{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:43:09Z","timestamp":1792212189544,"version":"4.4.0"},"reference-count":23,"publisher":"Pharmaceutical Society of Japan","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Pharm. Bull.","CHEMICAL &amp; PHARMACEUTICAL BULLETIN"],"published-print":{"date-parts":[[2026,10,15]]},"DOI":"10.1248\/cpb.c26-00457","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:11:04Z","timestamp":1792015864000},"page":"772-778","source":"Crossref","is-referenced-by-count":0,"title":["Sequence- and Base-Selective Modification of mRNA within and nearby Premature Termination Codon and Its Effect on the Translation in a Human Cell-Free Translation System"],"prefix":"10.1248","volume":"74","author":[{"given":"Hirotaka","family":"Murase","sequence":"first","affiliation":[{"name":"Faculty of Pharmaceutical Sciences, Sojo University, 4\u201322\u20131 Ikeda, Nishi-ku, Kumamoto 860\u20130082, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeongsu","family":"Lee","sequence":"additional","affiliation":[{"name":"Graduate School of Pharmaceutical Sciences, Nagasaki International University, 2825\u20137 Huis Ten Bosch Machi, Sasebo, Nagasaki 859\u20133298, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Tagawa","sequence":"additional","affiliation":[{"name":"Graduate School of Pharmaceutical Sciences, Nagasaki International University, 2825\u20137 Huis Ten Bosch Machi, Sasebo, Nagasaki 859\u20133298, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1\u20131\u20131 Tsushimanaka, Kita-ku, Okayama 700\u20138530, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Graduate School of Pharmaceutical Sciences, Nagasaki International University, 2825\u20137 Huis Ten Bosch Machi, Sasebo, Nagasaki 859\u20133298, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Stenson P. D., Mort M., Ball E. V., Evans K., Hayden M., Heywood S., Hussain M., Phillips A. D., Cooper D. N., <i>Hum. Genet.<\/i>, <b>136<\/b>, 665\u2013677 (2017).","DOI":"10.1007\/s00439-017-1779-6"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Keeling K. M., Xue X., Gunn G., Bedwell D. M. T., <i>Annu. Rev. Genomics Hum. Genet.<\/i>, <b>15<\/b>, 371\u2013394 (2014).","DOI":"10.1146\/annurev-genom-091212-153527"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Katrekar D., Chen G., Meluzzi D., Ganesh A., Worlikar A., Shih Y. R., Varghese S., Mali P., <i>Nat. Methods<\/i>, <b>16<\/b>, 239\u2013242 (2019).","DOI":"10.1038\/s41592-019-0323-0"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Katrekar D., Yen J., Xiang Y., Saha A., Meluzzi D., Savva Y., Mali P., <i>Nat. Biotechnol.<\/i>, <b>40<\/b>, 938\u2013945 (2022).","DOI":"10.1038\/s41587-021-01171-4"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Karijolich J., Yu Y. T., <i>Nature<\/i>, <b>474<\/b>, 395\u2013398 (2011).","DOI":"10.1038\/nature10165"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Adachi H., Pan Y., He X., Chen J. L., Klein B., Platenburg G., Morais P., Boutz P., Yu Y. T., <i>Mol. Cell<\/i>, <b>83<\/b>, 637\u2013651.e9 (2023).","DOI":"10.1016\/j.molcel.2023.01.009"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Song J., Dong L., Sun H., Luo N., Huang Q., Li K., Shen X., Jiang Z., Lv Z., Peng L., Zhang M., Wang K., Liu K., Hong J., Yi C., <i>Mol. Cell<\/i>, <b>83<\/b>, 139\u2013155.e9 (2022).","DOI":"10.1016\/j.molcel.2022.11.011"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Luo N., Huang Q., Dong L., Liu W., Song J., Sun H., Wu H., Gao Y., Yi C., <i>Nat. Biotechnol.<\/i>, <b>43<\/b>, 114\u2013123 (2025).","DOI":"10.1038\/s41587-024-02165-8"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Dabrowski M., Bukowy-Bieryllo Z., Zietkiewicz E., <i>Mol. Med.<\/i>, <b>24<\/b>, 25 (2018).","DOI":"10.1186\/s10020-018-0024-7"},{"key":"10","unstructured":"10) \u201cPTC Therapeutics Press Release.\u201d: \u2039https:\/\/ir.ptcbio.com\/node\/17651\/pdf\u203a, cited 22 July, 2026."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Murase H., Lee J., Togo N., Taniguchi Y., Sasaki S., <i>Bioorg. Med. Chem.<\/i>, <b>111<\/b>, 117868 (2024).","DOI":"10.1016\/j.bmc.2024.117868"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Onizuka K., Taniguchi Y., Sasaki S., <i>Bioconjug. Chem.<\/i>, <b>20<\/b>, 799\u2013803 (2009).","DOI":"10.1021\/bc900009p"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Onizuka K., Taniguchi Y., Sasaki S., <i>Nucleic Acids Res.<\/i>, <b>38<\/b>, 1760\u20131766 (2010).","DOI":"10.1093\/nar\/gkp930"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Onizuka K., Nishioka T., Li Z., Jitsuzaki D., Taniguchi Y., Sasaki S., <i>Chem. Commun.<\/i>, <b>48<\/b>, 3969\u20133971 (2012).","DOI":"10.1039\/c2cc17621a"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Jitsuzaki D., Onizuka K., Nishimoto A., Oshiro I., Taniguchi Y., Sasaki S., <i>Nucleic Acids Res.<\/i>, <b>42<\/b>, 8808\u20138815 (2014).","DOI":"10.1093\/nar\/gku538"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Oshiro I., Jitsuzaki D., Onizuka K., Nishimoto A., Taniguchi Y., Sasaki S., <i>Chembiochem<\/i>, <b>16<\/b>, 1199\u20131204 (2015).","DOI":"10.1002\/cbic.201500084"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Togo N., Murase H., Lee J., Taniguchi Y., Sasaki S., <i>Chem. Pharm. Bull.<\/i>, <b>70<\/b>, 498\u2013504 (2022).","DOI":"10.1248\/cpb.c22-00288"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Murase H., Eto M., Lee J., Taniguchi Y., Imoto S., Sasaki S., <i>Chem. Commun.<\/i>, <b>60<\/b>, 13440\u201313442 (2024).","DOI":"10.1039\/D4CC04672B"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Murase H., Eto M., Lee J., Taniguchi Y., Imoto S., Sasaki S., <i>Chem. Pharm. Bull.<\/i>, <b>73<\/b>, 1122\u20131125 (2025).","DOI":"10.1248\/cpb.c25-00525"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Takasaki H., Kitazaki K., Hadano Y., Murase H., Lee J., Taniguchi Y., Sasaki S., <i>Chem. Pharm. Bull.<\/i>, <b>73<\/b>, 457\u2013466 (2025).","DOI":"10.1248\/cpb.c25-00068"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Hall M. P., Unch J., Binkowski B. F., Valley M. P., Butler B. L., Wood M. G., Otto P., Zimmerman K., Vidugiris G., Machleidt T., Robers M. B., Benink H. A., Eggers C. T., Slater M. R., Meisenheimer P. L., Klaubert D. H., Fan F., Encell L. P., Wood K. V., <i>ACS Chem. Biol.<\/i>, <b>7<\/b>, 1848\u20131857 (2012).","DOI":"10.1021\/cb3002478"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Susorov D., Echeverria D., Khvorova A., Korostelev A. A., <i>Nucleic Acids Res.<\/i>, <b>52<\/b>, 8687\u20138701 (2024).","DOI":"10.1093\/nar\/gkae624"},{"key":"23","unstructured":"23) \u201cpNL1.1[Nluc] Promoterless vector for measuring the activity of the promoter and enhancer sequences by the NanoLuc\u00ae luciferase assay.\u201d: \u2039https:\/\/www.snapgene.com\/plasmids\/luciferase_vectors\/pNL1.1_Nluc\u203a, cited 1 October, 2024."}],"container-title":["Chemical and Pharmaceutical Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/74\/10\/74_c26-00457\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:22:37Z","timestamp":1792210957000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpb\/74\/10\/74_c26-00457\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1248\/cpb.c26-00457","relation":{},"ISSN":["0009-2363","1347-5223"],"issn-type":[{"value":"0009-2363","type":"print"},{"value":"1347-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"article-number":"c26-00457"}}