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Acarbose: safe and effective for lowering postprandial hyperglycaemia and improving cardiovascular outcomes. Open Heart<\/i>, 2<\/b>, e000327 (2015).","DOI":"10.1136\/openhrt-2015-000327"},{"key":"2","unstructured":"2) Lee MY, Choi DS, Lee MK, Lee HW, Park TS, Kim DM, Chung CH, Kim DK, Kim IJ, Jang HC, Park YS, Kwon HS, Lee SH, Shin HK. Comparison of acarbose and voglibose in diabetes patients who are inadequately controlled with basal insulin treatment: randomized, parallel, open-label, active-controlled study. J. Korean Med. Sci.<\/i>, 29<\/b>, 90\u201397 (2014)."},{"key":"3","unstructured":"3) Rosak C, Mertes G. Critical evaluation of the role of acarbose in the treatment of diabetes: patient considerations. Chinese Journal of Drug Evaluation<\/i>, 2012<\/b>, 357\u2013367 (2012)."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Dehghan-Kooshkghazi M, Mathers JC. Starch digestion, large-bowel fermentation and intestinal mucosal cell proliferation in rats treated with the alpha-glucosidase inhibitor acarbose. Br. J. Nutr.<\/i>, 91<\/b>, 357\u2013365 (2004).","DOI":"10.1079\/BJN20031063"},{"key":"5","unstructured":"5) Gross LS, Li L, Ford ES, Liu S. Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am. J. Clin. Nutr.<\/i>, 79<\/b>, 774\u2013779 (2004)."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Mart\u00ednez I, Kim J, Duffy PR, Schlegel VL, Walter J. Resistant starches types 2 and 4 have differential effects on the composition of the fecal microbiota in human subjects. PLoS ONE<\/i>, 5<\/b>, e15046 (2010).","DOI":"10.1371\/journal.pone.0015046"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Haenen D, Zhang J, Souza da Silva C, Bosch G, van der Meer IM, van Arkel J, van den Borne JJGC, Guti\u00e9rrez OP, Smidt H, Kemp B, M\u00fcller M, Hooiveld GJ. A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine. J. Nutr.<\/i>, 143<\/b>, 274\u2013283 (2013).","DOI":"10.3945\/jn.112.169672"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F, Liang S, Zhang W, Guan Y, Shen D, Peng Y, Zhang D, Jie Z, Wu W, Qin Y, Xue W, Li J, Han L, Lu D, Wu P, Dai Y, Sun X, Li Z, Tang A, Zhong S, Li X, Chen W, Xu R, Wang M, Feng Q, Gong M, Yu J, Zhang Y, Zhang M, Hansen T, Sanchez G, Raes J, Falony G, Okuda S, Almeida M, LeChatelier E, Renault P, Pons N, Batto JM, Zhang Z, Chen H, Yang R, Zheng W, Li S, Yang H, Wang J, Ehrlich SD, Nielsen R, Pedersen O, Kristiansen K, Wang J. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature<\/i>, 490<\/b>, 55\u201360 (2012).","DOI":"10.1038\/nature11450"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Zhang X, Shen D, Fang Z, Jie Z, Qiu X, Zhang C, Chen Y, Ji L. Human gut microbiota changes reveal the progression of glucose intolerance. PLOS ONE<\/i>, 8<\/b>, e71108 (2013).","DOI":"10.1371\/journal.pone.0071108"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM, Burcelin R. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes<\/i>, 57<\/b>, 1470\u20131481 (2008).","DOI":"10.2337\/db07-1403"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Shin NR, Lee JC, Lee HY, Kim MS, Whon TW, Lee MS, Bae JW. An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut<\/i>, 63<\/b>, 727\u2013735 (2014).","DOI":"10.1136\/gutjnl-2012-303839"},{"key":"12","unstructured":"12) Zhang X, Fang Z, Zhang C, Xia H, Jie Z, Han X, Chen Y, Ji L. Effects of acarbose on the gut microbiota of prediabetic patients: a randomized, double-blind, controlled crossover trial. Diabetes Therapy Research Treatment & Education of Diabetes & Related Disorders<\/i>, 8<\/b>, 293\u2013307 (2017)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Su B, Liu H, Li J, Sunli Y, Liu B, Liu D, Zhang P, Meng X. Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in Chinese patients with type 2 diabetes mellitus. J. Diabetes<\/i>, 7<\/b>, 729\u2013739 (2015).","DOI":"10.1111\/1753-0407.12232"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Blanch M, Calsamiglia S, Devant M, Bach A. Effects of acarbose on ruminal fermentation, blood metabolites and microbial profile involved in ruminal acidosis in lactating cows fed a high-carbohydrate ration. J. Dairy Res.<\/i>, 77<\/b>, 123\u2013128 (2010).","DOI":"10.1017\/S0022029909990562"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Yin YY, Liu YJ, Zhu WY, Mao SY. Effects of acarbose addition on ruminal bacterial microbiota, lipopolysaccharide levels and fermentation characteristics in vitro.<\/i> Asian-australas. J. Anim. Sci.<\/i>, 27<\/b>, 1726\u20131735 (2014).","DOI":"10.5713\/ajas.2014.14292"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes<\/i>, 58<\/b>, 1509\u20131517 (2009).","DOI":"10.2337\/db08-1637"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Donohoe DR, Garge N, Zhang X, Sun W, O\u2019Connell TM, Bunger MK, Bultman SJ. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab.<\/i>, 13<\/b>, 517\u2013526 (2011).","DOI":"10.1016\/j.cmet.2011.02.018"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Blouin JM, Penot G, Collinet M, Nacfer M, Forest C, Laurent-Puig P, Coumoul X, Barouki RCB, Benelli C, Bortoli S. Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex. International Journal of Cancer Journal International Du Cancer<\/i>, 128<\/b>, 2591\u20132601 (2011).","DOI":"10.1002\/ijc.25599"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Scharlau D, Borowicki A, Habermann N, Hofmann T, Klenow S, Miene C, Munjal U, Stein K, Glei M. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat. Res.<\/i>, 682<\/b>, 39\u201353 (2009).","DOI":"10.1016\/j.mrrev.2009.04.001"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Tang Y, Chen Y, Jiang H, Robbins GT, Nie D. G-Protein-coupled receptor for short-chain fatty acids suppresses colon cancer. International Journal of Cancer Journal International Du Cancer<\/i>, 128<\/b>, 847\u2013856 (2011).","DOI":"10.1002\/ijc.25638"},{"key":"21","unstructured":"21) Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ. Review article: the role of butyrate on colonic function. Aliment. Pharmacol. Ther.<\/i>, 27<\/b>, 104\u2013119 (2008)."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Weickert MO, Pfeiffer AF. Metabolic effects of dietary fiber consumption and prevention of diabetes. J. Nutr.<\/i>, 138<\/b>, 439\u2013442 (2008).","DOI":"10.1093\/jn\/138.3.439"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Cummings JH, Macfarlane GT. The control and consequences of bacterial fermentation in the human colon. J. Appl. Bacteriol.<\/i>, 70<\/b>, 443\u2013459 (1991).","DOI":"10.1111\/j.1365-2672.1991.tb02739.x"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Brewer RA, Gibbs VK, Smith DL Jr. Targeting glucose metabolism for healthy aging. Nutrition & Healthy Aging<\/i>, 4<\/b>, 31\u201346 (2016).","DOI":"10.3233\/NHA-160007"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Weaver GA, Tangel CT, Krause JA, Parfitt MM, Jenkins PL, Rader JM, Lewis BA, Miller TL, Wolin MJ. Acarbose enhances human colonic butyrate production. J. Nutr.<\/i>, 127<\/b>, 717\u2013723 (1997).","DOI":"10.1093\/jn\/127.5.717"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Hoek MJV, Merks RM. Redox balance is key to explaining full vs.<\/i> partial switching to low-yield metabolism. BMC Syst. Biol.<\/i>, 6<\/b>, 1\u201310 (2012).","DOI":"10.1186\/1752-0509-6-22"},{"key":"27","unstructured":"27) Meijer K, Vos PD, Priebe MG. Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health? Curr. Opin. Clin. Nutr. Metab. Care<\/i>, 13<\/b>, 715\u2013721 (2010)."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Sauer J, Richter KK, Pool-Zobel BL. Physiological concentrations of butyrate favorably modulate genes of oxidative and metabolic stress in primary human colon cells. J. Nutr. Biochem.<\/i>, 18<\/b>, 736\u2013745 (2007).","DOI":"10.1016\/j.jnutbio.2006.12.012"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Tang C, Offermanns S. FFA2 and FFA3 in metabolic regulation. Handbook Exp. Pharmacol.<\/i>, 236<\/b>, 205\u2013220 (2017).","DOI":"10.1007\/164_2016_50"},{"key":"30","unstructured":"30) Sleeth ML, Thompson EL, Ford HE, Zac-Varghese SE, Frost G. Free fatty acid receptor 2 and nutrient sensing: a proposed role for fibre, fermentable carbohydrates and short-chain fatty acids in appetite regulation. Nutr. Res. Rev.<\/i>, 23<\/b>, 135\u2013145 (2010)."},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Tang C, Ahmed K, Gille A, Lu S, Gr\u00f6ne HJ, Tunaru S, Offermanns S. Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes. Nat. Med.<\/i>, 21<\/b>, 173\u2013177 (2015).","DOI":"10.1038\/nm.3779"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Paiva L, Binsack R, Machado UF. Chronic acarbose-feeding increases GLUT1 protein without changing intestinal glucose absorption function. Eur. J. Pharmacol.<\/i>, 434<\/b>, 197\u2013204 (2002).","DOI":"10.1016\/S0014-2999(01)01538-2"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Ziegler K, Kerimi A, Poquet L, Williamson G. Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). Arch. Biochem. Biophys.<\/i>, 599<\/b>, 3\u201312 (2016).","DOI":"10.1016\/j.abb.2016.01.018"},{"key":"34","unstructured":"34) Hadjiagapiou C, Schmidt L, Dudeja PK, Layden TJ, Ramaswamy K. Mechanism(s) of butyrate transport in Caco-2 cells: role of monocarboxylate transporter 1. Am. J. Physiol. Gastrointest. Liver Physiol.<\/i>, 279<\/b>, G775\u2013G780 (2000)."},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Gon\u00e7alves P, Catarino T, Greg\u00f3rio I, Martel F. Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells. J. Cell. Biochem.<\/i>, 113<\/b>, 2937\u20132947 (2012).","DOI":"10.1002\/jcb.24172"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Tannock GW, Crichton C, Welling GW, Koopman JP, Midtvedt T. Reconstitution of the gastrointestinal microflora of lactobacillus-free mice. Appl. Environ. Microbiol.<\/i>, 54<\/b>, 2971\u20132975 (1988).","DOI":"10.1128\/AEM.54.12.2971-2975.1988"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Pe\u00f1a AG, Goodrich JK, Gordon JI, Huttley GA, Kelley ST, Knights D, Koenig JE, Ley RE, Lozupone CA, McDonald D, Muegge BD, Pirrung M, Reeder J, Sevinsky JR, Turnbaugh PJ, Walters WA, Widmann J, Yatsunenko T, Zaneveld J, Knight R. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods<\/i>, 7<\/b>, 335\u2013336 (2010).","DOI":"10.1038\/nmeth.f.303"},{"key":"38","unstructured":"38) Parks DH, Tyson GW, Hugenholtz P, Beiko RG. STAMP: statistical analysis of taxonomic and functional profiles. Bioinformatics<\/i>, 30<\/b>, 3123\u20133124 (2014)."},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) Jiminez JA, Uwiera TC, Abbott DW, Uwiera RRE, Inglis GD. Impacts of resistant starch and wheat bran consumption on enteric inflammation in relation to colonic bacterial community structures and short-chain fatty acid concentrations in mice. Gut Pathogens<\/i>, 8<\/b>, 67 (2016).","DOI":"10.1186\/s13099-016-0149-6"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Besten GD, Havinga R, Bleeker A, Rao S, Gerding A, Eunen KV, Groen AK, Reijngoud DJ, Bakker BM. The short-chain fatty acid uptake fluxes by mice on a guar gum supplemented diet associate with amelioration of major biomarkers of the metabolic syndrome. PLOS ONE<\/i>, 9<\/b>, e107392 (2014).","DOI":"10.1371\/journal.pone.0107392"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41) Tian L, Bruggeman G, Van DBM, Borewicz K, Scheurink AJ, Bruininx E, De VP, Smidt H, Schols HA, Gruppen H. Effects of pectin on fermentation characteristics, carbohydrate utilization, and microbial community composition in the gastrointestinal tract of weaning pigs. Mol. Nutr. Food Res.<\/i>, 61<\/b>, 201600186 (2017).","DOI":"10.1002\/mnfr.201600186"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42) Weitkunat K, Schumann S, Petzke KJ, Blaut M, Loh G, Klaus S. Effects of dietary inulin on bacterial growth, short-chain fatty acid production and hepatic lipid metabolism in gnotobiotic mice. J. Nutr. Biochem.<\/i>, 26<\/b>, 929\u2013937 (2015).","DOI":"10.1016\/j.jnutbio.2015.03.010"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43) Derosa G, Maffioli P. \u03b1-Glucosidase inhibitors and their use in clinical practice. Archives of Medical Science Ams<\/i>, 5<\/b>, 899\u2013906 (2012).","DOI":"10.5114\/aoms.2012.31621"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44) Morgan S, Mackay A. Summary of Product Characteristics<\/i>. Springer, Berlin, Heidelberg (2010).","DOI":"10.1007\/978-3-540-68706-1_698"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45) Holt PR, Atillasoy E, Lindenbaum J, Ho SB, Lupton JR, Mcmahon D, Moss SF. Effects of acarbose on fecal nutrients, colonic pH, and short-chain fatty acids and rectal proliferative indices. Metabolism<\/i>, 45<\/b>, 1179\u20131187 (1996).","DOI":"10.1016\/S0026-0495(96)90020-7"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46) Tazoe H, Otomo Y, Karaki S, Kato I, Fukami Y, Terasaki M, Kuwahara A. Expression of short-chain fatty acid receptor GPR41 in the human colon. Biomed. Res.<\/i>, 30<\/b>, 149\u2013156 (2009).","DOI":"10.2220\/biomedres.30.149"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Itagaki S, Gopal E, Zhuang L, Fei YJ, Miyauchi S, Prasad PD, Ganapathy V. Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8). Pharm. Res.<\/i>, 23<\/b>, 1209\u20131216 (2006).","DOI":"10.1007\/s11095-006-0023-1"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) Knudsen KEB. Microbial Degradation of whole-grain complex carbohydrates and impact on short-chain fatty acids and health. Advances in Nutrition<\/i>, 6<\/b>, 206\u2013213 (2015).","DOI":"10.3945\/an.114.007450"},{"key":"49","unstructured":"49) Knudsen KEB. Effect of dietary non-digestible carbohydrates on the rate of SCFA delivery to peripheral tissues (feature articles: International Symposium on Non-digestible Carbohydrate (2)). Foods & Food Ingredients Journal of Japan<\/i>, 210<\/b>, 1008\u20131017 (2005)."},{"key":"50","doi-asserted-by":"crossref","unstructured":"50) Ceelen L, De Spiegelaere W, David M, De Craene J, Vinken M, Vanhaecke T, Rogiers V. Critical selection of reliable reference genes for gene expression study in the HepaRG cell line. Biochem. Pharmacol.<\/i>, 81<\/b>, 1255\u20131261 (2011).","DOI":"10.1016\/j.bcp.2011.03.004"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Li WL, Chen ML, Liu SS, Li GL, Gu TY, Liang P, Qin YM, Zhan YH, Quan Y, Zhang GH. Sweet preference modified by early experience in mice and the related molecular modulations on the peripheral pathway. J. Mol. Neurosci.<\/i>, 51<\/b>, 225\u2013236 (2013).","DOI":"10.1007\/s12031-013-0011-y"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52) Meijer TW, Bussink J, Zatovicova M, Span PN, Lok J, Supuran CT, Kaanders JH. Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model. PLOS ONE<\/i>, 9<\/b>, e108068 (2014).","DOI":"10.1371\/journal.pone.0108068"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53) Singh V, Grotzinger C, Nowak KW, Zacharias S, Goncz E, Pless G, Sauer IM, Eichhorn I, Pfeiffer-Guglielmi B, Hamprecht B, Wiedenmann B, Plockinger U, Strowski MZ. Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition. Endocrinology<\/i>, 148<\/b>, 3887\u20133899 (2007).","DOI":"10.1210\/en.2006-1659"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54) Wang CW, Chang WL, Huang YC, Chou FC, Chan FN, Su SC, Huang SF, Ko HH, Ko YL, Lin HC, Chang TC. An essential role of cAMP response element-binding protein in epidermal growth factor-mediated induction of sodium\/glucose cotransporter 1 gene expression and intestinal glucose uptake. Int. J. Biochem. 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