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Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. <i>Science<\/i>, <b>330<\/b>, 55\u201360 (2010).","DOI":"10.1126\/science.1193270"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Huang JQ, Zhang H, Guo XW, Lu Y, Wang SN, Cheng B, Dong SH, Lyu XL, Li FS, Li YW. Mechanically activated calcium channel PIEZO1 modulates radiation-induced epithelial-mesenchymal transition by forming a positive feedback with TGF-\u03b21. <i>Front. Mol. Biosci.<\/i>, <b>8<\/b>, 725275 (2021).","DOI":"10.3389\/fmolb.2021.725275"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Zhang S, Cao S, Gong M, Zhang W, Zhang W, Zhu Z, Wu S, Yue Y, Qian W, Ma Q, Wang S, Wang Z. Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT\/mTOR signaling. <i>Cancer Biol. 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Involvement of A2B receptor in DNA damage response and radiosensitizing effect of A2B receptor antagonists on mouse B16 melanoma. <i>Biol. Pharm. Bull.<\/i>, <b>43<\/b>, 516\u2013525 (2020).","DOI":"10.1248\/bpb.b19-00976"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Qu P, Zhang H. The dual role of Piezo1 in tumor cells and immune cells: a new target for cancer therapy. <i>Front. Immunol.<\/i>, <b>16<\/b>, 1635388 (2025).","DOI":"10.3389\/fimmu.2025.1635388"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Lopez-Cavestany M, Hahn SB, Hope JM, Reckhorn NT, Greenlee JD, Schwager SC, VanderBurgh JA, Reinhart-King CA, King MR. Matrix stiffness induces epithelial-to-mesenchymal transition <i>via<\/i> Piezo1-regulated calcium flux in prostate cancer cells. <i>iScience<\/i>, <b>26<\/b>, 106275 (2023).","DOI":"10.1016\/j.isci.2023.106275"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) de Los Heros P, Pacheco-Alvarez D, Gamba G. Role of WNK kinases in the modulation of cell volume. <i>Curr. Top. Membr.<\/i>, <b>81<\/b>, 207\u2013235 (2018).","DOI":"10.1016\/bs.ctm.2018.08.002"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Bae C, Sachs F, Gottlieb PA. The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4. <i>Biochemistry<\/i>, <b>50<\/b>, 6295\u20136300 (2011).","DOI":"10.1021\/bi200770q"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Lebon D, Collet L, Djordjevic S, Gomila C, Ouled-Haddou H, Platon J, Demont Y, Marolleau JP, Caulier A, Gar\u00e7on L. PIEZO1 is essential for the survival and proliferation of acute myeloid leukemia cells. <i>Cancer Med.<\/i>, <b>13<\/b>, e6984 (2024).","DOI":"10.1002\/cam4.6984"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Suzuki T, Muraki Y, Hatano N, Suzuki H, Muraki K. PIEZO1 Channel Is a Potential Regulator of Synovial Sarcoma Cell-Viability. <i>Int. J. Mol. 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Chemical activation of the mechanotransduction channel Piezo1. <i>eLife<\/i>, <b>4<\/b>, e07369 (2015).","DOI":"10.7554\/eLife.07369"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Zeng J, Fang Z, Duan J, Zhang Z, Wang Y, Wang Y, Chen L, Wang J, Liu F. Activation of Piezo1 by intracranial hypertension induced neuronal apoptosis <i>via<\/i> activating hippo pathway. <i>CNS Neurosci. Ther.<\/i>, <b>30<\/b>, e14872 (2024).","DOI":"10.1111\/cns.14872"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Jung JU, Stippec S, Cobb MH. Activation of WNK1 signaling through Piezo1. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>122<\/b>, e2513155122 (2025).","DOI":"10.1073\/pnas.2513155122"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Kitabatake K, Kaji T, Tsukimoto M. ATP and ADP enhance DNA damage repair in \u03b3-irradiated BEAS-2B human bronchial epithelial cells through activation of P2X7 and P2Y12 receptors. <i>Toxicol. Appl. 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Chemical activation and mechanical sensitization of Piezo1 enhance trail-mediated apoptosis in glioblastoma cells. <i>ACS Omega<\/i>, <b>8<\/b>, 16975\u201316986 (2023).","DOI":"10.1021\/acsomega.3c00705"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Vasileva VY, Khairullina ZM, Chubinskiy-Nadezhdin VI. Piezo1 activation prevents spheroid formation by malignant melanoma SK-MEL-2 cells. <i>Int. J. Mol. Sci.<\/i>, <b>24<\/b>, 15703 (2023).","DOI":"10.3390\/ijms242115703"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Huang Z, Sun Z, Zhang X, Niu K, Wang Y, Zheng J, Li H, Liu Y. Loss of stretch-activated channels, PIEZOs, accelerates non-small cell lung cancer progression and cell migration. <i>Biosci. Rep.<\/i>, <b>39<\/b>, BSR20181679 (2019).","DOI":"10.1042\/BSR20181679"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Deng J, Li Y, Zhang L, Liao W, Liu T, Shen F. Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA\/ROCK1\/PIP2 signaling pathway. <i>Discov. Oncol.<\/i>, <b>16<\/b>, 787 (2025).","DOI":"10.1007\/s12672-025-02474-7"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Xiong Y, Dong L, Bai Y, Tang H, Li S, Luo D, Liu F, Bai J, Yang S, Song X. Piezo1 activation facilitates ovarian cancer metastasis <i>via<\/i> Hippo\/YAP signaling axis. <i>Channels<\/i>, <b>16<\/b>, 159\u2013166 (2022).","DOI":"10.1080\/19336950.2022.2099381"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Zhou W, Liu X, van Wijnbergen JWM, Yuan L, Liu Y, Zhang C, Jia W. Identification of PIEZO1 as a potential prognostic marker in gliomas. <i>Sci. 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