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Han TS, van Leer EM, Seidell JC, Lean ME. Waist circumference action levels in the identification of cardiovascular risk factors: Prevalence study in a random sample. <i>BMJ<\/i> 1995; 311: 1401\u20131405.","DOI":"10.1136\/bmj.311.7017.1401"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Wilson PW, D\u2019Agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: The Framingham experience. <i>Arch Intern Med<\/i> 2002; 162: 1867\u20131872.","DOI":"10.1001\/archinte.162.16.1867"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Cicoira M, Maggioni AP, Latini R, Barlera S, Carretta E, Janosi A, et al. Body mass index, prognosis, and mode of death in chronic heart failure: Results from the Valsartan Heart Failure Trial. <i>Eur J Heart Fail<\/i> 2006; 9: 397\u2013402.","DOI":"10.1016\/j.ejheart.2006.10.016"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Curtis JP, Selter JG, Wang Y, Rathore SS, Jovin IS, Jadbabaie F, et al. The obesity paradox: Body mass index and outcomes in patients with heart failure. <i>Arch Intern Med<\/i> 2005; 165: 55\u201361.","DOI":"10.1001\/archinte.165.1.55"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Bucholz EM, Rathore SS, Reid KJ, Jones PG, Chan PS, Rich MW, et al. Body mass index and mortality in acute myocardial infarction patients. <i>Am J Med<\/i> 2012; 125: 796\u2013803.","DOI":"10.1016\/j.amjmed.2012.01.018"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Won KB, Hur SH, Cho YK, Yoon HJ, Nam CW, Kim KB, et al. Comparison of 2-year mortality according to obesity in stabilized patients with type 2 diabetes mellitus after acute myocardial infarction: Results from the DIAMOND prospective cohort registry. <i>Cardiovasc Diabetol<\/i> 2015; 14: 141.","DOI":"10.1186\/s12933-015-0305-1"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Won KB, Yoon HJ, Lee SG, Cho YK, Nam CW, Hur SH, et al. Comparison of long-term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug-eluting stents. <i>Catheter Cardiovasc Interv<\/i> 2018; 91: 710\u2013716.","DOI":"10.1002\/ccd.27110"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Kim BG, Hong SJ, Kim BK, Ahn CM, Shin DH, Kim JS, et al. Association between body mass index and clinical outcomes after new-generation drug-eluting stent implantation: Korean multi-center registry data. <i>Atherosclerosis<\/i> 2018; 277: 155\u2013162.","DOI":"10.1016\/j.atherosclerosis.2018.08.047"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Levine GN, Bates ER, Bittl JA, Brindis RG, Fihn SD, Fleisher LA, et al. 2016 ACC\/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines: An update of the 2011 ACCF\/AHA\/SCAI Guideline for Percutaneous Coronary Intervention, 2011 ACCF\/ AHA Guideline for Coronary Artery Bypass Graft Surgery, 2012 ACC\/AHA\/ACP\/AATS\/PCNA\/SCAI\/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease, 2013 ACCF\/AHA Guideline for the Management of ST-Elevation Myocardial Infarction, 2014 AHA\/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes, and 2014 ACC\/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery. <i>Circulation<\/i> 2016; 134: e123\u2013e155.","DOI":"10.1161\/CIR.0000000000000404"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Valgimigli M, Bueno H, Byrne RA, Collet JP, Costa F, Jeppsson A, et al. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The task force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS). <i>Eur Heart J<\/i> 2018; 39: 213\u2013260.","DOI":"10.1093\/eurheartj\/ehx638"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Neumann FJ, Sousa-Uva M, Ahlsson A, Alfonso F, Banning AP, Benedetto U, et al. 2018 ESC\/EACTS guidelines on myocardial revascularization. <i>Eur Heart J<\/i> 2019; 40: 87\u2013165.","DOI":"10.1093\/eurheartj\/ehy855"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Koo BK, Kang J, Park KW, Rhee TM, Yang HM, Won KB, et al. Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): An investigator-initiated, prospective, randomised, open-label, multicentre trial. <i>Lancet<\/i> 2021; 397: 2487\u20132496.","DOI":"10.1016\/S0140-6736(21)01063-1"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Lee H, Koo BK, Park KW, Shin ES, Lim SW, Rha SW, et al. A randomized clinical trial comparing long-term clopidogrel vs aspirin monotherapy beyond dual antiplatelet therapy after drug-eluting coronary stent implantation: Design and rationale of the Harmonizing Optimal Strategy for Treatment of coronary artery stenosis-Extended Antiplatelet Monotherapy (HOST-EXAM) trial. <i>Am Heart J<\/i> 2017; 185: 17\u201325.","DOI":"10.1016\/j.ahj.2016.12.001"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. <i>Arch Intern Med<\/i> 1998; 158: 1855\u20131867.","DOI":"10.1001\/archinte.158.17.1855"},{"key":"15","unstructured":"15. Pan WH, Yeh WT. How to define obesity? Evidence-based multiple action points for public awareness, screening, and treatment: An extension of Asian-Pacific recommendations. <i>Asia Pac J Clin Nutr<\/i> 2008; 17: 370\u2013374."},{"key":"16","unstructured":"16. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The Evidence Report. National Institutes of Health. <i>Obes Res<\/i> 1998; 6(Suppl 2): 51S\u2013209S."},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Wolny R, Maehara A, Liu Y, Zhang Z, Mintz GS, Redfors B, et al. The obesity paradox revisited: Body mass index and long-term outcomes after PCI from a large pooled patient-level database. <i>EuroIntervention<\/i> 2020; 15: 1199\u20131208.","DOI":"10.4244\/EIJ-D-19-00467"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Faggioni M, Baber U, Afshar AE, Giustino G, Sartori S, Sorrentino S, et al. Effects of body mass index on clinical outcomes in female patients undergoing percutaneous coronary intervention with drug-eluting stents: Results from a patient-level pooled analysis of randomized controlled trials. <i>JACC Cardiovasc Interv<\/i> 2018; 11: 68\u201376.","DOI":"10.1016\/j.jcin.2017.06.060"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Banack HR, Stokes A. 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