{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T13:34:54Z","timestamp":1780925694423,"version":"3.54.1"},"reference-count":23,"publisher":"Japanese Circulation Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Circ J"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1253\/circj.cj-16-1193","type":"journal-article","created":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T22:06:59Z","timestamp":1495836419000},"page":"1654-1661","source":"Crossref","is-referenced-by-count":53,"title":["Imbalanced Angiogenesis in Peripartum Cardiomyopathy\u3000\u2015 Diagnostic Value of Placenta Growth Factor \u2015"],"prefix":"10.1253","volume":"81","author":[{"given":"Alexandre","family":"Mebazaa","sequence":"first","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-France","family":"Seronde","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Department of Cardiology EA3920, University Hospital Jean Minjoz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Gayat","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemi","family":"Tibazarwa","sequence":"additional","affiliation":[{"name":"Hatter Institute for Cardiovascular Research in Africa and MRC Inter-Cape Heart Unit, Department of Medicine, Faculty of Health Sciences, University of Cape Town"},{"name":"Soweto Cardiovascular Research Unit, University of the Witwatersrand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilly O.C.","family":"Anumba","sequence":"additional","affiliation":[{"name":"Gynecology, Obstetric, Academic Unit of Reproductive and Developmental Medicine, The University of Sheffield Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najla","family":"Akrout","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malha","family":"Sadoune","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamela","family":"Sarb","sequence":"additional","affiliation":[{"name":"Gynecology, Obstetric, Academic Unit of Reproductive and Developmental Medicine, The University of Sheffield Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattia","family":"Arrigo","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justina","family":"Motiejunaite","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Laribi","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Department of Emergency Medicine, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Legrand","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Deschamps","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bichat Hospital, AP-HP"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loubina","family":"Fazal","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila","family":"Bouadma","sequence":"additional","affiliation":[{"name":"Department of Medical ICU, Bichat Hospital, AP-HP"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Collet","sequence":"additional","affiliation":[{"name":"Biochemistry Department, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Manivet","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Biochemistry Department, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain Cohen","family":"Solal","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"},{"name":"Department of Cardiology, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marie","family":"Launay","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Biochemistry Department, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"},{"name":"Paris Descartes University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane-Lise","family":"Samuel","sequence":"additional","affiliation":[{"name":"UMR-S 942 INSERM, Lariboisi\u00e8re Hospital"},{"name":"Paris Diderot University, Sorbonne Paris Cit\u00e9"},{"name":"Department of Anaesthesiology and Critical Care, Lariboisi\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Sliwa","sequence":"additional","affiliation":[{"name":"Hatter Institute for Cardiovascular Research in Africa and MRC Inter-Cape Heart Unit, Department of Medicine, Faculty of Health Sciences, University of Cape Town"},{"name":"Soweto Cardiovascular Research Unit, University of the Witwatersrand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"330","reference":[{"key":"1","unstructured":"1. Sliwa K, Bohm M. Incidence and prevalence of pregnancy-related heart disease. <i>Cardiovasc Res<\/i> 2014; 101: 554\u2013560."},{"key":"2","unstructured":"2. Kassebaum NJ, Bertozzi-Villa A, Coggeshall MS, Shackelford KA, Steiner C, Heuton KR, et al. Global, regional, and national levels and causes of maternal mortality during 1990\u20132013: A systematic analysis for the Global Burden of Disease Study 2013. <i>Lancet<\/i> 2014; 384: 980\u20131004."},{"key":"3","unstructured":"3. Hilfiker-Kleiner D, Haghikia A, Nonhoff J, Bauersachs J. Peripartum cardiomyopathy: Current management and future perspectives. <i>Eur Heart J<\/i> 2015; 36: 1090\u20131097."},{"key":"4","unstructured":"4. Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. <i>Lancet<\/i> 2006; 368: 687\u2013693."},{"key":"5","unstructured":"5. Hilfiker-Kleiner D, Sliwa K. Pathophysiology and epidemiology of peripartum cardiomyopathy. <i>Nat Rev Cardiol<\/i> 2014; 11: 364\u2013370."},{"key":"6","unstructured":"6. Ntusi NB, Badri M, Gumedze F, Sliwa K, Mayosi BM. Pregnancy-associated heart failure: A comparison of clinical presentation and outcome between hypertensive heart failure of pregnancy and idiopathic peripartum cardiomyopathy. <i>PLoS One<\/i> 2015; 10: e0133466."},{"key":"7","unstructured":"7. Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, et al. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. <i>Nature<\/i> 2012; 485: 333\u2013338."},{"key":"8","unstructured":"8. Lecarpentier E, Tsatsaris V. Angiogenic balance (sFlt-1\/PlGF) and preeclampsia. <i>Ann Endocrinol (Paris)<\/i> 2016; 77: 97\u2013100."},{"key":"9","unstructured":"9. Blauwet LA, Libhaber E, Forster O, Tibazarwa K, Mebazaa A, Hilfiker-Kleiner D, et al. Predictors of outcome in 176 South African patients with peripartum cardiomyopathy. <i>Heart<\/i> 2013; 99: 308\u2013313."},{"key":"10","unstructured":"10. Lassus J, Gayat E, Mueller C, Peacock WF, Spinar J, Harjola VP, et al. Incremental value of biomarkers to clinical variables for mortality prediction in acutely decompensated heart failure: The Multinational Observational Cohort on Acute Heart Failure (MOCA) study. <i>Int J Cardiol<\/i> 2013; 168: 2186\u20132194."},{"key":"11","unstructured":"11. Camors E, Charue D, Trouve P, Monceau V, Loyer X, Russo-Marie F, et al. Association of annexin A5 with Na<sup>+<\/sup>\/Ca<sup>2+<\/sup> exchanger and caveolin-3 in non-failing and failing human heart. <i>J Mol Cell Cardiol<\/i> 2006; 40: 47\u201355."},{"key":"12","unstructured":"12. Seno A, Takeda Y, Matsui M, Okuda A, Nakano T, Nakada Y, et al. Suppressed production of soluble Fms-like tyrosine kinase-1 contributes to myocardial remodeling and heart failure. <i>Hypertension<\/i> 2016; 68: 678\u2013687."},{"key":"13","unstructured":"13. Ghosh RK, Banerjee K, Tummala R, Ball S, Ravakhah K, Gupta A. Serelaxin in acute heart failure: Most recent update on clinical and preclinical evidence. <i>Cardiovasc Ther<\/i> 2017; 35: 55\u201363."},{"key":"14","unstructured":"14. Sliwa K, Hilfiker-Kleiner D, Petrie MC, Mebazaa A, Pieske B, Buchmann E, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: A position statement from the Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy. <i>Eur J Heart Fail<\/i> 2010; 12: 767\u2013778."},{"key":"15","unstructured":"15. Fisher C, Berry C, Blue L, Morton JJ, McMurray J. N-Terminal pro B type natriuretic peptide, but not the new putative cardiac hormone relaxin, predicts prognosis in patients with chronic heart failure. <i>Heart<\/i> 2003; 89: 879\u2013881."},{"key":"16","unstructured":"16. Anumba DO, El Gelany S, Elliott SL, Li TC. Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester. <i>Eur J Obstet Gynecol Reprod Biol<\/i> 2009; 147: 41\u201345."},{"key":"17","unstructured":"18. Sliwa K, Hilfiker-Kleiner D, Mebazaa A, Petrie MC, Maggioni AP, Regitz-Zagrosek V, et al. EURObservational Research Programme: A worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM. <i>Eur J Heart Fail<\/i> 2014; 16: 583\u2013591."},{"key":"18","unstructured":"19. Palm M, Basu S, Larsson A, Wernroth L, \u00c5kerud H, Axelsson O. A longitudinal study of plasma levels of soluble fms-like tyrosine kinase 1 (sFlt1), placental growth factor (PlGF), sFlt1: PlGF ratio and vascular endothelial growth factor (VEGF-A) in normal pregnancy. <i>Acta Obstet Gynecol Scand<\/i> 2011; 90: 1244\u20131251."},{"key":"19","unstructured":"20. Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, et al. A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. <i>Cell<\/i> 2007; 128: 589\u2013600."},{"key":"20","unstructured":"21. Hilfiker-Kleiner D, Struman I, Hoch M, Podewski E, Sliwa K. 16-kDa prolactin and bromocriptine in postpartum cardiomyopathy. <i>Curr Heart Fail Rep<\/i> 2012; 9: 174\u2013182."},{"key":"21","unstructured":"22. McGuane JT, Debrah JE, Debrah DO, Rubin JP, Segal M, Shroff SG, et al. Role of relaxin in maternal systemic and renal vascular adaptations during gestation. <i>Ann N Y Acad Sci<\/i> 2009; 1160: 304\u2013312."},{"key":"22","unstructured":"23. Halkein J, Tabruyn SP, Ricke-Hoch M, Haghikia A, Nguyen NQ, Scherr M, et al. MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. <i>J Clin Invest<\/i> 2013; 123: 2143\u20132154."},{"key":"23","unstructured":"24. Sliwa K, Mebazaa A. Possible joint pathways of early pre-eclampsia and congenital heart defects via angiogenic imbalance and potential evidence for cardio-placental syndrome. <i>Eur Heart J<\/i> 2014; 35: 680\u2013682."}],"container-title":["Circulation Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/81\/11\/81_CJ-16-1193\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,28]],"date-time":"2017-10-28T03:47:30Z","timestamp":1509162450000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/81\/11\/81_CJ-16-1193\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1253\/circj.cj-16-1193","relation":{},"ISSN":["1346-9843","1347-4820"],"issn-type":[{"value":"1346-9843","type":"print"},{"value":"1347-4820","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}