{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:33:55Z","timestamp":1780076035452,"version":"3.54.0"},"reference-count":31,"publisher":"Pharmaceutical Society of Japan","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2016]]},"DOI":"10.1248\/bpb.b16-00078","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T18:05:31Z","timestamp":1464717931000},"page":"1042-1046","source":"Crossref","is-referenced-by-count":33,"title":["Carbon Tetrachloride-Induced Nephrotoxicity in Mice Is Prevented by Pretreatment with Zinc Sulfate"],"prefix":"10.1248","volume":"39","author":[{"given":"Hiroki","family":"Yoshioka","sequence":"first","affiliation":[{"name":"College of Pharmacy, Kinjo Gakuin University"},{"name":"Faculty of Nutrition, Kobe Gakuin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruki","family":"Usuda","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Kinjo Gakuin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Fukuishi","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Kinjo Gakuin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsunemasa","family":"Nonogaki","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Kinjo Gakuin University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satomi","family":"Onosaka","sequence":"additional","affiliation":[{"name":"Faculty of Nutrition, Kobe Gakuin University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","unstructured":"1) McGregor D, Lang M. Carbon tetrachloride: genetic effects and other modes of action. <i>Mutat. Res.<\/i>, <b>366<\/b>, 181\u2013195 (1996)."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) El Denshary ES, Al-Gahazali MA, Mannaa FA, Salem HA, Hassan NS, Abdel-Wahhab MA. Dietary honey and ginseng protect against carbon tetrachloride-induced hepatonephrotoxicity in rats. <i>Exp. Toxicol. Pathol.<\/i>, <b>64<\/b>, 753\u2013760 (2012).","DOI":"10.1016\/j.etp.2011.01.012"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Fadhel ZA, Amran S. Effects of black tea extract on carbon tetrachloride-induced lipid peroxidation in liver, kidneys, and testes of rats. <i>Phytother. Res.<\/i>, <b>16<\/b> (Suppl. 1), S28\u2013S32 (2002).","DOI":"10.1002\/ptr.793"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Anand KV, Anandhi R, Pakkiyaraj M, Geraldine P. Protective effect of chrysin on carbon tetrachloride (CCl<sub>4<\/sub>)-induced tissue injury in male Wistar rats. <i>Toxicol. Ind. Health<\/i>, <b>27<\/b>, 923\u2013933 (2011).","DOI":"10.1177\/0748233711399324"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Abraham P, Wilfred G, Cathrine SP. Oxidative damage to the lipids and proteins pf the lungs, testis and kidney of rats during carbon tetrachloride intoxication. <i>Clin. Chim. Acta<\/i>, <b>289<\/b>, 177\u2013179 (1999).","DOI":"10.1016\/S0009-8981(99)00140-0"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Al-Sayed E, Abdel-Daim MM. Protective role of Cupressuflavone from <i>Cupressus macrocarpa<\/i> against carbon tetrachloride-induced hepato- and nephrotoxicity in mice. <i>Planta Med.<\/i>, <b>80<\/b>, 1665\u20131671 (2014).","DOI":"10.1055\/s-0034-1383211"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Hismiogullari AA, Hismiogullari SE, Karaca O, Sunay FB, Paksoy S, Can M, Kus I, Seyrek K, Yavuz O. The protective effect of curcumin administration on carbon tetrachloride (CCl<sub>4<\/sub>)-induced nephrotoxicity in rats. <i>Pharmacol. Rep.<\/i>, <b>67<\/b>, 410\u2013416 (2015).","DOI":"10.1016\/j.pharep.2014.10.021"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Hermenean A, Ardelean A, Stan M, Herman H, Mihali CV, Costache M, Dinischiotu A. Protective effects of naringenin on carbon tetrachloride-induced acute nephrotoxicity in mouse kidney. <i>Chem. Biol. Interact.<\/i>, <b>205<\/b>, 138\u2013147 (2013).","DOI":"10.1016\/j.cbi.2013.06.016"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Ebaid H, Al-Tamimi J, Hassan I, Alhazza I, Al-Khalifa M. Antioxidant bioactivity of Samsum ant (<i>Pachycondyla sennaarensis<\/i>) venom protects against CCL(4)-induced nephrotoxicity in mice. <i>Oxid. Med. Cell. Longev.<\/i>, <b>2014<\/b>, 763061 (2014).","DOI":"10.1155\/2014\/763061"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kataoka T, Nishiyama Y, Toyota T, Yoshimoto M, Sakoda A, Ishimori Y, Aoyama Y, Taguchi T, Yamaoka K. Radon inhalation protects mice from carbon\u2013tetrachloride-induced hepatic and renal damage. <i>Inflammation<\/i>, <b>34<\/b>, 559\u2013567 (2011).","DOI":"10.1007\/s10753-010-9263-7"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Hsouna AB, Saoudi M, Trigui M, Jamoussi K, Boudawara T, Jaoua S, Feki AE. Characterization of bioactive compounds and ameliorative effects of <i>Ceratonia siliqua<\/i> leaf extract against CCl(4) induced hepatic oxidative damage and renal failure in rats. <i>Food Chem. Toxicol.<\/i>, <b>49<\/b>, 3183\u20133191 (2011).","DOI":"10.1016\/j.fct.2011.09.034"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Sanzgiri UY, Srivatsan V, Muralidhara S, Dallas CE, Bruckner JV. Uptake, distribution, and elimination of carbon tetrachloride in rat tissues following inhalation and ingestion exposures. <i>Toxicol. Appl. Pharmacol.<\/i>, <b>143<\/b>, 120\u2013129 (1997).","DOI":"10.1006\/taap.1996.8079"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Weber LW, Boll M, Stampfl A. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. <i>Crit. Rev. Toxicol.<\/i>, <b>33<\/b>, 105\u2013136 (2003).","DOI":"10.1080\/713611034"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Powell SR. The antioxidant properties of zinc. <i>J. Nutr.<\/i>, <b>130<\/b> (Suppl.), 1447S\u20131454S (2000).","DOI":"10.1093\/jn\/130.5.1447S"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) McCall KA, Huang C, Fierke CA. Function and mechanism of zinc metalloenzymes. <i>J. Nutr.<\/i>, <b>130<\/b> (Suppl.), 1437S\u20131446S (2000).","DOI":"10.1093\/jn\/130.5.1437S"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Basu A, Lazo JS. A hypothesis regarding the protective role of metallothioneins against the toxicity of DNA interactive anticancer drugs. <i>Toxicol. Lett.<\/i>, <b>50<\/b>, 123\u2013135, discussion, 121\u2013122 (1990).","DOI":"10.1016\/0378-4274(90)90002-4"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Hamer DH. Metallothionein. <i>Annu. Rev. Biochem.<\/i>, <b>55<\/b>, 913\u2013951 (1986).","DOI":"10.1146\/annurev.bi.55.070186.004405"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Yoshioka H, Usuda H, Nonogaki T, Onosaka S. Carbon tetrachloride-induced lethality in mouse is prevented by multiple pretreatment with zinc sulfate. <i>J. Toxicol. Sci.<\/i>, <b>41<\/b>, 55\u201363 (2016).","DOI":"10.2131\/jts.41.55"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Onosaka S, Cherian MG. The induced synthesis of metallothionein in various tissues of rats in response to metals. II. Influence of zinc status and specific effect on pancreatic metallothionein. <i>Toxicology<\/i>, <b>23<\/b>, 11\u201320 (1982).","DOI":"10.1016\/0300-483X(82)90037-3"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Onosaka S, Tanaka K, Cherian MG. Effects of cadmium and zinc on tissue levels of metallothionein. <i>Environ. Health Perspect.<\/i>, <b>54<\/b>, 67\u201372 (1984).","DOI":"10.1289\/ehp.845467"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Wong FW, Chan WY, Lee SS. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression. <i>Toxicol. Appl. Pharmacol.<\/i>, <b>153<\/b>, 109\u2013118 (1998).","DOI":"10.1006\/taap.1998.8547"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Sapone A, Affatato A, Canistro D, Broccoli M, Trespidi S, Pozzetti L, Biagi GL, Cantelli-Forti G, Paolini M. Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice. <i>Mutat. Res.<\/i>, <b>527<\/b>, 67\u201380 (2003).","DOI":"10.1016\/S0027-5107(03)00055-1"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Starkey JM, Zhao Y, Sadygov RG, Haidacher SJ, Lejeune WS, Dey N, Luxon BA, Kane MA, Napoli JL, Denner L, Tilton RG. Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry. <i>PLoS ONE<\/i>, <b>5<\/b>, e11095 (2010).","DOI":"10.1371\/journal.pone.0011095"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Cagen SZ, Klaassen CD. Protection of carbon tetrachloride-induced hepatotoxicity by zinc: role of metallothionein. <i>Toxicol. Appl. Pharmacol.<\/i>, <b>51<\/b>, 107\u2013116 (1979).","DOI":"10.1016\/0041-008X(79)90013-9"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Thornalley PJ, Vasak M. Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. <i>Biochim. Biophys. Acta<\/i>, <b>827<\/b>, 36\u201344 (1985).","DOI":"10.1016\/0167-4838(85)90098-6"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Sato M, Bremner I. Oxygen free radicals and metallothionein. <i>Free Radic. Biol. Med.<\/i>, <b>14<\/b>, 325\u2013337 (1993).","DOI":"10.1016\/0891-5849(93)90029-T"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Sato M, Kondoh M. Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. <i>Tohoku J. Exp. Med.<\/i>, <b>196<\/b>, 9\u201322 (2002).","DOI":"10.1620\/tjem.196.9"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Khan MR, Rizvi W, Khan GN, Khan RA, Shaheen S. Carbon tetrachloride-induced nephrotoxicity in rats: protective role of <i>Digera muricata<\/i>. <i>J. Ethnopharmacol.<\/i>, <b>122<\/b>, 91\u201399 (2009).","DOI":"10.1016\/j.jep.2008.12.006"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Khan RA, Khan MR, Sahreen S, Bokhari J. Prevention of CCl<sub>4<\/sub>-induced nephrotoxicity with <i>Sonchus asper<\/i> in rat. <i>Food Chem. Toxicol.<\/i>, <b>48<\/b>, 2469\u20132476 (2010).","DOI":"10.1016\/j.fct.2010.06.016"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Sheweita SA, Abd El-Gabar M, Bastawy M. Carbon tetrachloride-induced changes in the activity of phase II drug-metabolizing enzyme in the liver of male rats: role of antioxidants. <i>Toxicology<\/i>, <b>165<\/b>, 217\u2013224 (2001).","DOI":"10.1016\/S0300-483X(01)00429-2"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Lushchak VI. Glutathione homeostasis and functions: potential targets for medical interventions. <i>J. Amino Acids<\/i>, <b>2012<\/b>, 736837 (2012).","DOI":"10.1155\/2012\/736837"}],"container-title":["Biological &amp; Pharmaceutical Bulletin","Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/39\/6\/39_b16-00078\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T22:48:57Z","timestamp":1567982937000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/39\/6\/39_b16-00078\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b16-00078","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}