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Kim YH, Lee SC, Her AY, Kim HJ, Choi JO, Shin DH, et al. Preoperative left atrial volume index is a predictor of successful sinus rhythm restoration and maintenance after the maze operation. J Thorac Cardiovasc Surg 2007; 134: 448&ndash;453.","DOI":"10.1016\/j.jtcvs.2007.02.031"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Saunders R, Siddiqui S, Kaur D, Doe C, Sutcliffe A, Hollins F, et al. Fibrocyte localization to the airway smooth muscle is a feature of asthma. J Allergy Clin Immunol 2009; 123: 376&ndash;384.","DOI":"10.1016\/j.jaci.2008.10.048"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Ko WC, Hong CY, Hou SM, Lin CH, Ong ET, Lee CF, et al. Elevated expression of connective tissue growth factor in human atrial fibrillation and angiotensin II-treated cardiomyocytes. Circ J 2011; 75: 1592&ndash;1600.","DOI":"10.1253\/circj.CJ-10-0892"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. 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