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Carvedilol improves left ventricular function in heart failure patients with idiopathic dilated cardiomyopathy and a wide range of sympathetic nervous system function as measured by iodine 123 metaiodobenzylguanidine. <i>J Nucl Cardiol<\/i> 2002; 9: 608\u2013615.","DOI":"10.1067\/mnc.2002.127717"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. De Matos LD, Gardenghi G, Rondon MU, Soufen HN, Tirone AP, Barretto AC, et al. Impact of 6 months of therapy with carvedilol on muscle sympathetic nerve activity in heart failure patients. <i>J Card Fail<\/i> 2004; 10: 496\u2013502.","DOI":"10.1016\/j.cardfail.2004.03.006"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Granger CB, McMurray JJ, Yusuf S, Held P, Michelson EL, Olofsson B, et al; CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARM-Alternative trial. <i>Lancet<\/i> 2003; 362: 772\u2013776.","DOI":"10.1016\/S0140-6736(03)14284-5"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). <i>N Engl J Med<\/i> 1987; 316: 1429\u20131435.","DOI":"10.1056\/NEJM198706043162301"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Packer M, Coats AJ, Fowler MB, Katus HA, Krum H, Mohacsi P, et al; Carvedilol Prospective Randomized Cumulative Survival Study Group. 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Early clinical and echocardiographic outcomes after SAPIEN 3 transcatheter aortic valve replacement in inoperable, high-risk and intermediate-risk patients with aortic stenosis. <i>Eur Heart J<\/i> 2016; 37: 2252\u20132262.","DOI":"10.1093\/eurheartj\/ehw112"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Jacobson AF, Senior R, Cerqueira MD, Wong ND, Thomas GS, Lopez VA, et al. Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure: Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study. <i>J Am Coll Cardiol<\/i> 2010; 55: 2212\u20132221.","DOI":"10.1016\/j.jacc.2010.01.014"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Verschure DO, Veltman CE, Manrique A, Somsen GA, Koutelou M, Katsikis A, et al. 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Watson AM, Hood SG, May CN. Mechanisms of sympathetic activation in heart failure. <i>Clin Exp Pharmacol Physiol<\/i> 2006; 33: 1269\u20131274.","DOI":"10.1111\/j.1440-1681.2006.04523.x"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Li YF, Wang W, Mayhan WG, Patel KP. Angiotensin-mediated increase in renal sympathetic nerve discharge within the PVN: Role of nitric oxide. <i>Am J Physiol Regul Integr Comp Physiol<\/i> 2006; 290: R1035\u2013R1043.","DOI":"10.1152\/ajpregu.00338.2004"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Garrido AM, Griendling KK. NADPH oxidases and angiotensin II receptor signaling. <i>Mol Cell Endocrinol<\/i> 2009; 302: 148\u2013158.","DOI":"10.1016\/j.mce.2008.11.003"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Bristow MR, Ginsburg R, Minobe W, Cubicciotti RS, Sageman WS, Lurie K, et al. 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Heart failure in severe aortic valve stenosis: Prognostic impact of left ventricular ejection fraction and mean gradient on outcome after transcatheter aortic valve implantation. <i>Eur J Heart Fail<\/i> 2012; 14: 1155\u20131162.","DOI":"10.1093\/eurjhf\/hfs108"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Dumonteil N, Vaccaro A, Despas F, Labrunee M, Marcheix B, Lambert E, et al. Transcatheter aortic valve implantation reduces sympathetic activity and normalizes arterial spontaneous baroreflex in patients with aortic stenosis. <i>JACC Cardiovasc Interv<\/i> 2013; 6: 1195\u20131202.","DOI":"10.1016\/j.jcin.2013.06.012"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Weiss ML, Claassen DE, Hirai T, Kenney MJ. Nonuniform sympathetic nerve responses to intravenous hypertonic saline infusion. <i>J Auto Nerv Syst<\/i> 1996; 57: 109\u2013115.","DOI":"10.1016\/0165-1838(95)00108-5"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42. 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