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Sci.<\/i>, <b>74<\/b>, 1062\u20131066 (1985).","DOI":"10.1002\/jps.2600741008"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Talreja P., Kleene N. K., Pickens W. L., Wang T. F., Kasting G. B., <i>AAPS PharmSci<\/i>, <b>3<\/b>, E13 (2001).","DOI":"10.1208\/ps030213"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Wertz P. W., <i>Acta Derm. Venereol.<\/i>, <b>80<\/b> (Suppl. 208), 7\u201311 (2000).","DOI":"10.1080\/000155500750042790"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Benson H. A. E., <i>Curr. Drug Deliv.<\/i>, <b>2<\/b>, 23\u201333 (2005).","DOI":"10.2174\/1567201052772915"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Bouwstra J. A., Honeywell-Nguyen P. L., <i>Adv. Drug Deliv. Rev.<\/i>, <b>54<\/b> (Suppl. 1), S41\u2013S55 (2002).","DOI":"10.1016\/S0169-409X(02)00114-X"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Godin B., Touitou E., <i>Adv. Drug Deliv. Rev.<\/i>, <b>59<\/b>, 1152\u20131161 (2007).","DOI":"10.1016\/j.addr.2007.07.004"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Prausnitz M. R., Bose V. G., Langer R., Weaver J. C., <i>Proc. Natl. Acad. Sci. U.S.A.<\/i>, <b>90<\/b>, 10504\u201310508 (1993).","DOI":"10.1073\/pnas.90.22.10504"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Hirvonen J., Kalia Y. N., Guy R. H., <i>Nat. Biotechnol.<\/i>, <b>14<\/b>, 1710\u20131713 (1996).","DOI":"10.1038\/nbt1296-1710"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Rautio J., Nevalainen T., Taipale H., Veps\u00e4l\u00e4inen J., Gynther J., Pedersen T., J\u00e4rvinen T., <i>Pharm. Res.<\/i>, <b>16<\/b>, 1172\u20131178 (1999).","DOI":"10.1023\/A:1018981010047"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Obata Y., Maruyama Y., Takayama K., <i>Pharm. 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