{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T12:33:15Z","timestamp":1723120395427},"reference-count":38,"publisher":"Pharmaceutical Society of Japan","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2015]]},"DOI":"10.1248\/bpb.b15-00375","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T18:01:17Z","timestamp":1443636077000},"page":"1580-1590","source":"Crossref","is-referenced-by-count":5,"title":["Excessive Interleukin 18 Relate the Aggravation of Indomethacin-Induced Intestinal Ulcerogenic Lesions in Adjuvant-Induced Arthritis Rat"],"prefix":"10.1248","volume":"38","author":[{"given":"Noriaki","family":"Nagai","sequence":"first","affiliation":[{"name":"Faculty of Pharmacy, Kinki University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadatoshi","family":"Tanino","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences, Tokushima Bunri University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimasa","family":"Ito","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Kinki University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Hultqvist M, Olofsson P, Gelderman KA, Holmberg J, Holmdahl R. A new arthritis therapy with oxidative burst inducers. <i>PLoS Med.<\/i>, <b>3<\/b>, e348 (2006).","DOI":"10.1371\/journal.pmed.0030348"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Escandell JM, Recio MC, Manez S, Giner RM, Cerda-Nicolas M, Rios JL. Cucurbitacin R reduces the inflammation and bone damage associated with adjuvant arthritis in lewis rats by suppression of tumor necrosis factor-alpha in T lymphocytes and macrophages. <i>J. Pharmacol. Exp. Ther.<\/i>, <b>320<\/b>, 581\u2013590 (2007).","DOI":"10.1124\/jpet.106.107003"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Kato S, Takeuchi K. Alteration of gastric ulcerogenic and healing responses in rats with adjuvant-induced arthritis. <i>Jpn. J. Pharmacol.<\/i>, <b>89<\/b>, 1\u20136 (2002).","DOI":"10.1254\/jjp.89.1"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Fries JF, Miller SR, Spitz PW, Williams CA, Hubert HB, Bloch DA. Toward an epidemiology of gastropathy associated with nonsteroidal antiinflammatory drug use. <i>Gastroenterology<\/i>, <b>96<\/b> (Suppl), 647\u2013655 (1989).","DOI":"10.1016\/S0016-5085(89)80061-7"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Kato S, Ito Y, Nishio H, Aoi Y, Amagase K, Takeuchi K. Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis: involvement of enhanced expression of TLR4. <i>Life Sci.<\/i>, <b>81<\/b>, 1309\u20131316 (2007).","DOI":"10.1016\/j.lfs.2007.08.036"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. <i>Nat. New Biol.<\/i>, <b>231<\/b>, 232\u2013235 (1971).","DOI":"10.1038\/newbio231232a0"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Whittle BJ. Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat. <i>Gastroenterology<\/i>, <b>80<\/b>, 94\u201398 (1981).","DOI":"10.1016\/0016-5085(81)90196-7"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Weissenborn U, Maedge S, Buettner D, Sewing KF. Indomethacin-increased gastrointestinal lesions in relation to tissue concentration, food intake and bacterial invasion in the rat. <i>Pharmacology<\/i>, <b>30<\/b>, 32\u201339 (1985).","DOI":"10.1159\/000138047"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Asako H, Kubes P, Wallace J, Gaginella T, Wolf RE, Granger DN. Indomethacin-induced leukocyte adhesion in mesenteric venules; role of lipoxygenase products. <i>Am. J. Physiol.<\/i>, <b>262<\/b>, G903\u2013G908 (1992).","DOI":"10.1152\/ajpgi.1992.262.5.G903"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Yamada T, Deitch E, Specian RD, Perry MA, Sartor RB, Grisham MB. Mechanisms of acute and chronic intestinal inflammation induced by indomethacin. <i>Inflammation<\/i>, <b>17<\/b>, 641\u2013662 (1993).","DOI":"10.1007\/BF00920471"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Whittle BJ, Laszlo F, Evans SM, Moncada S. Induction of nitric oxide synthase and microvascular injury in the rat jejunum provoked by indomethacin. <i>Br. J. Pharmacol.<\/i>, <b>116<\/b>, 2286\u20132290 (1995).","DOI":"10.1111\/j.1476-5381.1995.tb15066.x"},{"key":"12","unstructured":"12) Konaka A, Nishijima M, Tanaka A, Kunikata T, Kato S, Takeuchi K. Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin induced intestinal lesions in rats. <i>Joutnsl of Pharmacology and Physiology<\/i>, <b>50<\/b>, 25\u201338 (1999)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Kato N, Mashita Y, Kato S, Mitsufuji S, Yoshikawa T, Takeuchi K. Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats <i>via<\/i> a NO\/cGMP-dependent mechanism. <i>Dig. Dis. Sci.<\/i>, <b>54<\/b>, 2346\u20132356 (2009).","DOI":"10.1007\/s10620-008-0646-7"},{"key":"14","unstructured":"14) Kato S, Ohkawa F, Ito Y, Amagase K, Takeuchi K. Role of endothelial nitric oxide synthase in aggravation of indomethacin-induced gastric damage in adjuvant arthritic rats. <i>J. Physiol. Pharmacol.<\/i>, <b>60<\/b>, 147\u2013155 (2009)."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Nagai N, Fukuhata T, Ito Y, Usui S, Hirano K. Involvement of interleukin 18 in indomethacin-induced lesions of the gastric mucosa in adjuvant-induced arthritis rat. <i>Toxicology<\/i>, <b>255<\/b>, 124\u2013130 (2009).","DOI":"10.1016\/j.tox.2008.10.005"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Billingham ME. Models of arthritis and the search for anti-arthritic drugs. <i>Pharmacol. Ther.<\/i>, <b>21<\/b>, 389\u2013428 (1983).","DOI":"10.1016\/0163-7258(83)90062-1"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Sakuma S, Nishigaki F, Magari K, Ogawa T, Miyata S, Ohkubo Y, Goto T. FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis. <i>Inflamm. Res.<\/i>, <b>50<\/b>, 509\u2013514 (2001).","DOI":"10.1007\/PL00000227"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Ghayur T, Banerjee S, Hugunin M, Butler D, Herzog L, Carter A, Quintal L, Sekut L, Talanian R, Paskind M, Wong W, Kamen R, Tracey D, Alien H. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. <i>Nature<\/i>, <b>386<\/b>, 619\u2013623 (1997).","DOI":"10.1038\/386619a0"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Gu Y, Kuida K, Tsutsui H, Ku G, Hsiao K, Fleming MA, Hayashi N, Higashino K, Okamura H, Nakanishi K, Kurimoto M, Tanimoto T, Flavell RA, Sato V, Harding MW, Livingston DJ, Su MS. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. <i>Science<\/i>, <b>275<\/b>, 206\u2013209 (1997).","DOI":"10.1126\/science.275.5297.206"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Torigoe K, Ushio S, Okura T, Kobayashi S, Taniai M, Kunikata T, Murakami T, Sanou O, Kojima H, Fujii M, Ohta T, Ikeda M, Ikegami H, Kurimoto M. Purification and characterization of the human interleukin-18 receptor. <i>J. Biol. Chem.<\/i>, <b>272<\/b>, 25737\u201325742 (1997).","DOI":"10.1074\/jbc.272.41.25737"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA, Dinarello CA. Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. <i>J. Immunol.<\/i>, <b>166<\/b>, 148\u2013154 (2001).","DOI":"10.4049\/jimmunol.166.1.148"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 regulates both Th1 and Th2 responses. <i>Annu. Rev. Immunol.<\/i>, <b>19<\/b>, 423\u2013474 (2001).","DOI":"10.1146\/annurev.immunol.19.1.423"},{"key":"23","unstructured":"23) Hoshino K, Tsutsui H, Kawai T, Takeda K, Nakanishi K, Takeda Y, Akira S. Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor. <i>J. Immunol.<\/i>, <b>162<\/b>, 5041\u20135044 (1999)."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate\u2013phenol\u2013chloroform extraction. <i>Anal. Biochem.<\/i>, <b>162<\/b>, 156\u2013159 (1987).","DOI":"10.1016\/0003-2697(87)90021-2"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein\u2013dye binding. <i>Anal. Biochem.<\/i>, <b>72<\/b>, 248\u2013254 (1976).","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Nagai N, Liu Y, Fukuhata T, Ito Y. Inhibitors of inducible nitric oxide synthase prevent damage to human lens epithelial cells induced by interferon-gamma and lipopolysaccharide. <i>Biol. Pharm. Bull.<\/i>, <b>29<\/b>, 2077\u20132081 (2006).","DOI":"10.1248\/bpb.29.2077"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Aizawa Y, Akita K, Taniai M, Torigoe K, Mori T, Nishida Y, Ushio S, Nukada Y, Tanimoto T, Ikegami H, Ikeda M, Kurimoto M. Cloning and expression of interleukin-18 binding protein. <i>FEBS Lett.<\/i>, <b>445<\/b>, 338\u2013342 (1999).","DOI":"10.1016\/S0014-5793(99)00148-9"},{"key":"28","unstructured":"28) Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. <i>Immunity<\/i>, <b>10<\/b>, 127\u2013136 (1999)."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Hurgin V, Novick D, Rubinstein M. The promoter of IL-18 binding protein: activation by an IFN-gamma-induced complex of IFN regulatory factor 1 and CCAAT\/enhancer binding protein beta. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>99<\/b>, 16957\u201316962 (2002).","DOI":"10.1073\/pnas.262663399"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Boughton-Smith N, Evans SM, Laszlo F, Whittle BJ, Moncada S. The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. <i>Br. J. Pharmacol.<\/i>, <b>110<\/b>, 1189\u20131195 (1993).","DOI":"10.1111\/j.1476-5381.1993.tb13940.x"},{"key":"31","unstructured":"31) Tanaka A, Kunikata T, Mizoguchi H, Kato S, Takeuchi K. Dual action of nitric oxide in pathogenesis of indomethacin-induced small intestinal ulceration in rats. <i>J. Physiol. Pharmacol.<\/i>, <b>50<\/b>, 405\u2013417 (1999)."},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW, Murphy WJ. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>90<\/b>, 9730\u20139734 (1993).","DOI":"10.1073\/pnas.90.20.9730"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. <i>J. Exp. Med.<\/i>, <b>177<\/b>, 1779\u20131784 (1993).","DOI":"10.1084\/jem.177.6.1779"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Heitmeier MR, Scarim AL, Corbett JA. Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. <i>J. Biol. Chem.<\/i>, <b>272<\/b>, 13697\u201313704 (1997).","DOI":"10.1074\/jbc.272.21.13697"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Heitmeier MR, Scarim AL, Corbett JA. Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. <i>J. Biol. Chem.<\/i>, <b>274<\/b>, 29266\u201329273 (1999).","DOI":"10.1074\/jbc.274.41.29266"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Chen CW, Chang YH, Tsi CJ, Lin WW. Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase\/STAT1 signaling pathway. <i>J. Immunol.<\/i>, <b>171<\/b>, 979\u2013988 (2003).","DOI":"10.4049\/jimmunol.171.2.979"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Burbach GJ, Naik SM, Harten JB, Liu L, Dithmar S, Grossniklaus H, Ward SL, Armstrong CA, Caughman SW, Ansel JC. Interleukin-18 expression and modulation in human corneal epithelial cells. <i>Curr. Eye Res.<\/i>, <b>23<\/b>, 64\u201368 (2001).","DOI":"10.1076\/ceyr.23.1.64.5425"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Sugawara S, Uehara A, Nochi T, Yamaguchi T, Ueda H, Sugiyama A, Hanzawa K, Kumagai K, Okamura H, Takada H. Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. <i>J. Immunol.<\/i>, <b>167<\/b>, 6568\u20136575 (2001).","DOI":"10.4049\/jimmunol.167.11.6568"}],"container-title":["Biological &amp; Pharmaceutical Bulletin","Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/38\/10\/38_b15-00375\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T00:19:31Z","timestamp":1567210771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/38\/10\/38_b15-00375\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b15-00375","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}