{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T13:30:01Z","timestamp":1696685401128},"reference-count":8,"publisher":"Pharmaceutical Society of Japan","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["YAKUGAKU ZASSHI"],"published-print":{"date-parts":[[2010,4,1]]},"DOI":"10.1248\/yakushi.130.521","type":"journal-article","created":{"date-parts":[[2010,4,2]],"date-time":"2010-04-02T01:57:53Z","timestamp":1270173473000},"page":"521-526","source":"Crossref","is-referenced-by-count":6,"title":["Development of Anti-Alzheimer's Disease Drug Based on Beta-Amyloid Hypothesis"],"prefix":"10.1248","volume":"130","author":[{"given":"Hachiro","family":"SUGIMOTO","sequence":"first","affiliation":[{"name":"Department of Neuroloscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"163","reference":[{"key":"1","first-page":"1403","volume":"308","year":"1976","unstructured":"1) Davies P., Maloney A. J. F., <i>Lancet<\/i>, <b>308<\/b>, 1403 (1976).","journal-title":"The Lancet","ISSN":"http:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"2","first-page":"189","volume":"309","year":"1977","unstructured":"2) Perry E. K., Perry R. H., Blessed G., Tomlinson B. E., <i>Lancet<\/i>, <b>309<\/b>, 189 (1977).","journal-title":"The Lancet","ISSN":"http:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Sugimoto H., Iimura Y., Yamanishi Y., Yamatsu K., <i>J. Med. Chem.<\/i>, <b>38<\/b>, 4821-4829 (1995).","DOI":"10.1021\/jm00024a009"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Selkoe D. J., <i>Pysiol. Rev.<\/i>, <b>81<\/b>, 741-766 (2001).","DOI":"10.1152\/physrev.2001.81.2.741"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5) Kukar T. L., Ladd T. B., Bann M. A., Fraering P. C., Narlawar R., Maharvi G. M., Healy B., Chapman R., Welzel A. T., Price R. W., Moore B., Rangachari V., Cusack B., Eriksen J., Jansen-West K., Verbeeck C., Yager D., Eckman C., Ye W., Sagi S., Cottrell B. A., Torpey J., Rosenberry T. L., Fauq A., Wolfe M. S., Schmidt B., Walsh D. M., Koo E. H., Golde T. E., <i>Nature<\/i>, <b>453<\/b>, 925-929 (2008).","DOI":"10.1038\/nature07055"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6) Aisen P. S., Saumier D., Briand R., Laurin J., Gervais F., Tremblay P., Garceau D., <i>Neurology<\/i>, <b>67<\/b>, 1757-1763 (2006).","DOI":"10.1212\/01.wnl.0000244346.08950.64"},{"key":"7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/22124","volume":"400","year":"1999","unstructured":"7) Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., Seubert P., <i>Nature<\/i>, <b>400<\/b>, 173-175 (1999).","journal-title":"Nature Cell Biology","ISSN":"http:\/\/id.crossref.org\/issn\/0028-0836","issn-type":"print"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Atamna H., Nguyen A., Schultz C., Boyle K., Newberry J., Kato H., Ames B., <i>FASEB J.<\/i>, <b>22<\/b>, 703-712 (2008).","DOI":"10.1096\/fj.07-9610com"}],"container-title":["YAKUGAKU ZASSHI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/130\/4\/130_4_521\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T05:35:43Z","timestamp":1535780143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/130\/4\/130_4_521\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,1]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1248\/yakushi.130.521","relation":{},"ISSN":["0031-6903","1347-5231"],"issn-type":[{"value":"0031-6903","type":"print"},{"value":"1347-5231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,1]]}}}