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Inoue H, Fujiki A, Origasa H, Ogawa S, Okumura K, Kubota I, et al. Prevalence of atrial fibrillation in the general population of Japan: An analysis based on periodic health examination. <i>Int J Cardiol<\/i> 2009; 137: 102\u2013107.","DOI":"10.1016\/j.ijcard.2008.06.029"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Cao L, Pokorney SD, Hayden K, Welsh-Bohmer K, Newby LK. Cognitive function: Is there more to anticoagulation in atrial fibrillation than stroke? <i>J Am Heart Assoc<\/i> 2015; 4: e001573.","DOI":"10.1161\/JAHA.114.001573"},{"key":"3","unstructured":"3. Annoni G, Mazzola P. Real-world characteristics of hospitalized frail elderly patients with atrial fibrillation: Can we improve the current prescription of anticoagulants? <i>J Geriatr Cardiol<\/i> 2016; 13: 226\u2013232."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Walker DM, Gale CP, Lip G, Martin-Sanchez FJ, McIntyre HF, Mueller C, et al. 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Quality of vitamin K antagonist control and outcomes in atrial fibrillation patients: A meta-analysis and meta-regression. <i>Thromb J<\/i> 2014; 12: 14.","DOI":"10.1186\/1477-9560-12-14"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Shimokawa H, Yamashita T, Uchiyama S, Kitazono T, Shimizu W, Ikeda T, et al. The EXPAND study: Efficacy and safety of rivaroxaban in Japanese patients with non-valvular atrial fibrillation. <i>Int J Cardiol<\/i> 2018; 258: 126\u2013132.","DOI":"10.1016\/j.ijcard.2018.01.141"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Ikeda T, Ogawa S, Kitazono T, Nakagawara J, Minematsu K, Miyamoto S, et al. Real-world outcomes of the Xarelto Post-Authorization Safety &amp; Effectiveness Study in Japanese Patients with Atrial Fibrillation (XAPASS). <i>J Cardiol<\/i> 2019; 74: 60\u201366.","DOI":"10.1016\/j.jjcc.2019.01.001"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Camm AJ, Amarenco P, Haas S, Hess S, Kirchhof P, Kuhls S, et al. XANTUS: A real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation. <i>Eur Heart J<\/i> 2016; 37: 1145\u20131153.","DOI":"10.1093\/eurheartj\/ehv466"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kim YH, Shim J, Tsai CT, Wang CC, Vilela G, Muengtaweepongsa S, et al. XANAP: A real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation in Asia. <i>J Arrhythm<\/i> 2018; 34: 418\u2013427.","DOI":"10.1002\/joa3.12073"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kusano K, Akao M, Tsuji H, Matsui K, Hiramitsu S, Hatori Y, et al. Study design of GENERAL (general practitioners and embolism prevention in NVAF patients treated with rivaroxaban: Real-life evidence): A multicenter prospective cohort study in primary care physicians to investigate the effectiveness and safety of rivaroxaban in Japanese patients with NVAF. <i>J Arrhythm<\/i> 2017; 33: 297\u2013301.","DOI":"10.1016\/j.joa.2016.12.001"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Schulman S, Kearon C. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. <i>J Thromb Haemost<\/i> 2005; 3: 692\u2013694.","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Nemoto M, Yabushita N, Kim MJ, Matsuo T, Seino S, Tanaka K. Assessment of vulnerable older adults\u2019 physical function according to the Japanese Long-Term Care Insurance (LTCI) system and Fried\u2019s criteria for frailty syndrome. <i>Arch Gerontol Geriatr<\/i> 2012; 55: 385\u2013391.","DOI":"10.1016\/j.archger.2011.10.004"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: Evidence for a phenotype. <i>J Gerontol A Biol Sci Med Sci<\/i> 2001; 56: M146\u2013M156.","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Perino AC, Fan J, Schmitt SK, Askari M, Kaiser DW, Deshmukh A, et al. Treating specialty and outcomes in newly diagnosed atrial fibrillation: From the TREAT-AF Study. <i>J Am Coll Cardiol<\/i> 2017; 70: 78\u201386.","DOI":"10.1016\/j.jacc.2017.04.054"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kim D, Yang PS, Yu HT, Kim TH, Jang E, Sung JH, et al. 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