murray R, Blincow ED, Blackbourn SJ, Phillips M, Waters TE, Sanderson CR. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori<\/i>. Lancer<\/i> 2<\/b>(8628\u20138627), 1437\u20131442 (1988).","DOI":"10.1016\/S0140-6736(88)90929-4"},{"key":"21","unstructured":"21) Bae EA, Han MJ, Kim DH. In vitro<\/i> anti-Helicobacter pylori<\/i> activity of some flavonoids and their metabolites. Planta Med.<\/i>, 65, 442\u2013443 (1999)."},{"key":"22","unstructured":"22) Njume C, Afolayan AJ, Ndip RN. Preliminary phytochemical screening and in vitro<\/i> anti-Helicobacter pylori<\/i> activity of acetone and aqueous extracts of the stem bark of Sclerocarya birrea<\/i> (Anacardiaceae). Arch. Med. 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