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Kannel WB. Incidence and epidemiology of heart failure. <i>Heart Fail Rev<\/i> 2000; 5: 167\u2013173."},{"key":"2","unstructured":"2. Stewart S, MacIntyre K, Hole DJ, Capewell S, McMurray JJ. More \u2018malignant\u2019 than cancer?: Five-year survival following a first admission for heart failure. <i>Eur J Heart Fail<\/i> 2001; 3: 315\u2013322."},{"key":"3","unstructured":"3. Ambrosy AP, Fonarow GC, Butler J, Chioncel O, Greene SJ, Vaduganathan M, et al. The global health and economic burden of hospitalizations for heart failure: Lessons learned from hospitalized heart failure registries. <i>J Am Coll Cardiol<\/i> 2014; 63: 1123\u20131133."},{"key":"4","unstructured":"4. Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D\u2019Agostino RB, Kannel WB, et al. Lifetime risk for developing congestive heart failure: The Framingham Heart Study. <i>Circulation<\/i> 2002; 106: 3068\u20133072."},{"key":"5","unstructured":"5. Berry JD, Dyer A, Cai X, Garside DB, Ning H, Thomas A, et al. 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Kubota Y, Oike Y, Satoh S, Tabata Y, Niikura Y, Morisada T, et al. Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development. <i>Proc Natl Acad Sci U S A<\/i> 2005; 102: 13502\u201313507."},{"key":"11","unstructured":"11. Oike Y, Tian Z, Miyata K, Morinaga J, Endo M, Kadomatsu T. ANGPTL2: A new causal player in accelerating heart disease development in the aging. <i>Circ J<\/i> 2017; 81: 1379\u20131385."},{"key":"12","unstructured":"12. Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, et al. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. <i>Cell Metab<\/i> 2009; 10: 178\u2013188."},{"key":"13","unstructured":"13. Tazume H, Miyata K, Tian Z, Endo M, Horiguchi H, Takahashi O, et al. 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ACC\/AHA\/ASE 2003 guideline update for the clinical application of echocardiography: Summary article: A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (ACC\/AHA\/ASE Committee to Update the 1997 Guidelines for the Clinical Application of Echocardiography). <i>Circulation<\/i> 2003; 108: 1146\u20131162."},{"key":"25","unstructured":"25. Oka T, Maillet M, Watt AJ, Schwartz RJ, Aronow BJ, Duncan SA, et al. Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. <i>Circ Res<\/i> 2006; 98: 837\u2013845."},{"key":"26","unstructured":"26. Morinaga J, Kadomatsu T, Miyata K, Endo M, Terada K, Tian Z, et al. Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-beta signaling in chronic kidney disease. <i>Kidney Int<\/i> 2016; 89: 327\u2013341."},{"key":"27","unstructured":"27. Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, et al. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. <i>Nature<\/i> 2007; 446: 444\u2013448."},{"key":"28","unstructured":"28. Ashrafian H, Frenneaux MP, Opie LH. Metabolic mechanisms in heart failure. <i>Circulation<\/i> 2007; 116: 434\u2013448."},{"key":"29","unstructured":"29. Witteles RM, Fowler MB. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. <i>J Am Coll Cardiol<\/i> 2008; 51: 93\u2013102."},{"key":"30","unstructured":"30. Shimizu I, Yoshida Y, Katsuno T, Tateno K, Okada S, Moriya J, et al. p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. <i>Cell Metab<\/i> 2012; 15: 51\u201364."},{"key":"31","unstructured":"31. Opie LH. 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