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Marsalese DL, Moodie DS, Vacante M, Lytle BW, Gill CC, Sterba R, et al. Marfan\u2019s syndrome: Natural history and long-term follow-up of cardiovascular involvement. <i>J Am Coll Cardiol<\/i> 1989; 14: 422\u2013431.","DOI":"10.1016\/0735-1097(89)90197-6"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Loeys BL, Schwarze U, Holm T, Callewaert BL, Thomas GH, Pannu H, et al. Aneurysm syndromes caused by mutations in the TGF-beta receptor. <i>N Engl J Med<\/i> 2006; 355: 788\u2013798.","DOI":"10.1056\/NEJMoa055695"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Jondeau G, Detaint D, Tubach F, Arnoult F, Milleron O, Raoux F, et al. Aortic event rate in the Marfan population: A cohort study. <i>Circulation<\/i> 2012; 125: 226\u2013232.","DOI":"10.1161\/CIRCULATIONAHA.111.054676"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Meijboom LJ, Timmermans J, Zwinderman AH, Engelfriet PM, Mulder BJ. Aortic root growth in men and women with the Marfan\u2019s syndrome. <i>Am J Cardiol<\/i> 2005; 96: 1441\u20131444.","DOI":"10.1016\/j.amjcard.2005.06.094"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Maleszewski JJ, Miller DV, Lu J, Dietz HC, Halushka MK. Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS). <i>Am J Surg Pathol<\/i> 2009; 33: 194\u2013201.","DOI":"10.1097\/PAS.0b013e31817f3661"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Okamoto RJ, Xu H, Kouchoukos NT, Moon MR, Sundt TM 3rd. The influence of mechanical properties on wall stress and distensibility of the dilated ascending aorta. <i>J Thorac Cardiovasc Surg<\/i> 2003; 126: 842\u2013850.","DOI":"10.1016\/S0022-5223(03)00728-1"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Marque V, Kieffer P, Gayraud B, Lartaud-Idjouadiene I, Ramirez F, Atkinson J. 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Hirata K, Triposkiadis F, Sparks E, Bowen J, Wooley CF, Boudoulas H. The Marfan syndrome: Abnormal aortic elastic properties. <i>J Am Coll Cardiol<\/i> 1991; 18: 57\u201363.","DOI":"10.1016\/S0735-1097(10)80218-9"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Baumgartner D, Baumgartner C, M\u00e1ty\u00e1s G, Steinmann B, L\u00f6ffler-Ragg J, Schermer E, et al. Diagnostic power of aortic elastic properties in young patients with Marfan syndrome. <i>J Thorac Cardiovasc Surg<\/i> 2005; 129: 730\u2013739.","DOI":"10.1016\/j.jtcvs.2004.07.019"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Singh MN, Lacro RV. Recent clinical drug trials evidence in Marfan syndrome and clinical implications. <i>Can J Cardiol<\/i> 2016; 32: 66\u201377.","DOI":"10.1016\/j.cjca.2015.11.003"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Loeys BL, Dietz HC, Braverman AC, Callewaert BL, De Backer J, Devereux RB, et al. The revised Ghent nosology for the Marfan syndrome. <i>J Med Genet<\/i> 2010; 47: 476\u2013485.","DOI":"10.1136\/jmg.2009.072785"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Lopez L, Colan SD, Frommelt PC, Ensing GJ, Kendall K, Younoszai AK, et al. Recommendations for quantification methods during the performance of a pediatric echocardiogram: A report from the Pediatric Measurements Writing Group of the American Society of Echocardiography Pediatric and Congenital Heart Disease Council. <i>J Am Soc Echocardiogr<\/i> 2010; 23: 465\u2013495.","DOI":"10.1016\/j.echo.2010.03.019"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Oyamada J, Toyono M, Shimada S, Aoki-Okazaki M, Takahashi T. Altered central aortic elastic properties in Kawasaki disease are related to changes in left ventricular geometry and coronary artery aneurysm formation. <i>J Am Soc Echocardiogr<\/i> 2012; 25: 690\u2013696.","DOI":"10.1016\/j.echo.2012.03.003"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Pettersen MD, Du W, Skeens ME, Humes RA. Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: An echocardiographic study. <i>J Am Soc Echocardiogr<\/i> 2008; 21: 922\u2013934.","DOI":"10.1016\/j.echo.2008.02.006"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Gautier M, Detaint D, Fermanian C, Aegerter P, Delorme G, Arnoult F, et al. Nomograms for aortic root diameters in children using two-dimensional echocardiography. <i>Am J Cardiol<\/i> 2010; 105: 888\u2013894.","DOI":"10.1016\/j.amjcard.2009.11.040"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Oulego-Erroz I, Alonso-Quintela P, Mora-Matilla M, Gautreaux Minaya S, Lape\u00f1a-L\u00f3pez de Armentia S. Ascending aorta elasticity in children with isolated bicuspid aortic valve. <i>Int J Cardiol<\/i> 2013; 168: 1143\u20131146.","DOI":"10.1016\/j.ijcard.2012.11.080"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Weismann CG, Lombardi KC, Grell BS, Northrup V, Sugeng L. Aortic stiffness and left ventricular diastolic function in children with well-functioning bicuspid aortic valves. <i>Eur Heart J Cardiovasc Imaging<\/i> 2016; 17: 225\u2013230.","DOI":"10.1093\/ehjci\/jev151"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Nakagawa R, Kuwata S, Kurishima C, Saiki H, Iwamoto Y, Sugimoto M, et al. Arterial stiffness in patients after Kawasaki disease without coronary artery involvement: Assessment by performing brachial ankle pulse wave velocity and cardio-ankle vascular index. <i>J Cardiol<\/i> 2015; 66: 130\u2013134.","DOI":"10.1016\/j.jjcc.2014.10.003"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Kojima T, Kuwata S, Kurishima C, Iwamoto Y, Saiki H, Ishido H, et al. Aortic root dilatation and aortic stiffness in patients with single ventricular circulation. <i>Circ J<\/i> 2014; 78: 2507\u20132511.","DOI":"10.1253\/circj.CJ-13-1264"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Kiotsekoglou A, Moggridge JC, Saha SK, Kapetanakis V, Govindan M, Alpendurada F, et al. Assessment of aortic stiffness in Marfan syndrome using two-dimensional and Doppler echocardiography. <i>Echocardiography<\/i> 2011; 28: 29\u201337.","DOI":"10.1111\/j.1540-8175.2010.01241.x"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Seki M, Kurishima C, Saiki H, Masutani S, Arakawa H, Tamura M, et al. Progressive aortic dilation and aortic stiffness in children with repaired tetralogy of Fallot. <i>Heart Vessels<\/i> 2014; 29: 83\u201387.","DOI":"10.1007\/s00380-013-0326-1"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Rios AS, Silber EN, Bavishi N, Varga P, Burton BK, Clark WA, et al. Effect of long-term beta-blockade on aortic root compliance in patients with Marfan syndrome. <i>Am Heart J<\/i> 1999; 137: 1057\u20131061.","DOI":"10.1016\/S0002-8703(99)70362-5"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Groenink M, de Roos A, Mulder BJ, Spaan JA, van der Wall EE. Changes in aortic distensibility and pulse wave velocity assessed with magnetic resonance imaging following beta-blocker therapy in the Marfan syndrome. <i>Am J Cardiol<\/i> 1998; 82: 203\u2013208.","DOI":"10.1016\/S0002-9149(98)00315-4"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Sandor GG, Alghamdi MH, Raffin LA, Potts MT, Williams LD, Potts JE, et al. A randomized, double blind pilot study to assess the effects of losartan vs. atenolol on the biophysical properties of the aorta in patients with Marfan and Loeys-Dietz syndromes. <i>Int J Cardiol<\/i> 2015; 179: 470\u2013475.","DOI":"10.1016\/j.ijcard.2014.11.082"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Bhatt AB, Buck JS, Zuflacht JP, Milian J, Kadivar S, Gauvreau K, et al. Distinct effects of losartan and atenolol on vascular stiffness in Marfan syndrome. <i>Vasc Med<\/i> 2015; 20: 317\u2013325.","DOI":"10.1177\/1358863X15569868"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Lacro RV, Dietz HC, Sleeper LA, Yetman AT, Bradley TJ, Colan SD, et al. Atenolol versus losartan in children and young adults with Marfan\u2019s syndrome. <i>N Engl J Med<\/i> 2014; 371: 2061\u20132071.","DOI":"10.1056\/NEJMoa1404731"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. 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Aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive subjects. <i>Hypertension<\/i> 2005; 45: 426\u2013431.","DOI":"10.1161\/01.HYP.0000157818.58878.93"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Levy D, et al. Aortic stiffness, blood pressure progression, and incident hypertension. <i>JAMA<\/i> 2012; 308: 875\u2013881.","DOI":"10.1001\/2012.jama.10503"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Stefanadis C, Stratos C, Boudoulas H, Kourouklis C, Toutouzas P. 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