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Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. <i>N. Engl. J. Med.<\/i>, 354, 2542\u20132551 (2006)."},{"key":"2","unstructured":"2) Cohen MH, Williams G, Johnson JR, Duan J, Gobburu J, Rahman A, Benson K, Leighton J, Kim SK, Wood R, Rothmann M, Chen G, U KM, Staten AM, Pazdur R. U KM, Staten AM, Pazdur R. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. <i>Clin. Cancer Res.<\/i>, 8, 935\u2013942 (2002)."},{"key":"3","unstructured":"3) Melo JV, Chuah C. Resistance to imatinib mesylate in chronic myeloid leukaemia. <i>Cancer Lett.<\/i>, 249, 121\u2013132 (2007)."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) von Bubnoff N, Manley PW, Mestan J, Sanger J, Peschel C, Duyster J. Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107). <i>Blood<\/i>, 108, 1328\u20131333 (2006).","DOI":"10.1182\/blood-2005-12-010132"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Weisberg E, Manley PW, Breitenstein W, Bruggen J, Cowan-Jacob SW, Ray A, Huntly B, Fabbro D, Fendrich G, Hall-Meyers E, Kung AL, Mestan J, Daley GQ, Callahan L, Catley L, Cavazza C, Azam M, Neuberg D, Wright RD, Gilliland DG, Griffin JD. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. <i>Cancer Cell<\/i>, 7, 129\u2013141 (2005).","DOI":"10.1016\/j.ccr.2005.01.007"},{"key":"6","unstructured":"6) Saglio G, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Lobo C, Pasquini R, Clark RE, Hochhaus A, Hughes TP, Gallagher N, Hoenekopp A, Dong M, Haque A, Larson RA, Kantarjian HM, ENESTnd Investigators. 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