{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T02:08:43Z","timestamp":1781748523987,"version":"3.54.5"},"reference-count":33,"publisher":"Pharmaceutical Society of Japan","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological &amp; Pharmaceutical Bulletin","Biol. Pharm. Bull."],"published-print":{"date-parts":[[2023,7,1]]},"DOI":"10.1248\/bpb.b23-00098","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T22:13:25Z","timestamp":1683929605000},"page":"946-954","source":"Crossref","is-referenced-by-count":2,"title":["Dimethylglycine, a Methionine Metabolite, Participates in the Suppressive Effect of Methionine on 1-Fluoro-2,4-dinitrobenzene-Induced Dermatitis"],"prefix":"10.1248","volume":"46","author":[{"given":"Takayuki","family":"Koga","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kie","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuka","family":"Hirayama","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Hiromura","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonaga","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Ishii","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayo","family":"Hirao-Suzuki","sequence":"additional","affiliation":[{"name":"Laboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuso","family":"Takeda","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Life Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Toda","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumio","family":"Soeda","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Daiichi University of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Becker D. Allergic contact dermatitis. <i>JDDG J. Dtsch. Dermatol. Ges.<\/i>, <b>11<\/b>, 607\u2013621 (2013).","DOI":"10.1111\/ddg.12143"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Brites GS, Ferreira I, Sebasti\u00e3o AI, Silva A, Carrascal M, Neves BM, Cruz MT. Allergic contact dermatitis: from pathophysiology to development of new preventive strategies. <i>Pharmacol. Res.<\/i>, <b>162<\/b>, 105282 (2020).","DOI":"10.1016\/j.phrs.2020.105282"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Lambert J. Itch in allergic contact dermatitis. <i>Front. Allergy<\/i>, <b>2<\/b>, 702488 (2021).","DOI":"10.3389\/falgy.2021.702488"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Alipour Tehrany Y, Coulombe J. Mango allergic contact dermatitis. <i>Contact Dermatitis<\/i>, <b>85<\/b>, 241\u2013242 (2021).","DOI":"10.1111\/cod.13818"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Atwater AR, Ward JM, Liu B, Green CL, Belsito DV, Sasseville D, Dekoven JG, Reeder MJ, Taylor JS, Maibach HI, Silverberg JI, Zug KA, Fowler JF Jr, Pratt MD, Deleo VA, Warshaw EM. Fragrance- and botanical-related allergy and associated concomitant reactions: a retrospective analysis of the North American contact dermatitis group data 2007\u20132016. <i>Dermatitis<\/i>, <b>32<\/b>, 42\u201352 (2021).","DOI":"10.1097\/DER.0000000000000661"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Felmingham C, Nixon R, Palmer A, Lee A. Allergic contact dermatitis caused by benzisothiazolinone in a continuous positive airway pressure mask liquid soap. <i>Contact Dermatitis<\/i>, <b>81<\/b>, 152\u2013153 (2019).","DOI":"10.1111\/cod.13273"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Kostner L, Anzengruber F, Guillod C, Recher M, Schmid-Grendelmeier P, Navarini AA. Allergic contact dermatitis. <i>Immunol. Allergy Clin. North Am.<\/i>, <b>37<\/b>, 141\u2013152 (2017).","DOI":"10.1016\/j.iac.2016.08.014"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Johansen JD, Bonefeld CM, Schwensen JFB, Thyssen JP, Uter W. Novel insights into contact dermatitis. <i>J. Allergy Clin. Immunol.<\/i>, <b>149<\/b>, 1162\u20131171 (2022).","DOI":"10.1016\/j.jaci.2022.02.002"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Adisesh A, Robinson E, Nicholson PJ, Sen D, Wilkinson M. U.K. standards of care for occupational contact dermatitis and occupational contact urticaria. <i>Br. J. Dermatol.<\/i>, <b>168<\/b>, 1167\u20131175 (2013).","DOI":"10.1111\/bjd.12256"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Katoh N, Ohya Y, Ikeda M, Ebihara T, Katayama I, Saeki H, Shimojo N, Tanaka A, Nakahara T, Nagao M, Hide M, Fujita Y, Fujisawa T, Futamura M, Masuda K, Murota H, Yamamoto-Hanada K. Japanese guidelines for atopic dermatitis 2020. <i>Allergol. Int.<\/i>, <b>69<\/b>, 356\u2013369 (2020).","DOI":"10.1016\/j.alit.2020.02.006"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Tanei R. Atopic dermatitis in older adults: a review of treatment options. <i>Drugs Aging<\/i>, <b>37<\/b>, 149\u2013160 (2020).","DOI":"10.1007\/s40266-020-00750-5"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Miller JD. The role of dust mites in allergy. <i>Clin. Rev. Allergy Immunol.<\/i>, <b>57<\/b>, 312\u2013329 (2019).","DOI":"10.1007\/s12016-018-8693-0"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Tupker RA, De Monchy JGR, Coenraads PJ. House-dust mite hypersensitivity, eczema, and other nonpulmonary manifestations of allergy. <i>Allergy<\/i>, <b>53<\/b> (Suppl.), 92\u201396 (1998).","DOI":"10.1111\/j.1398-9995.1998.tb05006.x"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Koga T, Hirayama F, Satoh T, Ishii Y, Kashige N, Hiromura M, Soeda F, Toda A. Methionine is a key regulator in the onset of atopic dermatitis in NC\/Nga mice. <i>BPB Reports<\/i>, <b>4<\/b>, 47\u201354 (2021).","DOI":"10.1248\/bpbreports.4.1_47"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Novak N. New insights into the mechanism and management of allergic diseases: atopic dermatitis. <i>Allergy<\/i>, <b>64<\/b>, 265\u2013275 (2009).","DOI":"10.1111\/j.1398-9995.2008.01922.x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Cabanillas B, Brehler AC, Novak N. Atopic dermatitis phenotypes and the need for personalized medicine. <i>Curr. Opin. Allergy Clin. Immunol.<\/i>, <b>17<\/b>, 309\u2013315 (2017).","DOI":"10.1097\/ACI.0000000000000376"},{"key":"17","unstructured":"17) Malorny U, Knop J, Burmeister G, Sorg C. Immunohistochemical demonstration of migration inhibitory factor (MIF) in experimental allergic contact dermatitis. <i>Clin. Exp. Immunol.<\/i>, <b>71<\/b>, 164\u2013170 (1988)."},{"key":"18","unstructured":"18) Nagai H, Ueda Y, Tanaka H, Hirano Y, Nakamura N, Inagaki N, Takatsu K, Kawada K. Effect of overproduction of interleukin 5 on dinitrofluorobenzene-induced allergic cutaneous response in mice. <i>J. Pharmacol. Exp. Ther.<\/i>, <b>288<\/b>, 43\u201350 (1999)."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Kinsell LW, Harper HA, Giese GK, Margen S, McCallie DP, Hess JR. Studies in methionine metabolism. II. Fasting plasma methionine levels in normal and hepatopathic individuals in response to daily methionine ingestion. <i>J. Clin. Invest.<\/i>, <b>28<\/b>, 1439\u20131450 (1949).","DOI":"10.1172\/JCI102209"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Kinsell LW, Margen S, Tarver H, Frantz JM, Flanagan EK, Hutchin ME, Michaels GD, McCallie DP. Studies in methionine metabolism. III. The fate of intravenously administered S35-labeled-methionine in normal adult males, in patients with chronic hepatic disease, \u201cidiopathic\u201d hypoproteinemia and Cushing\u2019s syndrome. <i>J. Clin. Invest.<\/i>, <b>29<\/b>, 238\u2013250 (1950).","DOI":"10.1172\/JCI102251"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Ikeda S, Koyama H, Sugimoto M, Kume S. Roles of one-carbon metabolism in preimplantation period\u2014effects on short-term development and long-term programming. <i>J. Reprod. Dev.<\/i>, <b>58<\/b>, 38\u201343 (2012).","DOI":"10.1262\/jrd.2011-002"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Durand P, Prost M, Loreau N, Lussier-Cacan S, Blache D. Impaired homocysteine metabolism and atherothrombotic disease. <i>Lab. Invest.<\/i>, <b>81<\/b>, 645\u2013672 (2001).","DOI":"10.1038\/labinvest.3780275"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Wycz\u00f3\u0142kowska J, Brzezi\u0144ska-B\u0142aszczyk E, Ma\u015bli\u0144ski C. Kinetics of specific IgE antibody and total IgE responses in mice: the effect of immunosuppressive treatment. <i>Int. Arch. Allergy Appl. Immunol.<\/i>, <b>72<\/b>, 16\u201321 (1983).","DOI":"10.1159\/000234834"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Brzezi\u0144ska-B\u0142aszczyk E, Zawilska J, Wycz\u00f3\u0142kowska J. Histamine-releasing properties of mast cells from various strains of mice. <i>Agents Actions<\/i>, <b>14<\/b>, 361\u2013364 (1984).","DOI":"10.1007\/BF01973828"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Bonneville M, Chavagnac C, Vocanson M, Rozieres A, Benetiere J, Pernet I, Denis A, Nicolas JF, Hennino A. Skin contact irritation conditions the development and severity of allergic contact dermatitis. <i>J. Invest. Dermatol.<\/i>, <b>127<\/b>, 1430\u20131435 (2007).","DOI":"10.1038\/sj.jid.5700726"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Arakawa T, Sugiyama T, Matsuura H, Okuno T, Ogino H, Sakazaki F, Ueno H. Effects of supplementary seleno-L-methionine on atopic dermatitis-like skin lesions in mice. <i>Biol. Pharm. Bull.<\/i>, <b>41<\/b>, 1456\u20131462 (2018).","DOI":"10.1248\/bpb.b18-00349"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Arakawa T, Okubo H, Mae M, Okuno T, Ogino H, Ueno H. Seleno-L-methionine suppresses immunoglobulin E-mediated allergic response in RBL-2H3 cells. <i>Biol. Pharm. Bull.<\/i>, <b>42<\/b>, 1179\u20131184 (2019).","DOI":"10.1248\/bpb.b19-00098"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Hiramoto K, Goto K, Tanaka S, Horikawa T, Ooi K. Skin, liver, and kidney interactions contribute to skin dryness in aging KK-Ay\/Tajcl mice. <i>Biomedicines<\/i>, <b>10<\/b>, 2648 (2022).","DOI":"10.3390\/biomedicines10102648"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Keczkes K, Lyell A. Intractable pruritus due to hepatic cirrhosis relieved by cholestyramine. <i>Postgrad. Med. J.<\/i>, <b>41<\/b>, 155\u2013157 (1965).","DOI":"10.1136\/pgmj.41.473.155"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Kam PCA, Tan KH. Pruritus\u2014itching for a cause and relief? <i>Anaesthesia<\/i>, <b>51<\/b>, 1133\u20131138 (1996).","DOI":"10.1111\/j.1365-2044.1996.tb15050.x"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Seino S, Tanaka Y, Honma T, Yanaka M, Sato K, Shinohara N, Ito J, Tsuduki T, Nakagawa K, Miyazawa T, Ikeda I. Atopic dermatitis causes lipid accumulation in the liver of NC\/Nga mouse. <i>J. Clin. Biochem. Nutr.<\/i>, <b>50<\/b>, 152\u2013157 (2012).","DOI":"10.3164\/jcbn.11-29"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Kimata H. Fatty liver in atopic dermatitis. <i>Allergy<\/i>, <b>56<\/b>, 460 (2001).","DOI":"10.1034\/j.1398-9995.2001.056005460.x"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Ogdie A, Grewal SK, Noe MH, Shin DB, Takeshita J, Chiesa Fuxench ZC, Carr RM, Gelfand JM. Risk of incident liver disease in patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis: a population-based study. <i>J. Invest. Dermatol.<\/i>, <b>138<\/b>, 760\u2013767 (2018).","DOI":"10.1016\/j.jid.2017.10.024"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/46\/7\/46_b23-00098\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T03:24:25Z","timestamp":1688181865000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/46\/7\/46_b23-00098\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,1]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b23-00098","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,1]]},"article-number":"b23-00098"}}