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The absence of accessible vitronectin receptors in differentiated tissue hinders adenoviral-mediated gene transfer to the intestinal epithelium <i>in vitro.<\/i> <i>Pharm. Res.<\/i>, <b>14<\/b>, 1216\u20131222 (1997).","DOI":"10.1023\/A:1012163025455"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW. F. R. W. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. <i>Science<\/i>, <b>275<\/b>, 1320\u20131323 (1997).","DOI":"10.1126\/science.275.5304.1320"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Bai M, Harfe B, Freimuth P. Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells. <i>J. Virol.<\/i>, <b>67<\/b>, 5198\u20135205 (1993).","DOI":"10.1128\/JVI.67.9.5198-5205.1993"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Wickham TJ, Mathias P, Cheresh DA, Nemerow GR. Integrins \u03b1v\u03b23 and \u03b1v\u03b25 promote adenovirus internalization but not virus attachment. <i>Cell<\/i>, <b>73<\/b>, 309\u2013319 (1993).","DOI":"10.1016\/0092-8674(93)90231-E"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Grotz N, Fox T, Connolly E, Park W, Guerinot ML, Eide D. Identification of a family of zinc transporter genes from <i>Arabidopsis<\/i> that respond to zinc deficiency. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>95<\/b>, 7220\u20137224 (1998).","DOI":"10.1073\/pnas.95.12.7220"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Zabner J, Freimuth P, Puga A, Fabrega A, Welsh MJ. Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection. <i>J. Clin. 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Virol.<\/i>, <b>77<\/b>, 13062\u201313072 (2003).","DOI":"10.1128\/JVI.77.24.13062-13072.2003"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Koizumi N, Kawabata K, Sakurai F, Watanabe Y, Hayakawa T, Mizuguchi H. Modified adenoviral vectors ablated for coxsackievirus-adenovirus receptor, alpha v integrin, and heparan sulfate binding reduce <i>in vivo<\/i> tissue transduction and toxicity. <i>Hum. Gene Ther.<\/i>, <b>17<\/b>, 264\u2013279 (2006).","DOI":"10.1089\/hum.2006.17.264"},{"key":"12","unstructured":"12) Maizel JV Jr, White DO, Scharff MD. The polypeptides of adenovirus: I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. <i>Virology<\/i>, <b>36<\/b>, 115\u2013125 (1968)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Kesisoglou F, Schmiedlin-ren P, Fleisher D, Roessler B, Zimmermann EM. Restituting intestinal epithelial cells exhibit increased transducibility by adenoviral vectors. <i>J. 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