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B., Altomare D., Thal D. R., Ribaldi F., van der Kant R., Ossenkoppele R., Blennow K., Cummings J., van Duijn C., Nilsson P. M., Dietrich P.-Y., Scheltens P., Dubois B., <i>Nat. Rev. Neurosci.<\/i>, <b>23<\/b>, 53\u201366 (2022).","DOI":"10.1038\/s41583-021-00533-w"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Ogunmokun G., Dewanjee S., Chakraborty P., Valupadas C., Chaudhary A., Kolli V., Anand U., Vallamkondu J., Goel P., Paluru H. P. R., Gill K. D., Reddy P. H., Feo V. D., Kandimalla R., <i>Cells<\/i>, <b>10<\/b>, 2790 (2021).","DOI":"10.3390\/cells10102790"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Katsuse O., Lin W.-L., Lewis J., Hutton M. L., Dickson D. W., <i>Neurosci. Lett.<\/i>, <b>409<\/b>, 95\u201399 (2006).","DOI":"10.1016\/j.neulet.2006.09.021"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Walsh D. M., Klyubin I., Fadeeva J. V., Cullen W. K., Anwyl R., Wolfe M. S., Rowan M. J., Selkoe D. 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Neurol.<\/i>, <b>15<\/b>, 73\u201388 (2019).","DOI":"10.1038\/s41582-018-0116-6"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) van Dyck C. H., Swanson C. J., Aisen P., Bateman R. J., Chen C., Gee M., Kanekiyo M., Li D., Reyderman L., Cohen S., Froelich L., Katayama S., Sabbagh M., Vellas B., Watson D., Dhadda S., Irizarry M., Kramer L. D., Iwatsubo T., <i>N. Engl. J. Med.<\/i>, <b>388<\/b>, 9\u201321 (2023).","DOI":"10.1056\/NEJMoa2212948"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Guan Z., Giustetto M., Lomvardas S., Kim J.-H., Miniaci M. C., Schwartz J. H., Thanos D., Kandel E. R., <i>Cell<\/i>, <b>111<\/b>, 483\u2013493 (2002).","DOI":"10.1016\/S0092-8674(02)01074-7"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Alarc\u00f3 J. M., Malleret G. L., Touzani K., Vronskaya S., Ishii S., Kandel E. R., Barco A., <i>Neuron<\/i>, <b>42<\/b>, 947\u2013959 (2004).","DOI":"10.1016\/j.neuron.2004.05.021"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Korzus E., Rosenfeld M. G., Mayford M., <i>Neuron<\/i>, <b>42<\/b>, 961\u2013972 (2004).","DOI":"10.1016\/j.neuron.2004.06.002"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Guan J.-S., Haggarty S. J., Giacometti E., Dannenberg J.-H., Joseph N., Gao J., Nieland T. J. F., Zhou Y., Wang X., Mazitschek R., Bradner J. E., DePinho R. A., Jaenisch R., Tsai L.-H., <i>Nature<\/i> (London), <b>459<\/b>, 55\u201360 (2009).","DOI":"10.1038\/nature07925"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Gr\u00e4ff J., Rei D., Guan J.-S., Wang W.-Y., Seo J., Hennig K. M., Nieland T. J. F., Fass D. M., Kao P. F., Kahn M., Su S. C., Samiei A., Joseph N., Haggarty S. J., Delalle I., Tsai L.-H., <i>Nature<\/i> (London), <b>483<\/b>, 222\u2013226 (2012).","DOI":"10.1038\/nature10849"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Basavarajappa B. S., Subbanna S., <i>Int. J. Mol. Sci.<\/i>, <b>22<\/b>, 4654 (2021).","DOI":"10.3390\/ijms22094654"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Nikkar R., Esmaeili-bandboni A., Badrikoohi M., Babaei P., <i>Metab. Brain Dis.<\/i>, <b>37<\/b>, 1119\u20131131 (2022).","DOI":"10.1007\/s11011-022-00940-7"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Zhu X., Wang S., Yu L., Jin J., Ye X., Liu Y., Xu Y., <i>Aging Cell<\/i>, <b>16<\/b>, 1073\u20131082 (2017).","DOI":"10.1111\/acel.12642"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Baba R., Matsuda S., Maeda R., Murakami K., Yamamoto Y., Nakatani A., Kimura H., <i>ACS Chem. Neurosci.<\/i>, <b>13<\/b>, 313\u2013321 (2022).","DOI":"10.1021\/acschemneuro.1c00713"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Benito E., Ramachandran B., Schroeder H., Schmidt G., Urbanke H., Burkhardt S., Capece V., Dean C., Fischer A., <i>Transl. Psychiatry<\/i>, <b>7<\/b>, e1239 (2017).","DOI":"10.1038\/tp.2017.202"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Bondarev A. D., Attwood M. M., Jonsson J., Chubarev V. N., Tarasov V. V., Schi\u00f6th H. B., <i>Br. J. Clin. Pharmacol.<\/i>, <b>87<\/b>, 4577\u20134597 (2021).","DOI":"10.1111\/bcp.14889"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Noce B., Bello E. D., Fioravanti R., Mai A., <i>Front. Pharmacol.<\/i>, <b>14<\/b>, 1120911 (2023).","DOI":"10.3389\/fphar.2023.1120911"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Glozak M. A., Sengupta N., Zhang X., Seto E., <i>Gene<\/i>, <b>363<\/b>, 15\u201323 (2005).","DOI":"10.1016\/j.gene.2005.09.010"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Levenson J. M., O\u2019Riordan K. J., Brown K. D., Trinh M. A., Molfese D. L., Sweatt J. D., <i>J. Biol. Chem.<\/i>, <b>279<\/b>, 40545\u201340559 (2004).","DOI":"10.1074\/jbc.M402229200"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Govindarajan N., Rao P., Burkhardt S., Sananbenesi F., Schl\u00fcter O. M., Bradke F., Lu J., Fischer A., <i>EMBO Mol. Med.<\/i>, <b>5<\/b>, 52\u201363 (2013).","DOI":"10.1002\/emmm.201201923"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Silva D. F., Esteves A. R., Oliveira C. R., Cardoso S. M., <i>Mol. Neurobiol.<\/i>, <b>54<\/b>, 4021\u20134040 (2017).","DOI":"10.1007\/s12035-016-9951-x"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Gryder B. E., Sodji Q. H., Oyelere A. K., <i>Future Med. Chem.<\/i>, <b>4<\/b>, 505\u2013524 (2012).","DOI":"10.4155\/fmc.12.3"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Ho T. C. S., Chan A. H. Y., Ganesan A., <i>J. Med. Chem.<\/i>, <b>63<\/b>, 12460\u201312484 (2020).","DOI":"10.1021\/acs.jmedchem.0c00830"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Wang C. Y., Lee L. H., <i>Antimicrob. Agents Chemother.<\/i>, <b>11<\/b>, 753\u2013755 (1977).","DOI":"10.1128\/AAC.11.4.753"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Kim M., Kizibash S. H., Laramy J. K., Gampa G., Parrish K. E., Sarkaria J. N., Elmquist W. F., <i>Pharm. Res.<\/i>, <b>35<\/b>, 177 (2018).","DOI":"10.1007\/s11095-018-2455-9"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Copeland R. A., Pompliano D. L., Meek T. D., <i>Nat. Rev. Drug Discov.<\/i>, <b>5<\/b>, 730\u2013739 (2006).","DOI":"10.1038\/nrd2082"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Wagner F. F., Zhang Y.-L., Fass D. M., <i>et al.<\/i>, <i>Chem. Sci.<\/i> (Camb.), <b>6<\/b>, 804\u2013815 (2015).","DOI":"10.1039\/C4SC02130D"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Kim D., Frank C. L., Dobbin M. M., Tsunemoto R. K., Tu W., Peng P. L., Guan J.-S., Lee B.-H., Moy L. Y., Giusti P., Broodie N., Mazitschek R., Delalle I., Haggarty S. J., Neve R. L., Lu Y., Tsai L.-H., <i>Neuron<\/i>, <b>60<\/b>, 803\u2013817 (2008).","DOI":"10.1016\/j.neuron.2008.10.015"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Mishima H., Itoh Y., Kurohara T., Suzuki T., Asada N., Kusakabe K., Okamoto Y., <i>J. Comput. Chem.<\/i>, <b>44<\/b>, 1604\u20131609 (2023).","DOI":"10.1002\/jcc.27111"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Fuller N. O., Pirone A., Lynch B. A., Hewitt M. C., Quinton M. S., McKee T. D., Ivarsson M., <i>ACS Chem. Neurosci.<\/i>, <b>10<\/b>, 1729\u20131743 (2019).","DOI":"10.1021\/acschemneuro.8b00620"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Itoh Y., Takada Y., Yamashita Y., Suzuki T., <i>Curr. Opin. Chem. Biol.<\/i>, <b>67<\/b>, 102130 (2022).","DOI":"10.1016\/j.cbpa.2022.102130"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Oakley H., Cole S. L., Logan S., Maus E., Shao P., Craft J., Guillozet-Bongaarts A., Ohno M., Disterhoft J., Eldik L. V., Berry R., Vassar R., <i>J. Neurosci.<\/i>, <b>26<\/b>, 10129\u201310140 (2006).","DOI":"10.1523\/JNEUROSCI.1202-06.2006"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Tamanini E., Miyamura S., Buck I. M., <i>et al.<\/i>, <i>ACS Med. Chem. Lett.<\/i>, <b>13<\/b>, 1591\u20131597 (2022).","DOI":"10.1021\/acsmedchemlett.2c00272"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Mottamal M., Zheng S., Huang T. L., Wang G., <i>Molecules<\/i>, <b>20<\/b>, 3898\u20133941 (2015).","DOI":"10.3390\/molecules20033898"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) Moreno-Yruela C., Olsen C. A., <i>ACS Med. Chem. Lett.<\/i>, <b>13<\/b>, 779\u2013785 (2022).","DOI":"10.1021\/acsmedchemlett.1c00702"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Janczura K. J., Volmar C.-H., Sartor G. C., Rao S. J., Ricciardi N. R., Lambert G., Brothers S. P., Wahlestedt C., <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>115<\/b>, E11148\u2013E11157 (2018).","DOI":"10.1073\/pnas.1805436115"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41) Suzuki T., Kasuya Y., Itoh Y., Ota Y., Zhan P., Asamitsu K., Nakagawa H., Okamoto T., Miyata N., <i>PLOS ONE<\/i>, <b>8<\/b>, e68669 (2013).","DOI":"10.1371\/journal.pone.0068669"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42) Uchida S., Teubner B. J. W., Hevi C., Hara K., Kobayashi A., Dave R. M., Shintaku T., Jaikhan P., Yamagata H., Suzuki T., Watanabe Y., Zakharenko S. S., Shumyatsky G. P., <i>Cell Rep.<\/i>, <b>18<\/b>, 352\u2013366 (2017).","DOI":"10.1016\/j.celrep.2016.12.052"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43) Pulya S., Mahale A., Bobde Y., Routholla G., Patel T., Swati, Biswas S., Sharma V., Kulkarni O. P., Ghosh B., <i>ACS Chem. Neurosci.<\/i>, <b>12<\/b>, 883\u2013892 (2021).","DOI":"10.1021\/acschemneuro.0c00721"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44) Onishi T., Maeda R., Terada M., Sato S., Fujii T., Ito M., Hashikami K., Kawamoto T., Tanaka M., <i>Sci. Rep.<\/i>, <b>11<\/b>, 15423 (2021).","DOI":"10.1038\/s41598-021-94923-w"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45) Ding H., Dolan P. J., Johnson G. V. W., <i>J. Neurochem.<\/i>, <b>106<\/b>, 2119\u20132130 (2008).","DOI":"10.1111\/j.1471-4159.2008.05564.x"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46) Brindisi M., Saraswati A. P., Brogi S., Gemma S., Butini S., Campiani G., <i>J. Med. Chem.<\/i>, <b>63<\/b>, 23\u201339 (2020).","DOI":"10.1021\/acs.jmedchem.9b00924"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Portran D., Schaedel L., Xu Z., Th\u00e9ry M., Nachury M. V., <i>Nat. Cell Biol.<\/i>, <b>19<\/b>, 391\u2013398 (2017).","DOI":"10.1038\/ncb3481"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) Suzuki T., Khan M. N. A., Sawada H., Imai E., Itoh Y., Yamatsuta K., Tokuda N., Takeuchi J., Seko T., Nakagawa H., Miyata N., <i>J. Med. Chem.<\/i>, <b>55<\/b>, 5760\u20135773 (2012).","DOI":"10.1021\/jm3002108"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49) Jayasena T., Poljak A., Braidy N., Zhong L., Rowlands B., Muenchhoff J., Grant R., Smythe G., Teo C., Raftery M., Sachdev P., <i>Sci. Rep.<\/i>, <b>6<\/b>, 35391 (2016).","DOI":"10.1038\/srep35391"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50) Diaz-Perdigon T., Belloch F. B., Ricobaraza A., Elboray E. E., Suzuki T., Tordera R. M., Puerta E., <i>Neuropsychopharmacology<\/i>, <b>45<\/b>, 347\u2013357 (2020).","DOI":"10.1038\/s41386-019-0503-8"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Tomobe K., Nomura Y., <i>Neurochem. Res.<\/i>, <b>34<\/b>, 660\u2013669 (2009).","DOI":"10.1007\/s11064-009-9923-x"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52) Shi Y., Lan F., Matson C., Mulligan P., Whetstine J. R., Cole P. A., Casero R. A., Shi Y., <i>Cell<\/i>, <b>119<\/b>, 941\u2013953 (2004).","DOI":"10.1016\/j.cell.2004.12.012"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53) Karasulu B., Patil M., Thiel W., <i>J. Am. Chem. Soc.<\/i>, <b>135<\/b>, 13400\u201313413 (2013).","DOI":"10.1021\/ja403582u"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54) Maes T., Mascar\u00f3 C., Rotllant D., Lufino M. M. P., Estiarte A., Guibourt N., Cavalcanti F., Gri\u00f1an-Ferr\u00e9 C., Pall\u00e0s M., Nadal R., Armario A., Ferrer I., Ortega A., Valls N., Fyfe M., Martinell M., Palomino J. C. C., Arjol C. B., <i>PLOS ONE<\/i>, <b>15<\/b>, e0233468 (2020).","DOI":"10.1371\/journal.pone.0233468"},{"key":"55","doi-asserted-by":"crossref","unstructured":"55) Matsuda S., Baba R., Oki H., Morimoto S., Toyofuku M., Igaki S., Kamada Y., Iwasaki S., Matsumiya K., Hibino R., Kamada H., Hirakawa T., Iwatani M., Tsuchida K., Hara R., Ito M., Kimura H., <i>Neuropsychopharmacology<\/i>, <b>44<\/b>, 1505\u20131512 (2019).","DOI":"10.1038\/s41386-018-0300-9"},{"key":"56","doi-asserted-by":"crossref","unstructured":"56) Dong J., Pervaiz W., Tayyab B., Li D., Kang L., Zhang H., Gong H., Ma X., Li J., Agboyibor C., Bi Y., Liu H., <i>Eur. J. Med. Chem.<\/i>, <b>240<\/b>, 114564 (2022).","DOI":"10.1016\/j.ejmech.2022.114564"},{"key":"57","doi-asserted-by":"crossref","unstructured":"57) Schmidt D. M. Z., McCafferty D. G., <i>Biochemistry<\/i>, <b>46<\/b>, 4408\u20134416 (2007).","DOI":"10.1021\/bi0618621"},{"key":"58","doi-asserted-by":"crossref","unstructured":"58) Ji Y.-Y., Lin S.-D., Wang Y.-J., Su M.-B., Zhang W., Gunosewoyo H., Yang F., Li J., Tang J., Zhou Y.-B., Yu L.-F., <i>Eur. J. Med. Chem.<\/i>, <b>141<\/b>, 101\u2013112 (2017).","DOI":"10.1016\/j.ejmech.2017.09.073"},{"key":"59","doi-asserted-by":"crossref","unstructured":"59) Ishikawa Y., Gamo K., Yabuki M., <i>et al.<\/i>, <i>Mol. Cancer Ther.<\/i>, <b>16<\/b>, 273\u2013284 (2017).","DOI":"10.1158\/1535-7163.MCT-16-0471"},{"key":"60","doi-asserted-by":"crossref","unstructured":"60) Yamamoto R., Kawahara M., Ito S., Satoh J., Tatsumi G., Hishizawa M., Suzuki T., Andoh A., <i>Oncotarget<\/i>, <b>9<\/b>, 21007\u201321021 (2018).","DOI":"10.18632\/oncotarget.24774"},{"key":"61","doi-asserted-by":"crossref","unstructured":"61) Hattori Y., Matsumoto S., Morimoto S., Daini M., Toyofuku M., Matsuda S., Baba R., Murakami K., Iwatani M., Oki H., Iwasaki S., Matsumiya K., Tominari Y., Kimura H., Ito M., <i>Eur. J. Med. Chem.<\/i>, <b>239<\/b>, 114522 (2022).","DOI":"10.1016\/j.ejmech.2022.114522"},{"key":"62","doi-asserted-by":"crossref","unstructured":"62) Vianello P., Botrugno O. A., Cappa A., Zuffo R. D., Dessanti P., Mai A., Marrocco B., Mattevi A., Meroni G., Minucci S., Stazi G., Thaler F., Trifir\u00f3 P., Valente S., Villa M., Varasi M., Mercurio C., <i>J. Med. Chem.<\/i>, <b>59<\/b>, 1501\u20131517 (2016).","DOI":"10.1021\/acs.jmedchem.5b01209"},{"key":"63","doi-asserted-by":"crossref","unstructured":"63) Ogasawara D., Itoh Y., Tsumoto H., Kakizawa T., Mino K., Fukuhara K., Nakagawa H., Hasegawa M., Sasaki R., Mizukami T., Miyata N., Suzuki T., <i>Angew. Chem. Int. Ed.<\/i>, <b>52<\/b>, 8620\u20138624 (2013).","DOI":"10.1002\/anie.201303999"},{"key":"64","doi-asserted-by":"crossref","unstructured":"64) Alejo S., Palacios B. E., Venkata P. P., <i>et al.<\/i>, <i>Neuro-oncol.<\/i>, <b>25<\/b>, 1249\u20131261 (2023).","DOI":"10.1093\/neuonc\/noad018"},{"key":"65","doi-asserted-by":"crossref","unstructured":"65) Belkina A. C., Denis G. V., <i>Nat. Rev. Cancer<\/i>, <b>12<\/b>, 465\u2013477 (2012).","DOI":"10.1038\/nrc3256"},{"key":"66","doi-asserted-by":"crossref","unstructured":"66) LeRoy G., Chepelev I., DiMaggio P. A., Blanco M. A., Zee B. M., Zhao K., Garcia B. A., <i>Genome Biol.<\/i>, <b>13<\/b>, R68 (2012).","DOI":"10.1186\/gb-2012-13-8-r68"},{"key":"67","doi-asserted-by":"crossref","unstructured":"67) Umehara T., Nakamura Y., Jang M. K., Nakano K., Tanaka A., Ozato K., Padmanabhan B., Yokoyama S., <i>J. Biol. Chem.<\/i>, <b>285<\/b>, 7610\u20137618 (2010).","DOI":"10.1074\/jbc.M109.062422"},{"key":"68","doi-asserted-by":"crossref","unstructured":"68) Peleg S., Sananbenesi F., Zovoilis A., Burkhardt S., Bahari-Javan S., Agis-Balboa R. C., Cota P., Wittnam J. L., Gogol-Doering A., Opitz L., Salinas-Riester G., Dettenhofer M., Kang H., Farinelli L., Chen W., Fischer A., <i>Science<\/i>, <b>328<\/b>, 753\u2013756 (2010).","DOI":"10.1126\/science.1186088"},{"key":"69","doi-asserted-by":"crossref","unstructured":"69) Matzuk M. M., McKeown M. R., Filippakopoulos P., Li Q., Ma L., Agno J. E., Lemieux M. E., Picaud S., Yu R. N., Qi J., Knapp S., Bradner J. E., <i>Cell<\/i>, <b>150<\/b>, 673\u2013684 (2012).","DOI":"10.1016\/j.cell.2012.06.045"},{"key":"70","doi-asserted-by":"crossref","unstructured":"70) Magistri M., Velmeshev D., Makhmutova M., Patel P., Sartor G. C., Volmar C.-H., Wahlestedt C., Faghihi M. A., <i>Curr. Alzheimer Res.<\/i>, <b>13<\/b>, 985\u2013995 (2016).","DOI":"10.2174\/1567205013666160427101832"},{"key":"71","doi-asserted-by":"crossref","unstructured":"71) Mondragon-Rodriguez S., Perry G., Luna-Munoz J., Acevedo-Aquino M. C., Williams S., <i>Neuropathol. Appl. Neurobiol.<\/i>, <b>40<\/b>, 121\u2013135 (2014).","DOI":"10.1111\/nan.12084"},{"key":"72","doi-asserted-by":"crossref","unstructured":"72) Clinton L. K., Billings L. M., Green K. N., Caccamo A., Ngo J., Oddo S., McGaugh J. L., LaFerla F. M., <i>Neurobiol. Dis.<\/i>, <b>28<\/b>, 76\u201382 (2007).","DOI":"10.1016\/j.nbd.2007.06.013"},{"key":"73","doi-asserted-by":"crossref","unstructured":"73) Filali M., Lalonde R., Theriault P., Julien C., Calon F., Planel E., <i>Behav. Brain Res.<\/i>, <b>234<\/b>, 334\u2013342 (2012).","DOI":"10.1016\/j.bbr.2012.07.004"},{"key":"74","doi-asserted-by":"crossref","unstructured":"74) Picaud S., Wells C., Felletar I., Brotherton D., Martin S., Savitsky P., Diez-Dacal B., Philpott M., Bountra C., Lingard H., Fedorov O., M\u00fcller S., Brennan P. E., Knapp S., Filippakopoulos P., <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>110<\/b>, 19754\u201319759 (2013).","DOI":"10.1073\/pnas.1310658110"},{"key":"75","doi-asserted-by":"crossref","unstructured":"75) Nasreddine Z. S., Phillips N. A., B\u00e9dirian V., Charbonneau S., Whitehead V., Collin I., Cummings J. L., Chertkow H., <i>J. Am. Geriatr. Soc.<\/i>, <b>53<\/b>, 695\u2013699 (2005).","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"76","doi-asserted-by":"crossref","unstructured":"76) Cummings J., Schwartz G. G., Nicholls S. J., Khan A., Halliday C., Toth P. P., Sweeney M., Johansson J. O., Wong N. C. W., Kulikowski E., Kalantar-Zadeh K., Lebioda K., Ginsberg H. N., Winblad B., Zetterberg H., Ray K. K., <i>J. Alzheimers Dis.<\/i>, <b>83<\/b>, 1703\u20131715 (2021).","DOI":"10.3233\/JAD-210570"},{"key":"77","doi-asserted-by":"crossref","unstructured":"77) Wager T. T., Hou X., Verhoest P. R., Villalobos A., <i>ACS Chem. Neurosci.<\/i>, <b>7<\/b>, 767\u2013775 (2016).","DOI":"10.1021\/acschemneuro.6b00029"},{"key":"78","doi-asserted-by":"crossref","unstructured":"78) Zheng Y., Liu A., Wang Z.-J., Cao Q., Wang W., Lin L., Ma K., Zhang F., Wei J., Matas E., Cheng J., Chen G.-J., Wang X., Yan Z., <i>Brain<\/i>, <b>142<\/b>, 787\u2013807 (2019).","DOI":"10.1093\/brain\/awy354"},{"key":"79","doi-asserted-by":"crossref","unstructured":"79) Gri\u00f1\u00e1n-Ferr\u00e9 C., Marsal-Garc\u00eda L., Bellver-Sanchis A., Kondengaden S. M., Turga R. C., V\u00e1zquez S., Pall\u00e0s M., <i>Aging<\/i> (Albany NY), <b>11<\/b>, 11591\u201311608 (2019).","DOI":"10.18632\/aging.102558"},{"key":"80","doi-asserted-by":"crossref","unstructured":"80) Cao Q., Wang W., Williams J. B., Yang F., Wang Z.-J., Yan Z., <i>Sci. Adv.<\/i>, <b>6<\/b>, eabc8096 (2020).","DOI":"10.1126\/sciadv.abc8096"},{"key":"81","doi-asserted-by":"crossref","unstructured":"81) She A., Kurtser I., Reis S. A., Hennig K., Lai J., Lang A., Zhao W.-N., Mazitschek R., Dickerson B. C., Herz J., Haggarty S. J., <i>Cell Chem. Biol.<\/i>, <b>24<\/b>, 892\u2013906 (2017).","DOI":"10.1016\/j.chembiol.2017.06.010"}],"container-title":["Chemical and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/72\/7\/72_c23-00027\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T03:30:38Z","timestamp":1720236638000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/72\/7\/72_c23-00027\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":81,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1248\/cpb.c23-00027","relation":{},"ISSN":["0009-2363","1347-5223"],"issn-type":[{"value":"0009-2363","type":"print"},{"value":"1347-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,1]]},"article-number":"c23-00027"}}