{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:46:40Z","timestamp":1765828000048},"reference-count":8,"publisher":"Pharmaceutical Society of Japan","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2021,4,1]]},"DOI":"10.1248\/bpb.b19-01072","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T22:07:10Z","timestamp":1611612430000},"page":"585-589","source":"Crossref","is-referenced-by-count":6,"title":["Characterization of an Expanded IL-10-Producing-Suppressive T Cell Population Associated with Immune Tolerance"],"prefix":"10.1248","volume":"44","author":[{"given":"Yuya","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihisa","family":"Mikami","sequence":"additional","affiliation":[{"name":"Department of Experimental Immunology, Immunology Frontier Research Center, Osaka University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Saimoto","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arata","family":"Nagaike","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruka","family":"Shimono","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeyuki","family":"Kohno","sequence":"additional","affiliation":[{"name":"Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Yoshida Y, Tsuji T, Watanabe S, Matsushima A, Matsushima Y, Banno R, Fujita T, Kohno T. Efficacy of combination treatment with fingolimod (FTY720) plus pathogenic autoantigen in a glucose-6-phosphate isomerase peptide (GPI<sub>325\u2013339<\/sub>)-induced arthritis mouse model. <i>Biol. Pharm. Bull.<\/i>, <b>36<\/b>, 1739\u20131746 (2013).","DOI":"10.1248\/bpb.b13-00297"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Yoshida Y, Mikami N, Matsushima Y, Otani F, Miyawaki M, Takatsuji M, Banno R, Tsuji T, Fujita T, Tsujikawa K, Kohno T. Functional mechanism(s) of the inhibition of disease progression by combination treatment with fingolimod plus pathogenic antigen in a glucose-6-phosphate isomerase peptide-induced arthritis mouse model. <i>Biol. Pharm. Bull.<\/i>, <b>38<\/b>, 1120\u20131125 (2015).","DOI":"10.1248\/bpb.b14-00873"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Yoshida Y, Mikami N, Matsushima Y, Miyawaki M, Endo H, Banno R, Tsuji T, Fujita T, Kohno T. Combination treatment with fingolimod and a pathogenic antigen prevents relapse of glucose-6-phosphate isomerase peptide-induced arthritis. <i>Immun. Inflamm. Dis.<\/i>, <b>4<\/b>, 263\u2013273 (2016).","DOI":"10.1002\/iid3.111"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Iwanami K, Matsumoto I, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T. Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis. <i>Arthritis Res. Ther.<\/i>, <b>10<\/b>, R130 (2008).","DOI":"10.1186\/ar2545"},{"key":"5","unstructured":"5) Yoshida Y, Kohno T. Induction of immune tolerance by using fingolimod (FTY720), an immunosuppressive drug. <i>Clinical Immunology &amp; Allergology<\/i>, <b>71<\/b>, 508\u2013514 (2019)."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Lozano E, Dominguez-Villar M, Kuchroo V, Hafler DA. The TIGIT\/CD226 axis regulates human T cell function. <i>J. Immunol.<\/i>, <b>188<\/b>, 3869\u20133875 (2012).","DOI":"10.4049\/jimmunol.1103627"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Mascanfroni ID, Takenaka MC, Yeste A, Patel B, Wu Y, Kenison JE, Siddiqui S, Basso AS, Otterbein LE, Pardoll DM, Pan F, Priel A, Clish CB, Robson SC, Quintana FJ. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-\u03b1. <i>Nat. Med.<\/i>, <b>21<\/b>, 638\u2013646 (2015).","DOI":"10.1038\/nm.3868"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, Ernst M, Saris CJ, O\u2019Shea JJ, Hunter CA. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. <i>Nat. Immunol.<\/i>, <b>8<\/b>, 1363\u20131371 (2007).","DOI":"10.1038\/ni1537"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/44\/4\/44_b19-01072\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,3]],"date-time":"2021-04-03T03:28:20Z","timestamp":1617420500000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/44\/4\/44_b19-01072\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,1]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b19-01072","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,1]]}}}