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Opin.<\/i>, 31<\/b>, 707\u2013721 (2015).","DOI":"10.1185\/03007995.2015.1018989"},{"key":"14","unstructured":"14) WHO, \u201cAntibacterial Agents in Clinical Development: An analysis of the antibacterial clinical development pipeline, including tuberculosis.\u201d: \u2039http:\/\/www.who.int\/medicines\/areas\/rational_use\/antibacterial_agents_clinical_development\/en\/\u203a, 2017."},{"key":"15","unstructured":"15) The Pew Charitable Trusts, \u201cAntibiotics Currently in Global Clinical Development.\u201d: \u2039https:\/\/www.pewtrusts.org\/en\/research-and-analysis\/data-visualizations\/2014\/antibiotics-currently-in-clinical-development\u203a, 2019."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Butler M. S., Blaskovich M. A. T., Cooper M. A., J. Antibiot.<\/i>, 70<\/b>, 3\u201324 (2016).","DOI":"10.1038\/ja.2016.72"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Fernandes P., Martens E., Biochem. 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A., Drugs<\/i>, 76<\/b>, 567\u2013588 (2016).","DOI":"10.1007\/s40265-016-0545-8"},{"key":"26","unstructured":"26) Zhou J., Xiao X.-Y., Plamondon L., Hunt D. K., Clark R. B., Zahler R. B., WO\/2010\/017470 A1 (2010)."},{"key":"27","unstructured":"27) Sutcliffe J. A., WO\/2012\/021829 A1 (2012)."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Ronn M., Zhu Z., Hogan P. C., Zhang W.-Y., Niu J., Katz C. E., Dunwoody N., Gilicky O., Deng Y., Hunt D. K., He M., Chen C.-L., Sun C., Clark R. B., Xiao X.-Y., Org. Process Res. Dev.<\/i>, 17<\/b>, 838\u2013845 (2013).","DOI":"10.1021\/op4000219"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Connors K. P., Housman S. T., Pope J. S., Russomanno J., Salerno E., Shore E., Redican S., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 58<\/b>, 2113\u20132118 (2014).","DOI":"10.1128\/AAC.02036-13"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Solomkin J. S., Ramesh M. 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K., Sun C., Zhao P., WO\/2018\/045084 A1 (2018)."},{"key":"44","unstructured":"44) Sun C., Deng Y., Hunt D., Fyfe C., Kerstein K., Xiao X., Microbe A. S. M., 2017 Sunday-332, New Orleans, LA, U.S.A. (2017)."},{"key":"45","doi-asserted-by":"crossref","unstructured":"45) Falagas M. E., Skalidis T., Vardakas K. Z., Voulgaris G. L., Papanikolaou G., Legakis N., Int. J. Antimicrob. Agents<\/i>, 52<\/b>, 269\u2013271 (2018).","DOI":"10.1016\/j.ijantimicag.2018.03.009"},{"key":"46","unstructured":"46) Fyfe C., Barry R., Close B., Kerstein K., Nordmann P., Newman J., Microbe A. S. M., 2018 Poster-655, Atlanta, GA, U.S.A., 2018."},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Lenhard J. R., Bulman Z. P., Tsuji B. T., Kaye K. S., Antibiotics<\/i>, 8<\/b>, 42 (2019).","DOI":"10.3390\/antibiotics8020042"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) Rice L. B., J. Infect. Dis.<\/i>, 197<\/b>, 1079\u20131081 (2008).","DOI":"10.1086\/533452"},{"key":"49","unstructured":"49) Arends S. J. R., Rhomberg P. R., Lister T., Cotroneo N., Rubio A., Flamm R. K., Mendes R. E., ASM-ESCMID 2018 Poster #80 Lisbon, Portugal, 2018."},{"key":"50","unstructured":"50) Arends S. J. R., Rhomberg P. R., Lister T., Cotroneo N., Rubio A., Flamm R. K., Mendes R. E., ASM-ESCMID 2018 Poster #81 Lisbon, Portugal (2018)."},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Akhoundsadegh N., Belanger C. R., Hancock R. E. W., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00935\u2013e00919 (2019).","DOI":"10.1128\/AAC.00935-19"},{"key":"52","unstructured":"52) Brown P., Boakes S., Duperchy E., Abdulle O., Rivers D., Simonovic M., Singh J., Coleman S., Dawson M. J., ASM Microbe 2019 Poster-793 San Francisco, CA, U.S.A., 2019."},{"key":"53","unstructured":"53) Brown P., Boakes S., Duperchy E., Rivers D., Singh J., Dawson M. J., ASM ESCMID 2018 Poster-145 Lisbon, Portugal, 2018."},{"key":"54","doi-asserted-by":"crossref","unstructured":"54) Brown P., Abbott E., Abdulle O., Boakes S., Coleman S., Divall N., Duperchy E., Moss S., Rivers D., Simonovic M., Singh J., Stanway S., Wilson A., Dawson M. J., ACS Infect. Dis.<\/i>, 5<\/b>, 1645\u20131656 (2019).","DOI":"10.1021\/acsinfecdis.9b00217"},{"key":"55","doi-asserted-by":"crossref","unstructured":"55) Mingeot-Leclercq M.-P., Tulkens P. M., Denamur S., Vaara T., Vaara M., Peptides<\/i>, 35<\/b>, 248\u2013252 (2012).","DOI":"10.1016\/j.peptides.2012.03.033"},{"key":"56","doi-asserted-by":"crossref","unstructured":"56) Vaara M., J. Antimicrob. Chemother.<\/i>, 68<\/b>, 1213\u20131219 (2013).","DOI":"10.1093\/jac\/dkt039"},{"key":"57","unstructured":"57) Lister T., WO\/2017\/197291 A1 (2017)."},{"key":"58","unstructured":"58) Coleman S., Shastri P. N., WO\/2017\/197390 A1 (2017)."},{"key":"59","doi-asserted-by":"crossref","unstructured":"59) Vaara M., Siikanen O., Apajalahti J., Fox J., Frimodt-M\u00f8ller N., He H., Poudyal A., Li J., Nation R. L., Vaara T., Antimicrob. Agents Chemother.<\/i>, 54<\/b>, 3341\u20133346 (2010).","DOI":"10.1128\/AAC.01439-09"},{"key":"60","doi-asserted-by":"crossref","unstructured":"60) Corbett D., Wise A., Langley T., Skinner K., Trimby E., Birchall S., Dorali A., Sandiford S., Williams J., Warn P., Vaara M., Lister T., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e00200\u2013e00217 (2017).","DOI":"10.1128\/AAC.00200-17"},{"key":"61","doi-asserted-by":"crossref","unstructured":"61) Zurawski D. V., Reinhart A. A., Alamneh Y. A., Pucci M. J., Si Y., Abu-Taleb R., Shearer J. P., Demons S. T., Tyner S. D., Lister T., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e01239\u2013e01217 (2017).","DOI":"10.1128\/AAC.01239-17"},{"key":"62","unstructured":"62) Kawasaki H., Kojima N., Fujihira A., Takahashi K., Matsubara F., Matsuoka N., WO\/2016\/035846 A1 (2016)."},{"key":"63","unstructured":"63) Matsubara F., Kurita T., Nagamatsu D., WO\/2016\/035845 A1 (2016)."},{"key":"64","doi-asserted-by":"crossref","unstructured":"64) Ito A., Kohira N., Bouchillon S. K., West J., Rittenhouse S., Sader H. S., Rhomberg P. R., Jones R. N., Yoshizawa H., Nakamura R., Tsuji M., Yamano Y., J. Antimicrob. Chemother.<\/i>, 71<\/b>, 670\u2013677 (2016).","DOI":"10.1093\/jac\/dkv402"},{"key":"65","doi-asserted-by":"crossref","unstructured":"65) Kohira N., West J., Ito A., Ito-Horiyama T., Nakamura R., Sato T., Rittenhouse S., Tsuji M., Yamano Y., Antimicrob. Agents Chemother.<\/i>, 60<\/b>, 729\u2013734 (2016).","DOI":"10.1128\/AAC.01695-15"},{"key":"66","doi-asserted-by":"crossref","unstructured":"66) Karlowsky J. A., Hackel M. A., Tsuji M., Yamano Y., Echols R., Sahm D. F., Int. J. Antimicrob. Agents<\/i>, 53<\/b>, 456\u2013466 (2019).","DOI":"10.1016\/j.ijantimicag.2018.11.007"},{"key":"67","doi-asserted-by":"crossref","unstructured":"67) Matsumoto S., Singley C. M., Hoover J., Nakamura R., Echols R., Rittenhouse S., Tsuji M., Yamano Y., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e00700\u2013e00717 (2017).","DOI":"10.1128\/AAC.00700-17"},{"key":"68","doi-asserted-by":"crossref","unstructured":"68) Hackel M. A., Tsuji M., Yamano Y., Echols R., Karlowsky J. A., Sahm D. F., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e00093\u2013e00017 (2017).","DOI":"10.1128\/AAC.00093-17"},{"key":"69","doi-asserted-by":"crossref","unstructured":"69) Hackel M. A., Tsuji M., Yamano Y., Echols R., Karlowsky J. A., Sahm D. F., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e01968\u2013e01917 (2018).","DOI":"10.1128\/AAC.01968-17"},{"key":"70","doi-asserted-by":"crossref","unstructured":"70) Zhanel G. G., Golden A. 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Agents<\/i>, 52<\/b>, 866\u2013867 (2018).","DOI":"10.1016\/j.ijantimicag.2018.11.005"},{"key":"81","doi-asserted-by":"crossref","unstructured":"81) Portsmouth S., van Veenhuyzen D., Echols R., Machida M., Ferreira J. C. A., Ariyasu M., Tenke P., Nagata T. D., Lancet Infect. Dis.<\/i>, 18<\/b>, 1319\u20131328 (2018).","DOI":"10.1016\/S1473-3099(18)30554-1"},{"key":"82","doi-asserted-by":"crossref","unstructured":"82) Reck F., WO\/2019\/092180 A1 (2019).","DOI":"10.5465\/AMBPP.2019.18162abstract"},{"key":"83","unstructured":"83) Reck F., WO\/2019\/058346 A1 (2019)."},{"key":"84","doi-asserted-by":"crossref","unstructured":"84) Felici A., Amicosante G., Antimicrob. Agents Chemother.<\/i>, 39<\/b>, 192\u2013199 (1995).","DOI":"10.1128\/AAC.39.1.192"},{"key":"85","doi-asserted-by":"crossref","unstructured":"85) Biedenbach D. J., Kazmierczak K., Bouchillon S. K., Sahm D. F., Bradford P. A., Antimicrob. Agents Chemother.<\/i>, 59<\/b>, 4239\u20134248 (2015).","DOI":"10.1128\/AAC.00206-15"},{"key":"86","doi-asserted-by":"crossref","unstructured":"86) Matsuda K., Nakagawa S., Nakano F., Inoue M., Mitsuhashi S., J. Antimicrob. Chemother.<\/i>, 19<\/b>, 753\u2013760 (1987).","DOI":"10.1093\/jac\/19.6.753"},{"key":"87","unstructured":"87) Aulakh V. S., Casarez A., Lin X., Lindvall M., McEnroe G., Moser H. E., Reck F., Tjandra M., Simmons R. L., Yifru A., Zhu Q., U.S. 2015\/0266867 A1 (2015)."},{"key":"88","unstructured":"88) Aubin E., Casarez A., Fisch A., Li Z., Lindvall M., Moser H. E., Mutz M., Reck F., Riebesehl B. U., Schoenhentz M., Sethuraman V., Simmons R. L., WO\/2017\/050218 (2017)."},{"key":"89","doi-asserted-by":"crossref","unstructured":"89) Reck F., Bermingham A., Blais J., et al.<\/i>, Bioorg. Med. Chem. Lett.<\/i>, 28<\/b>, 748\u2013755 (2018).","DOI":"10.1016\/j.bmcl.2018.01.006"},{"key":"90","doi-asserted-by":"crossref","unstructured":"90) Blais J., Lopez S., Li C., Ruzin A., Ranjitkar S., Dean C. R., Leeds J. A., Casarez A., Simmons R. L., Reck F., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e00552\u2013e00518 (2018).","DOI":"10.1128\/AAC.00552-18"},{"key":"91","doi-asserted-by":"crossref","unstructured":"91) Weiss W. J., Pulse M. E., Nguyen P., Growcott E. J., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e02214\u2013e02218 (2019).","DOI":"10.1128\/AAC.02214-18"},{"key":"92","doi-asserted-by":"crossref","unstructured":"92) Jones A. K., Ranjitkar S., Lopez S., Li C., Blais J., Reck F., Dean C. R., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e01202\u2013e01218 (2018).","DOI":"10.1128\/AAC.01202-18"},{"key":"93","unstructured":"93) Dean C. R., Barkan D. T., Bermingham A., et al.<\/i>, Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e01200\u2013e01218 (2018)."},{"key":"94","doi-asserted-by":"crossref","unstructured":"94) Drawz S. M., Bonomo R. A., Clin. Microbiol. Rev.<\/i>, 23<\/b>, 160\u2013201 (2010).","DOI":"10.1128\/CMR.00037-09"},{"key":"95","doi-asserted-by":"crossref","unstructured":"95) Bush K., Bradford P. A., Cold Spring Harb. Perspect. Med.<\/i>, 6<\/b>, a025247 (2016).","DOI":"10.1101\/cshperspect.a025247"},{"key":"96","doi-asserted-by":"crossref","unstructured":"96) Lomovskaya O., Sun D., Rubio-Aparicio D., Nelson K., Tsivkovski R., Griffith D. C., Dudley M. N., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e01443\u2013e01417 (2017).","DOI":"10.1128\/AAC.01443-17"},{"key":"97","doi-asserted-by":"crossref","unstructured":"97) Hecker S. J., Reddy K. R., Totrov M., et al.<\/i>, J. Med. Chem.<\/i>, 58<\/b>, 3682\u20133692 (2015).","DOI":"10.1021\/acs.jmedchem.5b00127"},{"key":"98","doi-asserted-by":"crossref","unstructured":"98) Langley G. W., Cain R., Tyrrell J. M., Hinchliffe P., Calvopi\u00f1a K., Tooke C. L., Widlake E., Dowson C. G., Spencer J., Walsh T. R., Schofield C. J., Brem J., Bioorg. Med. Chem. Lett.<\/i>, 29<\/b>, 1981\u20131984 (2019).","DOI":"10.1016\/j.bmcl.2019.05.031"},{"key":"99","doi-asserted-by":"crossref","unstructured":"99) Dhillon S., Drugs<\/i>, 78<\/b>, 1259\u20131270 (2018).","DOI":"10.1007\/s40265-018-0966-7"},{"key":"100","doi-asserted-by":"crossref","unstructured":"100) Castanheira M., Rhomberg P. R., Flamm R. K., Jones R. N., Antimicrob. Agents Chemother.<\/i>, 60<\/b>, 5454\u20135458 (2016).","DOI":"10.1128\/AAC.00711-16"},{"key":"101","doi-asserted-by":"crossref","unstructured":"101) Zhanel G. G., Lawrence C. K., Adam H., Schweizer F., Zelenitsky S., Zhanel M., Lagac\u00e9-Wiens P. R. S., Walkty A., Denisuik A., Golden A., Gin A. S., Hoban D. J., Lynch J. P. III, Karlowsky J. A., Drugs<\/i>, 78<\/b>, 65\u201398 (2018).","DOI":"10.1007\/s40265-017-0851-9"},{"key":"102","doi-asserted-by":"crossref","unstructured":"102) Zhou M., Yang Q., Lomovskaya O., Sun D., Kudinha T., Xu Z., Zhang G., Chen X., Xu Y., J. Antimicrob. Chemother.<\/i>, 73<\/b>, 2789\u20132796 (2018).","DOI":"10.1093\/jac\/dky251"},{"key":"103","doi-asserted-by":"crossref","unstructured":"103) Bassetti M., Giacobbe D. R., Patel N., Tillotson G., Massey J., Adv. Ther.<\/i>, 36<\/b>, 1771\u20131777 (2019).","DOI":"10.1007\/s12325-019-00981-y"},{"key":"104","unstructured":"104) Jorgensen S. C. J., McDonald P., Mynatt R. P., Pogue J. M., Lerner S. A., Dhar S., Salimnia H., Rybak M. J., J. Antimicrob. Chemother.<\/i>, 73<\/b>, 3529\u20133531 (2018)."},{"key":"105","doi-asserted-by":"crossref","unstructured":"105) Coleman K., Curr. Opin. Microbiol.<\/i>, 14<\/b>, 550\u2013555 (2011).","DOI":"10.1016\/j.mib.2011.07.026"},{"key":"106","unstructured":"106) Comita-Prevoir J., Durand-Reville T. F., Gauthier L., O\u2019donnell J., Romero J., Tommasi R., Verheijen J., Cunera, Wu F., Wu X., Zhang J., Basarab G. S., Moss B., WO\/2018\/053215 A1 (2018)."},{"key":"107","unstructured":"107) McLeod S., Carter N., Moussa S., Mueller J., Tommasi R., Miller A., Microbe A. S. M., 2019 Sunday-AAR-714 San Francisco, CA, U.S.A. (2019)."},{"key":"108","doi-asserted-by":"crossref","unstructured":"108) Todd W. M., Int. J. Antimicrob. Agents<\/i>, 4<\/b>, 37\u201362 (1994).","DOI":"10.1016\/0924-8579(94)90062-0"},{"key":"109","unstructured":"109) O\u2019Donnell J., Chen A., Tanudra A., Mueller J., Tommasi R., Miller A., Carter N., McLeod S., Comita-Prevoir J., Durand-R\u00e9ville T., Microbe A. S. M., 2017 Session-198 Saturday-278, New Orleans, LA, U.S.A. (2017)."},{"key":"110","unstructured":"110) McLeod S., Carter N., Hackel M., Badal R., Mueller J., Tommasi R., Miller A., Microbe A. S. M., 2018 Friday-603 Atlanta, GA U.S.A. (2018)."},{"key":"111","doi-asserted-by":"crossref","unstructured":"111) Rizk M. L., Rhee E. G., Jumes P. A., Gotfried M. H., Zhao T., Mangin E., Bi S., Chavez-Eng C. M., Zhang Z., Butterton J. R., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e01411\u2013e01417 (2018).","DOI":"10.1128\/AAC.01411-17"},{"key":"112","doi-asserted-by":"crossref","unstructured":"112) Lucasti C., Vasile L., Sandesc D., Venskutonis D., McLeroth P., Lala M., Rizk M. L., Brown M. L., Losada M. C., Pedley A., Kartsonis N. A., Paschke A., Antimicrob. Agents Chemother.<\/i>, 60<\/b>, 6234\u20136243 (2016).","DOI":"10.1128\/AAC.00633-16"},{"key":"113","unstructured":"113) Lyon J. A., Drug Intell. Clin. Pharm.<\/i>, 19<\/b>, 895\u2013899 (1985)."},{"key":"114","doi-asserted-by":"crossref","unstructured":"114) Livermore D. M., Jamrozy D., Mushtaq S., Nichols W. W., Young K., Woodford N., J. Antimicrob. Chemother.<\/i>, 72<\/b>, 3342\u20133348 (2017).","DOI":"10.1093\/jac\/dkx298"},{"key":"115","doi-asserted-by":"crossref","unstructured":"115) Tooke C. L., Hinchliffe P., Lang P. A., Mulholland A. J., Brem J., Schofield C. J., Spencer J., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00564\u2013e00519 (2019).","DOI":"10.1128\/AAC.00564-19"},{"key":"116","doi-asserted-by":"crossref","unstructured":"116) Lob S. H., Hackel M. A., Kazmierczak K. M., Young K., Motyl M. R., Karlowsky J. A., Sahm D. F., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e02209\u2013e02216 (2017).","DOI":"10.1128\/AAC.02209-16"},{"key":"117","doi-asserted-by":"crossref","unstructured":"117) Karlowsky J. A., Lob S. H., Kazmierczak K. M., Hawser S. P., Magnet S., Young K., Motyl M. R., Sahm D. F., J. Antimicrob. Chemother.<\/i>, 73<\/b>, 1872\u20131879 (2018).","DOI":"10.1093\/jac\/dky107"},{"key":"118","doi-asserted-by":"crossref","unstructured":"118) Powles M. A., Galgoci A., Misura A., Colwell L., Dingley K. H., Tang W., Wu J., Blizzard T., Motyl M., Young K., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e02577\u2013e02517 (2018).","DOI":"10.1128\/AAC.02577-17"},{"key":"119","unstructured":"119) Wu J., Racine F., Wismer M. K., Young K., Carr D. M., Xiao J. C., Katwaru R., Si Q., Harradine P., Motyl M., Bhagunde P. R., Rizk M. L., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e02323\u2013e02317 (2018)."},{"key":"120","unstructured":"120) Blizzard T. A., Chen H., Kim S., et al.<\/i>, Bioorg. Med. Chem. Lett.<\/i>, 24<\/b>, 780\u2013785 (2014)."},{"key":"121","doi-asserted-by":"crossref","unstructured":"121) Liu Z., Yasuda N., Simeone M., Reamer R. A., J. Org. Chem.<\/i>, 79<\/b>, 11792\u201311796 (2014).","DOI":"10.1021\/jo502319z"},{"key":"122","doi-asserted-by":"crossref","unstructured":"122) Sims M., Mariyanovski V., McLeroth P., Akers W., Lee Y.-C., Brown M. L., Du J., Pedley A., Kartsonis N. A., Paschke A., J. Antimicrob. Chemother.<\/i>, 72<\/b>, 2616\u20132626 (2017).","DOI":"10.1093\/jac\/dkx139"},{"key":"123","doi-asserted-by":"crossref","unstructured":"123) Morinaka A., Tsutsumi Y., Yamada M., Suzuki K., Watanabe T., Abe T., Furuuchi T., Inamura S., Sakamaki Y., Mitsuhashi N., Ida T., Livermore D. M., J. Antimicrob. Chemother.<\/i>, 70<\/b>, 2779\u20132786 (2015).","DOI":"10.1093\/jac\/dkv166"},{"key":"124","doi-asserted-by":"crossref","unstructured":"124) Livermore D. M., Warner M., Mushtaq S., Woodford N., Antimicrob. Agents Chemother.<\/i>, 60<\/b>, 554\u2013560 (2016).","DOI":"10.1128\/AAC.02184-15"},{"key":"125","unstructured":"125) Tadiparthi R., Patil V. J., Dixit P., Patel M. V., WO\/2016\/120752 A1 (2016)."},{"key":"126","unstructured":"126) Bhagwat S., Patel M. V., WO\/2016\/151543 A1 (2016)."},{"key":"127","doi-asserted-by":"crossref","unstructured":"127) Livermore D. M., Mushtaq S., Warner M., Woodford N., J. Antimicrob. Chemother.<\/i>, 70<\/b>, 3032\u20133041 (2015).","DOI":"10.1093\/jac\/dkv239"},{"key":"128","doi-asserted-by":"crossref","unstructured":"128) Mushtaq S., Vickers A., Woodford N., Haldimann A., Livermore D. M., J. Antimicrob. Chemother.<\/i>, 74<\/b>, 953\u2013960 (2019).","DOI":"10.1093\/jac\/dky522"},{"key":"129","doi-asserted-by":"crossref","unstructured":"129) Baldwin C. M., Lyseng-Williamson K. A., Keam S. J., Drugs<\/i>, 68<\/b>, 803\u2013838 (2008).","DOI":"10.2165\/00003495-200868060-00006"},{"key":"130","doi-asserted-by":"crossref","unstructured":"130) Monogue M. L., Giovagnoli S., Bissantz C., Zampaloni C., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e02596\u2013e02517 (2018).","DOI":"10.1128\/AAC.02596-17"},{"key":"131","doi-asserted-by":"crossref","unstructured":"131) Asempa T. E., Motos A., Abdelraouf K., Bissantz C., Zampaloni C., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e02382\u2013e02318 (2019).","DOI":"10.1128\/AAC.02382-18"},{"key":"132","doi-asserted-by":"crossref","unstructured":"132) Bryson H. M., Brogden R. N., Drugs<\/i>, 47<\/b>, 506\u2013535 (1994).","DOI":"10.2165\/00003495-199447030-00008"},{"key":"133","doi-asserted-by":"crossref","unstructured":"133) Barnes M. D., Taracila M. A., Good C. E., Bajaksouzian S., Rojas L. J., van Duin D., Kreiswirth B. N., Jacobs M. R., Haldimann A., Papp-Wallace K. M., Bonomo R. A., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00432\u2013e00419 (2019).","DOI":"10.1128\/AAC.00432-19"},{"key":"134","doi-asserted-by":"crossref","unstructured":"134) Barradell L. B., Bryson H. M., Drugs<\/i>, 47<\/b>, 471\u2013505 (1994).","DOI":"10.2165\/00003495-199447030-00007"},{"key":"135","unstructured":"135) Burns C., J., Daigle D., Liu B., Mcgarry D., Pevear D. C., Trout R. E. L., WO\/2014\/089365 A1 (2014)."},{"key":"136","unstructured":"136) Burns C. J., Pevear D. C., Xerri L., Henkel T., Mcgarry D., Rosen L., Brenner G., Arlin J.-B., Fernandez Casares A., WO\/2018\/165048 A1 (2018)."},{"key":"137","doi-asserted-by":"crossref","unstructured":"137) Krajnc A., Brem J., Hinchliffe P., Calvopi\u00f1a K., Panduwawala T. D., Lang P. A., Kamps J. J. A. G., Tyrrell J. M., Widlake E., Saward B. G., Walsh T. R., Spencer J., Schofield C. J., J. Med. Chem.<\/i>, 62<\/b>, 8544\u20138556 (2019).","DOI":"10.1021\/acs.jmedchem.9b00911"},{"key":"138","doi-asserted-by":"crossref","unstructured":"138) Daigle D., Hamrick J., Chatwin C., Kurepina N., Kreiswirth B. N., Shields R. K., Oliver A., Clancy C. J., Nguyen M.-H., Pevear D., Xerri L., Open Forum Infect. Dis.<\/i>, 5<\/b> (suppl. 1), S419\u2013S420 (2018).","DOI":"10.1093\/ofid\/ofy210.1201"},{"key":"139","unstructured":"139) Hackel M., Sahm D., ECCMID 2019 Poster-1175 Amsterdam, Netherlands (2019)."},{"key":"140","unstructured":"140) Hackel M., Sahm D., Microbe A. S. M., 2019 Sunday-AAR-772 San Francisco, CA, U.S.A. (2019)."},{"key":"141","unstructured":"141) Piccirilli A., Segatore B., Daigle D., Amicosante G., Perilli M., ECCMID 2019 Poster-1178 Amsterdam, Netherlands (2019)."},{"key":"142","doi-asserted-by":"crossref","unstructured":"142) Preston R. A., Mamikonyan G., DeGraff S., Chiou J., Kemper C. J., Xu A., Mastim M., Yeole R., Chavan R., Patel A., Friedland H. D., Bhatia A., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e01484\u2013e01418 (2019).","DOI":"10.1128\/AAC.00873-19"},{"key":"143","doi-asserted-by":"crossref","unstructured":"143) Rodvold K. A., Gotfried M. H., Chugh R., Gupta M., Patel A., Chavan R., Yeole R., Friedland H. D., Bhatia A., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e00682\u2013e00618 (2018).","DOI":"10.1128\/AAC.00682-18"},{"key":"144","doi-asserted-by":"crossref","unstructured":"144) Sader H. S., Rhomberg P. R., Flamm R. K., Jones R. N., Castanheira M., J. Antimicrob. Chemother.<\/i>, 72<\/b>, 1696\u20131703 (2017).","DOI":"10.1093\/jac\/dkx050"},{"key":"145","doi-asserted-by":"crossref","unstructured":"145) Livermore D. M., Mushtaq S., Warner M., Vickers A., Woodford N., J. Antimicrob. Chemother.<\/i>, 72<\/b>, 1373\u20131385 (2017).","DOI":"10.1093\/jac\/dkw593"},{"key":"146","doi-asserted-by":"crossref","unstructured":"146) Moya B., Barcelo I. M., Cabot G., Torrens G., Palwe S., Joshi P., Umarkar K., Takalkar S., Periasamy H., Bhagwat S., Patel M., Bou G., Oliver A., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00128\u2013e00119 (2019).","DOI":"10.1128\/AAC.00128-19"},{"key":"147","doi-asserted-by":"crossref","unstructured":"147) Papp-Wallace K. M., Nguyen N. Q., Jacobs M. R., Bethel C. R., Barnes M. D., Kumar V., Bajaksouzian S., Rudin S. D., Rather P. N., Bhavsar S., Ravikumar T., Deshpande P. K., Patil V., Yeole R., Bhagwat S. S., Patel M. V., van den Akker F., Bonomo R. A., J. Med. Chem.<\/i>, 61<\/b>, 4067\u20134086 (2018).","DOI":"10.1021\/acs.jmedchem.8b00091"},{"key":"148","doi-asserted-by":"crossref","unstructured":"148) Bhagwat S. S., Periasamy H., Takalkar S. S., Palwe S. R., Khande H. N., Patel M. V., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e02146\u2013e02118 (2019).","DOI":"10.1128\/AAC.02146-18"},{"key":"149","doi-asserted-by":"crossref","unstructured":"149) Moya B., Barcelo I. M., Bhagwat S., Patel M., Bou G., Papp-Wallace K. M., Bonomo R. A., Oliver A., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e01238\u2013e01217 (2017).","DOI":"10.1128\/AAC.01238-17"},{"key":"150","doi-asserted-by":"crossref","unstructured":"150) Avery L. M., Abdelraouf K., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e00948\u2013e00918 (2018).","DOI":"10.1128\/AAC.00948-18"},{"key":"151","doi-asserted-by":"crossref","unstructured":"151) Almarzoky Abuhussain S. S., Avery L. M., Abdelraouf K., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e01931\u2013e01918 (2019).","DOI":"10.1128\/AAC.01931-18"},{"key":"152","doi-asserted-by":"crossref","unstructured":"152) Thomson K. S., AbdelGhani S., Snyder J. W., Thomson G. K., Antibiotics<\/i>, 8<\/b>, 32 (2019).","DOI":"10.3390\/antibiotics8010032"},{"key":"153","doi-asserted-by":"crossref","unstructured":"153) Sader H. S., Castanheira M., Huband M., Jones R. N., Flamm R. K., Antimicrob. Agents Chemother.<\/i>, 61<\/b>, e00072\u2013e00017 (2017).","DOI":"10.1128\/AAC.00072-17"},{"key":"154","doi-asserted-by":"crossref","unstructured":"154) Khan Z., Iregui A., Landman D., Quale J., J. Antimicrob. Chemother.<\/i>, 74<\/b>, 2938\u20132942 (2019).","DOI":"10.1093\/jac\/dkz294"},{"key":"155","doi-asserted-by":"crossref","unstructured":"155) Monogue M. L., Tabor-Rennie J., Abdelraouf K., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00233\u2013e00219 (2019).","DOI":"10.1128\/AAC.00233-19"},{"key":"156","unstructured":"156) Faini A., Forzatti M., Fogliato G., Biondi S., WO\/2015\/173378 A2 (2015)."},{"key":"157","unstructured":"157) Lamonica A., Forzatti M., Biondi S., WO\/2015\/067787 A1 (2015)."},{"key":"158","doi-asserted-by":"crossref","unstructured":"158) Endimiani A., Perez F., Bonomo R. A., Expert Rev. Anti Infect. Ther.<\/i>, 6<\/b>, 805\u2013824 (2008).","DOI":"10.1586\/14787210.6.6.805"},{"key":"159","doi-asserted-by":"crossref","unstructured":"159) Papp-Wallace K. M., Bethel C. R., Caillon J., Barnes M. D., Potel G., Bajaksouzian S., Rutter J. D., Reghal A., Shapiro S., Taracila M. A., Jacobs M. R., Bonomo R. A., Jacqueline C., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00105\u2013e00119 (2019).","DOI":"10.1128\/AAC.00105-19"},{"key":"160","doi-asserted-by":"crossref","unstructured":"160) Morrissey I., Magnet S., Hawser S., Shapiro S., Knechtle P., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00514\u2013e00519 (2019).","DOI":"10.1128\/AAC.00514-19"},{"key":"161","doi-asserted-by":"crossref","unstructured":"161) Papp-Wallace K. M., Bethel C. R., Barnes M. D., Rutter J. D., Taracila M. A., Bajaksouzian S., Jacobs M. R., Bonomo R. A., Open Forum Infect. Dis.<\/i>, 4<\/b> (Suppl. 1), S375 (2017).","DOI":"10.1093\/ofid\/ofx163.924"},{"key":"162","doi-asserted-by":"crossref","unstructured":"162) Crandon J. L., Nicolau D. P., Pathogens<\/i>, 4<\/b>, 620\u2013625 (2015).","DOI":"10.3390\/pathogens4030620"},{"key":"163","doi-asserted-by":"crossref","unstructured":"163) Crandon J. L., Nicolau D. P., Antimicrob. Agents Chemother.<\/i>, 59<\/b>, 2688\u20132694 (2015).","DOI":"10.1128\/AAC.00033-15"},{"key":"164","doi-asserted-by":"crossref","unstructured":"164) Belley A., Huband M. D., Fedler K. A., Watters A. A., Flamm R. K., Shapiro S., Knechtle P., J. Clin. Microbiol.<\/i>, 57<\/b>, e00607\u2013e00619 (2019).","DOI":"10.1128\/JCM.00607-19"},{"key":"165","doi-asserted-by":"crossref","unstructured":"165) Isler B., Doi Y., Bonomo R. A., Paterson D. L., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e01110\u2013e01118 (2019).","DOI":"10.1128\/AAC.01110-18"},{"key":"166","doi-asserted-by":"crossref","unstructured":"166) Kostyanev T., Bonten M. J. M., O\u2019Brien S., Steel H., Ross S., Fran\u00e7ois B., Tacconelli E., Winterhalter M., Stavenger R. A., Karl\u00e9n A., Harbarth S., Hackett J., Jafri H. S., Vuong C., MacGowan A., Witschi A., Angyalosi G., Elborn J. S., deWinter R., Goossens H., J. Antimicrob. Chemother.<\/i>, 71<\/b>, 290\u2013295 (2016).","DOI":"10.1093\/jac\/dkv339"},{"key":"167","doi-asserted-by":"crossref","unstructured":"167) O\u2019Connor S., Lam L. K. T., Jones N. D., Chaney M. O., J. Org. Chem.<\/i>, 41<\/b>, 2087\u20132092 (1976).","DOI":"10.1021\/jo00874a003"},{"key":"168","doi-asserted-by":"crossref","unstructured":"168) Takahashi Y., Igarashi M., J. Antibiot.<\/i>, 71<\/b>, 4\u201314 (2018).","DOI":"10.1038\/ja.2017.117"},{"key":"169","unstructured":"169) Takahashi Y., Umemura E., Ida T., Igarashi M., WO\/2017\/018528 (2017)."},{"key":"170","unstructured":"170) Umemura E., Takahashi Y., Igarashi M., Hayashi C., Shibasaki M., Yamada K., Ida T., Yonezawa M., Ago K., Microbe A. S. M., 2017, Poster Sunday-335 New Orleans, LA, U.S.A. (2017)."},{"key":"171","doi-asserted-by":"crossref","unstructured":"171) Martin-Loeches I., Dale G. E., Torres A., Expert Rev. Anti Infect. Ther.<\/i>, 16<\/b>, 259\u2013268 (2018).","DOI":"10.1080\/14787210.2018.1441024"},{"key":"172","doi-asserted-by":"crossref","unstructured":"172) Wach A., Dembowsky K., Dale G. E., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e02355\u2013e02317 (2018).","DOI":"10.1128\/AAC.02355-17"},{"key":"173","doi-asserted-by":"crossref","unstructured":"173) Dale G. E., Halabi A., Petersen-Sylla M., Wach A., Zwingelstein C., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e00490\u2013e00418 (2018).","DOI":"10.1128\/AAC.00490-18"},{"key":"174","doi-asserted-by":"crossref","unstructured":"174) Srinivas N., Jetter P., Ueberbacher B. J., et al.<\/i>, Science<\/i>, 327<\/b>, 1010\u20131013 (2010).","DOI":"10.1126\/science.1182749"},{"key":"175","doi-asserted-by":"crossref","unstructured":"175) Werneburg M., Zerbe K., Juhas M., Bigler L., Stalder U., Kaech A., Ziegler U., Obrecht D., Eberl L., Robinson J. A., ChemBioChem<\/i>, 13<\/b>, 1767\u20131775 (2012).","DOI":"10.1002\/cbic.201200276"},{"key":"176","doi-asserted-by":"crossref","unstructured":"176) Sader H. S., Dale G. E., Rhomberg P. R., Flamm R. K., Antimicrob. Agents Chemother.<\/i>, 62<\/b>, e00311\u2013e00318 (2018).","DOI":"10.1128\/AAC.00311-18"},{"key":"177","doi-asserted-by":"crossref","unstructured":"177) Sader H. S., Flamm R. K., Dale G. E., Rhomberg P. R., Castanheira M., J. Antimicrob. Chemother.<\/i>, 73<\/b>, 2400\u20132404 (2018).","DOI":"10.1093\/jac\/dky227"},{"key":"178","doi-asserted-by":"crossref","unstructured":"178) Romano K. P., Warrier T., Poulsen B. E., Nguyen P. H., Loftis A. R., Saebi A., Pentelute B. L., Hung D. T., Antimicrob. Agents Chemother.<\/i>, 63<\/b>, e00511\u2013e00519 (2019).","DOI":"10.1128\/AAC.00511-19"}],"container-title":["Chemical and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/68\/3\/68_c19-00842\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T01:11:26Z","timestamp":1665969086000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/68\/3\/68_c19-00842\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":178,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1248\/cpb.c19-00842","relation":{},"ISSN":["0009-2363","1347-5223"],"issn-type":[{"value":"0009-2363","type":"print"},{"value":"1347-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,1]]}}}