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Origin of osteoclast: mature monocytes and macrophages are capable of differentiating into osteoclast under a suitable microenvironment prepared by bone marrow-derived stromal cells. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>87<\/b>, 7260\u20137264 (1990).","DOI":"10.1073\/pnas.87.18.7260"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. <i>Endocr. Rev.<\/i>, <b>21<\/b>, 115\u2013137 (2000).","DOI":"10.1210\/er.21.2.115"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Nason R, Jung JY, Chole RA. Lipopolysaccharide-induced osteoclastogenesis from mononuclear precursors: a mechanism for osteolysis in chronic otitis. <i>J. Assoc. Res. 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Purslane suppresses osteoclast differentiation and bone resorbing activity <i>via<\/i> inhibition of Akt\/GSK3\u03b2-c-Fos-NFATc1 signaling <i>in vitro<\/i> and prevents lipopolysaccharide-induced bone loss <i>in vivo<\/i>. <i>Biol. Pharm. Bull.<\/i>, <b>38<\/b>, 66\u201374 (2015).","DOI":"10.1248\/bpb.b14-00567"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Liu M, Liao K, Yu C, Li X, Liu S, Yang S. Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord. <i>Mediators Inflamm.<\/i>, <b>2014<\/b>, 485927 (2014).","DOI":"10.1155\/2014\/485927"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Yang X, Zhang H, Wang J, Zhang Z, Li C. Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis. <i>J. 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Puerarin concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-\u03baB ligand (RANKL) and interleukin-6 production in human osteoblastic MG-63 cells. <i>Phytomedicine<\/i>, <b>21<\/b>, 1032\u20131036 (2014).","DOI":"10.1016\/j.phymed.2014.04.012"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Wang PP, Zhu XF, Yang L, Liang H, Feng SW, Zhang RH. Puerarin stimulates osteoblasts differentiation and bone formation through estrogen receptor, p38 MAPK, and Wnt\/\u03b2-catenin pathways. <i>J. Asian Nat. Prod. Res.<\/i>, <b>14<\/b>, 897\u2013905 (2012).","DOI":"10.1080\/10286020.2012.702757"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Zhang Y, Zeng XH, Zhang L, Zheng XX. 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