{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T07:03:57Z","timestamp":1749884637158},"reference-count":14,"publisher":"Japanese Circulation Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Circ J"],"published-print":{"date-parts":[[2022,8,25]]},"DOI":"10.1253\/circj.cj-22-0315","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T22:11:41Z","timestamp":1659651101000},"page":"1416-1427","source":"Crossref","is-referenced-by-count":4,"title":["Thrombotic Risk Stratification and Intensive Statin Therapy for Secondary Prevention of Coronary Artery Disease\u3000\u2015 Insights From the REAL-CAD Study \u2015"],"prefix":"10.1253","volume":"86","author":[{"given":"Masahiro","family":"Natsuaki","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Saga University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Morimoto","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Hyogo College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Iimuro","sequence":"additional","affiliation":[{"name":"Innovation and Research Support Center, International University of Health and Welfare"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Retsu","family":"Fujita","sequence":"additional","affiliation":[{"name":"Innovation and Research Support Center, International University of Health and Welfare"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumi","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruo","family":"Inoue","sequence":"additional","affiliation":[{"name":"Dokkyo Medical University"},{"name":"Nasu Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihisa","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Shiga University of Medical Science"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Nishihata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, St. Luke\u2019s International Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Daida","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fujita Health University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Suwa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University Shizuoka Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Sakuma","sequence":"additional","affiliation":[{"name":"Caress Sapporo Hokko Memorial Clinic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Shiomi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotoshi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyohei","family":"Yamaji","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naritatsu","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masunori","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"St. Hill Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryozo","family":"Nagai","sequence":"additional","affiliation":[{"name":"Jichi Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kimura","sequence":"additional","affiliation":[{"name":"Hirakata Kohsai Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the REAL-CAD Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"330","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Taguchi I, Iimuro S, Iwata H, Takashima H, Abe M, Amiya E, et al. High-dose versus low-dose pitavastatin in Japanese patients with stable coronary artery disease (REAL-CAD): A randomized superiority trial. <i>Circulation<\/i> 2018; 137: 1997\u20132009.","DOI":"10.1161\/CIRCULATIONAHA.117.032615"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. <i>N Engl J Med<\/i> 2005; 352: 1425\u20131435.","DOI":"10.1056\/NEJMoa050461"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, et al. 2018 AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA Guideline on the management of blood cholesterol: Executive summary: A report of the American College of Cardiology\/American Heart Association Task Force on clinical practice guidelines. <i>Circulation<\/i> 2019; 139: e1046\u2013e1081.","DOI":"10.1161\/CIR.0000000000000624"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC\/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk. <i>Eur Heart J<\/i> 2020; 41: 111\u2013188.","DOI":"10.1093\/eurheartj\/ehz455"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Yeh RW, Secemsky EA, Kereiakes DJ, Normand SL, Gershlick AH, Cohen DJ, et al. Development and validation of a prediction rule for benefit and harm of dual antiplatelet therapy beyond 1 year after percutaneous coronary intervention. <i>JAMA<\/i> 2016; 315: 1735\u20131749.","DOI":"10.1001\/jama.2016.3775"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Costa F, van Klaveren D, James S, Heg D, Raber L, Feres F, et al. Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: A pooled analysis of individual-patient datasets from clinical trials. <i>Lancet<\/i> 2017; 389: 1025\u20131034.","DOI":"10.1016\/S0140-6736(17)30397-5"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Baber U, Mehran R, Giustino G, Cohen DJ, Henry TD, Sartori S, et al. Coronary thrombosis and major bleeding after PCI with drug-eluting stents: Risk scores from PARIS. <i>J Am Coll Cardiol<\/i> 2016; 67: 2224\u20132234.","DOI":"10.1016\/j.jacc.2016.02.064"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Natsuaki M, Morimoto T, Yamaji K, Watanabe H, Yoshikawa Y, Shiomi H, et al. Prediction of thrombotic and bleeding events after percutaneous coronary intervention: CREDO-Kyoto thrombotic and bleeding risk scores. <i>J Am Heart Assoc<\/i> 2018; 7: e008708.","DOI":"10.1161\/JAHA.118.008708"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Valgimigli M, Bueno H, Byrne RA, Collet JP, Costa F, Jeppsson A, et al. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The task force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS). <i>Eur Heart J<\/i> 2018; 39: 213\u2013260.","DOI":"10.1093\/eurheartj\/ehx638"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Nakamura M, Kimura K, Kimura T, Ishihara M, Otsuka F, Kozuma K, et al. JCS 2020 guideline focused update on antithrombotic therapy in patients with coronary artery disease. <i>Circ J<\/i> 2020; 84: 831\u2013865.","DOI":"10.1253\/circj.CJ-19-1109"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Rozemeijer R, van Bezouwen WP, van Hemert ND, Damen JA, Koudstaal S, Stein M, et al. Direct comparison of predictive performance of PRECISE-DAPT versus PARIS versus CREDO-Kyoto: A subanalysis of the ReCre8 trial. <i>Neth Heart J<\/i> 2021; 29: 201\u2013214.","DOI":"10.1007\/s12471-020-01486-y"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Yamashita D, Saito Y, Sato T, Matsumoto T, Saito K, Wakabayashi S, et al. Impact of PARIS and CREDO-Kyoto thrombotic and bleeding risk scores on clinical outcomes in patients with acute myocardial infarction. <i>Circ J<\/i> 2022; 86: 622\u2013629.","DOI":"10.1253\/circj.CJ-21-0556"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Desjobert E, Tea V, Schiele F, Ferrieres J, Simon T, Danchin N, et al. Clinical outcomes with high-intensity statins according to atherothrombotic risk stratification after acute myocardial infarction: The FAST-MI registries. <i>Arch Cardiovasc Dis<\/i> 2021; 114: 88\u201395.","DOI":"10.1016\/j.acvd.2020.06.003"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Bohula EA, Morrow DA, Giugliano RP, Blazing MA, He P, Park JG, et al. Atherothrombotic risk stratification and ezetimibe for secondary prevention. <i>J Am Coll Cardiol<\/i> 2017; 69: 911\u2013921.","DOI":"10.1016\/j.jacc.2016.11.070"}],"container-title":["Circulation Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/86\/9\/86_CJ-22-0315\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T05:20:36Z","timestamp":1715232036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/circj\/86\/9\/86_CJ-22-0315\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,25]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1253\/circj.cj-22-0315","relation":{},"ISSN":["1346-9843","1347-4820"],"issn-type":[{"type":"print","value":"1346-9843"},{"type":"electronic","value":"1347-4820"}],"subject":[],"published":{"date-parts":[[2022,8,25]]},"article-number":"CJ-22-0315"}}