{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T03:42:30Z","timestamp":1784691750190,"version":"3.55.0"},"reference-count":73,"publisher":"Pharmaceutical Society of Japan","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["YAKUGAKU ZASSHI"],"published-print":{"date-parts":[[2007,9,1]]},"DOI":"10.1248\/yakushi.127.1419","type":"journal-article","created":{"date-parts":[[2007,9,3]],"date-time":"2007-09-03T05:53:14Z","timestamp":1188798794000},"page":"1419-1430","source":"Crossref","is-referenced-by-count":9,"title":["Development of Drug Delivery Systems for Targeting to Macrophages","\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3092\u6a19\u7684\u3068\u3059\u308b\u30c9\u30e9\u30c3\u30b0\u30c7\u30ea\u30d0\u30ea\u30fc\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9"],"prefix":"10.1248","volume":"127","author":[{"given":"Sumio","family":"CHONO","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, Graduate School of Pharmaceutical Sciences, Hokkaido Pharmaceutical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Allen T. M., Mumbengegwi D. R., Charrois G. J., <i>Clin. Cancer Res.<\/i>, <b>11<\/b>, 3567-3573 (2005).","DOI":"10.1158\/1078-0432.CCR-04-2517"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Chono S., Tauchi Y., Morimoto K., <i>Drug Metab. Pharmacokinet.<\/i>, <b>21<\/b>, 37-44 (2006).","DOI":"10.2133\/dmpk.21.37"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Chono S., Tauchi Y., Morimoto K., <i>Drug Dev. Ind. Pharm.<\/i>, <b>32<\/b>, 125-135 (2006).","DOI":"10.1080\/03639040500390645"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Hitzman C. J., Wattenberg L. W., Wiedmann T. S., <i>J. Pharm. Sci.<\/i>, <b>95<\/b>, 1196-1211 (2006).","DOI":"10.1002\/jps.20607"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Tauchi Y., Takase M., Zushida I., Chono S., Sato J., Ito K., Morimoto K., <i>J. Pharm. Sci.<\/i>, <b>88<\/b>, 709-714 (1999).","DOI":"10.1021\/js980422v"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Hitzman C. J., Elmquist W. F., Wiedmann T. S., <i>J. Pharm. Sci.<\/i>, <b>95<\/b>, 1127-1143 (2006).","DOI":"10.1002\/jps.20590"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7) Hosseinkhani H., Hosseinkhani M., Khademhosseini A., Kobayashi H., Tabata Y., <i>Biomaterials<\/i>, <b>27<\/b>, 5836-5844 (2006).","DOI":"10.1016\/j.biomaterials.2006.08.003"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Kasper F. K., Kushibiki T., Kimura Y., Mikos A. G., Tabata Y., <i>J. Control. Release<\/i>, <b>107<\/b>, 547-561 (2005).","DOI":"10.1016\/j.jconrel.2005.07.005"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Morimoto K., Chono S., Kosai T., Seki T., Tabata Y., <i>J. Pharm. Pharmacol.<\/i>, <b>57<\/b>, 839-844, (2005).","DOI":"10.1211\/0022357056415"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Wang J., Tabata Y., Morimoto K., <i>J. Control. Release<\/i>, <b>113<\/b>, 31-37, (2006).","DOI":"10.1016\/j.jconrel.2006.03.011"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Marttin E., Verhoef J. C., Cullander C., Romeijn S. G., Nagelkerke J. F., Merkus F. W., <i>Pharm. Res.<\/i>, <b>14<\/b>, 631-637 (1997).","DOI":"10.1023\/A:1012109329631"},{"key":"12","unstructured":"12) Seki T., Kanbayashi H., Chono S., Tabata Y., Morimoto K., <i>Int. J. Pharm.<\/i> (in press)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Seki T., Wang A., Yuan D., Saso Y., Hosoya O., Chono S., Morimoto K., <i>J. Control. Release<\/i>, <b>100<\/b>, 181-189 (2004).","DOI":"10.1016\/j.jconrel.2004.08.016"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Seki T., Kanbayashi H., Nagao T., Chono S., Tabata Y., Morimoto K., <i>J. Pharm. Sci.<\/i>, <b>95<\/b>, 1393-1401 (2006).","DOI":"10.1002\/jps.20616"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Yamamoto A., Yamada K., Muramatsu H., Nishinaka A., Okumura S., Okada N., Fujita T., Muranishi S., <i>Int. J. Pharm.<\/i>, <b>282<\/b>, 141-149 (2004).","DOI":"10.1016\/j.ijpharm.2004.06.008"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Chono S., Morimoto K., <i>J. Pharm. Pharmacol.<\/i>, <b>58<\/b>, 1219-1225 (2006).","DOI":"10.1211\/jpp.58.9.0008"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Asai T., Oku N., <i>Methods Enzymol.<\/i>, <b>391<\/b>, 163-176 (2005).","DOI":"10.1016\/S0076-6879(05)91009-4"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Nguyen L.T., Atobe K., Barichello J.M., Ishi- da T., Kiwada H., <i>Biol. Pharm. Bull.<\/i>, <b>30<\/b>, 751-757 (2007).","DOI":"10.1248\/bpb.30.751"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Chono S., Tauchi Y., Morimoto K., <i>J. Drug Target.<\/i>, <b>13<\/b>, 407-414 (2005).","DOI":"10.1080\/10611860500383739"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Chesnoy S., Durand D., Doucet J., Stolz D.B., Huang L., <i>Pharm. Res.<\/i>, <b>18<\/b>, 1480-1484 (2001).","DOI":"10.1023\/A:1012221310136"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Yokoyama M., Opanasopit P., Okano T., Kawano K., Maitani Y., <i>J. Drug Target.<\/i>, <b>12<\/b>, 373-384 (2004).","DOI":"10.1080\/10611860412331285251"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Kushibiki T., Tomoshige R., Iwanaga K., Kakemi M., Tabata Y., <i>J. Biomater. Sci. Polym. Ed.<\/i>, <b>17<\/b>, 645-658 (2006).","DOI":"10.1163\/156856206777346278"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Tauchi Y., Zushida I., Yokota M., Chono S., Sato J., Ito K., Morimoto K., <i>Biol. Pharm. Bull.<\/i>, <b>23<\/b>, 466-471 (2000).","DOI":"10.1248\/bpb.23.466"},{"key":"24","unstructured":"24) Chen J., Corbin I. R., Li H., Cao W., Glickson J. D., Zheng G., <i>J. Am. Chem. Soc.<\/i> (in press)."},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Chono S., Tanino T., Seki T., Morimoto K., <i>J. Drug Target.<\/i>, <b>14<\/b>, 557-566 (2006).","DOI":"10.1080\/10611860600834375"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Oku N., Nojima S., Inoue K., <i>Biochim. Biophys. Acta<\/i>, <b>595<\/b>, 277-290 (1980).","DOI":"10.1016\/0005-2736(80)90090-5"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Adler-Moore J., Proffitt R.T., <i>J. Antimicrob. Chemother.<\/i>, <b>49<\/b>, 21-30 (2002).","DOI":"10.1093\/jac\/49.suppl_1.21"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Harashima H., Houng T. M., Ishida T., Manabe Y., Matsuo H., Kiwada H., <i>Pharm. Res.<\/i>, <b>13<\/b>, 1704-1709 (1996).","DOI":"10.1023\/A:1016401025747"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Chono S., Tanino T., Seki T., Morimoto K., <i>J. Pharm. Pharmacol.<\/i>, <b>59<\/b>, 75-80 (2007).","DOI":"10.1211\/jpp.59.1.0010"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Maruyama K., Takahashi N., Tagawa T., Nagaike K., Iwatsuru M., <i>FEBS Lett.<\/i>, <b>413<\/b>, 177-180 (1997).","DOI":"10.1016\/S0014-5793(97)00905-8"},{"key":"31","unstructured":"31) Kikuchi H., <i>Pharm. Tech. Jpn.<\/i>, <b>19<\/b>, 99-110 (2003)."},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Futaki S., Masui Y., Nakase I., Sugiura Y., Nakamura T., Kogure K., Harashima H., <i>J. Gene Med.<\/i>, <b>7<\/b>, 1450-1458 (2005).","DOI":"10.1002\/jgm.796"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Khalil I.A., Kogure K., Futaki S., Harashima H., <i>J. Biol. Chem.<\/i>, <b>281<\/b>, 3544-3551 (2006).","DOI":"10.1074\/jbc.M503202200"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Li S. D., Huang L., <i>Ann. N. Y. Acad. Sci.<\/i>, 1082, 1-8 (2006).","DOI":"10.1196\/annals.1348.001"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Hodge-Bell K. C., Lee K. M., Renne R. A., Gideon K. M., Harbo S. J., McKinney W. J., <i>Inhal. Toxicol.<\/i>, <b>19<\/b>, 361-376 (2007).","DOI":"10.1080\/08958370601144076"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Roberts R. A., Ganey P. E., Ju C., Kamendulis L. M., Rusyn I., Klaunig J. E., <i>Toxicol. Sci.<\/i>, 2-15 (2007).","DOI":"10.1093\/toxsci\/kfl173"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Ross R., <i>N. Engl. J. Med.<\/i>, <b>340<\/b>, 115-126 (1990).","DOI":"10.1056\/NEJM199901143400207"},{"key":"38","doi-asserted-by":"crossref","unstructured":"39) Chono S., Tauchi Y., Sato J., Ito K., Suzuki M., Morimoto K., <i>Drug Deliv. Syst.<\/i>, <b>14<\/b>, 511-515 (1999).","DOI":"10.2745\/dds.14.511"},{"key":"39","doi-asserted-by":"crossref","unstructured":"40) Tauchi Y., Zushida I., Chono S., Sato J., Ito K., Morimoto K., <i>Biol. Pharm. Bull.<\/i>, <b>24<\/b>, 925-929 (2001).","DOI":"10.1248\/bpb.24.925"},{"key":"40","doi-asserted-by":"crossref","unstructured":"41) Tauchi Y., Chono S., Morimoto K., <i>J. Drug Target.<\/i>, <b>11<\/b>, 163-168 (2003).","DOI":"10.3109\/10611860310001595247"},{"key":"41","doi-asserted-by":"crossref","unstructured":"42) Chono S., Tauchi Y., Deguchi Y., Morimoto K., <i>J. Drug Target.<\/i>, <b>13<\/b>, 267-276 (2005).","DOI":"10.1080\/10611860500159030"},{"key":"42","doi-asserted-by":"crossref","unstructured":"43) Chono S., Tanino T., Seki T., Morimoto K., <i>Drug Metab. Pharmacokinet.<\/i>, <b>22<\/b>, 88-95 (2007).","DOI":"10.2133\/dmpk.22.88"},{"key":"43","doi-asserted-by":"publisher","unstructured":"44) Makheja A. N., Bloom S., Muesing R., Simon T. M., Bailey J. M., <i>Atherosclerosis<\/i>, <b>76<\/b>, 155-161 (1989).","DOI":"10.1016\/0021-9150(89)90099-3"},{"key":"44","doi-asserted-by":"crossref","unstructured":"45) Ross R., <i>N. Engl. J. Med.<\/i>, <b>340<\/b>, 115-126 (1999).","DOI":"10.1056\/NEJM199901143400207"},{"key":"45","doi-asserted-by":"crossref","unstructured":"46) Perry D. G., Wisniowski P., Daugherty G. L., Downing J., Martin W. J., <i>Am. J. Respir. Cell Mol. Biol.<\/i>, <b>17<\/b>, 462-470 (1997).","DOI":"10.1165\/ajrcmb.17.4.2059"},{"key":"46","doi-asserted-by":"publisher","unstructured":"47) Ferrari G., Langen H., Naito M., Pieters J., <i>Cell<\/i>, <b>14<\/b>, 435-447 (1999).","DOI":"10.1016\/S0092-8674(00)80754-0"},{"key":"47","doi-asserted-by":"crossref","unstructured":"48) Harb O. S., Gao L.Y., Abu Kwaik Y., <i>Environ. Microbiol.<\/i>, <b>2<\/b>, 251-265 (2000).","DOI":"10.1046\/j.1462-2920.2000.00112.x"},{"key":"48","doi-asserted-by":"publisher","unstructured":"49) McKinney J. D., Honerzu Bentrup K., Munoz-Elias E. J., Miczak A., Chen B., Chan W. T., Swenson D., Sacchettini J. C., Jacobs Jr. W. R., Russell D. G., <i>Nature<\/i>, <b>406<\/b>, 735-738 (2000).","DOI":"10.1038\/35021074"},{"key":"49","doi-asserted-by":"crossref","unstructured":"50) Vazquez-Boland J. A., Kuhn M., Berche P., Chakraborty T., Dominguez-Bernal G., Goebel W., Gonzalez-Zorn B., Wehland J., Kreft J., <i>Clin. Microbiol. Rev.<\/i>, <b>14<\/b>, 584-640 (2001).","DOI":"10.1128\/CMR.14.3.584-640.2001"},{"key":"50","doi-asserted-by":"crossref","unstructured":"51) Greub G., Raoult D., <i>Clin. Microbiol. Rev.<\/i>, <b>17<\/b>, 413-433 (2004).","DOI":"10.1128\/CMR.17.2.413-433.2004"},{"key":"51","doi-asserted-by":"crossref","unstructured":"52) Yee D., Valiquette C., Pelletier M., Parisien I., Rocher I., Menzies D., <i>Am. J. Respir. Crit. Care Med.<\/i>, <b>167<\/b>, 1472-1477 (2003).","DOI":"10.1164\/rccm.200206-626OC"},{"key":"52","doi-asserted-by":"crossref","unstructured":"53) Fehrenbach H., <i>Respir. Res<\/i>, <b>2<\/b>, 33-46 (2001).","DOI":"10.1186\/rr36"},{"key":"53","doi-asserted-by":"crossref","unstructured":"54) Poelma D. L., Zimmermann L. J., Scholten H. H., Lachmann B., van Iwaarden J. F., <i>Am. J. Physiol. Lung Cell Mol. Physiol.<\/i>, <b>283<\/b>, 648-654 (2002).","DOI":"10.1152\/ajplung.00478.2001"},{"key":"54","doi-asserted-by":"crossref","unstructured":"55) Harashima H., Sakata K., Funato K., Kiwada H., <i>Pharm. Res.<\/i>, <b>11<\/b>, 402-406 (1994).","DOI":"10.1023\/A:1018965121222"},{"key":"55","doi-asserted-by":"crossref","unstructured":"56) Lane K. B., Egan B., Vick S., Abdolrasulnia R., Shepherd V. L., <i>J. Leukoc. Biol.<\/i>, <b>64<\/b>, 345-350 (1998).","DOI":"10.1002\/jlb.64.3.345"},{"key":"56","doi-asserted-by":"crossref","unstructured":"57) Chroneos Z. C., Abdolrasulnia R., Whitsett J. A., Rice W. R., Shepherd V. L., <i>J. Biol. Chem.<\/i>, <b>271<\/b>, 16375-16383 (1996).","DOI":"10.1074\/jbc.271.27.16375"},{"key":"57","doi-asserted-by":"crossref","unstructured":"58) Gronlund J., Vitved L., Lausen M., Skjodt K., Holmskov U., <i>J. Immunol.<\/i>, <b>165<\/b>, 6406-6415 (2000).","DOI":"10.4049\/jimmunol.165.11.6406"},{"key":"58","first-page":"1073","volume":"37","year":"1993","unstructured":"59) Forrest A., Nix D. E., Ballow C. H., Goss T. F., Birmingham M. C., Schentag J. J., <i>Chemotherapy<\/i>, <b>37<\/b>, 1073-1081 (1993).","journal-title":"Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0009-3157","issn-type":"print"},{"key":"59","doi-asserted-by":"publisher","unstructured":"60) Preston S. L., Drusano G. L., Berman A. L., Fowler C. L., Chow A. T., Dornseif B., Reichl V., Natarajan J., Corrado M., <i>JAMA<\/i>, <b>279<\/b>, 125-129 (1998).","DOI":"10.1001\/jama.279.2.125"},{"key":"60","doi-asserted-by":"crossref","unstructured":"61) Blaser J., Stone B. B., Groner M. C., Zinner S. H., <i>Antimicrob. Agents Chemother.<\/i>, <b>31<\/b>, 1054-1060 (1987).","DOI":"10.1128\/AAC.31.7.1054"},{"key":"61","doi-asserted-by":"crossref","unstructured":"62) Craig W. A., <i>Diagn. Microbiol. Infect. Dis.<\/i>, <b>22<\/b>, 89-96 (1995).","DOI":"10.1016\/0732-8893(95)00053-D"},{"key":"62","doi-asserted-by":"crossref","unstructured":"63) Hyatt J. M., McKinnon P. S., Zimmer G. S., Schentag J. J, <i>Clin. Pharmacokinet.<\/i>, <b>28<\/b>, 143-160 (1995).","DOI":"10.2165\/00003088-199528020-00005"},{"key":"63","doi-asserted-by":"crossref","unstructured":"64) Moore R. D., Lietman P. S., Smith C. R., <i>J. Infect. Dis.<\/i>, <b>155<\/b>, 93-99 (2005).","DOI":"10.1093\/infdis\/155.1.93"},{"key":"64","doi-asserted-by":"crossref","unstructured":"65) Toutain P. L., del Castillo J. R., Bousquet-Melou A., <i>Res. Vet. Sci.<\/i>, <b>73<\/b>, 105-114 (2002).","DOI":"10.1016\/S0034-5288(02)00039-5"},{"key":"65","doi-asserted-by":"crossref","unstructured":"66) Onodera Y., Tanaka M., Sato K., <i>J. Antimicrob. Chemother.<\/i>, <b>47<\/b>, 447-450 (2001).","DOI":"10.1093\/jac\/47.4.447"},{"key":"66","doi-asserted-by":"crossref","unstructured":"67) Tomioka H., Sato K., Kajitani H., Akaki T., Shishido S., <i>Antimicrob. Agents Chemother.<\/i>, <b>44<\/b>, 283-286 (2000).","DOI":"10.1128\/AAC.44.2.283-286.2000"},{"key":"67","doi-asserted-by":"crossref","unstructured":"68) Harnett S. J., Fraise A. P., Andrews J. M., Jevons G., Brenwald N. P., Wise R., <i>J. Antimicrob. Chemother.<\/i>, <b>53<\/b>, 783-792 (2004).","DOI":"10.1093\/jac\/dkh180"},{"key":"68","doi-asserted-by":"crossref","unstructured":"69) Safdar A., Armstrong D., <i>J. Clin. Microbiol.<\/i>, <b>41<\/b>, 483-485 (2003).","DOI":"10.1128\/JCM.41.1.483-485.2003"},{"key":"69","doi-asserted-by":"crossref","unstructured":"70) Dubois J., St-Pierre C., <i>J. Antimicrob. Chemother.<\/i>, <b>45<\/b>, 41-46 (2000).","DOI":"10.1093\/jac\/45.suppl_3.41"},{"key":"70","doi-asserted-by":"crossref","unstructured":"71) Ikaheimo I., Syrjala H., Karhukorpi J., Schildt R., Koskela M., <i>J. Antimicrob. Chemother.<\/i>, <b>46<\/b>, 287-290 (2000).","DOI":"10.1093\/jac\/46.2.287"},{"key":"71","doi-asserted-by":"crossref","unstructured":"72) Drlica K., <i>J. Antimicrob. Chemother.<\/i>, <b>52<\/b>, 11-17 (2003).","DOI":"10.1093\/jac\/dkg269"},{"key":"72","doi-asserted-by":"crossref","unstructured":"73) Rodriguez J. C., Cebrian L., Lopez M., Ruiz M., Jimenez I., Royo G., <i>J. Antimicrob. Chemother.<\/i>, <b>53<\/b>, 441-444 (2004).","DOI":"10.1093\/jac\/dkh119"},{"key":"73","doi-asserted-by":"crossref","unstructured":"74) Rodriguez J. C., Cebrian L., Lopez M., Ruiz M., Royo G., <i>Int. J. Antimicrob. Agents<\/i>, <b>25<\/b>, 221-225 (2005).","DOI":"10.1016\/j.ijantimicag.2004.09.018"}],"container-title":["YAKUGAKU ZASSHI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/127\/9\/127_9_1419\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T19:50:03Z","timestamp":1556826603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/127\/9\/127_9_1419\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,1]]},"references-count":73,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1248\/yakushi.127.1419","relation":{},"ISSN":["0031-6903","1347-5231"],"issn-type":[{"value":"0031-6903","type":"print"},{"value":"1347-5231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,1]]}}}