{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:44:39Z","timestamp":1783705479224,"version":"3.55.0"},"reference-count":17,"publisher":"Pharmaceutical Society of Japan","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2020,8,1]]},"DOI":"10.1248\/bpb.b20-00101","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T22:07:43Z","timestamp":1596233263000},"page":"1202-1209","source":"Crossref","is-referenced-by-count":9,"title":["10-Hydroxydecanoic Acid Potentially Elicits Antigen-Specific IgA Responses"],"prefix":"10.1248","volume":"43","author":[{"given":"Tatsuya","family":"Isayama","sequence":"first","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikaru","family":"Etoh","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kishimoto","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshimasa","family":"Takasaki","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumi","family":"Kuratani","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Ikuta","sequence":"additional","affiliation":[{"name":"Institute for Bee Products and Health Science, Yamada Bee Company, Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Tatefuji","sequence":"additional","affiliation":[{"name":"Institute for Bee Products and Health Science, Yamada Bee Company, Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutoki","family":"Takamune","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsunobu","family":"Muneoka","sequence":"additional","affiliation":[{"name":"Shin Nippon Biomedical Laboratories, Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Shin Nippon Biomedical Laboratories, Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shogo","family":"Misumi","sequence":"additional","affiliation":[{"name":"Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Isidorov VA, Bakier S, Grzech I. Gas chromatographic-mass spectrometric investigation of volatile and extractable compounds of crude royal jelly. <i>J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.<\/i>, <b>885-886<\/b>, 109\u2013116 (2012).","DOI":"10.1016\/j.jchromb.2011.12.025"},{"key":"2","unstructured":"2) Townsend GF, Morgan JF, Tolnai S, Hazlett B, Morton HJ, Shuel RW. Studies on the <i>in vitro<\/i> antitumor activity of fatty acids. I. 10-Hydroxy-2-decenoic acid from royal jelly. <i>Cancer Res.<\/i>, <b>20<\/b>, 503\u2013510 (1960)."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Blum MS, Novak AF, Taber S 3rd. 10-Hydroxy-delta 2-decenoic acid, an antibiotic found in royal jelly. <i>Science<\/i>, <b>130<\/b>, 452\u2013453 (1959).","DOI":"10.1126\/science.130.3373.452"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Chen YF, Wang K, Zhang YZ, Zheng YF, Hu FL. <i>In vitro<\/i> anti-inflammatory effects of three fatty acids from Royal Jelly. <i>Mediators Inflamm.<\/i>, <b>2016<\/b>, 3583684 (2016).","DOI":"10.1155\/2016\/3583684"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Kai H, Motomura Y, Saito S, Hashimoto K, Tatefuji T, Takamune N, Misumi S. Royal jelly enhances antigen-specific mucosal IgA response. <i>Food Sci. Nutr.<\/i>, <b>1<\/b>, 222\u2013227 (2013).","DOI":"10.1002\/fsn3.29"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Snippert HJ, van der Flier LG, Sato T, van Es JH, van den Born M, Kroon-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. <i>Cell<\/i>, <b>143<\/b>, 134\u2013144 (2010).","DOI":"10.1016\/j.cell.2010.09.016"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Knoop KA, Kumar N, Butler BR, Sakthivel SK, Taylor RT, Nochi T, Akiba H, Yagita H, Kiyono H, Williams IR. RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium. <i>J. Immunol.<\/i>, <b>183<\/b>, 5738\u20135747 (2009).","DOI":"10.4049\/jimmunol.0901563"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Nagashima K, Sawa S, Nitta T, Tsutsumi M, Okamura T, Penninger JM, Nakashima T, Takayanagi H. Identification of subepithelial mesenchymal cells that induce IgA and diversify gut microbiota. <i>Nat. Immunol.<\/i>, <b>18<\/b>, 675\u2013682 (2017).","DOI":"10.1038\/ni.3732"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Kanaya T, Sakakibara S, Jinnohara T, Hachisuka M, Tachibana N, Hidano S, Kobayashi T, Kimura S, Iwanaga T, Nakagawa T, Katsuno T, Kato N, Akiyama T, Sato T, Williams IR, Ohno H. Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-\u03baB signaling. <i>J. Exp. Med.<\/i>, <b>215<\/b>, 501\u2013519 (2018).","DOI":"10.1084\/jem.20160659"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kern\u00e9is S, Bogdanova A, Kraehenbuhl JP, Pringault E. Conversion by Peyer\u2019s patch lymphocytes of human enterocytes into M cells that transport bacteria. <i>Science<\/i>, <b>277<\/b>, 949\u2013952 (1997).","DOI":"10.1126\/science.277.5328.949"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Cook DN, Prosser DM, Forster R, Zhang J, Kuklin NA, Abbondanzo SJ, Niu XD, Chen SC, Manfra DJ, Wiekowski MT, Sullivan LM, Smith SR, Greenberg HB, Narula SK, Lipp M, Lira SA. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. <i>Immunity<\/i>, <b>12<\/b>, 495\u2013503 (2000).","DOI":"10.1016\/S1074-7613(00)80201-0"},{"key":"12","unstructured":"12) Westphal S, L\u00fcgering A, von Wedel J, von Eiff C, Maaser C, Spahn T, Heusipp G, Schmidt MA, Herbst H, Williams IR, Domschke W, Kucharzik T. Resistance of chemokine receptor 6-deficient mice to Yersinia enterocolitica infection: evidence of defective M-cell formation <i>in vivo.<\/i> <i>Am. J. Pathol.<\/i>, <b>172<\/b>, 671\u2013680 (2008)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Ebisawa M, Hase K, Takahashi D, Kitamura H, Knoop KA, Williams IR, Ohno H. CCR6hiCD11c (int) B cells promote M-cell differentiation in Peyer\u2019s patch. <i>Int. Immunol.<\/i>, <b>23<\/b>, 261\u2013269 (2011).","DOI":"10.1093\/intimm\/dxq478"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Kobayashi A, Donaldson DS, Erridge C, Kanaya T, Williams IR, Ohno H, Mahajan A, Mabbott NA. The functional maturation of M cells is dramatically reduced in the Peyer\u2019s patches of aged mice. <i>Mucosal Immunol.<\/i>, <b>6<\/b>, 1027\u20131037 (2013).","DOI":"10.1038\/mi.2012.141"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Terahara K, Yoshida M, Igarashi O, Nochi T, Pontes GS, Hase K, Ohno H, Kurokawa S, Mejima M, Takayama N, Yuki Y, Lowe AW, Kiyono H. Comprehensive gene expression profiling of Peyer\u2019s patch M cells, villous M-like cells, and intestinal epithelial cells. <i>J. Immunol.<\/i>, <b>180<\/b>, 7840\u20137846 (2008).","DOI":"10.4049\/jimmunol.180.12.7840"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Kobayashi A, Donaldson DS, Kanaya T, Fukuda S, Baillie JK, Freeman TC, Ohno H, Williams IR, Mabbott NA. Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations. <i>DNA Res.<\/i>, <b>19<\/b>, 407\u2013422 (2012).","DOI":"10.1093\/dnares\/dss022"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) de Lau W, Kujala P, Schneeberger K, Middendorp S, Li VS, Barker N, Martens A, Hofhuis F, DeKoter RP, Peters PJ, Nieuwenhuis E, Clevers H. Peyer\u2019s patch M cells derived from Lgr5 (+) stem cells require SpiB and are induced by RankL in cultured \u201cminiguts.\u201d <i>Mol. Cell. Biol.<\/i>, <b>32<\/b>, 3639\u20133647 (2012).","DOI":"10.1128\/MCB.00434-12"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/43\/8\/43_b20-00101\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T03:19:28Z","timestamp":1596251968000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/43\/8\/43_b20-00101\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b20-00101","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,1]]}}}