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Lett.<\/i>, 223<\/b>, 5\u20138 (1997).","DOI":"10.1016\/S0304-3940(97)13391-2"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Shimoyama N, Shimoyama M, Elliott KJ, Inturrisi CE. d<\/i>-Methadone is antinociceptive in the rat formalin test. J. Pharmacol. Exp. Ther.<\/i>, 283<\/b>, 648\u2013652 (1997).","DOI":"10.1016\/S0022-3565(24)37037-5"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Ben\u00edtez-Rosario MA, Salinas Mart\u00edn A, G\u00f3mez-Onta\u00f1\u00f3n E, Feria M. Methadone-induced respiratory depression after discontinuing carbamazepine administration. J. Pain Symptom Manage.<\/i>, 32<\/b>, 99\u2013100 (2006).","DOI":"10.1016\/j.jpainsymman.2006.02.006"},{"key":"7","unstructured":"7) Tarumi Y, Pereira J, Watanabe S. Methadone and fluconazole: respiratory depression by drug interaction. J. Pain Symptom Manage.<\/i>, 23<\/b>, 148\u2013153 (2002)."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Hunt G, Bruera E. Respiratory depression in a patient receiving oral methadone for cancer pain. J. Pain Symptom Manage.<\/i>, 10<\/b>, 401\u2013404 (1995).","DOI":"10.1016\/0885-3924(95)00021-P"},{"key":"9","unstructured":"9) Modesto-Lowe V, Brooks D, Petry N. Methadone deaths: risk factors in pain and addicted populations. J. Gen. Intern. Med.<\/i>, 25<\/b>, 305\u2013309 (2010)."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Katchman AN, McGroary KA, Kilborn MJ, Kornick CA, Manfredi PL, Woosley RL, Ebert SN. Influence of opioid agonists on cardiac human ether-a-go-go-related gene K(+) currents. J. Pharmacol. Exp. Ther.<\/i>, 303<\/b>, 688\u2013694 (2002).","DOI":"10.1124\/jpet.102.038240"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Kornick CA, Kilborn MJ, Santiago-Palma J, Schulman G, Thaler HT, Keefe DL, Katchman AN, Pezzullo JC, Ebert SN, Woosley RL, Payne R, Manfredi PL. QTc interval prolongation associated with intravenous methadone. Pain<\/i>, 105<\/b>, 499\u2013506 (2003).","DOI":"10.1016\/S0304-3959(03)00205-7"},{"key":"12","unstructured":"12) Reddy S, Hui D, El Osta B, de la Cruz M, Walker P, Palmer JL, Bruera E. The effect of oral methadone on the QTc interval in advanced cancer patients: a prospective pilot study. J. Palliat. Med.<\/i>, 13<\/b>, 33\u201338 (2010)."},{"key":"13","unstructured":"13) Boglione-Kerrien C, Furet Y, Bachellier J, Paintaud G, Autret-Leca E. Methadone blood assay by the FPIA technique: application to the monitoring of patients in maintenance treatment to opiates. Ann. Biol. Clin.<\/i>, 65<\/b>, 51\u201357 (2007)."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Rook EJ, Hillebrand MJ, Rosing H, van Ree JM, Beijnen JH. The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry. J. 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