{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:53:56Z","timestamp":1790963636435,"version":"4.1.0"},"reference-count":28,"publisher":"Japanese Circulation Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Circ J"],"published-print":{"date-parts":[[2019,10,25]]},"DOI":"10.1253\/circj.cj-19-0515","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T18:03:55Z","timestamp":1568916235000},"page":"2271-2281","source":"Crossref","is-referenced-by-count":90,"title":["Cancer-Associated Venous Thromboembolism in the Real World\u3000\u2015 From the COMMAND VTE Registry \u2015"],"prefix":"10.1253","volume":"83","author":[{"given":"Jiro","family":"Sakamoto","sequence":"first","affiliation":[{"name":"Department of Cardiology, Tenri Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yugo","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Morimoto","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Hyogo College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidewo","family":"Amano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kurashiki Central Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Takase","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kindai University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiichi","family":"Hiramori","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kokura Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Oi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Japanese Red Cross Otsu Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Akao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Kyoto Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Center, Osaka Red Cross Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoru","family":"Toyofuku","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Japanese Red Cross Wakayama Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Izumi","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohisa","family":"Tada","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shizuoka General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Min","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka Saiseikai Noe Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Murata","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shizuoka City Shizuoka Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Tsuyuki","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Shimada Municipal Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syunsuke","family":"Saga","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Nishimoto","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Sasa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kishiwada City Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minako","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Nishikobe Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonori","family":"Togi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Nara Hospital, Kindai University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Mabuchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Koto Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Takabayashi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hirakata Kohsai Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Shiomi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeru","family":"Makiyama","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koh","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tenri Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihisa","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Shiga University of Medical Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the COMMAND VTE Registry Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"330","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. <i>CA Cancer J Clin<\/i> 2019; 69: 7\u201334.","DOI":"10.3322\/caac.21551"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Ito Y, Miyashiro I, Ito H, Hosono S, Chihara D, Nakata-Yamada K, et al. Long-term survival and conditional survival of cancer patients in Japan using population-based cancer registry data. <i>Cancer Sci<\/i> 2014; 105: 1480\u20131486.","DOI":"10.1111\/cas.12525"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Blom JW, Doggen CJ, Osanto S, Rosendaal FR. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. <i>JAMA<\/i> 2005; 293: 715\u2013722.","DOI":"10.1001\/jama.293.6.715"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Khorana AA. Venous thromboembolism and prognosis in cancer. <i>Thromb Res<\/i> 2010; 125: 490\u2013493.","DOI":"10.1016\/j.thromres.2009.12.023"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Mukai M, Oka T. Mechanism and management of cancer-associated thrombosis. <i>J Cardiol<\/i> 2018; 72: 89\u201393.","DOI":"10.1016\/j.jjcc.2018.02.011"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Walker AJ, Card TR, West J, Crooks C, Grainge MJ. Incidence of venous thromboembolism in patients with cancer: A cohort study using linked United Kingdom databases. <i>Eur J Cancer<\/i> 2013; 49: 1404\u20131413.","DOI":"10.1016\/j.ejca.2012.10.021"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Prandoni P, Lensing AW, Piccioli A, Bernardi E, Simioni P, Girolami B, et al. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. <i>Blood<\/i> 2002; 100: 3484\u20133488.","DOI":"10.1182\/blood-2002-01-0108"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. JCS Joint Working Group. Guidelines for the diagnosis, treatment and prevention of pulmonary thromboembolism and deep vein thrombosis (JCS 2009): Digest version. <i>Circ J<\/i> 2011; 75: 1258\u20131281.","DOI":"10.1253\/circj.CJ-88-0010"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Yamashita Y, Morimoto T, Amano H, Takase T, Hiramori S, Kim K, et al. Anticoagulation therapy for venous thromboembolism in the real world: From the COMMAND VTE Registry. <i>Circ J<\/i> 2018; 82: 1262\u20131270.","DOI":"10.1253\/circj.CJ-17-1128"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Yamashita Y, Morimoto T, Amano H, Takase T, Hiramori S, Kim K, et al. Influence of baseline platelet count on outcomes in patients with venous thromboembolism (from the COMMAND VTE Registry). <i>Am J Cardiol<\/i> 2018; 122: 2131\u20132141.","DOI":"10.1016\/j.amjcard.2018.08.053"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. B\u00fcller HR, D\u00e9cousus H, Grosso MA, Mercuri M, Middeldorp S, Prins MH, et al. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. <i>N Engl J Med<\/i> 2013; 369: 1406\u20131415.","DOI":"10.1056\/NEJMoa1306638"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Schulman S, Kearon C; Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. <i>J Thromb Haemost<\/i> 2005; 3: 692\u2013694.","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Faller N, Limacher A, Mean M, Righini M, Aschwanden M, Beer JH, et al. Predictors and causes of long-term mortality in elderly patients with acute venous thromboembolism: A prospective cohort study. <i>Am J Med<\/i> 2017; 130: 198\u2013206.","DOI":"10.1016\/j.amjmed.2016.09.008"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Rosendaal FR, Cannegieter SC, van der Meer FJ, Briet E. A method to determine the optimal intensity of oral anticoagulant therapy. <i>Thromb Haemost<\/i> 1993; 69: 236\u2013239.","DOI":"10.1055\/s-0038-1651587"},{"key":"15","unstructured":"15. Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Gali\u00e8 N, et al. 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. <i>Eur Heart J<\/i> 2014; 35: 3033\u20133069, 3069a\u20133069k."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, et al. Antithrombotic therapy for VTE disease: CHEST Guideline and Expert Panel Report. <i>Chest<\/i> 2016; 149: 315\u2013352.","DOI":"10.1016\/j.chest.2015.11.026"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: A Scientific Statement from the American Heart Association. <i>Circulation<\/i> 2011; 123: 1788\u20131830.","DOI":"10.1161\/CIR.0b013e318214914f"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Raskob GE, van Es N, Segers A, Angchaisuksiri P, Oh D, Boda Z, et al. Edoxaban for venous thromboembolism in patients with cancer: Results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial. <i>Lancet Haematol<\/i> 2016; 3: e379\u2013e387.","DOI":"10.1016\/S2352-3026(16)30057-6"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Agnelli G, Buller HR, Cohen A, Gallus AS, Lee TC, Pak R, et al. Oral apixaban for the treatment of venous thromboembolism in cancer patients: Results from the AMPLIFY trial. <i>J Thromb Haemost<\/i> 2015; 13: 2187\u20132191.","DOI":"10.1111\/jth.13153"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Schwarzbach CJ, Schaefer A, Ebert A, Held V, Bolognese M, Kablau M, et al. Stroke and cancer: The importance of cancer-associated hypercoagulation as a possible stroke etiology. <i>Stroke<\/i> 2012; 43: 3029\u20133034.","DOI":"10.1161\/STROKEAHA.112.658625"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. <i>Chest<\/i> 2012; 141: e419S\u2013e496S.","DOI":"10.1378\/chest.11-2301"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Elalamy I, Mah\u00e9 I, Ageno W, Meyer G. Long-term treatment of cancer-associated thrombosis: The choice of the optimal anticoagulant. <i>J Thromb Haemost<\/i> 2017; 15: 848\u2013857.","DOI":"10.1111\/jth.13659"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Raskob GE, van Es N, Verhamme P, Carrier M, Di Nisio M, Garcia D, et al. Edoxaban for the treatment of cancer-associated venous thromboembolism. <i>N Engl J Med<\/i> 2018; 378: 615\u2013624.","DOI":"10.1056\/NEJMoa1711948"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Young AM, Marshall A, Thirlwall J, Chapman O, Lokare A, Hill C, et al. Comparison of an oral factor Xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism: Results of a randomized trial (SELECT-D). <i>J Clin Oncol<\/i> 2018; 36: 2017\u20132023.","DOI":"10.1200\/JCO.2018.78.8034"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Prandoni P, Trujillo-Santos J, Surico T, Dalla Valle F, Piccioli A, Monreal M, et al. Recurrent thromboembolism and major bleeding during oral anticoagulant therapy in patients with solid cancer: Findings from the RIETE registry. <i>Haematologica<\/i> 2008; 93: 1432\u20131434.","DOI":"10.3324\/haematol.13055"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Trujillo-Santos J, Nieto JA, Tiberio G, Piccioli A, Di Micco P, Prandoni P, et al. Predicting recurrences or major bleeding in cancer patients with venous thromboembolism: Findings from the RIETE Registry. <i>Thromb Haemost<\/i> 2008; 100: 435\u2013439.","DOI":"10.1160\/TH08-02-0125"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Chee CE, Ashrani AA, Marks RS, Petterson TM, Bailey KR, Melton LJ, et al. Predictors of venous thromboembolism recurrence and bleeding among active cancer patients: A population-based cohort study. <i>Blood<\/i> 2014; 123: 3972\u20133978.","DOI":"10.1182\/blood-2014-01-549733"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. White C, Noble SIR, Watson M, Swan F, Allgar VL, Napier E, et al. Prevalence, symptom burden, and natural history of deep vein thrombosis in people with advanced cancer in specialist palliative care units (HIDDen): A prospective longitudinal observational study. <i>Lancet Haematol<\/i> 2019; 6: e79\u2013e88.","DOI":"10.1016\/S2352-3026(18)30215-1"}],"container-title":["Circulation Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/83\/11\/83_CJ-19-0515\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T23:21:56Z","timestamp":1572045716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/83\/11\/83_CJ-19-0515\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,25]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1253\/circj.cj-19-0515","relation":{},"ISSN":["1346-9843","1347-4820"],"issn-type":[{"value":"1346-9843","type":"print"},{"value":"1347-4820","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,25]]}}}