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pregnancy.\u201d: &lt;https:\/\/www.unfpa.org\/sites\/default\/files\/pub-pdf\/EN_SWP22%20report_0.pdf&gt;, accessed 14 July, 2025."},{"key":"2","unstructured":"2) World Health Organization. 2022. \u201cAbortion care guideline. World Health Organization.\u201d: &lt;https:\/\/www.who.int\/publications\/i\/item\/9789240039483&gt;, accessed 14 July, 2025."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Bearak J, Popinchalk A, Ganatra B, Moller AB, Tun\u00e7alp \u00d6, Beavin C, Kwok L, Alkema L. Unintended pregnancy and abortion by income, region, and the legal status of abortion: estimates from a comprehensive model for 1990-2019. <i>Lancet Glob. Health<\/i>, <b>8<\/b>, e1152\u2013e1161 (2020).","DOI":"10.1016\/S2214-109X(20)30315-6"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Sedgh G, Bearak J, Singh S, Bankole A, Popinchalk A, Ganatra B, Rossier C, Gerdts C, Tun\u00e7alp \u00d6., Johnson BR Jr, Johnston HB, Alkema L. Abortion incidence between 1990 and 2014: global, regional, and subregional levels and trends. <i>Lancet<\/i>, <b>388<\/b>, 258\u2013267 (2016).","DOI":"10.1016\/S0140-6736(16)30380-4"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Ganatra B, Gerdts C, Rossier C, Johnson BR Jr, Tun\u00e7alp \u00d6, Assifi A, Sedgh G, Singh S, Bankole A, Popinchalk A, Bearak J, Kang Z, Alkema L. Global, regional, and subregional classification of abortions by safety, 2010\u201314: estimates from a Bayesian hierarchical model. <i>Lancet<\/i>, <b>390<\/b>, 2372\u20132381 (2017).","DOI":"10.1016\/S0140-6736(17)31794-4"},{"key":"6","unstructured":"6) Ministry of Health. Labour and Welfare, 2023. \u201cReport on public health administration and services.\u201d: &lt;https:\/\/www.mhlw.go.jp\/toukei\/saikin\/hw\/eisei_houkoku\/23\/dl\/gaikyo.pdf&gt;, accessed 14 July, 2025."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Okui T. Association of socioeconomic status with unintended pregnancy and induced abortion in married couples: an analysis of the 2021 national survey data in Japan. <i>Clin. Epidemiol. Glob. Health<\/i>, <b>30<\/b>, 101814 (2024).","DOI":"10.1016\/j.cegh.2024.101814"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Bridwell RE, Long B, Montrief T, Gottlieb M. Post-abortion complications: a narrative review for emergency clinicians. <i>West. J. Emerg. Med.<\/i>, <b>23<\/b>, 919\u2013925 (2022).","DOI":"10.5811\/westjem.2022.8.57929"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Major B, Cozzarelli C, Cooper ML, Zubek J, Richards C, Wilhite M, Gramzow RH. Psychological responses of women after first-trimester abortion. <i>Arch. Gen. Psychiatry<\/i>, <b>57<\/b>, 777\u2013784 (2000).","DOI":"10.1001\/archpsyc.57.8.777"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Bartlett LA, Berg CJ, Shulman HB, Zane SB, Green CA, Whitehead S, Atrash HK. Risk factors for legal induced abortion-related mortality in the United States. <i>Obstet. Gynecol.<\/i>, <b>103<\/b>, 729\u2013737 (2004).","DOI":"10.1097\/01.AOG.0000116260.81570.60"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Momo K, Maeda E, Hattori H, Isozaki H, Takita H, Morohoshi H, Ryu K, Hida N, Sambe T, Shirato N. Descriptive study on a nationwide exploratory questionnaire survey of emergency contraceptive pills and their sexual history and knowledge in Japan. <i>Biol. Pharm. Bull.<\/i>, <b>46<\/b>, 1296\u20131303 (2023).","DOI":"10.1248\/bpb.b23-00268"},{"key":"12","unstructured":"12) Ministry of Health, Labour and Welfare. \u201cVital Statistics of Japan 2024: Monthly Report (Annual Total, Preliminary),\u201d accessed 6 January, 2026."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Kojo T, Ae R, Tsuboi S, Nakamura Y, Kitamura K. Differentials in variables associated with past history of artificial abortion and current contraception by age: results of a randomized national survey in Japan. <i>J. Obstet. Gynaecol. Res.<\/i>, <b>43<\/b>, 516\u2013522 (2017).","DOI":"10.1111\/jog.13246"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Ramer S, Nguyen AT, Hollier LM, Rodenhizer J, Warner L, Whiteman MK. Abortion surveillance\u2014United States, 2022. <i>MMWR Surveill. Summ.<\/i>, <b>73<\/b>, 1\u201328 (2024).","DOI":"10.15585\/mmwr.ss7307a1"},{"key":"15","unstructured":"15) Office for Health Improvement &amp; Disparities. \u201cAbortion statistics, England and Wales: 2021. [updated 2025 Nov 4].\u201d: &lt;https:\/\/www.gov.uk\/government\/statistics\/abortion-statistics-for-england-and-wales-2021\/&gt;, accessed 7 January, 2026."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Scott RH, Bajos N, Slaymaker E, Wellings K, Mercer CH. Understanding differences in conception and abortion rates among under-20 year olds in Britain and France: examining the contribution of social disadvantage. <i>PLOS ONE<\/i>, <b>17<\/b>, 648 (2017).","DOI":"10.1371\/journal.pone.0186412"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Rasch V, Gammeltoft T, Knudsen LB, Tobiassen C, Ginzel A, Kempf L. Induced abortion in Denmark: effect of socio-economic situation and country of birth. <i>Eur. J. Public Health<\/i>, <b>18<\/b>, 144\u2013149 (2008).","DOI":"10.1093\/eurpub\/ckm112"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) V\u00e4is\u00e4nen H. Educational inequalities in repeat abortion: a longitudinal register study in Finland 1975\u20132010. <i>J. Biosoc. Sci.<\/i>, <b>48<\/b>, 820\u2013832 (2016).","DOI":"10.1017\/S002193201600016X"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) P\u00e9rez G, Garc\u00eda-Subirats I, Rodr\u00edguez-Sanz M, D\u00edez E, Borrell C. Trends in inequalities in induced abortion according to educational level among urban women. <i>J. Urban Health<\/i>, <b>87<\/b>, 524\u2013530 (2010).","DOI":"10.1007\/s11524-009-9394-z"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Ghaznavi C, Ueda P, Okuhama A, Sakamoto H. Sexual behaviors among individuals aged 20\u201349 in Japan: initial findings from a quasi-representative national survey, 2022. <i>J. Sex Res.<\/i>, <b>60<\/b>, 317\u2013324 (2023).","DOI":"10.1080\/00224499.2023.2178614"},{"key":"21","unstructured":"21) Japan Family Planning Association. \u201cThe 4th JEX Japan Sex Survey 2020: Summary of Survey Results.\u201d Family Planning Research Center. accessed 6 January, 2026."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Weitzman A. The effects of women\u2019s education on maternal health: evidence from Peru. <i>Soc. Sci. Med.<\/i>, <b>180<\/b>, 1\u20139 (2017).","DOI":"10.1016\/j.socscimed.2017.03.004"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Jones RK, Darroch JE, Henshaw SK. Patterns in the socioeconomic characteristics of women obtaining abortions in 2000-2001. <i>Perspect. Sex. Reprod. Health<\/i>, <b>34<\/b>, 226\u2013235 (2002).","DOI":"10.2307\/3097821"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Tang L, Wu S, Liu D, Temmerman M, Zhang WH. Repeat induced abortion among Chinese women seeking abortion: two cross-sectional studies. <i>Int. J. Environ. Res. Public Health<\/i>, <b>18<\/b>, 4446 (2021).","DOI":"10.3390\/ijerph18094446"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Klutsey EE, Ankomah A. Factors associated with induced abortion at selected hospitals in the Volta Region. <i>Ghana Int. J. Womens Health<\/i>, <b>6<\/b>, 809\u2013816 (2014).","DOI":"10.2147\/IJWH.S62018"}],"container-title":["Biological and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/49\/4\/49_b25-00727\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T03:39:19Z","timestamp":1777088359000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/49\/4\/49_b25-00727\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,23]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1248\/bpb.b25-00727","relation":{},"ISSN":["0918-6158","1347-5215"],"issn-type":[{"value":"0918-6158","type":"print"},{"value":"1347-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,23]]},"article-number":"b25-00727"}}