{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T08:10:01Z","timestamp":1748679001855,"version":"3.41.0"},"reference-count":18,"publisher":"Pharmaceutical Society of Japan","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["YAKUGAKU ZASSHI"],"published-print":{"date-parts":[[2015,11,1]]},"DOI":"10.1248\/yakushi.15-00200","type":"journal-article","created":{"date-parts":[[2015,10,31]],"date-time":"2015-10-31T22:13:43Z","timestamp":1446329623000},"page":"1273-1279","source":"Crossref","is-referenced-by-count":2,"title":["<i>In Vitro<\/i> and <i>in Vivo<\/i> Assessments of Drug-induced Hepatotoxicity and Drug Metabolism in Humans","\u30d2\u30c8\u306b\u304a\u3051\u308b\u533b\u85ac\u54c1\u306e\u809d\u6bd2\u6027\u53ca\u3073\u4ee3\u8b1d\u7269\u306e <i>in vitro<\/i>, <i>in vivo<\/i> \u4e88\u6e2c\u8a55\u4fa1\u7cfb\u306e\u69cb\u7bc9\u306b\u95a2\u3059\u308b\u7814\u7a76"],"prefix":"10.1248","volume":"135","author":[{"given":"Seigo","family":"Sanoh","sequence":"first","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences, Hiroshima Univeristy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"163","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Kola I., Landis J., Nat. Rev. Drug Discov.<\/i>, 3<\/b>, 711-716 (2004).","DOI":"10.1038\/nrd1470"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Smith D. A., Obach R. S., Chem. Res. Toxicol.<\/i>, 22<\/b>, 267-279 (2009).","DOI":"10.1021\/tx800415j"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Chen M., Vijay V., Shi Q., Liu Z., Fang H., Tong W., Drug Discov. Today<\/i>, 16<\/b>, 697-703 (2011).","DOI":"10.1016\/j.drudis.2011.05.007"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Dalvie D., Obach R. S., Kang P., Prakash C., Loi C. M., Hurst S., Nedderman A., Goulet L., Smith E., Bu H. Z., Smith D. A., Chem. Res. Toxicol.<\/i>, 22<\/b>, 357-368 (2009).","DOI":"10.1021\/tx8004357"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Gómez-Lechón M. J., Tolosa L., Conde I., Donato M. T., Expert Opin. Drug Metab. Toxicol.<\/i>, 10<\/b>, 1553-1568 (2014).","DOI":"10.1517\/17425255.2014.967680"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Sanoh S., Santoh M., Takagi M., Kanayama T., Sugihara K., Kotake Y., Ejiri Y., Horie T., Kitamura S., Ohta S., Toxicol. in Vitro<\/i>, 28<\/b>, 1176-1182 (2014).","DOI":"10.1016\/j.tiv.2014.05.007"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) James L. P., Mayeux P. R., Hinson J. A., Drug Metab. Dispos.<\/i>, 31<\/b>, 1499-1506 (2003).","DOI":"10.1124\/dmd.31.12.1499"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Tateno C., Yoshizane Y., Saito N., Kataoka M., Utoh R., Yamasaki C., Tachibana A., Soeno Y., Asahina K., Hino H., Asahara T., Yokoi T., Furukawa T., Yoshizato K., Am. J. Pathol.<\/i>, 165<\/b>, 901-912 (2004).","DOI":"10.1016\/S0002-9440(10)63352-4"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Shirley M. A., Guan X., Kaiser D. G., Halstead G. W., Baillie T. A., J. Pharmacol. Exp. Ther.<\/i>, 269<\/b>, 1166-1175 (1994).","DOI":"10.1016\/S0022-3565(25)38854-3"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kepp D. R., Sidelmann U. G., Tjørnelund J., Hansen S. H., J. Chromatogr. B Biomed. Sci. Appl.<\/i>, 696<\/b>, 235-241 (1997).","DOI":"10.1016\/S0378-4347(97)00239-9"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Sanoh S., Horiguchi A., Sugihara K., Kotake Y., Tayama Y., Uramaru N., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S., Drug Metab. Dispos.<\/i>, 40<\/b>, 2267-2272 (2012).","DOI":"10.1124\/dmd.112.047555"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Akabane T., Tanaka K., Irie M., Terashita S., Teramura T., Xenobiotica<\/i>, 41<\/b>, 372-384 (2011).","DOI":"10.3109\/00498254.2010.549970"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Hutzler J. M., Obach R. S., Dalvie D., Zientek M. A., Expert Opin. Drug Metab. Toxicol.<\/i>, 9<\/b>, 153-168 (2013).","DOI":"10.1517\/17425255.2013.738668"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Garattini E., Terao M., Expert Opin. Drug Metab. Toxicol.<\/i>, 8<\/b>, 487-503 (2012).","DOI":"10.1517\/17425255.2012.663352"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Sanoh S., Tayama Y., Sugihara K., Kitamura S., Ohta S., Drug Metab. Pharmacokinet.<\/i>, 30<\/b>, 52-63 (2015).","DOI":"10.1016\/j.dmpk.2014.10.009"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Sanoh S., Nozaki K., Murai H., Terashita S., Teramura T., Ohta S., Drug Metab. Dispos.<\/i>, 40<\/b>, 76-82 (2012).","DOI":"10.1124\/dmd.111.041954"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Sanoh S., Horiguchi A., Sugihara K., Kotake Y., Tayama Y., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S., Drug Metab. Dispos.<\/i>, 40<\/b>, 322-328 (2012).","DOI":"10.1124\/dmd.111.040923"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Sanoh S., Ohta S., Biopharm. Drug Dispos.<\/i>, 35<\/b>, 71-86 (2014).","DOI":"10.1002\/bdd.1864"}],"container-title":["YAKUGAKU ZASSHI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/135\/11\/135_15-00200\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T07:49:51Z","timestamp":1748677791000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yakushi\/135\/11\/135_15-00200\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,1]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1248\/yakushi.15-00200","relation":{},"ISSN":["0031-6903","1347-5231"],"issn-type":[{"type":"print","value":"0031-6903"},{"type":"electronic","value":"1347-5231"}],"subject":[],"published":{"date-parts":[[2015,11,1]]}}}