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Huxley R, Barzi F, Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: Meta-analysis of 37 prospective cohort studies. BMJ 2006; 332: 73-78.","DOI":"10.1136\/bmj.38678.389583.7C"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, et al; Japan CDM group. Importance of lipid levels in elderly diabetic individuals: Baseline characteristics and 1-year survey of cardiovascular events. Circ J 2008; 72: 218-225.","DOI":"10.1253\/circj.72.218"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Haffner SM, Lehto S, R&ouml;nnemaa T, Py&ouml;r&auml;l&auml; K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339: 229-234.","DOI":"10.1056\/NEJM199807233390404"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Temelkova-Kurktschiev TS, Koehler C, Henkel E, Leonhardt W, Fuecker K, Hanefeld M. Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level. Diabetes Care 2000; 23: 1830-1834.","DOI":"10.2337\/diacare.23.12.1830"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Azuma K, Kawamori R, Toyofuku Y, Kitahara Y, Sato F, Shimizu T, et al. Repetitive fluctuations in blood glucose enhance monocyte adhesion to the endothelium of rat thoracic aorta. Arterioscler Thromb Vasc Biol 2006; 26: 2275-2780.","DOI":"10.1161\/01.ATV.0000239488.05069.03"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Mita T, Otsuka A, Azuma K, Uchida T, Ogihara T, Fujitani Y, et al. Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice. Biochem Biophys Res Commun 2007; 358: 679-685.","DOI":"10.1016\/j.bbrc.2007.04.118"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. 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