{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T15:27:54Z","timestamp":1787326074951,"version":"build-2736575974"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1249\/mss.0b013e3181ef5bf8","type":"journal-article","created":{"date-parts":[[2010,7,14]],"date-time":"2010-07-14T06:41:33Z","timestamp":1279089693000},"page":"432-442","source":"Crossref","is-referenced-by-count":82,"title":["What Is the Effect of Physical Activity on the Knee Joint? A Systematic Review"],"prefix":"10.1249","volume":"43","author":[{"given":"DONNA M.","family":"URQUHART","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JEPHTAH F. L.","family":"TOBING","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FAHAD S.","family":"HANNA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PATRICIA","family":"BERRY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANITA E.","family":"WLUKA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHANGHAI","family":"DING","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FLAVIA M.","family":"CICUTTINI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20210227","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/oxfordjournals.aje.a117618","article-title":"Reproducibility and validity of an epidemiologic questionnaire to assess past year physical activity in adolescents.","volume":"42","author":"Aaron","year":"1995","journal-title":"Am J Epidemiol"},{"key":"R2-8-20210227","first-page":"1218","article-title":"Factors associated with radiographic osteoarthritis: results from the population study 70-year-old people in Goteborg.","volume":"18","author":"Bagge","year":"1991","journal-title":"J Rheumatol"},{"key":"R3-8-20210227","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.amepre.2008.03.032","article-title":"Long distance running and knee osteoarthritis: a prospective study.","volume":"35","author":"Chakravarty","year":"2008","journal-title":"Am J Prev Med"},{"key":"R4-8-20210227","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/rheumatology\/keg073","article-title":"Factors affecting knee cartilage volume in healthy men.","volume":"42","author":"Cicuttini","year":"2003","journal-title":"Rheumatology (Oxford)"},{"key":"R5-8-20210227","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1002\/art.10840","article-title":"Comparison of tibial cartilage volume and radiologic grade of the tibiofemoral joint.","volume":"48","author":"Cicuttini","year":"2003","journal-title":"Arthritis Rheum"},{"key":"R6-8-20210227","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1002\/1529-0131(200005)43:5<995::AID-ANR6>3.0.CO;2-1","article-title":"Risk factors for the incidence and progression of radiographic knee osteoarthritis.","volume":"43","author":"Cooper","year":"2000","journal-title":"Arthritis Rheum"},{"key":"R7-8-20210227","doi-asserted-by":"crossref","first-page":"187","DOI":"10.5694\/j.1326-5377.1997.tb140072.x","article-title":"Osteoarthritis of the knee in retired, elite Australian Rules footballers.","volume":"166","author":"Deacon","year":"1997","journal-title":"Med J Aust"},{"key":"R8-8-20210227","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1053\/joca.2001.0480","article-title":"Functional adaptation of human joints to mechanical stimuli.","volume":"10","author":"Eckstein","year":"2002","journal-title":"Osteoarthritis Cartilage"},{"key":"R9-8-20210227","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/ard.2004.022400","article-title":"In vivo cartilage deformation after different types of activity and its dependence on physical training status.","volume":"64","author":"Eckstein","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"R10-8-20210227","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.annrmp.2008.01.003","article-title":"Knee osteoarthritis in 50 former top-level soccer players: a comparative study in French.","volume":"51","author":"Elleuch","year":"2008","journal-title":"Ann Readapt Med Phys"},{"key":"R11-8-20210227","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/art.22464","article-title":"Effect of recreational physical activities on the development of knee osteoarthritis in older adults of different weights: the Framingham Study.","volume":"57","author":"Felson","year":"2007","journal-title":"Arthritis Rheum"},{"key":"R12-8-20210227","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1002\/art.1780400420","article-title":"Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study.","volume":"40","author":"Felson","year":"1997","journal-title":"Arthritis Rheum"},{"issue":"3","key":"R13-8-20210227","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1249\/mss.0b013e31802d97c6","article-title":"Physical activity and knee structural change: a longitudinal study using MRI.","volume":"39","author":"Foley","year":"2007","journal-title":"Med Sci Sports Exerc"},{"key":"R14-8-20210227","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1136\/ard.2004.029355","article-title":"Factors influencing longitudinal change in knee cartilage volume measured from magnetic resonance imaging in healthy men.","volume":"64","author":"Hanna","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"R15-8-20210227","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1097\/gme.0b013e31802f316b","article-title":"The cross-sectional relationship between fortnightly exercise and knee cartilage properties in healthy adult women in midlife.","volume":"14","author":"Hanna","year":"2007","journal-title":"Menopause"},{"key":"R16-8-20210227","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/art.22535","article-title":"Factors affecting patella cartilage and bone in middle-aged women.","volume":"57","author":"Hanna","year":"2007","journal-title":"Arthritis Rheum"},{"key":"R17-8-20210227","first-page":"704","article-title":"Habitual physical activity is not associated with knee osteoarthritis: the Framingham Study.","volume":"20","author":"Hannan","year":"1993","journal-title":"J Rheumatol"},{"key":"R18-8-20210227","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/1529-0131(199901)42:1<17::AID-ANR2>3.0.CO;2-E","article-title":"Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study.","volume":"42","author":"Hart","year":"1999","journal-title":"Arthritis Rheum"},{"key":"R19-8-20210227","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/1047-2797(94)90100-7","article-title":"Physical activity as a risk factor for osteoarthritis of the knee.","volume":"4","author":"Imeokparia","year":"1994","journal-title":"Ann Epidemiol"},{"key":"R20-8-20210227","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1203\/01.PDR.0000072781.93856.E6","article-title":"Knee articular cartilage development in children: a longitudinal study of the effect of sex, growth, body composition, and physical activity.","volume":"54","author":"Jones","year":"2003","journal-title":"Pediatr Res"},{"key":"R21-8-20210227","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/art.24255","article-title":"Long-term effects of chondroitins 4 and 6 sulfate on knee osteoarthritis: the study on osteoarthritis progression prevention, a two-year, randomized, double-blind, placebo-controlled trial.","volume":"60","author":"Kahan","year":"2009","journal-title":"Arthritis Rheum"},{"key":"R22-8-20210227","doi-asserted-by":"crossref","first-page":"925","DOI":"10.3109\/17453678008990896","article-title":"Osteoarthritis of the hip and knee joint in retired football players.","volume":"51","author":"Klunder","year":"1980","journal-title":"Acta Orthop Scand"},{"key":"R23-8-20210227","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1177\/036354659001800408","article-title":"Long distance running and osteoarthrosis.","volume":"18","author":"Konradsen","year":"1990","journal-title":"Am J Sports Med"},{"key":"R24-8-20210227","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s002560000296","article-title":"MR imaging of the knee in marathon runners before and after competition.","volume":"30","author":"Krampla","year":"2001","journal-title":"Skeletal Radiol"},{"key":"R25-8-20210227","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/art.1780380413","article-title":"Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters.","volume":"38","author":"Kujala","year":"1995","journal-title":"Arthritis Rheum"},{"key":"R26-8-20210227","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0002-9343(90)90422-A","article-title":"Running, osteoarthritis, and bone density: initial 2-year longitudinal study.","volume":"88","author":"Lane","year":"1990","journal-title":"Am J Med"},{"key":"R27-8-20210227","first-page":"461","article-title":"The risk of osteoarthritis with running and aging: a 5-year longitudinal study.","volume":"20","author":"Lane","year":"1993","journal-title":"J Rheumatol"},{"key":"R28-8-20210227","first-page":"334","article-title":"The relationship of running to osteoarthritis of the knee and hip and bone mineral density of the lumbar spine: a 9 year longitudinal study.","volume":"25","author":"Lane","year":"1998","journal-title":"J Rheumatol"},{"key":"R29-8-20210227","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/aje\/152.9.855","article-title":"Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities.","volume":"152","author":"Lau","year":"2000","journal-title":"Am J Epidemiol"},{"key":"R30-8-20210227","first-page":"2520","article-title":"Influence of work on the development of osteoarthritis of the hip: a systematic review.","volume":"28","author":"Lievense","year":"2001","journal-title":"J Rheumatol"},{"key":"R32-8-20210227","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0002-9343(98)00413-6","article-title":"Level of physical activity and the risk of radiographic and symptomatic knee osteoarthritis in the elderly: the Framingham study.","volume":"106","author":"McAlindon","year":"1999","journal-title":"Am J Med"},{"key":"R33-8-20210227","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/BF02207964","article-title":"Osteophytosis of the knee: association with changes in weight-bearing exercise.","volume":"11","author":"Michel","year":"1992","journal-title":"Clin Rheumatol"},{"key":"R34-8-20210227","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/art.22245","article-title":"Effects of strength training on the incidence and progression of knee osteoarthritis.","volume":"55","author":"Mikesky","year":"2006","journal-title":"Arthritis Rheum"},{"key":"R35-8-20210227","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/ard.36.4.327","article-title":"The knees and ankles in sport and veteran military parachutists.","volume":"36","author":"Murray-Leslie","year":"1977","journal-title":"Ann Rheum Dis"},{"key":"R36-8-20210227","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1002\/art.22990","article-title":"Effect of physical activity on articular knee joint structures in community-based adults.","volume":"57","author":"Racunica","year":"2007","journal-title":"Arthritis Rheum"},{"key":"R37-8-20210227","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0140-6736(00)03610-2","article-title":"Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial.","volume":"357","author":"Reginster","year":"2001","journal-title":"Lancet"},{"key":"R38-8-20210227","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1002\/art.21415","article-title":"Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritis.","volume":"52","author":"Roos","year":"2005","journal-title":"Arthritis Rheum"},{"key":"R39-8-20210227","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1002\/art.23973","article-title":"The effect of glucosamine and\/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine\/chondroitin arthritis intervention trial.","volume":"58","author":"Sawitzke","year":"2008","journal-title":"Arthritis Rheum"},{"key":"R40-8-20210227","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/art.1780390616","article-title":"Risk of osteoarthritis associated with long-term weight-bearing sports: a radiologic survey of the hips and knees in female ex-athletes and population controls.","volume":"39","author":"Spector","year":"1996","journal-title":"Arthritis Rheum"},{"key":"R41-8-20210227","first-page":"1835","article-title":"The relationship between prospectively assessed body weight and physical activity and prevalence of radiological knee osteoarthritis in postmenopausal women.","volume":"33","author":"Szoeke","year":"2006","journal-title":"J Rheumatol"},{"key":"R42-8-20210227","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.bone.2006.05.016","article-title":"Factors affecting the prevalence of osteoarthritis in healthy middle-aged women: data from the longitudinal Melbourne Women's Midlife Health Project.","volume":"39","author":"Szoeke","year":"2006","journal-title":"Bone"},{"key":"R44-8-20210227","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.joca.2006.11.006","article-title":"Osteophytes: relevance and biology.","volume":"15","author":"van der Kraan","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"R45-8-20210227","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.jbspin.2006.03.001","article-title":"Osteoarthritis of the knee and hip and activity: a systematic international review and synthesis (OASIS).","volume":"73","author":"Vignon","year":"2006","journal-title":"Joint Bone Spine"},{"key":"R46-8-20210227","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.joca.2006.05.010","article-title":"Factors affecting tibial plateau expansion in healthy women over 2.5 years: a longitudinal study.","volume":"14","author":"Wang","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"R47-8-20210227","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1093\/rheumatology\/ken244","article-title":"The determinants of change in patella cartilage volume-a cohort study of healthy middle-aged women.","volume":"47","author":"Wijayaratne","year":"2008","journal-title":"Rheumatology (Oxford)"}],"container-title":["Medicine &amp; Science in Sports &amp; Exercise"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005768-201103000-00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:26:26Z","timestamp":1787322386000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005768-201103000-00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1249\/mss.0b013e3181ef5bf8","relation":{},"ISSN":["0195-9131"],"issn-type":[{"value":"0195-9131","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}