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Wilkoff BL, Cook JR, Epstein AE, Greene HL, Hallstrom AP, Hsia H, et al; Dual Chamber and VVI Implantable Defibrillator Trial Investigators. Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: The Dual Chamber And VVI Implantable Defibrillator (DAVID) Trial. <i>JAMA<\/i> 2002; 288: 3115\u20133123.","DOI":"10.1001\/jama.288.24.3115"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Sweeney MO, Hellkamp AS, Ellenbogen KA, Greenspon AJ, Freedman RA, Lee KL, et al; MOde Selection Trial Investigators. Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction. <i>Circulation<\/i> 2003; 107: 2932\u20132937.","DOI":"10.1161\/01.CIR.0000072769.17295.B1"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Nielsen JC, Kristensen L, Andersen HR, Mortensen PT, Pedersen OL, Pedersen AK. A randomized comparison of atrial and dual-chamber pacing in 177 consecutive patients with sick sinus syndrome: Echocardiographic and clinical outcome. <i>J Am Coll Cardiol<\/i> 2003; 42: 614\u2013623.","DOI":"10.1016\/S0735-1097(03)00757-5"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kristensen L, Nielsen JC, Mortensen PT, Pederden OL, Pedersen AK, Andersen HR. Incidence of atrial fibrillation and thromboembolism in a randomized trial of atrial versus dual chamber pacing in 177 patients with sick sinus syndrome. <i>Heart<\/i> 2004; 90: 661\u2013666.","DOI":"10.1136\/hrt.2003.016063"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Rosenqvist M, Brandt J, Sch\u00fcller H. Long-term pacing in sinus node disease: Effects of stimulation mode on cardiovascular morbidity and mortality. <i>Am Heart J<\/i> 1988; 116: 16\u201322.","DOI":"10.1016\/0002-8703(88)90244-X"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Rosenqvist M, Isaaz K, Botvinick E, Dae MW, Cockrell J, Abbott JA, et al. Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function. <i>Am J Cardiol<\/i> 1991; 67: 148\u2013156.","DOI":"10.1016\/0002-9149(91)90437-P"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Sgarbossa EB, Pinski SL, Maloney JD, Simmons TW, Wilkoff BL, Castle LW, et al. Chronic atrial fibrillation and stroke in paced patients with sick sinus syndrome: Relevance of clinical characteristics and pacing modalities. <i>Circulation<\/i> 1993; 88: 1045\u20131053.","DOI":"10.1161\/01.CIR.88.3.1045"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Leclercq C, Gras D, Le Helloco A, Nicol L, Mabo P, Daubert C. Hemodynamic importance of preserving the normal sequence of ventricular activation in permanent cardiac pacing. <i>Am Heart J<\/i> 1995; 129: 1133\u20131141.","DOI":"10.1016\/0002-8703(95)90394-1"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Andersen HR, Nielsen JC, Thomsen PE, Thuesen L, Mortensen PT, Vesterlund T, et al. Long-term follow-up of patients from a randomized trial of atrial versus ventricular pacing for sick-sinus syndrome. <i>Lancet<\/i> 1997; 350: 1210\u20131216.","DOI":"10.1016\/S0140-6736(97)03425-9"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Brandt J, Anderson H, F\u00e5hraeus T, Sch\u00fcller H. Natural history of sinus node disease treated with atrial pacing in 213 patients: Implications for selection of stimulation mode. <i>J Am Coll Cardiol<\/i> 1992; 20: 633\u2013639.","DOI":"10.1016\/0735-1097(92)90018-I"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kristensen L, Nielsen JC, Pedersen AK, Mortensen PT, Andersen HR. AV block and changes in pacing mode during long-term follow-up of 399 consecutive patients with sick sinus syndrome treated with an AAI\/AAIR pacemaker. <i>Pacing Clin Electrophysiol<\/i> 2001; 24: 358\u2013365.","DOI":"10.1046\/j.1460-9592.2001.00358.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Matsumoto H, Ueda Y, Kato R, Usui A, Maseki T, Takagi Y, et al. Long-term clinical performance of AAI pacing in patients with sick sinus syndrome: A comparison with dual-chamber pacing. <i>Europace<\/i> 2004; 6: 444\u2013450.","DOI":"10.1016\/j.eupc.2004.05.003"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. H\u00f6ijer CJ, H\u00f6glund P, Sch\u00fcller H, Brandt J. 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A new dual-chamber pacing mode to minimize ventricular pacing. <i>Pacing Clin Electrophysiol<\/i> 2005; 28: S43\u2013S46.","DOI":"10.1111\/j.1540-8159.2005.00095.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Frohlig G, Gras D, Victor J, Mabo P, Galley D, Savoure A, et al. Performance of a new cardiac pacing mode designed to eliminate unnecessary ventricular pacing. <i>Europace<\/i> 2006; 8: 96\u2013101.","DOI":"10.1093\/europace\/euj024"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. JCS Joint Working Group. Guidelines for non-pharmacotherapy of cardiac arrhythmias (JCS 2011): Digest version. <i>Circ J<\/i> 2013; 77: 249\u2013274.","DOI":"10.1253\/circj.CJ-66-0054"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. JCS Joint Working Group. Guidelines for clinical cardiac electrophysiologic studies (JCS 2011): Digest version. <i>Circ J<\/i> 2013; 77: 497\u2013518.","DOI":"10.1253\/circj.CJ-66-0055"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Sweeney MO, Bank AJ, Nsah E, Koullick M, Zeng QC, Hettrick D, et al. Search AV Extension and Managed Ventricular Pacing for Promoting Atrioventricular Conduction (SAVE PACe) Trial: Minimizing ventricular pacing to reduce atrial fibrillation in sinus-node disease. <i>N Engl J Med<\/i> 2007; 357: 1000\u20131008.","DOI":"10.1056\/NEJMoa071880"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Pioger G, Leny G, Nitzsche R, Ripart A. AAIsafeR limits ventricular pacing in unselected patients. <i>Pacing Clin Electrophysiol<\/i> 2007; 30: S66\u2013S70.","DOI":"10.1111\/j.1540-8159.2007.00608.x"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Davy JM, Hoffmann E, Frey A, Jocham K, Rossi S, Dupuis JM, et al. Near elimination of ventricular pacing in SafeR mode compared to DDD modes: A randomized study of 422 patients. <i>Pacing Clin Electrophysiol<\/i> 2012; 35: 392\u2013402.","DOI":"10.1111\/j.1540-8159.2011.03314.x"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Thibault B, Simpson C, Gagn\u00e9 CE, Blier L, Senaratne M, McNicoll S, et al. Impact of AV conduction disorders on SafeR mode performance. <i>Pacing Clin Electrophysiol<\/i> 2009; 32: S231\u2013S235.","DOI":"10.1111\/j.1540-8159.2008.02293.x"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Nowak B, McMeekin J, Knops M, Wille B, Schr\u00f6der E, Moro C, et al; Stored EGM in Pulsar Max II and Discovery II Study Group. Validation of dual-chamber pacemaker diagnostic data using dual-channel stored electrograms. <i>Pacing Clin Electrophysiol<\/i> 2005; 28: 620\u2013629.","DOI":"10.1111\/j.1540-8159.2005.00159.x"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Nowak B, Sperzel J, Rauscha F, Mont L, Alzueta J, Senden PJ, et al. Diagnostic value of onset-recordings and marker annotations in dual chamber pacemaker stored electrograms. <i>Europace<\/i> 2003; 5: 103\u2013109.","DOI":"10.1053\/eupc.2002.0276"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Kaufman ES, Israel CW, Nair GM, Armaganijan L, Divakaramenon S, Mairesse GH, et al; ASSERT Steering Committee and Investigators. Positive predictive value of device-detected atrial high-rate episodes at different rates and durations: An analysis from ASSERT. <i>Heart Rhythm<\/i> 2012; 9: 1241\u20131246.","DOI":"10.1016\/j.hrthm.2012.03.017"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Prystowsky EN. The effects of slow channel blockers and beta blockers on atrioventricular nodal conduction. <i>J Clin Pharmacol<\/i> 1988; 28: 6\u201321.","DOI":"10.1002\/j.1552-4604.1988.tb03095.x"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. 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