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Libby P, Plutzky J. Inflammation in diabetes mellitus: Role of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma agonists. <i>Am J Cardiol<\/i> 2007; 99: 27B\u201340B.","DOI":"10.1016\/j.amjcard.2006.11.004"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Choi KY, Kim DB, Kim MJ, Kwon BJ, Chang SY, Jang SW, et al. Higher plasma thrombospondin-1 levels in patients with coronary artery disease and diabetes mellitus. <i>Korean Circ J<\/i> 2012; 42: 100\u2013106.","DOI":"10.4070\/kcj.2012.42.2.100"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Iwasaki M, Otake H, Shinke T, Nakagawa M, Hariki H, Osue T, et al. Vascular responses in patients with and without diabetes mellitus after everolimus-eluting stent implantation: Optical coherence tomography study. <i>Circ J<\/i> 2014; 78: 2188\u20132196.","DOI":"10.1253\/circj.CJ-13-1540"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Hong SJ, Kim MH, Ahn TH, Ahn YK, Bae JH, Shim WJ, et al. Multiple predictors of coronary restenosis after drug-eluting stent implantation in patients with diabetes. <i>Heart<\/i> 2006; 92: 1119\u20131124.","DOI":"10.1136\/hrt.2005.075960"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Hong SJ, Kim MH, Cha KS, Park HS, Chae SC, Hur SH, et al. Comparison of three-year clinical outcomes between sirolimus-versus paclitaxel-eluting stents in diabetic patients: Prospective randomized multicenter trial. <i>Catheter Cardiovasc Interv<\/i> 2010; 76: 924\u2013933.","DOI":"10.1002\/ccd.22369"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Meigs JB, Hu FB, Rifai N, Manson JE. Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. <i>JAMA<\/i> 2004; 291: 1978\u20131986.","DOI":"10.1001\/jama.291.16.1978"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Akcakoyun M, Kargin R, Tanalp AC, Pala S, Ozveren O, Akcay M, et al. Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events and restenosis in patients undergoing coronary stent implantation: A prospective study. <i>Coron Artery Dis<\/i> 2008; 19: 337\u2013343.","DOI":"10.1097\/MCA.0b013e328301ba8e"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Gilbert RE. Endothelial loss and repair in the vascular complications of diabetes: Pathogenetic mechanisms and therapeutic implications. <i>Circ J<\/i> 2013; 77: 849\u2013856.","DOI":"10.1253\/circj.CJ-13-0236"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Hong SJ, Kim ST, Kim TJ, Kim EO, Ahn CM, Park JH, et al. Cellular and molecular changes associated with inhibitory effect of pioglitazone on neointimal growth in patients with type 2 diabetes after zotarolimus-eluting stent implantation. <i>Arterioscler Thromb Vasc Biol<\/i> 2010; 30: 2655\u20132665.","DOI":"10.1161\/ATVBAHA.110.212670"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Fichtlscherer S, Zeiher AM, Dimmeler S. Circulating microRNAs: Biomarkers or mediators of cardiovascular diseases? <i>Arterioscler Thromb Vasc Biol<\/i> 2011; 31: 2383\u20132390.","DOI":"10.1161\/ATVBAHA.111.226696"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. De Rosa S, Curcio A, Indolfi C. Emerging role of microRNAs in cardiovascular diseases. <i>Circ J<\/i> 2014; 78: 567\u2013575.","DOI":"10.1253\/circj.CJ-14-0086"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Cheng Y, Liu X, Yang J, Lin Y, Xu DZ, Lu Q, et al. 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Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes. <i>Biomed Res Int<\/i> 2013; 2013: 201475, doi:10.1155\/2013\/201475.","DOI":"10.1155\/2013\/201475"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Kim YS, Kang HJ, Hong MH, Kang WS, Choe N, Kook H, et al. Angiopoietin-like 4 is involved in the poor angiogenic potential of high glucose-insulted bone marrow stem cells. <i>Korean Circ J<\/i> 2014; 44: 177\u2013183.","DOI":"10.4070\/kcj.2014.44.3.177"},{"key":"23","unstructured":"23. Li DF, Tian J, Guo X, Huang LM, Xu Y, Wang CC, et al. Induction of microRNA-24 by HIF-1 protects against ischemic injury in rat cardiomyocytes. <i>Physiol Res<\/i> 2012; 61: 555\u2013565."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Takayama K, Sukhova GK, Chin MT, Libby P. A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling. <i>Circ Res<\/i> 2006; 98: 499\u2013504.","DOI":"10.1161\/01.RES.0000204451.88147.96"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Cheang WS, Fang X, Tian XY. Pleiotropic effects of peroxisome proliferator-activated receptor gamma and delta in vascular diseases. <i>Circ J<\/i> 2013; 77: 2664\u20132671.","DOI":"10.1253\/circj.CJ-13-0647"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Mizoguchi M, Tahara N, Tahara A, Nitta Y, Kodama N, Oba T, et al. Pioglitazone attenuates atherosclerotic plaque inflammation in patients with impaired glucose tolerance or diabetes: A prospective, randomized, comparator-controlled study using serial FDG PET\/CT imaging study of carotid artery and ascending aorta. <i>JACC Cardiovasc Imaging<\/i> 2011; 4: 1110\u20131118.","DOI":"10.1016\/j.jcmg.2011.08.007"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Hong SJ, Shim WJ, Choi JI, Joo HJ, Shin SY, Park SM, et al. Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients. <i>Am J Cardiol<\/i> 2007; 100: 1625\u20131629.","DOI":"10.1016\/j.amjcard.2007.06.068"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Dohi T, Miyauchi K, Iesaki T, Tsuruta R, Tsuboi S, Ogita M, et al. Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents. <i>Circ J<\/i> 2011; 75: 1098\u20131106.","DOI":"10.1253\/circj.CJ-10-0917"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Nitta Y, Tahara N, Tahara A, Honda A, Kodama N, Mizoguchi M, et al. Pioglitazone decreases coronary artery inflammation in impaired glucose tolerance and diabetes mellitus: Evaluation by FDG-PET\/CT imaging. <i>JACC Cardiovasc Imaging<\/i> 2013; 6: 1172\u20131182.","DOI":"10.1016\/j.jcmg.2013.09.004"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Saremi A, Schwenke DC, Buchanan TA, Hodis HN, Mack WJ, Banerji M, et al. Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. <i>Arterioscler Thromb Vasc Biol<\/i> 2013; 33: 393\u2013399.","DOI":"10.1161\/ATVBAHA.112.300346"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Gilbert RE. Sodium-glucose linked transporter-2 inhibitors: Potential for renoprotection beyond blood glucose lowering? <i>Kidney Int<\/i> 2014; 86: 693\u2013700.","DOI":"10.1038\/ki.2013.451"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Hong SJ, Seo HS, Rha SW, Oh DJ, Kwon JA, Lee KN, et al. Decrease in plasma adiponectin concentrations in patients with variant angina pectoris. <i>Circ J<\/i> 2006; 70: 414\u2013418.","DOI":"10.1253\/circj.70.414"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Mirza S, Hossain M, Mathews C, Martinez P, Pino P, Gay JL, et al. Type 2-diabetes is associated with elevated levels of TNF-alpha, IL-6 and adiponectin and low levels of leptin in a population of Mexican Americans: A cross-sectional study. <i>Cytokine<\/i> 2012; 57: 136\u2013142.","DOI":"10.1016\/j.cyto.2011.09.029"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Calabro P, Willerson JT, Yeh ET. Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. <i>Circulation<\/i> 2003; 108: 1930\u20131932.","DOI":"10.1161\/01.CIR.0000096055.62724.C5"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, et al. 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