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Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study. <i>Stroke<\/i> 1991; 22: 983\u2013988.","DOI":"10.1161\/01.STR.22.8.983"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. <i>Ann Intern Med<\/i> 2007; 146: 857\u2013867.","DOI":"10.7326\/0003-4819-146-12-200706190-00007"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. van Walraven C, Hart RG, Connolly S, Austin PC, Mant J, Hobbs FD, et al. Effect of age on stroke prevention therapy in patients with atrial fibrillation. <i>Stroke<\/i> 2009; 40: 1410\u20131416.","DOI":"10.1161\/STROKEAHA.108.526988"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Akao M, Ogawa H, Masunaga N, Minami K, Ishigami K, Ikeda S, et al. 10-year trends of antithrombotic therapy status and outcomes in Japanese atrial fibrillation patients: The Fushimi AF Registry. <i>Circ J<\/i> 2022; 86: 726\u2013736.","DOI":"10.1253\/circj.CJ-22-0023"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Shen NN, Zhang C, Hang Y, Li Z, Kong LC, Wang N, et al. Real-world prevalence of direct oral anticoagulant off-label doses in atrial fibrillation: An epidemiological meta-analysis. <i>Front Pharmacol<\/i> 2021; 12: 581293.","DOI":"10.3389\/fphar.2021.581293"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Santos J, Ant\u00f3nio N, Rocha M, Fortuna A. Impact of direct oral anticoagulant off-label doses on clinical outcomes of atrial fibrillation patients: A systematic review. <i>Br J Clin Pharmacol<\/i> 2020; 86: 533\u2013547.","DOI":"10.1111\/bcp.14127"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Steinberg BA, Shrader P, Thomas L, Ansell J, Fonarow GC, Gersh BJ, et al. Off-label dosing of non-Vitamin K antagonist oral anticoagulants and adverse outcomes: The ORBIT-AF II Registry. <i>J Am Coll Cardiol<\/i> 2016; 68: 2597\u20132604.","DOI":"10.1016\/j.jacc.2016.09.966"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Camm AJ, Cools F, Virdone S, Bassand JP, Fitzmaurice DA, Fox KAA, et al. Mortality in patients with atrial fibrillation receiving nonrecommended doses of direct oral anticoagulants. <i>J Am Coll Cardiol<\/i> 2020; 76: 1425\u20131436.","DOI":"10.1016\/j.jacc.2020.07.045"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Inoue H, Yamashita T, Akao M, Atarashi H, Ikeda T, Okumura K, et al. Prospective observational study in elderly patients with non-valvular atrial fibrillation: Rationale and design of the All Nippon AF In the Elderly (ANAFIE) Registry. <i>J Cardiol<\/i> 2018; 72: 300\u2013306. Corrigendum: <i>J Cardiol<\/i> 2022; <b>80:<\/b> 375\u2013376.","DOI":"10.1016\/j.jjcc.2022.06.008"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Koretsune Y, Yamashita T, Akao M, Atarashi H, Ikeda T, Okumura K, et al. Baseline demographics and clinical characteristics in the All Nippon AF In the Elderly (ANAFIE) Registry. <i>Circ J<\/i> 2019; 83: 1538\u20131545.","DOI":"10.1253\/circj.CJ-19-0094"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Yamashita T, Suzuki S, Inoue H, Akao M, Atarashi H, Ikeda T, et al. Two-year outcomes of more than 30 000 elderly patients with atrial fibrillation: Results from the All Nippon AF In the Elderly (ANAFIE) Registry. <i>Eur Heart J Qual Care Clin Outcomes<\/i> 2022; 8: 202\u2013213.","DOI":"10.1093\/ehjqcco\/qcab025"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Akao M, Shimizu W, Atarashi H, Ikeda T, Inoue H, Okumura K, et al. Oral anticoagulant use in elderly Japanese patients with non-valvular atrial fibrillation: Subanalysis of the ANAFIE Registry. <i>Circ Rep<\/i> 2020; 2: 552\u2013559.","DOI":"10.1253\/circrep.CR-20-0082"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Tanigawa T, Kaneko M, Hashizume K, Kajikawa M, Ueda H, Tajiri M, et al. Model-based dose selection for phase III rivaroxaban study in Japanese patients with non-valvular atrial fibrillation. <i>Drug Metab Pharmacokinet<\/i> 2013; 28: 59\u201370.","DOI":"10.2133\/dmpk.DMPK-12-RG-034"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Hori M, Matsumoto M, Tanahashi N, Momomura S, Uchiyama S, Goto S, et al. Rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation: The J-ROCKET AF study. <i>Circ J<\/i> 2012; 76: 2104\u20132111.","DOI":"10.1253\/circj.CJ-12-0454"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Arbel R, Sergienko R, Hammerman A, Greenberg-Dotan S, Batat E, Avnery O, et al. 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